{"id":9103,"date":"2024-08-15T18:37:39","date_gmt":"2024-08-15T18:37:39","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=9103"},"modified":"2024-08-15T18:37:39","modified_gmt":"2024-08-15T18:37:39","slug":"nine-sun-dried-rehmannia-glutinosa","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/dokuz-guneste-kurutulmus-rehmannia-glutinosa\/","title":{"rendered":"Dokuz buharda pi\u015firilmi\u015f ve dokuz g\u00fcne\u015fte kurutulmu\u015f Rehmannia glutinosa'da mor keton bile\u015fikleri"},"content":{"rendered":"

Dokuz buharda pi\u015firilmi\u015f ve dokuz g\u00fcne\u015fte kurutulmu\u015f Rehmannia glutinosa'da mor keton bile\u015fikleri
\nScrophulariaceae familyas\u0131ndaki Rehmannia glutinosa cinsinin taze veya kurutulmu\u015f bir k\u00f6k\u00fc olan Rehmannia glutinosa Libosch. geleneksel \u00c7in t\u0131bb\u0131nda binlerce y\u0131ll\u0131k bir t\u0131bbi ge\u00e7mi\u015fe sahiptir. \u00dcretim alanlar\u0131 esas olarak Henan, Shanxi, Shandong ve di\u011fer yerlerde yo\u011funla\u015fm\u0131\u015ft\u0131r ve Henan'daki Jiaozuo otantik \u00fcretim alan\u0131d\u0131r. \u015eu anda, \u00e7e\u015fitli b\u00f6lgelerde de yayg\u0131n olarak yeti\u015ftirilmektedir. Klinik ila\u00e7 tedavisinde, Radix Rehmanniae'nin \u00fc\u00e7 formu vard\u0131r: taze Radix Rehmanniae, ham Radix Rehmanniae ve Radix Rehmanniae Rehmanniae. Bunlar\u0131n klinik uygulamalar\u0131 ve farmakolojik etkileri aras\u0131nda \u00f6nemli farkl\u0131l\u0131klar vard\u0131r. Taze Rehmannia tatl\u0131 bir tada, ac\u0131 ve so\u011fuk bir yap\u0131ya sahiptir. Kalp, karaci\u011fer ve b\u00f6brek meridyenleri. Is\u0131y\u0131 temizleme, s\u0131v\u0131 \u00fcretme, kan\u0131 so\u011futma ve kanamay\u0131 durdurma etkilerine sahiptir. Yerli sar\u0131, tatl\u0131 ve so\u011fuk bir yap\u0131ya sahiptir. Kalp, karaci\u011fer ve b\u00f6brek meridyenleri. Is\u0131y\u0131 temizleme, kan\u0131 so\u011futma, yin'i besleme ve s\u0131v\u0131 \u00fcretme etkilerine sahiptir. Rehmanniae Radix Praeparata, tatl\u0131 ve hafif \u0131l\u0131k bir tada sahip ham Rehmanniae'nin i\u015flenmi\u015f bir \u00fcr\u00fcn\u00fcd\u00fcr ve karaci\u011fer ve b\u00f6brek meridyenleri taraf\u0131ndan d\u00fczenlenir. Kan ve yini besler, \u00f6z\u00fc besler ve ili\u011fi doldurur. \u00d6n ara\u015ft\u0131rma grubu, taze Rehmannia glutinosa, Rehmannia yapraklar\u0131 ve \u00e7i\u011f Rehmannia glutinosa \u00fczerinde sistematik kimyasal bile\u015fim \u00e7al\u0131\u015fmalar\u0131 y\u00fcr\u00fctm\u00fc\u015f ve ayr\u0131ca dokuz buharda pi\u015firilmi\u015f ve dokuz g\u00fcne\u015fte kurutulmu\u015f Rehmannia glutinosa'dan alt\u0131 alkaloid bile\u015fi\u011fi izole etmi\u015ftir. \u015eu anda, ara\u015ft\u0131rma raporlar\u0131 Rehmannia glutinosa'n\u0131n esas olarak polisakkaritler, feniletanoid glikozitler, n\u00fckleozitler, sikloheksen eter terpenler, iyononlar ve \u00e7e\u015fitli eser elementler i\u00e7erdi\u011fini g\u00f6stermektedir. Rehmannia glutinosa'n\u0131n modern farmakolojik aktiviteleri temel olarak anti-t\u00fcm\u00f6r, antioksidan stres, antidepresan ve anti mutasyon etkileri olarak ortaya \u00e7\u0131kmaktad\u0131r.<\/p>\n

Menek\u015fe keton bile\u015fikleri, siklik izopren yap\u0131sal birimleri ve g\u00fc\u00e7l\u00fc anti-t\u00fcm\u00f6r aktivitesi ile Rehmannia cinsi bitkilerde yayg\u0131n olarak bulunur. \u00c7al\u0131\u015fmalar, iyonon bile\u015fiklerinin fare melanom (B16) h\u00fccreleri \u00fczerinde inhibit\u00f6r etkilere sahip oldu\u011funu g\u00f6stermi\u015ftir. Bu nedenle, bu deneyde dokuz buharda ve dokuz g\u00fcne\u015fte kurutulmu\u015f Rehmannia glutinosa'dan izole edilen iyonon bile\u015fiklerinin insan melanom A375 h\u00fccrelerindeki sitotoksik aktivitesi \u00fczerine bir tarama \u00e7al\u0131\u015fmas\u0131 yap\u0131lm\u0131\u015ft\u0131r. \"Dokuz buharda ve dokuz g\u00fcne\u015fte kurutulmu\u015f\" Rehmannia glutinosa'n\u0131n ilgili kimyasal bile\u015fenleri \u00fczerine yap\u0131lan ara\u015ft\u0131rmay\u0131 zenginle\u015ftirdi ve geli\u015ftirdi ve daha ileri anti-t\u00fcm\u00f6r ara\u015ft\u0131rmalar\u0131 i\u00e7in belirli bir referans de\u011feri sa\u011flad\u0131.<\/p>\n

Rehmannia glutinosa, Scrophulariaceae familyas\u0131ndan Rehmannia bitkisinin taze veya kurutulmu\u015f k\u00f6k yumrular\u0131d\u0131r. Klinik uygulamada \u00fc\u00e7 \u015fekilde i\u015flenir ve kullan\u0131l\u0131r: taze Rehmannia glutinosa, \u00e7i\u011f Rehmannia glutinosa ve pi\u015fmi\u015f Rehmannia glutinosa. Rehmannia glutinosa'n\u0131n i\u015flenmesi s\u0131ras\u0131nda, t\u0131bbi ve farmakolojik \u00f6zellikleri de\u011fi\u015fmi\u015ftir, bu da i\u00e7 kimyasal bile\u015fimindeki de\u011fi\u015fikliklerle yak\u0131ndan ili\u015fkili olabilir. \u00c7al\u0131\u015fmalar, i\u015fleme s\u0131ras\u0131nda Rehmannia glutinosa'daki 5-hidroksimetilfurfural (5-HMF) i\u00e7eri\u011finin ham Rehmannia glutinosa'dakinden \u00f6nemli \u00f6l\u00e7\u00fcde daha y\u00fcksek oldu\u011funu g\u00f6stermi\u015ftir. Zou ve arkada\u015flar\u0131 Rehmannia glutinosa'daki d\u00f6rt feniletanolik glikozidi ayn\u0131 anda belirlemek i\u00e7in tek test \u00e7oklu de\u011ferlendirme y\u00f6ntemini kullanm\u0131\u015f ve sonu\u00e7lar Rehmannia glutinosa'daki d\u00f6rt feniletanolik glikozidin t\u00fcm\u00fcn\u00fcn i\u00e7eri\u011finin i\u015flemden sonra azald\u0131\u011f\u0131n\u0131 g\u00f6stermi\u015ftir. Li ve arkada\u015flar\u0131n\u0131n ara\u015ft\u0131rmas\u0131, \u00e7i\u011f Rehmannia glutinosa'daki digoksin A ve digoksin D i\u00e7eri\u011finin pi\u015fmi\u015f Rehmannia glutinosa'dakinden daha y\u00fcksek oldu\u011funu g\u00f6stermi\u015ftir. Jia ve arkada\u015flar\u0131 taze, \u00e7i\u011f ve pi\u015fmi\u015f Rehmannia glutinosa'n\u0131n i\u015flenmesi s\u0131ras\u0131nda rafinoz i\u00e7eri\u011findeki de\u011fi\u015fiklikleri incelemi\u015ftir. Sonu\u00e7lar, taze Rehmannia glutinosa'n\u0131n en y\u00fcksek rafinoz i\u00e7eri\u011fine sahip oldu\u011funu, bunu \u00e7i\u011f Rehmannia glutinosa'n\u0131n izledi\u011fini ve pi\u015fmi\u015f Rehmannia glutinosa'n\u0131n en d\u00fc\u015f\u00fck i\u00e7eri\u011fe sahip oldu\u011funu g\u00f6stermi\u015ftir. Zhang ve arkada\u015flar\u0131, HPLC kullanarak \u00e7i\u011f Rehmannia glutinosa ve Rehmannia glutinosa'daki be\u015f glikozitin i\u00e7eri\u011fini e\u015fzamanl\u0131 olarak belirlemek i\u00e7in bir y\u00f6ntem olu\u015fturarak, \u00e7i\u011f Rehmannia glutinosa'n\u0131n farmakolojik madde temelinin ve Rehmannia glutinosa haz\u0131rlamak i\u00e7in farkl\u0131 i\u015fleme y\u00f6ntemlerinin incelenmesi i\u00e7in bir referans sa\u011flam\u0131\u015ft\u0131r. Rehmannia glutinosa'n\u0131n kimyasal bile\u015fimini desteklemek ve geli\u015ftirmek ve Rehmannia glutinosa'n\u0131n i\u015flenmesi s\u0131ras\u0131nda farkl\u0131 bile\u015fenleri tan\u0131mlamak i\u00e7in Rehmannia glutinosa'n\u0131n kimyasal bile\u015fenleri \u00fczerinde ara\u015ft\u0131rma yapmak gereklidir. Bu deney, \u00f6nceki ara\u015ft\u0131rmalara dayanmaktad\u0131r ve dokuz buharda pi\u015firilmi\u015f ve dokuz g\u00fcne\u015fte kurutulmu\u015f Rehmannia glutinosa'n\u0131n kimyasal bile\u015fiminin ayr\u0131lmas\u0131 ve safla\u015ft\u0131r\u0131lmas\u0131 ile \u00fc\u00e7 menek\u015fe keton bile\u015fi\u011finin izole edilmesiyle sonu\u00e7lanan ileri \u00e7al\u0131\u015fmalara dayanmaktad\u0131r. A375 sitotoksik aktivitesi \u00fczerine \u00f6n tarama ve de\u011ferlendirme \u00e7al\u0131\u015fmalar\u0131 yap\u0131lm\u0131\u015ft\u0131r. Ara\u015ft\u0131rma sonu\u00e7lar\u0131, 1-3 bile\u015fiklerinin A375 h\u00fccrelerinin canl\u0131l\u0131\u011f\u0131n\u0131 \u00f6nemli \u00f6l\u00e7\u00fcde inhibe edebildi\u011fini ve potansiyel anti insan melanom h\u00fccresi etkilerine sahip oldu\u011funu g\u00f6stermektedir. Bu deney, Rehmannia glutinosa'daki violet keton bile\u015fiklerinin insan melanom h\u00fccreleri \u00fczerindeki sitotoksik aktivitesinin mekanizmas\u0131n\u0131n incelenmesi i\u00e7in referans de\u011fer sa\u011flar ve ayr\u0131ca Rehmannia glutinosa t\u0131bbi malzemelerinin daha da geli\u015ftirilmesi ve kullan\u0131lmas\u0131 i\u00e7in bilimsel temel sa\u011flar.<\/p>","protected":false},"excerpt":{"rendered":"

Dokuz buharda pi\u015firilmi\u015f ve dokuz g\u00fcne\u015fte kurutulmu\u015f Rehmannia glutinosa'daki mor keton bile\u015fikleri Scrophulariaceae familyas\u0131ndaki Rehmannia glutinosa cinsinin taze veya kurutulmu\u015f bir k\u00f6k\u00fc olan Rehmannia glutinosa Libosch. geleneksel \u00c7in t\u0131bb\u0131nda binlerce y\u0131ll\u0131k bir t\u0131bbi ge\u00e7mi\u015fe sahiptir. \u00dcretim alanlar\u0131 \u00e7o\u011funlukla Henan, Shanxi, Shandong ve di\u011fer yerlerde yo\u011funla\u015fm\u0131\u015ft\u0131r ve [...]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nViolet ketone compounds in nine steamed and nine sun dried Rehmannia glutinosa - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/dokuz-guneste-kurutulmus-rehmannia-glutinosa\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Violet ketone compounds in nine steamed and nine sun dried Rehmannia glutinosa - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Violet ketone compounds in nine steamed and nine sun dried Rehmannia glutinosa Rehmannia glutinosa Libosch., a fresh or dried root of the Rehmannia glutinosa genus in the family Scrophulariaceae, has a medicinal history of thousands of years in traditional Chinese medicine. 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