{"id":7903,"date":"2024-08-11T09:42:58","date_gmt":"2024-08-11T09:42:58","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=7903"},"modified":"2024-08-11T09:42:58","modified_gmt":"2024-08-11T09:42:58","slug":"artemisia-annua","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/artemisia-annua\/","title":{"rendered":"Artemisia annua'dan Toplam Flavonoidlerin Ekstraksiyonu, Safla\u015ft\u0131r\u0131lmas\u0131 ve Antioksidan Aktivite Analizi"},"content":{"rendered":"<p>Artemisia annua'dan Toplam Flavonoidlerin Ekstraksiyonu, Safla\u015ft\u0131r\u0131lmas\u0131 ve Antioksidan Aktivite Analizi<br \/>\nArtemisia japonica Thunb. \u00c7in'in bir\u00e7ok yerinde Asteraceae familyas\u0131ndan yayg\u0131n bir Artemisia t\u00fcr\u00fcd\u00fcr. G\u00fczel kokulu aromas\u0131 olan \u00e7ok y\u0131ll\u0131k bir bitkidir ve t\u0131bbi ve yenilebilir bir bitkidir. \u0130hale saplar\u0131 ve yapraklar\u0131 yenilebilir ve harika bir tada sahiptir. Artemisia annua, serin bir do\u011faya sahip, ac\u0131 ve hafif tatl\u0131 bir tada sahiptir ve t\u0131bbi ama\u00e7lar i\u00e7in b\u00fct\u00fcn bir bitki olarak kullan\u0131labilir; \u0131s\u0131y\u0131 temizleme, kan\u0131 so\u011futma ve detoksifiye etme etkilerine sahiptir. Modern farmakolojik ara\u015ft\u0131rmalar, Artemisia annua'n\u0131n anti-enflamatuar, antioksidan ve ya\u015flanma kar\u015f\u0131t\u0131 etkiler gibi \u00e7e\u015fitli sa\u011fl\u0131k yararlar\u0131 olan flavonoidler, polisakkaritler, polifenoller, saponinler ve u\u00e7ucu ya\u011flar gibi bol miktarda bile\u015fik i\u00e7erdi\u011fini g\u00f6stermi\u015ftir. Artemisia annua'da bulunan terpenler, alkaloidler, flavonoidler, steroidler, fenoller, benzersiz amino asitler ve polisakkaritler insektisidal, antibakteriyel ve bakterisidal aktivitelere sahiptir ve bitki bazl\u0131 insektisitler geli\u015ftirmek i\u00e7in kullan\u0131labilir.<\/p>\n<p>Flavonoidler, karbonil gruplar\u0131na sahip bir do\u011fal organik \u00fcr\u00fcn s\u0131n\u0131f\u0131d\u0131r ve \u00e7o\u011funlukla renkli olduklar\u0131 i\u00e7in flavonoidler olarak adland\u0131r\u0131l\u0131rlar. Bitkilerdeki ikincil metabolitlerin \u00f6nemli bir s\u0131n\u0131f\u0131 olan flavonoidler, \u00f6nemli fizyolojik ve farmakolojik etkilere sahiptir. Do\u011fada Asteraceae, Leguminosae ve Lamiaceae gibi dikotiledon bitkiler genellikle daha fazla flavonoid i\u00e7erir. Asteraceae familyas\u0131ndaki Artemisia cinsinin bir bitkisi olan Artemisia annua, flavonoidler a\u00e7\u0131s\u0131ndan \u00f6zellikle zengindir.<\/p>\n<p>G\u00fcn\u00fcm\u00fczde Artemisia annua, t\u00fcketim i\u00e7in bir sebze olarak veya geleneksel \u00c7in t\u0131bb\u0131 klinik form\u00fcllerinde \u015fifal\u0131 bir bitki olarak yayg\u0131n bir \u015fekilde kullan\u0131lmaktad\u0131r. Artemisia annua'n\u0131n modern t\u0131p ve sa\u011fl\u0131k alan\u0131ndaki t\u0131bbi kaynaklar\u0131n\u0131n geli\u015fimi hala d\u00fc\u015f\u00fck seviyededir ve Artemisia annua'n\u0131n toplam flavonoidleri hakk\u0131nda yurti\u00e7i ve yurtd\u0131\u015f\u0131nda \u00e7ok az ara\u015ft\u0131rma raporu bulunmaktad\u0131r. Gu ve arkada\u015flar\u0131 Artemisia scoparia'n\u0131n kimyasal bile\u015fimini analiz etmi\u015f ve ana flavonoidleri Artemisia scoparia, 8,4 '- dihidroksi-3,7,2' - trimetoksiflavon, 3,5-dihidroksi-6,7,3', 4' - tetrametoksiflavon, vb. olarak tan\u0131mlam\u0131\u015ft\u0131r; Zhang ve ark. Artemisia annua'daki toplam flavonoidlerin ekstraksiyon y\u00f6ntemini incelemi\u015f ve Artemisia annua'daki en y\u00fcksek toplam flavonoid veriminin 2 saat boyunca 85% metanol \u00e7\u00f6zeltisi ile Soxhlet ekstraksiyonu ile elde edildi\u011fini, verimin ise 6 saat boyunca 70% etanol \u00e7\u00f6zeltisi ile ekstraksiyonla daha d\u00fc\u015f\u00fck oldu\u011funu, ancak end\u00fcstriyel \u00fcretim i\u00e7in en uygun oldu\u011funu bulmu\u015ftur. Artemisia annua'dan toplam flavonoidlerin ekstraksiyonu, safla\u015ft\u0131rma s\u00fcreci optimizasyonu ve antioksidan aktivitesi hakk\u0131nda herhangi bir rapor bulunmamaktad\u0131r.<\/p>\n<p>Buna dayanarak, bu \u00e7al\u0131\u015fmada Artemisia annua'n\u0131n toprak \u00fcst\u00fc saplar\u0131 ve yapraklar\u0131 deneysel materyal olarak kullan\u0131lm\u0131\u015f, yan\u0131t y\u00fczey metodolojisi kullan\u0131larak Artemisia annua toplam flavonoidlerinin etanol ekstraksiyon s\u00fcreci optimize edilmi\u015f ve bu temelde Artemisia annua toplam flavonoidlerinin makro g\u00f6zenekli re\u00e7ine ile safla\u015ft\u0131rma ko\u015fullar\u0131 ara\u015ft\u0131r\u0131lm\u0131\u015ft\u0131r. Artemisia annua toplam flavonoidlerinin antioksidan aktivitesi, Artemisia annua'n\u0131n t\u0131p, sa\u011fl\u0131k ve g\u0131da alanlar\u0131nda geli\u015ftirilmesi ve uygulanmas\u0131 i\u00e7in teorik temel ve veri referans\u0131 sa\u011flamak amac\u0131yla analiz edilmi\u015ftir.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7904\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-335.png\" alt=\"\" width=\"659\" height=\"179\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7905\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-281.png\" alt=\"\" width=\"327\" height=\"189\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-281.png 327w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-281-325x189.png 325w\" sizes=\"(max-width: 327px) 100vw, 327px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full 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decoding=\"async\" class=\"alignnone size-full wp-image-7911\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-163.png\" alt=\"\" width=\"663\" height=\"442\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-163.png 663w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-163-650x433.png 650w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-163-325x217.png 325w\" sizes=\"(max-width: 663px) 100vw, 663px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7912\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-148.png\" alt=\"\" width=\"657\" height=\"895\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-148.png 657w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-148-529x720.png 529w\" sizes=\"(max-width: 657px) 100vw, 657px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7913\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-118.png\" alt=\"\" width=\"330\" height=\"173\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7914\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/11-111.png\" alt=\"\" width=\"321\" height=\"354\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7915\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/12-7.jpg\" alt=\"\" width=\"326\" height=\"184\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7916\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/13-5.jpg\" alt=\"\" width=\"326\" height=\"205\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7917\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/14-60.png\" alt=\"\" width=\"321\" height=\"177\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7918\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/15-43.png\" alt=\"\" width=\"322\" height=\"192\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7919\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/16-31.png\" alt=\"\" width=\"328\" height=\"185\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7920\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/17-24.png\" alt=\"\" width=\"336\" height=\"196\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7921\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/18-17.png\" alt=\"\" width=\"327\" height=\"179\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/18-17.png 327w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/18-17-325x179.png 325w\" sizes=\"(max-width: 327px) 100vw, 327px\" \/><br \/>\nBu \u00e7al\u0131\u015fmada, Anhui Eyaleti, Feixi \u0130l\u00e7esinden toplanan Artemisia annua'n\u0131n toprak \u00fcst\u00fc k\u0131s\u0131mlar\u0131 materyal olarak kullan\u0131lm\u0131\u015f ve yan\u0131t y\u00fczey metodolojisi kullan\u0131larak Artemisia annua'n\u0131n toplam flavonoid ekstraksiyon i\u00e7eri\u011fi \u00fczerinde etanol hacim fraksiyonu, ekstraksiyon s\u0131cakl\u0131\u011f\u0131, s\u0131v\u0131\/madde oran\u0131 ve ekstraksiyon s\u00fcresinin etkileri analiz edilmi\u015ftir. Artemisia annua toplam flavonoidlerinin etanol ekstraksiyonu i\u00e7in en uygun i\u015flem ko\u015fullar\u0131 70% etanol hacim oran\u0131, 20 mL etanol dozu, 85 dakika ekstraksiyon s\u00fcresi ve 40 \u2103 ekstraksiyon s\u0131cakl\u0131\u011f\u0131 olarak belirlenmi\u015ftir. Geleneksel etanol ekstraksiyon y\u00f6ntemi ile kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda, bu deneyde elde edilen optimum ekstraksiyon i\u015flemi ko\u015fullar\u0131, ekstraksiyon s\u00fcresini belirli bir \u00f6l\u00e7\u00fcde k\u0131saltm\u0131\u015f, uzun s\u00fcreli ekstraksiyonun aktif bile\u015fenler \u00fczerindeki etkisini \u00f6nlemi\u015f ve Artemisia annua'daki toplam flavonoidlerin ekstraksiyon miktar\u0131n\u0131 ve verimlili\u011fini art\u0131rm\u0131\u015ft\u0131r.<\/p>\n<p>Makrog\u00f6zenekli re\u00e7inenin Artemisia annua'daki toplam flavonoidler \u00fczerindeki safla\u015ft\u0131rma etkisi \u00fczerine yap\u0131lan deney, AB-8'in s\u0131ras\u0131yla 74.36% ve 85.32%'lik y\u00fcksek adsorpsiyon ve desorpsiyon oranlar\u0131na sahip oldu\u011funu ve Artemisia annua'daki toplam flavonoidlerin adsorpsiyonu ve ayr\u0131lmas\u0131 i\u00e7in ideal bir makrog\u00f6zenekli re\u00e7ine oldu\u011funu ortaya koymu\u015ftur. Safla\u015ft\u0131rma i\u015flemi s\u0131ras\u0131nda, Artemisia annua'daki toplam flavonoidler i\u00e7in AB-8 re\u00e7inesinin statik adsorpsiyon s\u00fcresinin 65.47% statik adsorpsiyon oran\u0131 ile 2 saatte kontrol edilmesi tavsiye edilir; Artemisia annua'dan toplam flavonoidlerin statik desorpsiyonu i\u00e7in en uygun s\u00fcre 1.74.63% statik desorpsiyon oran\u0131 ile 5 saat; AB-8 re\u00e7inesinin statik adsorpsiyonu i\u00e7in en uygun konsantrasyon Artemisia annua'n\u0131n toplam flavonoid ekstresi i\u00e7in 1.2mg\/mL; AB-8 re\u00e7inesinin statik desorpsiyonu i\u00e7in en uygun konsantrasyon 50% etanol konsantrasyonudur.<\/p>\n<p>A\u015f\u0131r\u0131 serbest radikaller, biyofilm lipidlerine potansiyel olarak zarar vererek, doku hasar\u0131na neden olarak ve \u00e7e\u015fitli hastal\u0131klar\u0131n ortaya \u00e7\u0131kmas\u0131na yol a\u00e7arak insan sa\u011fl\u0131\u011f\u0131n\u0131 ciddi \u015fekilde etkiler. Serbest radikallerin insan v\u00fccuduna verdi\u011fi zarar\u0131n azalt\u0131lmas\u0131 b\u00fcy\u00fck bir ara\u015ft\u0131rma \u00f6nemine sahiptir. Flavonoidler serbest radikalleri temizleme yetene\u011fine sahiptir. Deneyde, Artemisia annua'daki toplam flavonoidlerin antioksidan aktivitesini analiz etmek i\u00e7in indirgeme g\u00fcc\u00fc ve ABTS+-, DPPH -, - OH, O2- - serbest radikallerini temizleme gibi g\u00f6stergeler se\u00e7ilmi\u015ftir. Sonu\u00e7lar, Artemisia annua'daki toplam flavonoidlerin g\u00fc\u00e7l\u00fc indirgeme g\u00fcc\u00fcne sahip oldu\u011funu ve ABTS+-, DPPH-, - OH ve O2- - i\u00e7in doz etkisi g\u00f6steren iyi bir s\u00fcp\u00fcrme yetene\u011fi sergiledi\u011fini g\u00f6stermi\u015ftir. Safla\u015ft\u0131rmadan sonra, Artemisia annua'daki toplam flavonoidlerin antioksidan aktivitesi artm\u0131\u015ft\u0131r. Artemisia annua'n\u0131n toplam flavonoidleri, bitki flavonoid kaynaklar\u0131 olarak potansiyel ve uygulama de\u011ferine sahiptir ve derinlemesine ara\u015ft\u0131rma i\u00e7in do\u011fal bir antioksidan olarak kullan\u0131labilir ve Artemisia annua toplam flavonoidlerinin daha da geli\u015ftirilmesi ve uygulanmas\u0131 i\u00e7in teorik bir temel sa\u011flar.<\/p>","protected":false},"excerpt":{"rendered":"<p>Extraction, Purification, and Antioxidant Activity Analysis of Total Flavonoids from Artemisia annua Artemisia japonica Thunb. is a common species of Artemisia in the Asteraceae family in many parts of China. It is a perennial herb with a fragrant aroma and is a medicinal and edible plant. Its tender stems and leaves are edible and have [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Extraction, Purification, and Antioxidant Activity Analysis of Total Flavonoids from Artemisia annua - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/artemisia-annua\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Extraction, Purification, and Antioxidant Activity Analysis of Total Flavonoids from Artemisia annua - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Extraction, Purification, and Antioxidant Activity Analysis of Total Flavonoids from Artemisia annua Artemisia japonica Thunb. is a common species of Artemisia in the Asteraceae family in many parts of China. 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It is a perennial herb with a fragrant aroma and is a medicinal and edible plant. 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