Calcipotriene and Calcipotriol: Identity, CAS and Drug-Label Context

Calcipotriene is the U.S. adopted name and Calcipotriol is the international name commonly used for the same vitamin D analog active moiety. PubChem CID 5288783 records the anhydrous formula C₂₇H₄₀O₃, molecular weight 412.6 g/mol and InChIKey LWQQLNNNIPYSNX-UROSTWAQSA-N. The Longchang source record and this URL use CAS 112828-00-9, but public CAS associations are not uniform, so a buyer should confirm the exact name, CAS, stereochemistry, hydration state and identity method before comparing documents, samples or quotations.

Calcipotriene identity at a glance

Identity references: PubChem CID 5288783, NIH NCATS Drugs / GSRS aggregation for UNII 143NQ3779B and the current DailyMed Calcipotriene Ointment USP label. These records support nomenclature and identity interpretation; they are not a Longchang specification, lot result, grade declaration or finished-product authorization.

Are Calcipotriene and Calcipotriol the same?

Calcipotriene is the U.S. adopted name (USAN), and Calcipotriol is the international nonproprietary name (INN) for the same active moiety. A purchase specification should state the accepted name set and the exact structural identity instead of treating the two names as separate materials.

Do not confuse either name with Vitamin D3 (cholecalciferol) or calcitriol. They are different chemical identities with different formulae and registry records. A related biological role or the phrase “vitamin D analog” does not make them interchangeable on an RFQ, formula, method or regulatory submission.

Why CAS 112828-00-9 needs document-level confirmation

The existing Longchang source record uses CAS 112828-00-9. PubChem currently shows 112965-21-6 under its CAS section, continues to associate 112828-00-9 through an ECHA contribution, and identifies 112828-00-9 as deprecated in a ChemIDplus contribution. The NCATS/GSRS aggregation also associates 112828-00-9 with the Calcipotriene active-moiety record.

This is a reason to strengthen identity controls, not to silently substitute a number. For a quotation or technical review, align the controlled product name, CAS identifier, stereochemistry, formula, molecular weight, InChIKey, hydration/solvate state, reference standard and identity method. Record any identifier difference before sample approval or use in a regulated workflow.

Anhydrous Calcipotriene versus Calcipotriene monohydrate

A finished prescription label can identify the active ingredient basis used in that named product. It does not prove which hydration state, assay basis or appearance applies to an unspecified supplier lot.

Is Calcipotriene a steroid?

FDA/DailyMed classifies Calcipotriene as a vitamin D analog. Its chemistry belongs to the secosteroid family, but it is not a corticosteroid. This distinction matters because some finished prescription products combine Calcipotriene with a separate corticosteroid active ingredient, such as betamethasone dipropionate. A combination-product label must not be used to assign the corticosteroid identity or performance to Calcipotriene alone.

What does the finished-drug label establish?

The reviewed DailyMed page is a current U.S. prescription-drug label for a named Calcipotriene Ointment USP 0.005% product. It describes that finished product’s active ingredient, formulation, route, indication, warnings, directions and clinical information. The label also states that the precise antipsoriatic action is not fully understood and separates in-vitro evidence from clinical findings.

Historical webpage fields requiring confirmation

The earlier Longchang records displayed the fields below without a visible controlled specification number, hydration basis, full method set, lot identity, effective date or approval status. They are retained only as RFQ questions—not as current specifications, lot results, grade statements or regulatory evidence.

Calcipotriene sourcing checklist

• State the accepted name set and source-record CAS, then require controlled identity confirmation.
• Specify anhydrous, monohydrate or another material basis and align formula, molecular weight and assay basis.
• Define the intended technical context, buyer quality standard and destination market.
• Provide the buyer specification or list required tests, methods, units and limits.
• Request the current supplier specification, applicable lot COA and current SDS.
• State sample quantity, full quantity, packaging constraints and destination.
• Request current MOQ, availability, quotation validity and confirmed destination-specific lead time.
• Complete the buyer’s quality, regulatory and formulation review before use.

Request current Calcipotriene source information

Open the Calcipotriene CAS 112828-00-9 sourcing page to request current identity confirmation, specification, analytical methods, applicable lot COA, SDS, sample and commercial information.

Courriel info@longchangchemical.com with the intended technical context, destination market, required identity basis, tests and limits, quantity, packaging and document requirements.

Frequently asked questions

Are Calcipotriene and Calcipotriol different ingredients?

They are alternative U.S. and international adopted names for the same active moiety. The procurement record should still align the exact identifier set, stereochemistry and hydration state.

What is the molecular formula of Calcipotriene?

The anhydrous active-moiety formula is C₂₇H₄₀O₃. A monohydrate record includes one molecule of water and has a different molecular weight.

Is Calcipotriene a corticosteroid?

No. FDA/DailyMed describes it as a vitamin D analog. Some finished combination products contain Calcipotriene together with a separate corticosteroid ingredient.

Does a DailyMed label prove Longchang material is an approved drug?

No. The label applies to the named finished prescription product. A supplier lot requires its own controlled identity, quality documents and buyer qualification.