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What is Aminoguanidine Hydrochloride?

Aminoguanidine Hydrochloride is a chemical compound with the molecular formula CH7ClN4 and molecular weight of 110.55 g/mol. Its IUPAC name is 2-aminoguanidine hydrochloride, and its SMILES notation is C(=NN)(N)N.Cl. This compound appears as a white to off-white crystalline powder and is highly soluble in water. As a hydrochloride salt of aminoguanidine, it is commonly used as an intermediate in various chemical synthesis processes and pharmaceutical applications.

The compound is also known by several alternative names including Aminoguanidinium chloride, Guanamine hydrochloride, and 1-Aminoguanidine hydrochloride. Its unique chemical structure featuring a guanidine group functionalized with an amino substituent makes it a versatile building block in organic synthesis and medicinal chemistry.

What Are the Benefits?

Pharmaceutical Applications

Aminoguanidine Hydrochloride has attracted significant attention in pharmaceutical research due to its diverse biological activities. The compound has been studied for its potential therapeutic applications in several areas:

Antioxidant Properties: Aminoguanidine acts as a potent antioxidant by scavenging free radicals and inhibiting the formation of advanced glycation end products (AGEs). This mechanism is particularly relevant in the context of diabetic complications and aging-related diseases.

Cardiovascular Health: Research has explored the use of aminoguanidine derivatives in cardiovascular health applications, particularly in managing complications associated with diabetes such as diabetic nephropathy and retinopathy.

Anti-inflammatory Effects: The compound demonstrates anti-inflammatory properties that make it valuable in developing treatments for various inflammatory conditions.

Industrial Benefits

In industrial applications, Aminoguanidine Hydrochloride serves as:

Chemical Intermediate: It is widely used as an intermediate in the synthesis of various nitrogen-containing heterocyclic compounds, dyes, and photographic chemicals.

Industrie des polymères: The compound finds application in the production of certain polymers and resins, where it contributes to desired material properties.

What Are the Uses?

Pharmaceutical Manufacturing

Aminoguanidine Hydrochloride is primarily used in pharmaceutical manufacturing as a key intermediate in the synthesis of:

  • Various API (Active Pharmaceutical Ingredients)
  • Cardiovascular drugs
  • Anti-diabetic medications
  • Heterocyclic pharmaceutical compounds

Research Applications

In research laboratories, this compound is utilized for:

  • Developing new drug candidates
  • Studying advanced glycation end products (AGEs)
  • Antioxidant compound research
  • Biochemical studies involving nitric oxide synthase inhibition

Applications industrielles

The industrial uses include:

  • Dye manufacturing
  • Photography chemical production
  • Polymer additive manufacturing
  • Corrosion inhibition formulations

Sécurité et manipulation

General Safety Considerations

When handling Aminoguanidine Hydrochloride, appropriate safety measures should be observed:

  • Wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and lab coat
  • Work in a well-ventilated area or fume hood
  • Avoid inhalation of dust or aerosols
  • Wash hands thoroughly after handling

Storage Requirements

  • Store in a cool, dry, well-ventilated area
  • Keep container tightly closed
  • Store away from incompatible materials
  • Follow local regulations for chemical storage

First Aid Measures

  • Eye contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Seek medical attention if irritation persists.
  • Skin contact: Wash with plenty of soap and water. Remove contaminated clothing. Seek medical attention if irritation develops.
  • Inhalation: Move to fresh air. Seek medical attention if symptoms persist.
  • Ingestion: Rinse mouth. Do NOT induce vomiting. Seek medical attention if feeling unwell.

Chemical Specifications

Numéro CAS 1937-19-5
Formule moléculaire CH7ClN4
Poids moléculaire 110.55 g/mol
IUPAC Name 2-aminoguanidine;hydrochloride
SMILES C(=NN)(N)N.Cl
Apparence Poudre cristalline blanche à blanc cassé
Solubilité Highly soluble in water
HBond Donors 4
HBond Acceptors 2
Complexity 41

Frequently Asked Questions

What is the CAS number of Aminoguanidine Hydrochloride?

The CAS number for Aminoguanidine Hydrochloride is 1937-19-5.

Is Aminoguanidine Hydrochloride safe for pharmaceutical use?

Aminoguanidine Hydrochloride is used as an intermediate in pharmaceutical manufacturing. For specific safety and regulatory information, consult relevant pharmaceutical regulatory guidelines and safety data sheets.

What is the molecular weight of Aminoguanidine Hydrochloride?

The molecular weight is 110.55 g/mol.

How should Aminoguanidine Hydrochloride be stored?

Store in a cool, dry, well-ventilated area in tightly closed containers. Keep away from incompatible materials and follow standard chemical storage protocols.

What are the main applications of this compound?

The main applications include pharmaceutical intermediate synthesis, research chemicals, dye manufacturing, and polymer industry applications.

Why Choose Our Aminoguanidine Hydrochloride?

At Longchang Chemical, we are committed to providing high-quality Aminoguanidine Hydrochloride (CAS 1937-19-5) to meet your industrial and research needs. Our product stands out for:

Quality Assurance: Every batch undergoes rigorous quality control testing to ensure purity and consistency meeting international standards.

Reliable Supply: With our robust manufacturing capabilities and supply chain, we ensure timely delivery to meet your production requirements.

Technical Support: Our team of chemical experts provides comprehensive technical support and documentation, including MSDS and certificates of analysis.

Competitive Pricing: We offer competitive pricing without compromising on quality, making us your cost-effective partner for chemical supply.

Global Shipping: We provide reliable international shipping with proper documentation for customs clearance.

Choose Longchang Chemical as your trusted supplier for Aminoguanidine Hydrochloride and experience the difference in quality and service.

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