Prothionamide (CAS 14222-60-7): Correct Identity and Technical Review

Prothionamide, also spelled protionamide, is a thioamide compound identified by CAS 14222-60-7. PubChem CID 666418 records its molecular formula as C₉H₁₂N₂S and molecular weight as 180.27 g/mol.

Correct chemical identity

The systematic name is 2-propylpyridine-4-carbothioamide. Its structure contains a pyridine ring and a carbothioamide group. It should not be described as a thiazole with a carbonyl group. That distinction matters when checking analytical data, a structure drawing or a specification supplied under a similar name.

Medical references and their limits

Prothionamide appears in antituberculosis drug references. Such references do not provide a general-purpose treatment plan for a reader or establish that a raw chemical may be used as a medicine. Tuberculosis treatment depends on resistance, the individual patient and current clinical guidance. It requires specialist medical supervision.

This website does not recommend a regimen or provide dosing instructions. A supplier description cannot establish current first-line or second-line treatment status in every country. Use current authoritative clinical guidance and the approved information for the actual finished medicine when making professional treatment decisions.

Why a structure check belongs in procurement

A name or CAS number should agree across the quotation, label, COA and reference structure. Compare the molecular formula and material form before interpreting analytical results. If a formula, molecular weight or functional-group description conflicts with the structural record, resolve that discrepancy with the supplier before proceeding.

Identity records do not determine the grade or impurity profile of a particular lot. Request the analytical methods, acceptance limits, reference-standard basis and batch documentation appropriate to the intended professional use.

Questions for technical evaluation

• Does the requested material match CAS 14222-60-7 and the reference structure?
• What is the current specification, and which method establishes identity and assay?
• Which impurities and residuals are relevant to the process?
• Which documents and supply conditions apply in the destination market?
• What handling and storage measures are specified in the current SDS?

For a technical inquiry, provide the exact identity, required grade, quantity, destination and documentation needs through our Contact page. Review our Technical & Medical Disclaimer for the boundaries of research and product information.

Reviewed and corrected: 10 September 2026. This revision corrects the formula, molecular weight and structural description and removes unsupported regimen, dosing and pharmacokinetic assertions.