Natural Product Research and Development – Liver Injury Special Topic
The liver is the largest organ in the human body with metabolism as its main function. It is the largest digestive gland in the human body and one of the few organs that can be naturally renewed. It plays a very important role in the body’s metabolism, digestion, detoxification, immune regulation, and coagulation. Chemical liver injury is the liver injury caused by alcohol, chemical toxic substances in the environment and some drugs, and its incidence rate is positively related to the dose of chemical toxicants exposed, which is the precursor of liver disease. Further development can cause liver necrosis, fat deformation, liver fibrosis, cirrhosis, liver cancer and other serious liver diseases to varying degrees. It is one of the most common types of liver injury in clinical practice. How to effectively prevent and treat chemical liver injury, prevent its further malignant development into serious liver disease, has become a research hotspot in the field of medicine.
In recent years, with the in-depth study of chemical liver injury, natural products with advantages such as wide sources, low cost, diverse targets, and minimal toxic side effects have received widespread attention and research from researchers. These natural products can exert hepatoprotective effects through various pathways such as antioxidant, anti-inflammatory, and anti apoptotic effects. This topic aims to provide a theoretical basis for future research on the prevention and treatment of chemical liver injury by studying the relevant mechanisms of natural products in preventing and treating chemical liver injury, and to lay the foundation for further drug development.