{"id":5455,"date":"2024-08-04T19:12:10","date_gmt":"2024-08-04T19:12:10","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5455"},"modified":"2024-08-04T19:12:10","modified_gmt":"2024-08-04T19:12:10","slug":"gentiana-scabra","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/gentiana-scabra\/","title":{"rendered":"Wuling'de Gentiana scabra'n\u0131n Kimyasal Bile\u015fenleri ve Antienflamatuar Aktiviteleri \u00dczerine Ara\u015ft\u0131rma"},"content":{"rendered":"

Wuling'de Gentiana scabra'n\u0131n Kimyasal Bile\u015fenleri ve Antienflamatuar Aktiviteleri \u00dczerine Ara\u015ft\u0131rma
\nGentianaceae familyas\u0131na ve Gentiana cinsine ait olan Gentiana davidii Franch. bitkisinin tamam\u0131 Gentiana davidii Franch. \u00c7imenli yama\u00e7larda ve 350-2500 metre derinliklerdeki ormanlar\u0131n alt\u0131nda yeti\u015fir ve \u00e7o\u011funlukla Hunan, Zhejiang, Fujian, Jiangxi ve di\u011fer b\u00f6lgelerde da\u011f\u0131l\u0131m g\u00f6sterir. Yaz veya sonbaharda hasat edilir, y\u0131kan\u0131r, kurutulur veya taze olarak t\u00fcketilir. Qing Hanedanl\u0131\u011f\u0131'n\u0131n \"Wentang Koleksiyonu Do\u011frulama Form\u00fcl\u00fc\" ve \"\u00c7in Bitkisel \u0130la\u00e7lar\u0131n\u0131n Ulusal Derlemesi \"ne g\u00f6re, Jiutouqing olarak da bilinen Wuling Gentiana ve yer lotusu olarak da bilinen \"Chinese Materia Medica\" \u00e7e\u015fitli etnik t\u0131p kitaplar\u0131nda kaydedilmi\u015ftir. Ac\u0131 bir tad\u0131 ve so\u011fuk bir yap\u0131s\u0131 vard\u0131r. Is\u0131y\u0131 temizleme, detoksifiye etme ve rutubeti giderme etkilerine sahiptir. \u00d6zellikle r\u00fczgar \u015foku, k\u0131rm\u0131z\u0131 g\u00f6zler, bo\u011faz a\u011fr\u0131s\u0131, hepatit, dizanteri, bel so\u011fuklu\u011fu, s\u00fcp\u00fcratif osteomiyelit, apse \u015fi\u015fmesi ve zehirli y\u0131lan \u0131s\u0131r\u0131klar\u0131 olan \u00e7ocuklar\u0131 tedavi etmek i\u00e7in kullan\u0131l\u0131r. Bir halk ilac\u0131 olarak Wuling Gentiana'n\u0131n uzun bir kullan\u0131m ge\u00e7mi\u015fi ve \u00f6nemli terap\u00f6tik etkileri vard\u0131r. Esas olarak akci\u011fer \u0131s\u0131 \u00f6ks\u00fcr\u00fc\u011f\u00fc, endometrit ve s\u00fcp\u00fcratif osteomiyelit gibi iltihapla ilgili hastal\u0131klar\u0131 tedavi etmek i\u00e7in kullan\u0131l\u0131r. Bununla birlikte, kimyasal bile\u015fimi ve farmakolojik etkileri \u00fczerine yap\u0131lan ara\u015ft\u0131rmalar \u015fu anda nispeten zay\u0131ft\u0131r. Ayn\u0131 cinse ait bir bitki olan Gentiana scabra'n\u0131n ara\u015ft\u0131r\u0131lmas\u0131yla ilgili bir\u00e7ok rapor bulunmaktad\u0131r. Esas olarak anti-enflamatuar, hepatoprotektif ve antioksidan etkiler gibi farmakolojik aktivitelere sahip sikloheksen eter terpenler, flavonoidler ve triterpenler i\u00e7erir. Gentiana scabra'n\u0131n ara\u015ft\u0131rma temeline dayanan bu deney, Gentiana scabra'n\u0131n anti-enflamatuar ve farmakolojik madde temelini incelemek i\u00e7in kolon kromatografisi, spektroskopik teknikler ve h\u00fccre aktivitesi tarama y\u00f6ntemlerini kullanarak Gentiana scabra t\u0131bbi materyallerinin geli\u015ftirilmesi i\u00e7in deneysel temel sa\u011flar.<\/p>\n

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\nGentiana scabra'n\u0131n ekstraksiyonu ve ayr\u0131\u015ft\u0131r\u0131lmas\u0131 yoluyla, 6 triterpenoid, 1 fenilpropanoid, 3 sterol ve 5 di\u011fer bile\u015fik olmak \u00fczere toplam 15 bile\u015fik elde edilmi\u015ftir. Bunlardan 7, 14 ve 15'i Gentiana scabra'dan ilk kez izole edilirken, geri kalan bile\u015fikler Gentiana scabra'dan ilk kez izole edilmi\u015ftir. Triterpenoidler Gentiana bitkilerinin \u00f6nemli bile\u015fenleridir ve en yayg\u0131n olanlar\u0131 oleanane ve Ussuriane tipi pentasiklik triterpenoidlerdir. Anti-enflamatuar, antibakteriyel, imm\u00fcnomod\u00fclat\u00f6r ve hepatoprotektif etkilere sahiptirler ve Gentiana bitkilerinin t\u0131bbi maddeleridir. Anti-enflamatuar aktivite taramas\u0131 yoluyla, Wuling Gentiana'dan izole edilen oleanolik asit ve ursolik asidin, Wuling Gentiana'n\u0131n anti-enflamatuar aktivitesinin farmakolojik maddeleri olan belirli anti-enflamatuar aktiviteye sahip oldu\u011fu bulunmu\u015ftur. Bu makalede izole edilen bile\u015fikler esas olarak Gentiana scabra'n\u0131n etil asetat ekstraksiyon b\u00f6lgesinden gelmektedir. Gentiana scabra'n\u0131n iridoid ve flavonoid bile\u015fenleri esas olarak gentiopicroside, swertiamarin ve luteolin gibi glikozit bile\u015fenlerinden olu\u015fur. Glikozit bile\u015fenlerinin polaritesi y\u00fcksektir, bu nedenle Gentiana scabra'n\u0131n iridoid ve flavonoid bile\u015fenlerinin n-b\u00fctanol ekstraksiyon b\u00f6lgesinde mevcut oldu\u011fu tahmin edilmektedir. Bu konuda daha fazla ara\u015ft\u0131rma yap\u0131lacakt\u0131r. \u00d6zet olarak, bu \u00e7al\u0131\u015fma Gentiana scabra'n\u0131n kimyasal bile\u015fimi ve farmakolojik aktivitesi \u00fczerine yap\u0131lan ara\u015ft\u0131rmalar\u0131 zenginle\u015ftirmekte, anti-enflamatuar aktivitesinin maddi temelini ayd\u0131nlatmakta ve daha ileri ara\u015ft\u0131rma ve geli\u015ftirme i\u00e7in bir referans sa\u011flamaktad\u0131r.<\/p>","protected":false},"excerpt":{"rendered":"

Research on the Chemical Components and Anti inflammatory Activities of Gentiana scabra in Wuling Gentiana davidii Franch., belonging to the Gentianaceae family and Gentiana genus, is the entire plant of Gentiana davidii Franch. It grows in grassy slopes and under forests at depths of 350-2500 meters and is mainly distributed in Hunan, Zhejiang, Fujian, Jiangxi, […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nResearch on the Chemical Components and Anti inflammatory Activities of Gentiana scabra in Wuling - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/gentiana-scabra\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research on the Chemical Components and Anti inflammatory Activities of Gentiana scabra in Wuling - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Research on the Chemical Components and Anti inflammatory Activities of Gentiana scabra in Wuling Gentiana davidii Franch., belonging to the Gentianaceae family and Gentiana genus, is the entire plant of Gentiana davidii Franch. 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