{"id":9069,"date":"2024-08-15T18:15:58","date_gmt":"2024-08-15T18:15:58","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=9069"},"modified":"2024-08-15T18:15:58","modified_gmt":"2024-08-15T18:15:58","slug":"quinoa-bran-and-saponins","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/kinoa-kepegi-ve-saponinler\/","title":{"rendered":"Yan\u0131t y\u00fczey metodolojisi kullan\u0131larak kinoa kepe\u011fi ve saponinlerinin optimum ekstraksiyon i\u015fleminin ve \u03b1-glukozidaz inhibit\u00f6r aktivitesinin optimizasyonu"},"content":{"rendered":"

Yan\u0131t y\u00fczey metodolojisi kullan\u0131larak kinoa kepe\u011fi ve saponinlerinin optimum ekstraksiyon i\u015fleminin ve \u03b1-glukozidaz inhibit\u00f6r aktivitesinin optimizasyonu
\nChenopodium quinoa Willd. G\u00fcney Amerika'n\u0131n And Da\u011flar\u0131 b\u00f6lgesine \u00f6zg\u00fcd\u00fcr ve \u0130nka yerli halk\u0131n\u0131n ana geleneksel g\u0131das\u0131d\u0131r. T\u00fcketim ve yeti\u015ftiricili\u011finin 5000 ila 7000 y\u0131ll\u0131k bir ge\u00e7mi\u015fi vard\u0131r. Kinoa zengin besin de\u011ferine sahiptir, toplam fenoller ve flavonoller a\u00e7\u0131s\u0131ndan zengindir ve antioksidan, ba\u011f\u0131\u015f\u0131kl\u0131k d\u00fczenleyici ve antikanser aktivitelere sahiptir. 1960'lar\u0131n ba\u015f\u0131nda \u00c7in, kinoa kaynaklar\u0131n\u0131 tan\u0131tmaya ba\u015flad\u0131. Son y\u0131llarda \u00c7in'de kinoa ekim alan\u0131 h\u0131zla geni\u015fledi. 2019 y\u0131l\u0131nda, \u00c7in'deki tahmini kinoa ekim alan\u0131 20000 metrekareyi a\u015ft\u0131 ve toplam \u00fcretim 20000 ila 30000 ton aras\u0131nda ger\u00e7ekle\u015fti. Kinoa kepe\u011fi (yani kinoan\u0131n d\u0131\u015f tohum kabu\u011fu) b\u00fcy\u00fck miktarda triterpenoid saponin i\u00e7erir, ancak saponinlerin ac\u0131 bir tad\u0131 vard\u0131r. Kinoa t\u00fcketilmeden \u00f6nce, genellikle y\u0131kama veya \u00f6\u011f\u00fctme yoluyla kepe\u011fi al\u0131n\u0131r, bu nedenle kinoan\u0131n ger\u00e7ek \u00fcretimi ve i\u015flenmesi s\u0131ras\u0131nda b\u00fcy\u00fck miktarda kinoa kepe\u011fi \u00fcretilir. Bununla birlikte, kinoa kepe\u011finin mevcut kullan\u0131m\u0131 sadece yem olarak kullan\u0131m i\u00e7in basit bir i\u015flemdir. Kinoa kepe\u011fi de\u011ferlendirilebilirse, kinoan\u0131n kapsaml\u0131 kullan\u0131m de\u011feri geli\u015ftirilebilir. Triterpen saponinler anti-enflamatuar, anti-t\u00fcm\u00f6r, anti ateroskleroz ve anti diyabet aktivitelerine sahiptir. Ayr\u0131ca, kinoa kepe\u011findeki alb\u00fcminin antioksidan ve ACE inhibit\u00f6r aktivitelere sahip oldu\u011fu bildirilmi\u015ftir. 50% etanol ekstresi, antioksidan enzim sistemini aktive ederek ve TGF - \u03b2 1 yolunu bloke ederek farelerde karbon tetraklor\u00fcr kaynakl\u0131 karaci\u011fer hasar\u0131 ve fibrozis \u00fczerinde koruyucu etkilere sahiptir. Ayn\u0131 zamanda, \u00e7al\u0131\u015fmalar i\u015flenmemi\u015f kinoadan elde edilen polifenollerin ve saponin ekstraktlar\u0131n\u0131n \u03b1-glukozidaz \u00fczerinde y\u00fcksek inhibit\u00f6r aktiviteye sahip oldu\u011funu bulmu\u015ftur.<\/p>\n

\u015eu anda, kinoa kepe\u011finden toplam saponinlerin ultrasonik ekstraksiyon s\u00fcreci hakk\u0131nda ilgili literat\u00fcr raporlar\u0131 bulunmamaktad\u0131r. Bu deneyde, toplam saponinlerin ultrasonik ekstraksiyon s\u00fcrecini optimize etmek i\u00e7in deney materyali olarak kinoa kepe\u011fi kullan\u0131lm\u0131\u015ft\u0131r. Tek fakt\u00f6rl\u00fc deneyler temelinde, s\u0131v\u0131-madde oran\u0131, etanol konsantrasyonu, ultrason s\u00fcresi ve ultrason s\u0131cakl\u0131\u011f\u0131 ba\u011f\u0131ms\u0131z de\u011fi\u015fkenler olarak se\u00e7ildi ve kinoa kepe\u011finden toplam saponinlerin ekstraksiyon verimi yan\u0131t de\u011feri olarak kullan\u0131ld\u0131. Yan\u0131t y\u00fczey metodolojisi, kinoa kepe\u011finden toplam saponinlerin ultrason ekstraksiyon s\u00fcrecini optimize etmek i\u00e7in kullan\u0131lm\u0131\u015ft\u0131r. Bu deneyde, optimum ekstraksiyon i\u015flemi ko\u015fullar\u0131 alt\u0131nda ekstrakt\u0131n alfa glukozidaz \u00fczerindeki inhibit\u00f6r aktivitesi de incelenmi\u015ftir. Ayn\u0131 zamanda, inhibisyon kineti\u011fini analiz etmek i\u00e7in bir enzim reaksiyon kineti\u011fi denklemi olu\u015fturulmu\u015f ve kinoa kepe\u011finin bir alfa glukozidaz inhibit\u00f6r\u00fc olarak geli\u015fme potansiyelini ke\u015ffetmek ve kinoa kepe\u011finin daha fazla geli\u015ftirilmesi ve kullan\u0131lmas\u0131 i\u00e7in teorik temel ve veri deste\u011fi sa\u011flamak amac\u0131yla kinoa kepe\u011fi ekstrakt\u0131n\u0131n alfa glukozidaz \u00fczerindeki inhibisyon mekanizmas\u0131 ara\u015ft\u0131r\u0131lm\u0131\u015ft\u0131r.<\/p>\n

Kinoa kepe\u011finden saponinlerin ultrasonik ekstraksiyonu i\u00e7in optimum s\u00fcre\u00e7, 15 mL\/g s\u0131v\u0131\/malzeme oran\u0131, 75% etanol ultrasonik ekstraksiyon, 1,5 saat ultrasonik s\u00fcre ve 45 \u2103 ultrasonik s\u0131cakl\u0131k ile yan\u0131t y\u00fczey metodolojisi kullan\u0131larak optimize edilmi\u015ftir. Toplam saponin ekstraksiyon verimi 2.370% \u00b1 0.022% olmu\u015ftur. Bu i\u015flem basit ko\u015fullara, kolay kullan\u0131m ve kontrole, iyi bir stabiliteye sahiptir ve geleneksel y\u00f6ntemlerin uzun ekstraksiyon s\u00fcresi ve zahmetli \u0131s\u0131tma i\u015flemi ad\u0131mlar\u0131 gibi dezavantajlar\u0131n\u0131n \u00fcstesinden gelir.<\/p>\n

\u03b1-glukozidaz\u0131n inhibit\u00f6r aktivitesi \u00fczerine yap\u0131lan deney, kinoa kepe\u011finin toplam saponin ekstrakt\u0131n\u0131n piyasada bulunan \u03b1-glukozidaz inhibit\u00f6r\u00fc akarbozdan \u00f6nemli \u00f6l\u00e7\u00fcde daha g\u00fc\u00e7l\u00fc inhibit\u00f6r aktiviteye sahip oldu\u011funu g\u00f6stermi\u015ftir (P<0.05) ve bundan g\u00fcvenli ve etkili \u03b1-glukozidaz inhibit\u00f6rlerinin izole edilmesi beklenmektedir. \u0130nhibisyon mekanizmas\u0131 ve enzim kineti\u011fi \u00e7al\u0131\u015fmalar\u0131, kinoa kepe\u011finin toplam saponin ekstrakt\u0131n\u0131n tersinir bir kar\u0131\u015f\u0131k inhibisyon tipi oldu\u011funu g\u00f6stermi\u015ftir; bu, yemek sonras\u0131 kan glikozunu azaltmada kinoa kepe\u011fi ekstrakt\u0131n\u0131n mekanizmas\u0131n\u0131 a\u00e7\u0131kl\u0131\u011fa kavu\u015fturmak i\u00e7in bir referans sa\u011flar ve y\u00fcksek de\u011ferli kullan\u0131m\u0131 i\u00e7in veri temeli ve teknik destek sa\u011flar. Buna ek olarak, kinoa kepe\u011finin alfa glukozidaz inhibisyonundaki aktif madde temeli ve in vivo aktivitesi, izolasyon ve haz\u0131rlaman\u0131n yan\u0131 s\u0131ra ilgili hayvan modellerinin olu\u015fturulmas\u0131 yoluyla daha fazla incelenebilir.<\/p>\n

 <\/p>","protected":false},"excerpt":{"rendered":"

Yan\u0131t y\u00fczey metodolojisi kullan\u0131larak kinoa kepe\u011fi ve saponinlerin optimum ekstraksiyon i\u015fleminin ve \u03b1-glukozidaz inhibit\u00f6r aktivitesinin optimizasyonu Chenopodium quinoa Willd. G\u00fcney Amerika'n\u0131n And Da\u011flar\u0131 b\u00f6lgesine \u00f6zg\u00fcd\u00fcr ve \u0130nka yerli halk\u0131n\u0131n ana geleneksel g\u0131das\u0131d\u0131r. T\u00fcketim ve yeti\u015ftirme ge\u00e7mi\u015fi [...] \u00fczerinde bir tarihe sahiptir.<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nOptimization of the optimal extraction process and \u03b1 - glucosidase inhibitory activity of quinoa bran and saponins using response surface methodology - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/kinoa-kepegi-ve-saponinler\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Optimization of the optimal extraction process and \u03b1 - glucosidase inhibitory activity of quinoa bran and saponins using response surface methodology - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Optimization of the optimal extraction process and \u03b1 – glucosidase inhibitory activity of quinoa bran and saponins using response surface methodology Chenopodium quinoa Willd. is native to the Andes mountain region of South America and is the main traditional food of the Inca indigenous people. 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