Pharmaceutical Intermediates

1,8-Diazabicyclo[5,4,0] undec-7-ene; DBU CAS 6674-22-2

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CAS number
6674-22-2
Chemical name
1,8-Diazabicyclo[5,4,0] undec-7-ene; DBU
Molecular formula
C9H16N2
Molecular weight
152.24

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1,8-Diazabicyclo[5,4,0] undec-7-ene (DBU)Typical Properties

Appearance Yellowish liquid
Assay ≥ 99%
Water ≤ 0.2%
Solubility Soluble in water

1,8-Diazabicyclo[5,4,0] undec-7-ene (DBU) Usage

The main use of DBU is as an excellent organic base deacidification agent for drug synthesis.

It can replace organic bases such as triethylamine, N,N-dimethylaniline, pyridine and quinoline, and is widely used in organic synthesis and semi-synthetic antibiotics, and obtains satisfactory results in dehydrohalogenation reaction.

It is widely used in the production of cephalosporin semi-synthetic antibiotics, such as ammonia and dichloroethane in the presence of DBU to form piperazine.

It can also be used as an epoxy resin hardener, rust inhibitor, and can be formulated as a high corrosion inhibitor for the catalysis of other chemical reactions.

Diazabicyclo DBU is used in the manufacture of cephalosporin semi-synthetic antibiotics, as well as in the preparation of deacidification agents, rust inhibitors, and advanced corrosion inhibitors.

1,8-Diazabicyclo[5,4,0] undec-7-ene (DBU) Packaging and Shipping

Packing: 25kg/drum or according to the requirement of clients.

1,8-Diazabicyclo[5,4,0] undec-7-ene (DBU) Storage

Keep in a dry place, in a sealed containers.

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