{"id":5571,"date":"2024-08-04T19:52:26","date_gmt":"2024-08-04T19:52:26","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5571"},"modified":"2024-08-04T19:52:26","modified_gmt":"2024-08-04T19:52:26","slug":"tobacco-mosaic-virus","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/tobacco-mosaic-virus\/","title":{"rendered":"Qianli Guang'\u0131n Kimyasal Bile\u015fimi ve Anti T\u00fct\u00fcn Mozaik Vir\u00fcs\u00fc Aktivitesi \u00dczerine \u00c7al\u0131\u015fma"},"content":{"rendered":"

Qianli Guang'\u0131n Kimyasal Bile\u015fimi ve Anti T\u00fct\u00fcn Mozaik Vir\u00fcs\u00fc Aktivitesi \u00dczerine \u00c7al\u0131\u015fma
\n\"Bitki kanserleri\" olarak da bilinen bitki viral hastal\u0131klar\u0131, fungal hastal\u0131klardan sonra en b\u00fcy\u00fck ikinci bitki hastal\u0131\u011f\u0131d\u0131r. \u0130deal \u00f6nleme ve kontrol tedbirlerinin eksikli\u011fi nedeniyle, tar\u0131msal \u00fcretimde b\u00fcy\u00fck kay\u0131plara neden olurlar ve bitki vir\u00fcslerinin neden oldu\u011fu ekonomik kay\u0131plar y\u0131ll\u0131k $10 milyar\u0131 a\u015fmaktad\u0131r. T\u00fct\u00fcn mozaik vir\u00fcs\u00fc (TMV), 65 familyadan 885 bitki t\u00fcr\u00fcn\u00fc i\u00e7eren geni\u015f bir konuk\u00e7u yelpazesine sahip, ke\u015ffedilen en eski tek sarmall\u0131 RNA bitki vir\u00fcs\u00fcd\u00fcr. T\u00fct\u00fcn ve di\u011fer \u00fcr\u00fcnler TMV ile enfekte olduktan sonra, enfekte olmu\u015f bitkilerin yapraklar\u0131ndaki klorofil yok olur ve bu da fotosentezin azalmas\u0131na, b\u00fcy\u00fcme zorluklar\u0131na, c\u00fcceli\u011fe ve hatta \u00f6l\u00fcme yol a\u00e7ar. T\u00fct\u00fcn \u00c7in'de \u00f6nemli bir ekonomik \u00fcr\u00fcnd\u00fcr ve TMV her y\u0131l t\u00fct\u00fcn \u00fcretiminde ve kalitesinde ciddi kay\u0131plara neden olmaktad\u0131r. \u0130lgili veri istatistiklerine g\u00f6re, t\u00fct\u00fcn mozaik vir\u00fcs\u00fcn\u00fcn neden oldu\u011fu ekonomik kay\u0131plar her y\u0131l 100 milyon ABD dolar\u0131na ula\u015fmaktad\u0131r ve TMV'yi kontrol etmek nispeten zordur. TMV'ye kar\u015f\u0131 birka\u00e7 ticari antiviral ajan kullan\u0131ma sunulmu\u015f olsa da, \u00e7ok az say\u0131da etkili ve pratik \u00e7e\u015fit bulunmaktad\u0131r. Bu nedenle, etkili ve d\u00fc\u015f\u00fck toksisiteli yeni anti TMV ila\u00e7lar\u0131n\u0131n geli\u015ftirilmesi acildir.
\nAsteraceae familyas\u0131n\u0131n en b\u00fcy\u00fck cinsi olan Senecio cinsi, 1500'den fazla t\u00fcr i\u00e7erir ve 160'tan fazlas\u0131 \u00c7in'de da\u011f\u0131l\u0131m g\u00f6sterir. Senecio scandens, Senecio cinsinin \u00e7ok y\u0131ll\u0131k bir bitkisidir. G\u00f6vdeleri genellikle k\u0131vr\u0131ml\u0131 ve t\u0131rman\u0131c\u0131d\u0131r, \u00fcst k\u0131sm\u0131nda birden fazla dal bulunur. Ba\u015f \u015feklinde bir \u00e7i\u00e7ek salk\u0131m\u0131na, sar\u0131 \u00e7i\u00e7eklere ve oval \u00fc\u00e7gen veya eliptik m\u0131zrak \u015feklinde yapraklara sahiptir. \u00c7o\u011funlukla do\u011fu, orta g\u00fcney ve g\u00fcneybat\u0131 \u00c7in'de da\u011f\u0131l\u0131m g\u00f6sterir ve \u00e7o\u011funlukla tepelik ve da\u011fl\u0131k ormanlarda, \u00e7al\u0131l\u0131klarda, otlaklarda ve yol kenarlar\u0131nda bulunur. Qianli Guang, \u0131s\u0131y\u0131 temizleme ve detoksifiye etme, g\u00f6r\u00fc\u015f\u00fc iyile\u015ftirme ve rutubeti giderme etkilerine sahip geleneksel bir \u00c7in \u015fifal\u0131 bitkisidir. Ayr\u0131ca iyi anti-enflamatuar, antibakteriyel ve antiviral etkilere sahiptir.
\nBu \u00e7al\u0131\u015fman\u0131n amac\u0131, Qianli Guang'da anti TMV aktivitesini taramak ve anti t\u00fct\u00fcn mozaik vir\u00fcs\u00fc aktivitesine sahip kimyasal bile\u015fenleri ara\u015ft\u0131rmakt\u0131r. Bunlardan en aktif bile\u015fiklerin se\u00e7ilmesi, t\u00fct\u00fcn mozaik hastal\u0131\u011f\u0131n\u0131n \u00f6nlenmesi ve kontrol\u00fc i\u00e7in teorik bir temelin yan\u0131 s\u0131ra Senecio bitkilerinin kaynak kullan\u0131m\u0131 i\u00e7in bilimsel bir temel sa\u011flar.<\/p>\n

\"\"\"\"
\nBitkiler alemi, bitki vir\u00fcslerine kar\u015f\u0131 koyabilen aktif maddeler de dahil olmak \u00fczere 400000'den fazla ikincil metabolit \u00fcretir ve bitkilerin kendileri taraf\u0131ndan \u00fcretilen kimyasal savunma maddeleri d\u00fc\u015f\u00fck \u00f6z toksisiteye sahiptir ve \u00e7evre dostudur. Bu nedenle, bitkilerden anti TMV aktif maddeleri aramak \u00e7ok uygun bir yoldur ve son y\u0131llarda bir\u00e7ok rapor yay\u0131nlanm\u0131\u015ft\u0131r.
\nBu \u00e7al\u0131\u015fmada, Senecio asiatica'n\u0131n etil asetat ekstrakt\u0131ndan 13 monomerik bile\u015fi\u011fi izole etmek i\u00e7in modern ve etkili fitokimyasal ay\u0131rma y\u00f6ntemleri kullan\u0131lm\u0131\u015ft\u0131r. Bile\u015fik 7 ve 10 hari\u00e7, di\u011fer t\u00fcm bile\u015fikler Senecio asiatica'dan ilk kez izole edilmi\u015ftir. Anti-t\u00fct\u00fcn mozaik vir\u00fcs\u00fc aktivite testinin sonu\u00e7lar\u0131, bile\u015fik 8'in TMV ile enfekte t\u00fct\u00fcn yapraklar\u0131n\u0131n koruyucu etkisi \u00fczerinde Ningnanmycin'den \u00f6nemli \u00f6l\u00e7\u00fcde daha y\u00fcksek bir inhibit\u00f6r orana sahip oldu\u011funu g\u00f6stermi\u015ftir; Bile\u015fik 1, 4, 9-13, Ningnan mycin ile kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda Xinye t\u00fct\u00fcn\u00fcne kar\u015f\u0131 koruyucu etkilerde \u00f6nemli bir fark g\u00f6stermemi\u015ftir, bu da bu bile\u015fiklerin t\u00fct\u00fcn\u00fcn vir\u00fcslere kar\u015f\u0131 bitki sistemik direnci kazanmas\u0131na neden olabilece\u011fini g\u00f6stermektedir. Bile\u015fik 13'\u00fcn t\u00fct\u00fcn enfeksiyonu TMV'nin terap\u00f6tik etkisi \u00fczerindeki inhibit\u00f6r oran\u0131 Ningnanmycin'den daha y\u00fcksektir; Bile\u015fik 9'un inhibisyon oran\u0131 Ningnanmycin ile kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda \u00f6nemli bir fark g\u00f6stermemi\u015ftir. Bile\u015fik 8 ve 9'un TMV \u00fczerindeki in vitro inaktivasyon etkisinde Ningnanmycin'in inhibisyon oran\u0131na k\u0131yasla \u00f6nemli bir fark yoktu, bu da bu iki bile\u015fi\u011fin anti TMV etkileri g\u00f6stermek i\u00e7in do\u011frudan vir\u00fcs \u00fczerinde etkili olabilece\u011fini g\u00f6stermektedir.
\n\u00d6zetle, Senecio grandiflorus'un kimyasal bile\u015fenleri TMV \u00fczerinde \u00f6nemli bir inhibit\u00f6r etkiye sahiptir; alkaloidler, terpenler ve baz\u0131 flavonoidler g\u00fc\u00e7l\u00fc anti TMV aktivitesi g\u00f6stermektedir. Bu bile\u015fenlerin ana antiviral aktif bile\u015fenler olup olmad\u0131\u011f\u0131 daha fazla ara\u015ft\u0131r\u0131lmaya de\u011ferdir. Bu \u00e7al\u0131\u015fma, Senecio grandiflorus kimyasal bile\u015fenlerinin ve biyolojik aktivitelerinin kapsam\u0131n\u0131 zenginle\u015ftirmekte ve gelecekte t\u00fct\u00fcn mozaik hastal\u0131\u011f\u0131n\u0131n ye\u015fil \u00f6nlenmesi ve kontrol\u00fc i\u00e7in bilimsel bir temel sa\u011flamaktad\u0131r.<\/p>","protected":false},"excerpt":{"rendered":"

Qianli Guang'\u0131n Kimyasal Bile\u015fimi ve Anti T\u00fct\u00fcn Mozaik Vir\u00fcs\u00fc Aktivitesi \u00dczerine \u00c7al\u0131\u015fma \"Bitki kanserleri\" olarak da bilinen bitki viral hastal\u0131klar\u0131, mantar hastal\u0131klar\u0131ndan sonra en b\u00fcy\u00fck ikinci bitki hastal\u0131klar\u0131d\u0131r. \u0130deal \u00f6nleme ve kontrol \u00f6nlemlerinin eksikli\u011fi nedeniyle, bitki vir\u00fcslerinin neden oldu\u011fu ekonomik kay\u0131plarla tar\u0131msal \u00fcretimde b\u00fcy\u00fck kay\u0131plara neden olurlar [...]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nStudy on the Chemical Composition and Anti Tobacco Mosaic Virus Activity of Qianli Guang - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/tobacco-mosaic-virus\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study on the Chemical Composition and Anti Tobacco Mosaic Virus Activity of Qianli Guang - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Study on the Chemical Composition and Anti Tobacco Mosaic Virus Activity of Qianli Guang Plant viral diseases, also known as “plant cancers,” are the second largest plant diseases after fungal diseases. 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