Kaba dall\u0131 alt\u0131n \u015feftalide phloroglucinol bile\u015fenleri \u00fczerine \u00e7al\u0131\u015fma
\nGuttiferae familyas\u0131 ve Hypericum cinsi bitkiler, \u00f6zellikle Do\u011fu \u00c7in, Bat\u0131 \u00c7in, kuzey Sichuan, Guizhou, Xinjiang ve daha yo\u011fun olduklar\u0131 di\u011fer b\u00f6lgelerde olmak \u00fczere \u00fclke genelinde da\u011f\u0131l\u0131m g\u00f6stermektedir. \u00c7in'de 55 t\u00fcr ve 8 alt t\u00fcr olmak \u00fczere d\u00fcnya \u00e7ap\u0131nda yakla\u015f\u0131k 400 t\u00fcr\u00fc bulunmaktad\u0131r. Bu bitki, halk t\u0131bb\u0131nda 2400 y\u0131l\u0131 a\u015fk\u0131n bir t\u0131bbi ge\u00e7mi\u015fe sahiptir ve ba\u015fl\u0131ca \u0131s\u0131y\u0131 temizleme ve detoksifiye etme, kan staz\u0131n\u0131 da\u011f\u0131tma ve a\u011fr\u0131y\u0131 hafifletme ve r\u00fczgar ve rutubeti giderme etkilerine sahiptir. Primus cinsinin bitkileri esas olarak naftokinon, flavonoid, kaempferol ve phloroglucinol bile\u015fenleri i\u00e7erir; bunlar aras\u0131nda phloroglucinol bile\u015fenleri yeni kimyasal yap\u0131lar\u0131 ve \u00e7e\u015fitli farmakolojik aktiviteleri nedeniyle \u00e7ok dikkat \u00e7ekmi\u015ftir.
\nHypericum scarrum, \u00c7in'in Xinjiang b\u00f6lgesine endemik olan ve sadece Tianshan Da\u011f\u0131, Altar Da\u011f\u0131 Taishan Da\u011f\u0131, Talbahatai Da\u011f\u0131'n\u0131n \u00f6n da\u011f\u0131 ve orta da\u011fl\u0131k alanlarda da\u011f\u0131l\u0131m g\u00f6steren \u00e7ok y\u0131ll\u0131k bir Hypericum bitkisidir. Farmakolojik madde temelini daha fazla a\u00e7\u0131kl\u0131\u011fa kavu\u015fturmak ve yeni yap\u0131lara ve iyi farmakolojik aktiviteye sahip \u00f6nc\u00fc bile\u015fikler aramak i\u00e7in, bu \u00e7al\u0131\u015fma Scutellaria barbata'n\u0131n hava k\u0131sm\u0131n\u0131n etanol ekstresinden petrol eteri ekstresinin kimyasal bile\u015fenlerini izole etti, safla\u015ft\u0131rd\u0131 ve yap\u0131sal olarak tan\u0131mlad\u0131 ve her bir bile\u015fi\u011fin glutamat kaynakl\u0131 n\u00f6ronal hasara kar\u015f\u0131 koruyucu aktivitesini test etti.<\/p>\n
Bu makalede, kaba dall\u0131 alt\u0131n \u015feftalinin toprak \u00fcst\u00fc k\u0131sm\u0131n\u0131n etanol \u00f6z\u00fct\u00fc \u00fczerinde bir kimyasal bile\u015fim \u00e7al\u0131\u015fmas\u0131 yap\u0131lm\u0131\u015ft\u0131r. Toplam 10 phloroglucinol bile\u015fi\u011fi izole edilmi\u015f ve tan\u0131mlanm\u0131\u015ft\u0131r, bunlar\u0131n aras\u0131nda bile\u015fik 1 yeni bir bile\u015fiktir. Her bir bile\u015fi\u011fin n\u00f6roprotektif aktivitesi test edilmi\u015f ve 5 ve 6 numaral\u0131 bile\u015fiklerin 10 \u03bcM konsantrasyonda glutamat kaynakl\u0131 n\u00f6ronal hasar \u00fczerinde belirli bir koruyucu etkiye sahip oldu\u011fu bulunmu\u015ftur. 5 numaral\u0131 bile\u015fik pozitif kontrol resveratrol ile ayn\u0131 aktiviteye sahipti. Buna ek olarak, phloroglucinol bile\u015fikleri \u00e7o\u011funlukla \u00e7oklu kiral merkezlere sahip renksiz ya\u011fl\u0131 bile\u015fiklerdir, bu da klasik X-\u0131\u015f\u0131n\u0131 tek kristal k\u0131r\u0131n\u0131m deneyleri kullan\u0131larak mutlak konfig\u00fcrasyonlar\u0131n\u0131n belirlenmesini zorla\u015ft\u0131r\u0131r. Bununla birlikte, kar\u015f\u0131la\u015ft\u0131rmal\u0131 deneyler ve ECD spektrumlar\u0131n\u0131n hesaplanmas\u0131 yoluyla belirlenebilirler.<\/p>","protected":false},"excerpt":{"rendered":"
Study on the components of phloroglucinol in rough branch golden peach The plants of the Guttiferae family and the Hypericum genus are distributed throughout the country, especially in East China, West China, northern Sichuan, Guizhou, Xinjiang, and other areas where they are more concentrated. There are about 400 species worldwide, with 55 species and 8 […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\n