{"id":6070,"date":"2024-08-05T16:39:55","date_gmt":"2024-08-05T16:39:55","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=6070"},"modified":"2024-08-05T16:39:55","modified_gmt":"2024-08-05T16:39:55","slug":"blood-pressure-reducing-medicinal-food-ingredients","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/blood-pressure-reducing-medicinal-food-ingredients\/","title":{"rendered":"Kan bas\u0131nc\u0131n\u0131 d\u00fc\u015f\u00fcren 10 t\u0131bbi bile\u015fenle ilgili ara\u015ft\u0131rmalar\u0131n ilerleyi\u015fi ve g\u00f6r\u00fcn\u00fcm\u00fc nedir?"},"content":{"rendered":"

2017 y\u0131l\u0131nda \u00c7in, Ayn\u0131 Kaynaktan Gelen \u0130la\u00e7 ve G\u0131da Hammaddeleri Katalo\u011fu'nu yay\u0131nlad\u0131 ve CA, BA, Springer, CNKI ve Wipro veritabanlar\u0131nda yap\u0131lan literat\u00fcr taramas\u0131n\u0131n ard\u0131ndan baz\u0131 bulgulara ula\u015ft\u0131k Lysimachia officinalis, Hawthorn, Chrysanthemum, Pueraria lobata, Cassia tohumu, Oyster, Papaya, Forsythia, Ceviz \u00e7ekirde\u011fi ve Kombucha gibi tansiyon d\u00fc\u015f\u00fcr\u00fcc\u00fc etkisi olan ila\u00e7lar ve yiyecekler.<\/strong><\/p>\n

G\u0131da terapisi, organizmay\u0131 d\u00fczenleme, hastal\u0131klar\u0131 ortaya \u00e7\u0131kmadan \u00f6nce \u00f6nleme ve hipertansif hastal\u0131klar\u0131n \u00f6nlenmesi ve tedavisi i\u00e7in yeni bir yol a\u00e7ma i\u015flevine sahiptir. Bu makalede, kan bas\u0131nc\u0131n\u0131 d\u00fc\u015f\u00fcren t\u0131bbi ve g\u0131da maddelerinin kan bas\u0131nc\u0131n\u0131 d\u00fc\u015f\u00fcrme mekanizmalar\u0131 ve g\u0131da<\/p>\n

t\u0131bbi g\u0131da ara\u015ft\u0131rmalar\u0131 ve uygulamalar\u0131 i\u00e7in referans sa\u011flamak amac\u0131yla ara\u015ft\u0131rma ilerlemesi.<\/p>\n

Rafflesia<\/strong><\/p>\n

Rafflesia, Cruciferae familyas\u0131ndaki turpun kurutulmu\u015f olgun tohumlar\u0131 olup, alkaloidler, tiyoglukozitler, izotiyosiyanatlar, flavonoidler, u\u00e7ucu ya\u011flar, ya\u011fl\u0131 ya\u011flar, proteinler, polisakkaritler ve di\u011fer kimyasal bile\u015fimleri i\u00e7erir ve bunlardan erusik asit tiyosiyanat kan bas\u0131nc\u0131n\u0131 d\u00fc\u015f\u00fcrmede aktif bile\u015fendir.<\/p>\n

Li Tieyun, spontan hipertansif s\u0131\u00e7anlar\u0131n kan bas\u0131nc\u0131n\u0131 \u00f6nemli \u00f6l\u00e7\u00fcde d\u00fc\u015f\u00fcrme etkisine sahip olan Rafflesia'n\u0131n suda \u00e7\u00f6z\u00fcn\u00fcr alkaloidlerini almas\u0131na izin verdi ve antihipertansif etkisi nitrik oksit-kardiyo-nitrik oksit sentaz sistemini aktive edebilir, b\u00f6ylece kan damarlar\u0131n\u0131n vazodilatasyonu, kan bas\u0131nc\u0131 d\u00fc\u015fer ve antioksidan etkiler yoluyla hedef organlar\u0131 koruyabilir ve hasar\u0131 azaltabilir.<\/p>\n

Gong Jirong, hastalar\u0131n Lycopodium album i\u00e7eren kaps\u00fcl\u00fc 3 haftadan uzun bir s\u00fcre boyunca a\u011f\u0131zdan almas\u0131na izin verdi ve toplam antihipertansif etkinlik oran\u0131 87.5% oldu, bu da Lycopodium album'\u00fcn etkili bir antihipertansif ila\u00e7 oldu\u011funu kan\u0131tlad\u0131.<\/p>\n

Al\u0131\u00e7<\/strong><\/p>\n

Al\u0131\u00e7 meyve \u00f6z\u00fct\u00fcn\u00fcn kimyasal bile\u015fimi esas olarak kan lipitlerini d\u00fc\u015f\u00fcrme, miyokardiyal kas\u0131lmay\u0131 te\u015fvik etme ve miyokard\u0131 koruma, anti-ateroskleroz ve kan bas\u0131nc\u0131n\u0131 d\u00fc\u015f\u00fcrme etkilerine sahip flavonoidler ve triterpenoidlerdir.<\/p>\n

Etki mekanizmas\u0131, endotel ba\u011f\u0131ml\u0131 damar geni\u015fletici maddeleri d\u00fczenleyerek periferik damar direncini azaltmak ve antioksidan etkiler yoluyla \u00f6nemli doku ve organlarda hipertansiyon kaynakl\u0131 hasar\u0131 korumakt\u0131r.<\/p>\n

Yuan Yuan ve arkada\u015flar\u0131, hiperlipidemi modeli s\u0131\u00e7anlarla birlikte renal hipertansiyon olu\u015fturdular ve onlara al\u0131\u00e7 \u00f6z\u00fct\u00fc verdiler, istikrarl\u0131 ve uzun s\u00fcreli lipit d\u00fczenleyici etkiye sahiptir, bu arada kan bas\u0131nc\u0131n\u0131n tekrar y\u00fckselmemesini kontrol edebilir ve antihipertansif mekanizmas\u0131 periferik kan damarlar\u0131n\u0131n geni\u015flemesine dayan\u0131r.<\/p>\n

Krizantem<\/strong><\/p>\n

Krizantem, Asteraceae familyas\u0131ndan Aster cinsinin \u00e7i\u00e7ek tomurcu\u011fu veya \u00e7i\u00e7e\u011fidir. Krizantem ekstrakt\u0131n\u0131n ana kimyasal bile\u015fenleri flavonoidler, triterpenoidler ve u\u00e7ucu ya\u011fd\u0131r.<\/p>\n

Modern farmakolojik \u00e7al\u0131\u015fmalar, Krizantem'in koroner arterleri, diyastolik kan damarlar\u0131n\u0131 geni\u015fletme, koroner kan ak\u0131\u015f\u0131n\u0131 art\u0131rma, kan bas\u0131nc\u0131n\u0131 d\u00fc\u015f\u00fcrme, antioksidan, kalp canl\u0131l\u0131\u011f\u0131n\u0131 art\u0131rma, kardiyotonik ve anti-aritmik etkiler gibi \u00f6nemli etkileri oldu\u011funu g\u00f6stermi\u015ftir.<\/p>\n

Pueraria Mirifica<\/strong><\/p>\n

Pueraria Mirifica'n\u0131n ana bile\u015fenleri aras\u0131nda izoflavonlar, puerarin, triterpenoid saponinler, alkaloidler ve di\u011fer bile\u015fikler bulunur. \u0130zoflavonlar\u0131, damar geni\u015fletici, kan bas\u0131nc\u0131n\u0131 d\u00fc\u015f\u00fcr\u00fcc\u00fc, anti-miyokardiyal iskemi ve benzeri etkiye sahip Puerarin i\u00e7erir.<\/p>\n

Sun Yunxiang ve arkada\u015flar\u0131n\u0131n \u00e7al\u0131\u015fmas\u0131 Puerarin'in vazodilat\u00f6r etkiye sahip oldu\u011funu do\u011frulam\u0131\u015ft\u0131r; ve L-nitroarginin uygulamas\u0131nda vazodilat\u00f6r etkisinin ve endotel h\u00fccrelerinin tahribat\u0131n\u0131n \u00f6nemli \u00f6l\u00e7\u00fcde zay\u0131flad\u0131\u011f\u0131n\u0131 bulmu\u015ftur, bu da vask\u00fcler endotel h\u00fccreleri taraf\u0131ndan sentezlenen NO'nun Puerarin'in vazodilat\u00f6r etkisinde rol oynayabilece\u011fini d\u00fc\u015f\u00fcnd\u00fcrmektedir.<\/p>\n

Sinameki tohumu<\/strong><\/p>\n

Cassia tohumu bir baklagil cassia veya k\u00fc\u00e7\u00fck cassia olgun kuru tohumlar, antrakinonlar i\u00e7in ana kimyasal bile\u015fenleri, ba\u015fka bir protein, polisakkarit ve \u00e7e\u015fitli temel amino asitler ve eser elementler cassia tohumu \u00f6z\u00fc vazodilat\u00f6rd\u00fcr. Etki, kalsiyum kanal\u0131 a\u00e7\u0131lmas\u0131n\u0131n resept\u00f6r manip\u00fclasyonunun inhibisyonu, vask\u00fcler endotelyal h\u00fccrelerin iNOS ve nitrik oksit sal\u0131n\u0131m\u0131n\u0131n d\u00fczenlenmesi ile ilgili olabilir.<\/p>\n

Yu Hairong ve arkada\u015flar\u0131, renal hipertansiyonlu s\u0131\u00e7anlara gavajla cassia tohumu antrakinon glikozidi vererek, bu y\u00f6ntemin hipertansiyon kaynakl\u0131 b\u00f6brek hasar\u0131n\u0131 iyile\u015ftirmek i\u00e7in s\u0131\u00e7anlar\u0131n kaudal arterinin sistolik kan bas\u0131nc\u0131n\u0131, idrar alb\u00fcmini ve \u03b22-mikroglobulin i\u00e7eri\u011fini \u00f6nemli \u00f6l\u00e7\u00fcde azaltabilece\u011fini ve etki mekanizmas\u0131n\u0131n intrakardiyak anjiyotensin \u2161, aldosteron ve endotelin sekresyonunun inhibisyonu ile ili\u015fkili olabilece\u011fini bulmu\u015flard\u0131r.<\/p>\n

\u0130stiridye<\/strong><\/p>\n

\u0130stiridye amino asitler, polisakkaritler, B vitaminleri, taurin, kalsiyum, fosfor, demir ve \u00e7inko i\u00e7erir. Shao Jiangjuan ve arkada\u015flar\u0131, istiridyenin Pueraria lobata'n\u0131n kan bas\u0131nc\u0131n\u0131 d\u00fc\u015f\u00fcrme \u00fczerinde sinerjik bir etkiye sahip oldu\u011funu ve mekanizmas\u0131n\u0131n renin-anjiyotensin-aldosteron sisteminin inhibisyonu, vask\u00fcler endotel fonksiyonunun iyile\u015ftirilmesi ve aort d\u00fcz kas h\u00fccrelerinde \u00e7e\u015fitli sinyal yollar\u0131 taraf\u0131ndan tetiklenen h\u00fccre i\u00e7i kalsiyum iyonlar\u0131n\u0131n blokaj\u0131 ile ili\u015fkili oldu\u011funu bulmu\u015flard\u0131r.<\/p>\n

Papaya<\/strong><\/p>\n

Papaya, papaya ailesinin otsu bitkisinin meyvesidir ve bile\u015fiminde organik asitler, flavonoidler, papain ve polisakkaritler bulunur. Liu Saisai ve arkada\u015flar\u0131 kazeini papain ile hidrolize ederek tansiyon d\u00fc\u015f\u00fcr\u00fcc\u00fc peptitler haz\u0131rlam\u0131\u015flard\u0131r. Hipotansif peptidler olarak da bilinen anjiyotensin d\u00f6n\u00fc\u015ft\u00fcr\u00fcc\u00fc enzim inhibit\u00f6rleri, \u00f6nemli kan bas\u0131nc\u0131 d\u00fc\u015f\u00fcr\u00fcc\u00fc etkileri olan bir peptid s\u0131n\u0131f\u0131d\u0131r.<\/p>\n

Forsythia<\/strong><\/p>\n

Forsythia, flavonoidler, u\u00e7ucu ya\u011flar, kumarinler, polisakkaritler ve di\u011fer kimyasal bile\u015fenler i\u00e7eren Citrus aurantium'un kurutulmu\u015f meyvesidir.<\/p>\n

Chang Wen ve arkada\u015flar\u0131, anjiyotensin d\u00f6n\u00fc\u015ft\u00fcr\u00fcc\u00fc enzimin Forsythia'n\u0131n farkl\u0131 \u00e7\u00f6z\u00fcc\u00fc \u00f6z\u00fctleri taraf\u0131ndan inhibisyonunu HPLC y\u00f6ntemiyle kar\u015f\u0131la\u015ft\u0131rm\u0131\u015f ve en iyi inhibisyon etkisine sahip aktif k\u0131sm\u0131 bulmu\u015f ve Forsythia'n\u0131n hipotansif etkisinin esas olarak renin-anjiyotensin-aldosteron sistemiyle ilgili olabilece\u011fini tahmin etmi\u015flerdir.<\/p>\n

Ceviz \u0130\u00e7i<\/strong><\/p>\n

Ceviz i\u00e7i, y\u00fcksek kaliteli ya\u011f, protein, amino asitler, karbonhidratlar ve fosfor, kalsiyum, demir, potasyum ve B, C ve E vitaminleri gibi mineral elementler i\u00e7eren, besin a\u00e7\u0131s\u0131ndan zengin olan ceviz, Walnutaceae'nin tohum \u00e7ekirde\u011fidir.<\/p>\n

Xu Huijiao ve arkada\u015flar\u0131, protein ekstraksiyonu i\u00e7in hammadde olarak ya\u011fdan ar\u0131nd\u0131r\u0131lm\u0131\u015f ceviz unu, kan bas\u0131nc\u0131n\u0131 d\u00fc\u015f\u00fcrme aktivitesinin ceviz proteini hidroliz \u00fcr\u00fcn\u00fc \u00fczerinde be\u015f farkl\u0131 proteaz \u00e7al\u0131\u015fmas\u0131, sonu\u00e7lar \u015funu g\u00f6stermektedir: ceviz proteini enzimatik \u00fcr\u00fcnleri iyi bir anjiyotensin d\u00f6n\u00fc\u015ft\u00fcr\u00fcc\u00fc enzim inhibit\u00f6r etkisine sahiptir.<\/p>\n

Kombucha<\/strong><\/p>\n

Kombucha kan bas\u0131nc\u0131n\u0131 etkili bir \u015fekilde d\u00fc\u015f\u00fcrebilir. Li Xiangrong ve arkada\u015flar\u0131, kombuchan\u0131n spontan hipertansif s\u0131\u00e7anlara yedirilerek kan bas\u0131nc\u0131n\u0131 belirli bir \u00f6l\u00e7\u00fcde d\u00fc\u015f\u00fcrebilece\u011fini ve kombuchadaki lofanik asidin kan bas\u0131nc\u0131n\u0131 d\u00fc\u015f\u00fcrmede rol oynad\u0131\u011f\u0131n\u0131 g\u00f6stermi\u015ftir. Ren Dandan ve arkada\u015flar\u0131 daha ileri testler sonucunda Roburonik asit ve di\u011fer aktif bile\u015fenlerden olu\u015fan yosun \u00f6z\u00fct\u00fcn\u00fcn anjiyotensin d\u00f6n\u00fc\u015ft\u00fcr\u00fcc\u00fc enzimin aktivitesini etkili bir \u015fekilde inhibe ederek kan bas\u0131nc\u0131n\u0131 d\u00fc\u015f\u00fcrme etkisini elde edebildi\u011fi sonucuna varm\u0131\u015ft\u0131r.<\/p>","protected":false},"excerpt":{"rendered":"

In 2017, China published the Catalog of Raw Materials from the Same Source of Medicine and Food, and after literature search in CA, BA, Springer, CNKI and Wipro databases, we found some medicines and food with blood pressure-lowering effect, which are Lysimachia officinalis, Hawthorn, Chrysanthemum, Pueraria lobata, Cassia seed, Oyster, Papaya, Forsythia, Walnut kernel and […]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[46],"tags":[],"yoast_head":"\nWhat is the progress and outlook of research on 10 blood pressure-lowering medicinal ingredients? - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/blood-pressure-reducing-medicinal-food-ingredients\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What is the progress and outlook of research on 10 blood pressure-lowering medicinal ingredients? 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