What Is Aceglutamide?

Aceglutamide (CAS 2490-97-3), also known as acetylglutamine, is an acetylated derivative of the amino acid L-glutamine. By introducing an acetyl group onto the glutamine backbone, aceglutamide improves the stability, solubility and bioavailability of glutamine-related formulations. It has been developed into injectable and oral preparations in countries such as Spain and Japan, and is also supplied as a high-purity bulk ingredient for pharmaceutical R&D and formulation.

What Are the Benefits of Aceglutamide?

Neuroprotective and Nootropic Support

Derived from L-glutamine, the biochemical precursor of glutamate and GABA, aceglutamide may help maintain neuronal metabolism and neurotransmitter balance. It has been used in formulations intended to support recovery after brain injury, trauma or neurosurgery, and to improve alertness, cognitive function and mental performance.

Support in Coma and Neurological Recovery

Aceglutamide injection has been used as an adjunct in the management of traumatic coma, coma after neurosurgical procedures, hepatic coma, hemiplegia and high paraplegia, as well as neurological headache and lumbago. In these settings, it is combined with comprehensive medical care and is intended to improve cerebral metabolism, promote arousal and support neurological recovery.

Gastrointestinal and Anti-Ulcer Applications

Besides its neurotropic effects, aceglutamide has been reported as an antiulcer agent and gastrointestinal-supporting ingredient. As a glutamine-derived compound, it can contribute to intestinal mucosal integrity and nutritional support in some clinical nutrition formulations.

What Are the Uses of Aceglutamide?

Aceglutamide is a flexible ingredient with multiple application scenarios in the pharmaceutical and healthcare fields, including active ingredient in neurological formulations, pharmaceutical intermediate for CNS drugs, R&D applications in neuroprotection and anti-ulcer research, and potential use in nutritional and metabolic support formulations under medical supervision.

Safety and Side Effects

Aceglutamide has been used clinically in certain regions for many years, but its safety profile and regulatory status vary by country. Common considerations include general tolerability, possible adverse reactions such as gastrointestinal discomfort, nausea, headache or allergic reactions, and the need for monitoring in severe neurological conditions. It is a pharmaceutical ingredient and should only be used under the supervision of qualified healthcare professionals.

Chemical Specifications of Aceglutamide (CAS 2490-97-3)

• Product Name: Aceglutamide
• Synonyms: Acetylglutamine; N-Acetyl-L-glutamine
• CAS Number: 2490-97-3
• Formule moléculaire : C7H12N2O4
• Molecular Weight: approx. 188.18 g/mol
• Appearance: white or almost white crystalline powder
• Purity: typically ≥ 99% (HPLC)
• Solubility: freely soluble in water

Frequently Asked Questions

Is aceglutamide the same as glutamine? No. Aceglutamide is an acetylated derivative of L-glutamine with distinct properties and applications.

What dosage forms use aceglutamide? It has been formulated into injectable solutions and oral preparations, depending on local regulatory approvals and clinical practice.

Can aceglutamide be used as a dietary supplement? It is primarily positioned as a pharmaceutical ingredient. Whether it can be used in dietary supplements depends on local regulations.

Why Choose Our Aceglutamide?

We offer high-purity aceglutamide (CAS 2490-97-3) with consistent quality, pharmaceutical-grade manufacturing standards, stable supply and flexible packaging. Our technical team provides COA, MSDS and supporting data to help your formulation, registration and scale-up processes.

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