{"id":8037,"date":"2024-08-11T17:58:10","date_gmt":"2024-08-11T17:58:10","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=8037"},"modified":"2024-08-11T17:58:10","modified_gmt":"2024-08-11T17:58:10","slug":"fenfangji-root","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/fenfangji-root\/","title":{"rendered":"Fenfangji K\u00f6k\u00fcn\u00fcn Kimyasal Bile\u015fimi ve Anti Karaci\u011fer Fibrozis Aktivitesi \u00dczerine \u00c7al\u0131\u015fma"},"content":{"rendered":"<p>Fenfangji K\u00f6k\u00fcn\u00fcn Kimyasal Bile\u015fimi ve Anti Karaci\u011fer Fibrozis Aktivitesi \u00dczerine \u00c7al\u0131\u015fma<br \/>\nStephania tetrandra S. Moore, Menispermaceae familyas\u0131ndan, \u00e7o\u011funlukla Jiangxi, g\u00fcney Anhui, Zhejiang, Fujian ve di\u011fer b\u00f6lgelerde da\u011f\u0131l\u0131m g\u00f6steren bir bitki t\u00fcr\u00fcd\u00fcr. Kuru k\u00f6kleri ila\u00e7 olarak kullan\u0131ld\u0131\u011f\u0131nda, r\u00fczgar\u0131 da\u011f\u0131tma, a\u011fr\u0131y\u0131 hafifletme, di\u00fcrezi te\u015fvik etme ve \u015fi\u015fli\u011fi azaltma etkilerine sahiptir. Romatizma, romatizma, atlet aya\u011f\u0131, idrar yapma zorlu\u011fu ve egzama tedavisinde kullan\u0131l\u0131r. \u00d6nceki \u00e7al\u0131\u015fmalar Fenfangji'nin esas olarak bisbenzylisoquinoline, protoberberine, aporphine, protoaporphine ve phenanthrene gibi \u00e7e\u015fitli yap\u0131sal tipler de dahil olmak \u00fczere alkaloidler i\u00e7erdi\u011fini g\u00f6stermi\u015ftir. Modern farmakolojik ara\u015ft\u0131rmalar Fen Fang Ji ve Fen Fang Ji alkali'nin anti-t\u00fcm\u00f6r, anti-enflamatuar ve analjezik, anti karaci\u011fer fibrozu, kardiyovask\u00fcler sistem korumas\u0131, antibakteriyel ve anti hipertansif y\u00f6nlerden \u00f6nemli biyolojik aktivitelere sahip oldu\u011funu g\u00f6stermi\u015ftir. Fenfangji'deki di\u011fer aktif bile\u015fenleri daha fazla ara\u015ft\u0131rmak i\u00e7in, bu \u00e7al\u0131\u015fma Fenfangji k\u00f6k\u00fcn\u00fcn kimyasal bile\u015fimini sistematik olarak incelemi\u015f ve elde edilen bile\u015fiklerin hepatik stellat h\u00fccreleri LX-2'nin TGF - \u03b2 1 ile ind\u00fcklenen proliferasyonu \u00fczerindeki etkisini ara\u015ft\u0131rm\u0131\u015ft\u0131r. Ara\u015ft\u0131rma sonu\u00e7lar\u0131, Fenfangji'nin karaci\u011fer fibrozuna kar\u015f\u0131 farmakolojik maddelerini ayd\u0131nlatacak ve anti fibrotik ila\u00e7lar\u0131n geli\u015ftirilmesi i\u00e7in referans sa\u011flayacakt\u0131r.<\/p>\n<p>&nbsp;<\/p>\n<p>Bu \u00e7al\u0131\u015fmada, Fenfangji'den berberin (1), benzilizokinolin (2), izokinolin (4-6), pirol (3) ve piridin (7) gibi yap\u0131sal tiplere sahip 7 alkaloid dahil olmak \u00fczere 13 bile\u015fik izole edilmi\u015f ve tan\u0131mlanm\u0131\u015ft\u0131r. Bile\u015fik 1-13 ilk kez bu bitkiden izole edilmi\u015ftir ve bile\u015fik 3, 4, 6-9 Gentiana cinsinde rapor edilmemi\u015ftir. \u00d6nceki ara\u015ft\u0131rmalar Fenfangji'deki bile\u015fenlerin \u00f6nemli anti karaci\u011fer fibrozis etkileri oldu\u011funu bulmu\u015f ve izole edilen bile\u015fiklerin anti karaci\u011fer fibrozis aktivitesi de\u011ferlendirilmi\u015ftir. Bile\u015fiklerin TGF - \u03b2 1 ile ind\u00fcklenen LX-2 h\u00fccre proliferasyonu \u00fczerindeki etkisi tespit edilerek, bile\u015fiklerin anti karaci\u011fer fibroz aktivitesi \u00f6n olarak belirlenmi\u015ftir. Sonu\u00e7lar, alt\u0131 bile\u015fi\u011fin (2, 5, 6, 10-12) LX-2 h\u00fccre proliferasyonu \u00fczerinde \u00f6nemli inhibit\u00f6r etkilere sahip oldu\u011funu g\u00f6stermi\u015ftir. Bu \u00e7al\u0131\u015fman\u0131n sonu\u00e7lar\u0131, Fenfangji'nin anti karaci\u011fer fibrozundaki farmakolojik maddelerini daha da ayd\u0131nlatacak ve ayn\u0131 zamanda anti karaci\u011fer fibrozunda \u00f6nc\u00fc bile\u015fiklerin taranmas\u0131 i\u00e7in referans sa\u011flayacakt\u0131r.<\/p>","protected":false},"excerpt":{"rendered":"<p>Study on the Chemical Composition and Anti Liver Fibrosis Activity of Fenfangji Root Stephania tetrandra S. Moore is a plant species in the family Menispermaceae, mainly distributed in Jiangxi, southern Anhui, Zhejiang, Fujian and other regions. Using its dry roots as medicine, it has the effects of dispelling wind, relieving pain, promoting diuresis, and reducing [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Study on the Chemical Composition and Anti Liver Fibrosis Activity of Fenfangji Root - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/fenfangji-root\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study on the Chemical Composition and Anti Liver Fibrosis Activity of Fenfangji Root - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Study on the Chemical Composition and Anti Liver Fibrosis Activity of Fenfangji Root Stephania tetrandra S. Moore is a plant species in the family Menispermaceae, mainly distributed in Jiangxi, southern Anhui, Zhejiang, Fujian and other regions. 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Moore is a plant species in the family Menispermaceae, mainly distributed in Jiangxi, southern Anhui, Zhejiang, Fujian and other regions. 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