Pharmaceutical Intermediates

tert-Butyldimethylsilyl chloride CAS 18162-48-6

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CAS number
18162-48-6
Chemical name
tert-Butyldimethylsilyl chloride
Molecular formula
C6H15ClSi
Molecular weight
150.72

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tert-Butyldimethylsilyl chlorideTypical Properties

Items Technical index
Appearance White to off-white crystal
Assay (GC) 99.0%min
Identification Peak retention time oftestsample is the same as standard sample’s (2.5% /-)
tert-Butyldimethylsilanol 0.5% max.
Melting point 86-90’C

tert-Butyldimethylsilyl chloride Usage

It is used as an auxiliary material for the synthesis of prostaglandins, certain antibiotics, hypolipidemic drugs lovastatin and simvastatin. It is used as a pharmaceutical intermediate and used in organic synthesis as a hydroxyl protecting agent in organic synthesis. It is a sterically hindered type. Silicone protective agent, widely used in the synthesis of original drugs. It is used as a protecting group for a hydroxyl group in the synthesis of ribonucleosides, and is also an oxidizing agent and a de-cyanide agent.

tert-Butyldimethylsilyl chloride Packaging

Bags, 1g,5g,1kg,25 kg
Drum,25 kg ,180kg
Or as per customers required

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