{"id":5744,"date":"2024-08-04T20:56:18","date_gmt":"2024-08-04T20:56:18","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5744"},"modified":"2024-08-04T20:56:18","modified_gmt":"2024-08-04T20:56:18","slug":"bp-ann-combined-with-critic-method","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/bp-ann-combined-with-critic-method\/","title":{"rendered":"Angelica sinensis kuyruk ekstraksiyon i\u015flemi parametrelerinin CRITIC y\u00f6ntemi ile birlikte BP-ANN'ye dayal\u0131 optimizasyonu"},"content":{"rendered":"

Angelica sinensis kuyruk ekstraksiyon i\u015flemi parametrelerinin CRITIC y\u00f6ntemi ile birlikte BP-ANN'ye dayal\u0131 optimizasyonu
\nAngelica sinensis (Oliv) Diels, Umbelliferae familyas\u0131ndan bir bitki olan Angelica sinensis (Oliv) Diels'in kurutulmu\u015f k\u00f6k\u00fcd\u00fcr. \"K\u00f6k dallanma teorisinin\" temsili bir \u015fifal\u0131 bitkisidir ve klinik uygulamada kan eksikli\u011fi, sararma, ba\u015f d\u00f6nmesi, \u00e7arp\u0131nt\u0131, adet bozukluklar\u0131, adet kramplar\u0131, so\u011fuk eksikli\u011fi, kar\u0131n a\u011fr\u0131s\u0131, romatizma, \u00f6dem, \u00fclser, ba\u011f\u0131rsak kurulu\u011fu ve kab\u0131zl\u0131k gibi durumlar\u0131 tedavi etmek i\u00e7in yayg\u0131n olarak kullan\u0131l\u0131r. Geleneksel \u00c7in t\u0131bb\u0131 uygulay\u0131c\u0131lar\u0131 Angelica sinensis'in farkl\u0131 t\u0131bbi k\u0131s\u0131mlar\u0131n\u0131n ayr\u0131 ayr\u0131 kullan\u0131lmas\u0131 gerekti\u011fine inanmaktad\u0131r. \u00d6rne\u011fin, \"Angelica sinensis ba\u015ftaki kanamay\u0131 durdurmal\u0131, v\u00fccuttaki kan\u0131 beslemeli, kuyruktaki kan\u0131 k\u0131rmal\u0131 ve v\u00fccuttaki kan dola\u015f\u0131m\u0131n\u0131 te\u015fvik etmelidir\" (Li Gao'nun \"Dalak ve Mide \u00dczerine\"). Proje ekibinin \u00f6n ara\u015ft\u0131rmas\u0131nda, Angelica sinensis'in farkl\u0131 t\u0131bbi k\u0131s\u0131mlar\u0131n\u0131n \u0131s\u0131tma ve geri ak\u0131\u015f ekstraksiyonundan (bundan sonra \"ekstraksiyon\" olarak an\u0131lacakt\u0131r) sonra, ferulik asit, klorojenik asit, Euphorbia ve ligustilide y\u00fczdesi i\u00e7eri\u011finin yan\u0131 s\u0131ra Angelica sinensis kuyru\u011funun kuru hamur oran\u0131n\u0131n t\u00fcm\u00fc, Angelica sinensis'in farkl\u0131 t\u0131bbi k\u0131s\u0131mlar\u0131 \u00fczerinde ayr\u0131 uygulama ve ara\u015ft\u0131rma ihtiyac\u0131n\u0131 g\u00f6steren bir azalma e\u011filimi g\u00f6stermi\u015ftir.
\nLiterat\u00fcr ara\u015ft\u0131rmas\u0131, Angelica sinensis \u00fczerine yap\u0131lan mevcut ara\u015ft\u0131rmalar\u0131n \u00e7o\u011funlukla Angelica sinensis'in genel \u00e7al\u0131\u015fmas\u0131na odakland\u0131\u011f\u0131n\u0131 ve Angelica sinensis'in belirli bir t\u0131bbi k\u0131sm\u0131 \u00fczerinde ara\u015ft\u0131rma eksikli\u011fi oldu\u011funu ortaya koymu\u015ftur; Ayr\u0131ca, klinik uygulama ve \u00fcretim prati\u011finde, ilgili \u00e7al\u0131\u015fmalar \u00e7o\u011funlukla Angelica sinensis'in t\u00fcm v\u00fccudu \u00fczerinde y\u00fcr\u00fct\u00fclmektedir ve eski y\u00f6ntemleri takip eden ve Angelica sinensis'in belirli bir t\u0131bbi k\u0131sm\u0131n\u0131 hedef alan \u00e7ok az vaka vard\u0131r; Zaman i\u00e7inde bu durum, geleneksel \u00c7in t\u0131bb\u0131ndaki \"miras ve yenilik\" geli\u015fim ilkelerine uygun olmad\u0131\u011f\u0131 gibi, Angelica sinensis \u00fczerine kapsaml\u0131 ve derinlemesine ara\u015ft\u0131rma yap\u0131lmas\u0131na da elveri\u015fli de\u011fildir. Bu nedenle, proje ekibi Angelica sinensis kuyru\u011funu ana ara\u015ft\u0131rma nesnesi olarak almay\u0131, ferulik asit dahil d\u00f6rt ana kimyasal bile\u015fenin y\u00fczde i\u00e7eri\u011fini ve Angelica sinensis kuyru\u011funun kuru hamur oran\u0131n\u0131 de\u011ferlendirme g\u00f6stergeleri olarak se\u00e7meyi, ekstraksiyon s\u0131kl\u0131\u011f\u0131n\u0131, kat\u0131-s\u0131v\u0131 oran\u0131n\u0131 ve ekstraksiyon s\u00fcresini de\u011ferlendirme fakt\u00f6rleri olarak se\u00e7meyi ve Angelica sinensis kuyru\u011funun ekstraksiyon s\u00fcrecini sistematik olarak incelemek i\u00e7in CRITIC y\u00f6ntemiyle birlikte BP-ANN kullanmay\u0131, Angelica sinensis kuyru\u011funun optimum ekstraksiyon s\u00fcrecini olu\u015fturmak ve Angelica sinensis kuyru\u011fu \u00fczerinde daha fazla ara\u015ft\u0131rma i\u00e7in veri deste\u011fi sa\u011flamak amac\u0131yla ilgili i\u015flem parametrelerini optimize etmeyi planlamaktad\u0131r.<\/p>\n

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De\u011ferlendirme g\u00f6stergelerinin se\u00e7imi. Literat\u00fcr ara\u015ft\u0131rmas\u0131, makalede bahsedilen ferulik asit, klorojenik asit ve ligustilidin Angelica sinensis ile ilgili mevcut ara\u015ft\u0131rmalarda en s\u0131k rastlanan kimyasal bile\u015fenler oldu\u011funu g\u00f6stermi\u015ftir; Ferulik asit, Farmakopede belirtildi\u011fi gibi Angelica sinensis'in bir g\u00f6sterge bile\u015fenidir ve ayr\u0131ca anti trombosit agregasyonu ve trombosit 5-hidroksitriptamin sal\u0131n\u0131m\u0131n\u0131n inhibisyonuna sahiptir; Klorojenik asit, Angelica sinensis'te \u00f6nemli bir fenolik asit bile\u015fenidir. Klinik \u00e7al\u0131\u015fmalar, sadece merkezi sinir sistemini uyarmakla kalmay\u0131p ayn\u0131 zamanda antiviral ve antibakteriyel \u00f6zelliklere de sahip oldu\u011funu g\u00f6stermi\u015ftir; Angelica sinensis'teki \u00f6nemli u\u00e7ucu ya\u011f aktif bile\u015fenlerinden biri olan Gaoben lakton, spazmlar\u0131 hafifletebilir, sakinle\u015ftirebilir ve ast\u0131m\u0131 tedavi edebilir; Eucommia ulmoides, Angelica sinensis'te \u00fcretim alan\u0131na ba\u011fl\u0131 olarak b\u00fcy\u00fck \u00f6l\u00e7\u00fcde de\u011fi\u015fen \u00f6nemli bir kumarin bile\u015fenidir, ancak Angelica sinensis'in bir g\u00f6sterge bile\u015feni olarak kullanan \u00e7ok az ilgili \u00e7al\u0131\u015fma vard\u0131r. \u00d6zetle, \u00f6nceki ara\u015ft\u0131rmalara dayanarak, d\u00f6rt kimyasal bile\u015fenin y\u00fczde i\u00e7eri\u011fini ve Angelica sinensis'in kuru hamur oran\u0131n\u0131 de\u011ferlendirme g\u00f6stergeleri olarak kullanmak, geleneksel \u00c7in t\u0131bb\u0131 klinik ila\u00e7 kanallar\u0131n\u0131n \u00f6zelliklerini, \u00e7oklu hedefleri ve karma\u015f\u0131k hastal\u0131k ilerleme seviyelerini kar\u015f\u0131larken, bu \u00e7al\u0131\u015fman\u0131n sonu\u00e7lar\u0131n\u0131 daha bilimsel ve do\u011fru hale getirebilir.
\nA\u011f\u0131rl\u0131k katsay\u0131s\u0131 hesaplama y\u00f6nteminin se\u00e7imi. Bilindi\u011fi gibi, geleneksel \u00c7in t\u0131bb\u0131n\u0131n farmakolojik bile\u015fenleri karma\u015f\u0131kt\u0131r ve \u00e7ok \u00e7e\u015fitli farmakolojik etkilere sahiptir. Bu nedenle, \u00e7oklu indeks bile\u015feni \u00e7al\u0131\u015fmalar\u0131 y\u00fcr\u00fct\u00fcrken, genellikle her bir indeks bile\u015feninin a\u011f\u0131rl\u0131k katsay\u0131lar\u0131n\u0131 netle\u015ftirmek gerekir. CRITIC y\u00f6ntemi, ilgili a\u011f\u0131rl\u0131klar\u0131 kapsaml\u0131 bir \u015fekilde \u00f6l\u00e7mek i\u00e7in de\u011ferlendirme g\u00f6stergelerinin standart sapmas\u0131n\u0131 ve korelasyon katsay\u0131s\u0131n\u0131 kullanan objektif bir a\u011f\u0131rl\u0131kland\u0131rma y\u00f6ntemidir. Elde edilen a\u011f\u0131rl\u0131k katsay\u0131lar\u0131 ara\u015ft\u0131rmac\u0131n\u0131n bilgi ve deneyimi gibi fakt\u00f6rlerden daha az etkilenir ve elde edilen ilgili a\u011f\u0131rl\u0131klar \u00f6znel a\u011f\u0131rl\u0131kland\u0131rma, AHP a\u011f\u0131rl\u0131kland\u0131rma ve di\u011fer a\u011f\u0131rl\u0131kland\u0131rma y\u00f6ntemlerine k\u0131yasla daha bilimsel ve titizdir.
\nBP-ANN, insan beyin dokusunun yap\u0131s\u0131n\u0131 ve \u00e7al\u0131\u015fma mekanizmas\u0131n\u0131 sim\u00fcle edebilen ak\u0131ll\u0131 bir sistemdir. Sadece kendi kendini organize etme, uyarlama ve kendi kendine \u00f6\u011frenme yeteneklerine sahip olmakla kalmaz, ayn\u0131 zamanda iyi bir fonksiyon yakla\u015f\u0131m\u0131 yetene\u011fine de sahiptir. BP-ANN, s\u0131n\u0131rl\u0131 bir aral\u0131kta optimum de\u011feri bulmak i\u00e7in daha iyi uydurma ve tahmin ger\u00e7ekle\u015ftirebilir. Ortogonal deneyler ve yan\u0131t y\u00fczeyleri gibi deneysel tasar\u0131m y\u00f6ntemleriyle kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda, s\u0131n\u0131rl\u0131 bir aral\u0131kta optimum ekstraksiyon i\u015flemi parametrelerini bulmay\u0131 otonom olarak \u00f6\u011frenebilir, elde edilen ko\u015fullar\u0131 daha do\u011fru hale getirirken deney say\u0131s\u0131n\u0131 azaltabilir; Ayn\u0131 zamanda geleneksel \u00c7in t\u0131bb\u0131 ekstraksiyonunun karma\u015f\u0131kl\u0131\u011f\u0131n\u0131 ve \u00e7e\u015fitlili\u011fini kar\u015f\u0131lar.
\n\u00d6zetle, bu deneyde Angelica sinensis kuyru\u011funun ekstraksiyon i\u015flemi parametrelerini optimize etmek i\u00e7in CRITIC y\u00f6ntemi ile birlikte BP-ANN kullan\u0131lm\u0131\u015ft\u0131r. Sonu\u00e7lar daha bilimsel, titiz ve do\u011frudur, bu da Angelica sinensis kuyru\u011funun sonraki sistematik ve sistematik ara\u015ft\u0131rmas\u0131 i\u00e7in veri deste\u011fi sa\u011flayabilir ve Angelica sinensis \u00fczerine daha derin ara\u015ft\u0131rmalar i\u00e7in yeni fikirler sa\u011flayabilir.<\/p>","protected":false},"excerpt":{"rendered":"

Optimization of Angelica sinensis tail extraction process parameters based on BP-ANN combined with CRITIC method Angelica sinensis (Oliv) Diels, a plant in the Umbelliferae family, is the dried root of Angelica sinensis (Oliv) Diels. It is a representative medicinal herb of the “root branching theory” and is commonly used in clinical practice to treat conditions […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nOptimization of Angelica sinensis tail extraction process parameters based on BP-ANN combined with CRITIC method - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/bp-ann-combined-with-critic-method\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Optimization of Angelica sinensis tail extraction process parameters based on BP-ANN combined with CRITIC method - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Optimization of Angelica sinensis tail extraction process parameters based on BP-ANN combined with CRITIC method Angelica sinensis (Oliv) Diels, a plant in the Umbelliferae family, is the dried root of Angelica sinensis (Oliv) Diels. 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