{"id":5682,"date":"2024-08-04T20:33:17","date_gmt":"2024-08-04T20:33:17","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5682"},"modified":"2024-08-04T20:33:17","modified_gmt":"2024-08-04T20:33:17","slug":"stinky-grass","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/kokusmus-cimen\/","title":{"rendered":"Koku\u015fmu\u015f \u00c7imdeki Diklorometan K\u0131sm\u0131n\u0131n Kimyasal Bile\u015fenleri \u00dczerine \u00c7al\u0131\u015fma"},"content":{"rendered":"<p>Koku\u015fmu\u015f \u00c7imdeki Diklorometan K\u0131sm\u0131n\u0131n Kimyasal Bile\u015fenleri \u00dczerine \u00c7al\u0131\u015fma<br \/>\nYuncao, Rutaceae familyas\u0131ndan Ruta graveolens L. bitkisinin tamam\u0131d\u0131r, g\u00fc\u00e7l\u00fc bir kokuya sahip \u00e7ok y\u0131ll\u0131k otsu bir bitkidir. Kokmu\u015f pelin otu (Guangxi Bitkisel T\u0131p), k\u00fc\u00e7\u00fck ot (Guangxi Bitki Listesi) ve kedi nanesi yedi (Guangxi Bitkisel T\u0131p) olarak da bilinir. Yaz aylar\u0131nda toplan\u0131r, g\u00f6lgede kurutulur, bitkinin tamam\u0131 ila\u00e7 olarak kullan\u0131labilir ve dallar\u0131 ve yapraklar\u0131 t\u00fcketim i\u00e7in pi\u015firilebilir (\"Compendium of Materia Medica\"). Do\u011fas\u0131 gere\u011fi so\u011fuk, tad\u0131 ac\u0131 ve keskin, r\u00fczgar\u0131 da\u011f\u0131tma, ate\u015fi d\u00fc\u015f\u00fcrme, di\u00fcrez, kan dola\u015f\u0131m\u0131n\u0131 te\u015fvik etme, detoksifikasyon ve \u015fi\u015fli\u011fi azaltma gibi i\u015flevlere sahiptir. So\u011fuk alg\u0131nl\u0131\u011f\u0131, ate\u015f, romatizma, kemik a\u011fr\u0131s\u0131, \u00e7ocukluk \u00e7a\u011f\u0131 r\u00fczgar \u015foku, idrar yapma zorlu\u011fu, ishal, f\u0131t\u0131k, travmatik yaralanma, \u0131s\u0131 toksin \u00fclserleri, egzama vb. i\u00e7in kullan\u0131l\u0131r. Ara\u015ft\u0131rmalar, kokar otun kumarinler, alkaloidler, flavonoidler, lignin ve polifenoller a\u00e7\u0131s\u0131ndan zengin oldu\u011funu ortaya koymu\u015ftur. Mevcut aktivite \u00e7al\u0131\u015fmalar\u0131, kokar otun anti spazmodik, anti-t\u00fcm\u00f6r, antibakteriyel ve anti fertilite aktivitelerine sahip oldu\u011funu g\u00f6stermi\u015ftir. Is\u0131 temizleyici ve detoksifiye edici bitkilerin antiviral etkilerinin ara\u015ft\u0131r\u0131lmas\u0131na dayanarak, kokar otun 95% etanol ekstrakt\u0131n\u0131n EB vir\u00fcs DNA par\u00e7alanmas\u0131 ve replikasyonuna kar\u015f\u0131 \u00f6nemli in vitro inhibit\u00f6r aktiviteye sahip oldu\u011fu bulunmu\u015ftur. Bu nedenle, anti EB vir\u00fcs\u00fc aktif bile\u015fenlerini ara\u015ft\u0131rmak i\u00e7in, aktivite odakl\u0131 bir ay\u0131rma y\u00f6ntemi kulland\u0131k ve aktif bile\u015fenin diklorometan ekstraksiyon b\u00f6lgesinde bulundu\u011funu tespit ettik. Bu bile\u015fen \u00fczerinde sistematik bir kimyasal bile\u015fim \u00e7al\u0131\u015fmas\u0131 y\u00fcr\u00fctt\u00fck. EBV'ye kar\u015f\u0131 kokulu otun farmakolojik madde temelini a\u00e7\u0131kl\u0131\u011fa kavu\u015fturmak ve t\u0131bbi de\u011ferinin daha da geli\u015ftirilmesi ve kullan\u0131lmas\u0131 i\u00e7in teorik temel sa\u011flamak amac\u0131yla.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5683\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-167.png\" alt=\"\" width=\"758\" height=\"676\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5684\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-153.png\" alt=\"\" width=\"325\" height=\"252\" \/><br \/>\nKokar ot, \u00f6zel bir aromaya sahip, t\u0131bbi ama\u00e7larla kullan\u0131lan \u00e7ok y\u0131ll\u0131k otsu bir bitkidir. Akdeniz k\u0131y\u0131lar\u0131na \u00f6zg\u00fcd\u00fcr ve \u00c7in'in hem kuzeyinde hem de g\u00fcneyinde, \u00e7o\u011funlukla saks\u0131 bitkileri halinde ekilir. Bu deneyde, 95% koku\u015fmu\u015f otunun diklorometan ekstrakt\u0131n\u0131n kimyasal bile\u015fimini incelemek i\u00e7in modern kromatografik teknikler kullan\u0131lm\u0131\u015ft\u0131r. Akridon alkaloidleri olan 1-13 numaral\u0131 bile\u015fikler, kinolon alkaloidleri olan 24 ve 25 numaral\u0131 bile\u015fikler, kumarinler olan 14-23 numaral\u0131 bile\u015fikler ve aromatik alkoller, ketonlar, flavonoid glikozitler ve difenilpropanoid glikozitler gibi di\u011fer bile\u015fikler dahil olmak \u00fczere otuz bile\u015fik izole edilmi\u015ftir. Bile\u015fik 2, 7, 9, 12, 20, 22, 23, 26, 27, 28 ve 30 ilk kez bu bitkiden izole edilmi\u015ftir. Elde edilen bile\u015fikler, EBV lizisi ve replikasyonu \u00fczerindeki inhibit\u00f6r aktivitelerinin yan\u0131 s\u0131ra sitotoksik aktiviteleri a\u00e7\u0131s\u0131ndan taranm\u0131\u015ft\u0131r. Sonu\u00e7lardan, 5, 14, 20, 24, 25 ve 27 dahil olmak \u00fczere alt\u0131 bile\u015fik EBV lizis ve replikasyon aktivitesinin \u00f6nemli \u00f6l\u00e7\u00fcde inhibisyonunu g\u00f6stermi\u015ftir. Bunlar aras\u0131nda, 5 ve 24 numaral\u0131 bile\u015fikler, pozitif kontrol olan dekstrorutinden daha y\u00fcksek EBV inhibisyon aktivitesi sergilemi\u015ftir. \u015eu anda, \u00f6zellikle influenza vir\u00fcs\u00fc ve herpes vir\u00fcs\u00fcne odaklanan, koku\u015fmu\u015f otun antiviral aktif bile\u015fenleri hakk\u0131nda nispeten az say\u0131da rapor bulunmaktad\u0131r. Antiviral aktivitenin maddi temelini daha fazla incelemek amac\u0131yla, EBV b\u00f6l\u00fcnmesi ve replikasyonu \u00fczerinde iyi inhibit\u00f6r aktiviteye sahip bile\u015fikler elde etmek i\u00e7in alkaloidlere odaklanarak kimyasal bile\u015fimini ara\u015ft\u0131rmaya devam edece\u011fiz. Bu \u00e7al\u0131\u015fma, kokar otun kimyasal bile\u015fim bilgisini zenginle\u015ftirerek, kokar otun t\u0131bbi de\u011ferinin daha da geli\u015ftirilmesi i\u00e7in maddi bir temel ve bilimsel dayanak sa\u011flamaktad\u0131r. EBV inhibit\u00f6r aktivitesine sahip 5 ve 24 numaral\u0131 bile\u015fikler, nazofaringeal karsinom ila\u00e7lar\u0131n\u0131n geli\u015ftirilmesi i\u00e7in aktif iskeletler sa\u011flamaktad\u0131r.<\/p>","protected":false},"excerpt":{"rendered":"<p>Study on the Chemical Components of Dichloromethane Part in Stinky Grass Yuncao is the whole plant of Ruta graveolens L. in the Rutaceae family, a perennial herbaceous plant with a strong odor. It is also known as stinky wormwood (Guangxi Herbal Medicine), small herb (Guangxi Plant List), and catnip seven (Guangxi Herbal Medicine). Picking in [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Study on the Chemical Components of Dichloromethane Part in Stinky Grass - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/kokusmus-cimen\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study on the Chemical Components of Dichloromethane Part in Stinky Grass - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Study on the Chemical Components of Dichloromethane Part in Stinky Grass Yuncao is the whole plant of Ruta graveolens L. in the Rutaceae family, a perennial herbaceous plant with a strong odor. 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