{"id":9138,"date":"2024-08-15T18:59:47","date_gmt":"2024-08-15T18:59:47","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=9138"},"modified":"2024-08-15T18:59:47","modified_gmt":"2024-08-15T18:59:47","slug":"american-cockroaches","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/ameri\u0307kan-hamambocekleri\u0307\/","title":{"rendered":"Amerikan hamamb\u00f6ceklerinden elde edilen polisakkaritlerin hidroliz s\u00fcreci ve antioksidan aktivitesi \u00fczerine ara\u015ft\u0131rma"},"content":{"rendered":"

Amerikan hamamb\u00f6ceklerinden elde edilen polisakkaritlerin hidroliz s\u00fcreci ve antioksidan aktivitesi \u00fczerine ara\u015ft\u0131rma
\nAmerikan hamamb\u00f6ce\u011fi (Periplaneta Americana L.) hamamb\u00f6ce\u011fi cinsinin en b\u00fcy\u00fck b\u00f6ceklerinden biridir. Hamamb\u00f6ceklerinin t\u0131bbi de\u011feri uzun zamand\u0131r \"Shennong Bencao Jing\" ve Ming Hanedanl\u0131\u011f\u0131'n\u0131n \"Compendium of Materia Medica \"s\u0131nda kaydedilmi\u015ftir. 1980'lerden bu yana, Profes\u00f6r Li Shunan liderli\u011findeki ara\u015ft\u0131rmac\u0131lar kendilerini Amerikan hamamb\u00f6ceklerinin t\u0131bbi ara\u015ft\u0131rmalar\u0131na adam\u0131\u015flard\u0131r. Yapay olarak yeti\u015ftirilen Amerikan hamamb\u00f6ceklerinin etanol \u00f6zleri \u00fclser, kanser ve di\u011fer durumlar\u0131n tedavisi i\u00e7in a\u011f\u0131zdan veya topikal olarak al\u0131nmaktad\u0131r. Ara\u015ft\u0131rmalar, Amerikan hamamb\u00f6ceklerinin kimyasal bile\u015fiminin proteinler, amino asitler, peptitler, \u015fekerler, ya\u011f asitleri, feromonlar ve anti-t\u00fcm\u00f6r, anti karaci\u011fer fibrozu, antibakteriyel, antiviral ve antioksidan etkiler gibi biyolojik aktivitelere sahip di\u011ferlerini i\u00e7erdi\u011fini ortaya koymu\u015ftur.<\/p>\n

Karbonhidratlar yery\u00fcz\u00fcnde en bol bulunan organik bile\u015fikler olup toplam biyok\u00fctlenin d\u00f6rtte \u00fc\u00e7\u00fcn\u00fc, polisakkaritler ise toplam\u0131n yakla\u015f\u0131k 90%'sini olu\u015fturmaktad\u0131r. Polisakkaritlerin biyolojik aktiviteleri temel olarak anti-t\u00fcm\u00f6r, hipoglisemik, anti-aging, kemik ili\u011fi hematopoetik fonksiyonunu artt\u0131rma, ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 d\u00fczenleme vb. i\u00e7erir ve temelde toksik de\u011fildirler ve yan etkileri yoktur. Bu nedenle, yayg\u0131n ilgi g\u00f6rm\u00fc\u015flerdir ve t\u0131p alan\u0131nda b\u00fcy\u00fck uygulama olanaklar\u0131na sahiptirler. Aktivitesi, ba\u011f\u0131l molek\u00fcler a\u011f\u0131rl\u0131\u011f\u0131, kimyasal bile\u015fimi, glikozidik ba\u011f konfig\u00fcrasyonu, ba\u011flant\u0131 modu ve uzamsal konfig\u00fcrasyonu ile ilgilidir. Amerikan hamamb\u00f6ce\u011fi polisakkaritlerinin \u00f6zelliklerini anlamak i\u00e7in, hidroliz reaksiyonu monosakkarit bile\u015fimi ve i\u00e7eri\u011findeki de\u011fi\u015fiklikleri analiz etmek i\u00e7in kullan\u0131labilir ve Amerikan hamamb\u00f6ce\u011fi polisakkaritlerinin kalite kontrol\u00fc i\u00e7in bir temel sa\u011flar. Deneyde deneysel nesne olarak Amerikan hamamb\u00f6ce\u011fi polisakkaritleri kullan\u0131lm\u0131\u015ft\u0131r. Tek fakt\u00f6rl\u00fc deneylere dayanarak, y\u00fcksek performansl\u0131 s\u0131v\u0131 kromatografisindeki monosakkaritlerin toplam pik alan\u0131, en y\u00fcksek monosakkarit i\u00e7eri\u011fini elde etmek i\u00e7in yan\u0131t y\u00fczeyi metodolojisi kullan\u0131larak Amerikan hamamb\u00f6ce\u011fi polisakkaritlerinin hidroliz s\u00fcrecini optimize etmek i\u00e7in g\u00f6sterge olarak kullan\u0131lm\u0131\u015ft\u0131r. Buna ek olarak, Amerikan hamamb\u00f6ce\u011fi polisakkaritlerinin antioksidan aktivitesi incelenmi\u015f ve Amerikan hamamb\u00f6ce\u011fi polisakkaritlerinin yap\u0131sal tan\u0131mlanmas\u0131 ve daha sonra geli\u015ftirilmesi ve kullan\u0131lmas\u0131 i\u00e7in referans sa\u011flanm\u0131\u015ft\u0131r.<\/p>\n

Bu \u00e7al\u0131\u015fmada, Amerikan hamamb\u00f6ce\u011fi polisakkaritlerinin ekstraksiyon i\u015flem ko\u015fullar\u0131n\u0131 optimize etmek ve antioksidan kapasitelerini \u00f6nceden de\u011ferlendirmek i\u00e7in tek fakt\u00f6rl\u00fc deneyler ve yan\u0131t y\u00fczeyi deneylerinin bir kombinasyonu kullan\u0131lm\u0131\u015ft\u0131r. Amerikan hamamb\u00f6ce\u011fi polisakkaritlerinin hidrolizi i\u00e7in en uygun i\u015flem ko\u015fullar\u0131 \u015funlard\u0131r: 1 saatlik hidroliz s\u00fcresi, 120 \u2103 hidroliz s\u0131cakl\u0131\u011f\u0131, 3,5 mL TFA dozaj\u0131 ve 4740,15 toplam pik alan\u0131. Antioksidan aktivite testinin sonu\u00e7lar\u0131, Amerikan hamamb\u00f6ceklerinden elde edilen polisakkaritlerin iyi antioksidan aktiviteye sahip oldu\u011funu ve s\u0131ras\u0131yla 0.028, 0.78 ve 0.07 mg\/mL IC50 de\u011ferleri ile DPPH, OH ve ABTS serbest radikallerine kar\u015f\u0131 iyi s\u00fcp\u00fcrme yetene\u011fine sahip olduklar\u0131n\u0131 ve belirli indirgeme yetene\u011fine sahip olduklar\u0131n\u0131 g\u00f6stermi\u015ftir. Zhang ve arkada\u015flar\u0131, Bawanghua polisakkaritlerindeki galaktoz ve arabinoz oran\u0131 ile ABTS serbest radikallerini temizlemek i\u00e7in IC50 aras\u0131nda belirli bir pozitif korelasyon bulmu\u015flard\u0131r. Shang ve ark. be\u015f yenilebilir mantar polisakkaritinin kimyasal bile\u015fimi ve monosakkarit bile\u015fimi ile antioksidan aktiviteleri (IC50) aras\u0131nda Pearson korelasyon analizi yapm\u0131\u015f ve fukoz, mannoz ve galaktoz i\u00e7eri\u011finin polisakkaritlerin ABTS serbest radikal temizleme aktivitesi \u00fczerinde etkisi oldu\u011funu bulmu\u015ftur; Glikoz ve mannoz i\u00e7eri\u011fi polisakkaritlerin OH radikal s\u00fcp\u00fcrme aktivitesi \u00fczerinde \u00f6nemli bir etkiye sahipken, fukoidan i\u00e7eri\u011fi polisakkaritlerdeki s\u00fcperoksit anyonlar\u0131n\u0131n IC50 de\u011feri ile pozitif ili\u015fkilidir. Ai, mannoz, ksiloz, galaktoz ve arabinozun \u00e7ay polisakkaritlerinin antioksidan aktivitesi \u00fczerinde \u00f6nemli bir etkiye sahip oldu\u011funu bulmu\u015ftur. \u0130lgili literat\u00fcr, polisakkaritlerin antioksidan aktivitesinin monosakkarit kompozisyonlar\u0131 ve her bir monosakkaritin i\u00e7eri\u011fi ile yak\u0131ndan ili\u015fkili oldu\u011funu g\u00f6stermektedir. Deney, Amerikan hamamb\u00f6ce\u011fi polisakkaritlerinin DPPH, OH ve ABTS serbest radikallerine kar\u015f\u0131 iyi bir s\u00fcp\u00fcrme kabiliyetine sahip oldu\u011funu ortaya koymu\u015ftur. HPLC test sonu\u00e7lar\u0131, hidrolizatlar\u0131n\u0131n 17.0:13.2:9.6:53.4:21.8:1.0:4.6:1.3 molar oran\u0131nda mannoz, glukoz, galaktoz, ksiloz, arabinoz ve fukoz i\u00e7erdi\u011fini g\u00f6stermi\u015ftir. Amerikan hamamb\u00f6ce\u011fi polisakkaritlerinin antioksidan aktivitesi monosakkarit bile\u015fimleriyle ili\u015fkili olabilir ve hidrolize Amerikan hamamb\u00f6ce\u011fi polisakkaritlerinin antioksidan aktivitesinin korunup korunamayaca\u011f\u0131 veya art\u0131r\u0131l\u0131p art\u0131r\u0131lamayaca\u011f\u0131 deneylerde daha fazla \u00e7al\u0131\u015f\u0131lmaya devam etmektedir.<\/p>","protected":false},"excerpt":{"rendered":"

Amerikan hamamb\u00f6ceklerinden elde edilen polisakkaritlerin hidroliz s\u00fcreci ve antioksidan aktivitesi \u00fczerine ara\u015ft\u0131rma Amerikan hamamb\u00f6ce\u011fi (Periplaneta Americana L.) hamamb\u00f6ce\u011fi cinsinin en b\u00fcy\u00fck b\u00f6ceklerinden biridir. Hamamb\u00f6ceklerinin t\u0131bbi de\u011feri uzun zamand\u0131r \"Shennong Bencao Jing\" ve Ming Hanedanl\u0131\u011f\u0131'n\u0131n \"Compendium of Materia Medica\" adl\u0131 eserlerinde kaydedilmi\u015ftir. 1980'lerden beri ara\u015ft\u0131rmac\u0131lar [...]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nResearch on the hydrolysis process and antioxidant activity of polysaccharides from American cockroaches - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/ameri\u0307kan-hamambocekleri\u0307\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research on the hydrolysis process and antioxidant activity of polysaccharides from American cockroaches - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Research on the hydrolysis process and antioxidant activity of polysaccharides from American cockroaches The American cockroach (Periplaneta Americana L.) is one of the largest insects in the cockroach genus. 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