{"id":5422,"date":"2024-08-04T18:56:29","date_gmt":"2024-08-04T18:56:29","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5422"},"modified":"2024-08-04T18:56:29","modified_gmt":"2024-08-04T18:56:29","slug":"rhizoma-alismatis","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/rhizoma-alismatis\/","title":{"rendered":"Alisma orientalis i\u00e7in taze kesim ve i\u015fleme teknolojisinin genel de\u011ferlendirme normalle\u015ftirme y\u00f6ntemi ile birlikte yan\u0131t y\u00fczeyi metodolojisine dayal\u0131 optimizasyonu"},"content":{"rendered":"

Alisma orientalis i\u00e7in taze kesim ve i\u015fleme teknolojisinin genel de\u011ferlendirme normalle\u015ftirme y\u00f6ntemi ile birlikte yan\u0131t y\u00fczeyi metodolojisine dayal\u0131 optimizasyonu
\n\u00c7in bitkisel ilac\u0131 Alisma orien tale (Sam.) Juzep. veya Alisma plantago aquatica Linn., Alismataceae familyas\u0131ndan Alisma orien tale (Sam.) bitkisinin kurutulmu\u015f yumrusudur. \u00c7in Halk Cumhuriyeti Farmakopesi'nin (bundan b\u00f6yle \"\u00c7in Farmakopesi\" olarak an\u0131lacakt\u0131r) 2020 bask\u0131s\u0131nda yer almaktad\u0131r ve su ve nemi te\u015fvik etme, \u0131s\u0131y\u0131 hafifletme ve bulan\u0131kl\u0131\u011f\u0131 ve kolesterol\u00fc azaltma etkilerine sahiptir. Esas olarak idrar rahats\u0131zl\u0131\u011f\u0131, \u00f6dem ve dolgunluk, ishal ve olig\u00fcri, balgam kaynakl\u0131 ba\u015f d\u00f6nmesi, \u0131s\u0131 kaynakl\u0131 a\u011fr\u0131, hiperlipidemi vb. i\u00e7in kullan\u0131l\u0131r.<\/p>\n

\u00c7in \u015fifal\u0131 otlar\u0131n\u0131n ve Alisma kaynatma par\u00e7alar\u0131n\u0131n geleneksel i\u015fleme s\u00fcreci safla\u015ft\u0131rma, kurutma, safs\u0131zl\u0131k giderme, tekrarlanan kurutma ve \u015fifal\u0131 otlara i\u015fleme, ard\u0131ndan \u0131slatma, nemlendirme, kal\u0131n dilimler halinde kesme ve ard\u0131ndan kaynatma par\u00e7alar\u0131 halinde kurutmay\u0131 i\u00e7erir. T\u00fcm s\u00fcre\u00e7 tekrarlanan dald\u0131rma ve iki kurutma ad\u0131m\u0131 gerektirir ki bunlar s\u0131k\u0131c\u0131, zaman al\u0131c\u0131 ve emek yo\u011fundur. Esas olarak geleneksel el deneyimine dayan\u0131r, g\u00fc\u00e7l\u00fc \u00f6znellik, d\u00fc\u015f\u00fck mekanizasyon ve kontrol edilmesi zordur, bu da end\u00fcstriyel geli\u015fime elveri\u015fli de\u011fildir. Ulusal T\u0131bbi \u00dcr\u00fcnler \u0130daresi Kapsaml\u0131 Departman\u0131'n\u0131n \u00c7in bitkisel ila\u00e7lar\u0131n\u0131n (taze kesim) \u00fcretim alan\u0131ndaki \u00c7in bitkisel ila\u00e7 \u00fcretim i\u015fletmeleri taraf\u0131ndan tedarik edilmesi ve i\u015flenmesine ili\u015fkin cevab\u0131 (\u0130la\u00e7 \u0130daresi Kapsaml\u0131 \u0130la\u00e7 \u0130daresi Mektubu [2021] No. 367) a\u00e7\u0131k\u00e7a \"taze kesim, hasat edilen taze \u00c7in bitkisel ila\u00e7lar\u0131n\u0131 dilimler, segmentler, bloklar, yapraklar vb. halinde kesen \u00fcretim alan\u0131ndaki i\u015fleme y\u00f6ntemlerinden biridir. \u00c7in bitkisel ila\u00e7lar\u0131n\u0131n \u015feklini de\u011fi\u015ftirse de \u00f6zelliklerini de\u011fi\u015ftirmez ve \u00c7in bitkisel ila\u00e7lar\u0131n\u0131n kurutulmas\u0131, \u0131slat\u0131lmas\u0131, kesilmesi ve yeniden kurutulmas\u0131 gibi i\u015flem ad\u0131mlar\u0131n\u0131 belirli bir \u00f6l\u00e7\u00fcde azalt\u0131r, bu da \u00c7in bitkisel ila\u00e7lar\u0131n\u0131n kalitesinin sa\u011flanmas\u0131na yard\u0131mc\u0131 olur.\" Alisma i\u00e7in taze kesim i\u015fleme teknolojisi \u00fczerine ara\u015ft\u0131rma yapman\u0131n ve bunu end\u00fcstriyel \u00fcretime daha fazla uygulaman\u0131n, \u00c7in bitkisel ila\u00e7 end\u00fcstrisinin y\u00fcksek kaliteli geli\u015fme e\u011filimiyle son derece uyumlu oldu\u011fu g\u00f6r\u00fclebilir. Ancak \u015fu anda ilgili ara\u015ft\u0131rma raporlar\u0131 bulunmamaktad\u0131r.<\/p>\n

Geleneksel \u00c7in t\u0131bb\u0131n\u0131n kalitesini etkileyen bir\u00e7ok fakt\u00f6r vard\u0131r ve kimyasal bile\u015fimi karma\u015f\u0131kt\u0131r. Bir veya iki aktif bile\u015fenin test edilmesi, bunlar\u0131n kalitesini ve genel etkinli\u011fini tam olarak yans\u0131tamaz. \u015eu anda \u00c7in Farmakopesinde kay\u0131tl\u0131 olan alisol B 23 asetat (23-AB) ve alisol C 23 asetata (23-AC) ek olarak, 24 asetil alisol A (24-AA), alisol B (AB) ve alisol polisakkaritler de geleneksel \u00c7in ilac\u0131 Alisma'da \u00f6nemli etken maddelerdir. Bu nedenle, Alisma i\u00e7in \u00c7in Farmakopesi kapsam\u0131nda belirtilen \u00f6zellikler, alkolde \u00e7\u00f6z\u00fcn\u00fcr ekstraktlar (ASE), toplam 23-AB ve 23-AC i\u00e7eri\u011fi gibi kalite de\u011ferlendirme g\u00f6stergelerine dayanarak, bu \u00e7al\u0131\u015fma ilk kez Alismata Rhizoma triterpenoidleri (ART), Alismata Rhizoma polisakkaritleri (ARP), 24-AA, AB, vb. i\u00e7eri\u011fini de de\u011ferlendirme g\u00f6stergelerine dahil ederek Alisma t\u0131bbi malzemelerinin kalitesini daha kapsaml\u0131 bir \u015fekilde yans\u0131tmay\u0131 ama\u00e7lam\u0131\u015ft\u0131r.<\/p>\n

Bu nedenle, erken a\u015famada Alisma i\u015fleme teknolojisini etkileyen ana fakt\u00f6rlerin a\u00e7\u0131kl\u0131\u011fa kavu\u015fturulmas\u0131na dayanan bu makale, tek fakt\u00f6rl\u00fc deneyler yoluyla her bir fakt\u00f6r\u00fcn parametre aral\u0131\u011f\u0131n\u0131 belirlemekte, Alisma'n\u0131n taze kesim i\u015fleme teknolojisini daha da optimize etmek i\u00e7in genel de\u011ferlendirme normalle\u015ftirme y\u00f6ntemiyle birlikte yan\u0131t y\u00fczeyi metodolojisini kullanmakta ve Alisma \u00fcretim alanlar\u0131 i\u00e7in daha iyi bir i\u015fleme y\u00f6ntemi elde etmek, Alisma i\u015fleme end\u00fcstrisinin standartla\u015ft\u0131r\u0131lm\u0131\u015f ve b\u00fcy\u00fck \u00f6l\u00e7ekli geli\u015fimi i\u00e7in referans sa\u011flamak ve Alisma ile ilgili \u00fcr\u00fcnlerin kalitesini art\u0131rmak amac\u0131yla geleneksel i\u015fleme y\u00f6ntemiyle kar\u015f\u0131la\u015ft\u0131rmaktad\u0131r.<\/p>\n

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\nMen\u015fe yerindeki i\u015fleme ve kaynatma par\u00e7alar\u0131n\u0131n i\u015flenmesi, geleneksel \u00c7in t\u0131bb\u0131n\u0131n kalitesini do\u011frudan etkilemekte ve geleneksel \u00c7in patentli ila\u00e7lar\u0131n ve basit preparatlar\u0131n \u00fcretimini ve klinik uygulamas\u0131n\u0131 daha da etkilemektedir. \u00dcretim alanlar\u0131nda Alisma officinalis t\u0131bbi malzemelerinin mevcut \u00fcretimi ve i\u015flenmesine gelince, y\u0131ll\u0131k \u00fcretim ulusal Alisma officinalis t\u0131bbi malzemelerinin 80%'sinden fazlas\u0131n\u0131 olu\u015fturmas\u0131na ra\u011fmen, da\u011f\u0131n\u0131k i\u015fleme sahalar\u0131, k\u00fc\u00e7\u00fck \u00f6l\u00e7ek, mekanizasyon ve d\u00fc\u015f\u00fck standardizasyon gibi bir\u00e7ok sorun vard\u0131r. Alisma officinalis i\u00e7in k\u0131sa s\u00fcrede b\u00fcy\u00fck \u00f6l\u00e7ekli i\u015fleme talebi, s\u0131n\u0131rl\u0131 verimlili\u011fe sahip geleneksel at\u00f6lye tarz\u0131 i\u015fleme modu ile b\u00fcy\u00fck \u00f6l\u00e7\u00fcde \u00e7eli\u015fmekte, bu da Alisma officinalis'in e\u015fit olmayan kalitesiyle sonu\u00e7lanmakta ve klinik ila\u00e7lar\u0131 etkilemektedir. Bu nedenle, ara\u015ft\u0131rma ekibi erken a\u015famada taze kesilmi\u015f Alisma yapraklar\u0131n\u0131n i\u015flenmesi \u00fczerine bir \u00f6n fizibilite \u00e7al\u0131\u015fmas\u0131 y\u00fcr\u00fctm\u00fc\u015ft\u00fcr. Ara\u015ft\u0131rma sonucunda, geleneksel kesilmi\u015f t\u0131bbi par\u00e7alar\u0131n kalitesiyle kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda, taze kesilmi\u015f Alisma yapraklar\u0131n\u0131n kalitesinin tutarl\u0131 oldu\u011fu ve baz\u0131 g\u00f6stergelerde kalitenin daha iyi oldu\u011fu tespit edilmi\u015ftir: \u00d6zellikler a\u00e7\u0131s\u0131ndan, Alisma yapraklar\u0131n\u0131n kesilmi\u015f y\u00fczeyi daha beyazd\u0131r, dilimler daha d\u00fczg\u00fcnd\u00fcr ve k\u0131vr\u0131lm\u0131\u015f ve ezilmi\u015f dilimlerin ba\u015far\u0131s\u0131zl\u0131k oran\u0131 geleneksel kesilmi\u015f t\u0131bbi par\u00e7alardan daha d\u00fc\u015f\u00fckt\u00fcr; T\u0131bbi madde temeli a\u00e7\u0131s\u0131ndan, ASE, 23-AB ve 23-AC gibi farmakope kalite kontrol g\u00f6stergelerinin i\u00e7eri\u011fi geleneksel i\u015flenmi\u015f kaynatma par\u00e7alar\u0131ndan daha y\u00fcksektir ve daha kararl\u0131d\u0131r. Bu sonu\u00e7, bu makalenin \"2.4 Do\u011frulama Deneyi ve S\u00fcre\u00e7 Kar\u015f\u0131la\u015ft\u0131rma \u00c7al\u0131\u015fmas\u0131\" b\u00f6l\u00fcm\u00fcnde de tekrar do\u011frulanm\u0131\u015ft\u0131r. Ayn\u0131 zamanda, ara\u015ft\u0131rma grubunun \u00f6n saha ara\u015ft\u0131rmas\u0131 ve analizine g\u00f6re, Alisma'n\u0131n taze kesme ve i\u015fleme teknolojisi yaln\u0131zca geleneksel i\u015flemlerin ikincil infiltrasyon ve kurutma ad\u0131mlar\u0131n\u0131 azaltarak zamandan ve emekten tasarruf etmekle kalmaz, ayn\u0131 zamanda b\u00fcy\u00fck \u00f6l\u00e7ekli \u00fcretim i\u00e7in modern otomatik i\u015fleme ekipman\u0131 sunar, yak\u0131t ve i\u015f\u00e7ilik maliyetlerini etkili bir \u015fekilde azalt\u0131r ve geleneksel t\u0131bbi malzemeler ve kaynatma par\u00e7alar\u0131n\u0131n i\u015flenmesine k\u0131yasla \u00fcretim verimlili\u011fini art\u0131r\u0131r. Alisma'n\u0131n taze kesimi ve i\u015flenmesi, yo\u011fun ve standartla\u015ft\u0131r\u0131lm\u0131\u015f \u00fcretime daha fazla ula\u015fabilir ve Alisma t\u0131bbi malzemeleri i\u00e7in bir izlenebilirlik sistemi kurmak i\u00e7in uygun ko\u015fullar sa\u011flayarak, \u00c7in'in t\u00fcm geleneksel \u00c7in t\u0131bb\u0131 end\u00fcstrisi zincirinin y\u00fcksek kaliteli geli\u015ftirme ihtiya\u00e7lar\u0131na daha uygun olan Alisma t\u0131bbi malzemelerinin ve kaynatma par\u00e7alar\u0131n\u0131n kalitesinin istikrar\u0131n\u0131 sa\u011flayabilir. Dahas\u0131, Alisma Sichuan'da \u00f6nemli bir \u015fifal\u0131 bitki ve \u00fcnl\u00fc bir otantik bitkidir. Y\u0131ll\u0131k \u00fcretiminin 80%'den fazlas\u0131 Sichuan'daki Meishan ve Leshan \u015fehirleri gibi Minjiang Nehri Havzas\u0131nda yo\u011funla\u015fm\u0131\u015ft\u0131r. \u00dcretim alanlar\u0131n\u0131n yo\u011funla\u015fmas\u0131, Alisma i\u00e7in b\u00fcy\u00fck \u00f6l\u00e7ekli bir taze kesim ve i\u015fleme end\u00fcstrisinin geli\u015ftirilmesi i\u00e7in g\u00fc\u00e7l\u00fc do\u011fal ko\u015fullar sa\u011flam\u0131\u015ft\u0131r. \u00d6zetle, Alisma \u00fcr\u00fcnlerinin kalitesinin iyile\u015ftirilmesi, \u00fcretim s\u00fcre\u00e7lerinin basitle\u015ftirilmesi, \u00fcretim maliyetlerinin d\u00fc\u015f\u00fcr\u00fclmesi, yo\u011fun, standartla\u015ft\u0131r\u0131lm\u0131\u015f ve b\u00fcy\u00fck \u00f6l\u00e7ekli i\u015fleme end\u00fcstrilerinin geli\u015ftirilmesi ve bir Alisma kalite izlenebilirlik sisteminin kurulmas\u0131na ili\u015fkin kapsaml\u0131 analizden hareketle, Alisma'n\u0131n tazeyken kesilmesi ve i\u015flenmesi m\u00fcmk\u00fcnd\u00fcr ve g\u00fc\u00e7l\u00fc bir \u015fekilde geli\u015ftirilmelidir.
\nKurutma i\u015flemi s\u0131ras\u0131nda, h\u00fccreler taraf\u0131ndan su doldurma ve destekleme i\u015flevlerinin kaybedilmesi nedeniyle malzemenin hacminde bir azalma ve y\u00fczey k\u0131r\u0131\u015fmas\u0131 ya\u015fayaca\u011f\u0131n\u0131 belirtmek gerekir. Bununla birlikte, farkl\u0131 malzemeler kendi \u00f6zellikleri ve \u00e7e\u015fitli etkileyen fakt\u00f6rler nedeniyle yap\u0131sal de\u011fi\u015fikliklerde \u00f6nemli farkl\u0131l\u0131klara sahiptir. Bu nedenle, farkl\u0131 nem i\u00e7eriklerine sahip Alisma numunelerinin optimizasyon deneyine girerken nispeten tutarl\u0131 bir ba\u015flang\u0131\u00e7 durumuna sahip olmas\u0131n\u0131 sa\u011flamak i\u00e7in, \u00f6nceki deney \u00f6ncesi g\u00f6zlem sonu\u00e7lar\u0131na dayanarak, numune kurutma \u00f6n i\u015flemi 40 \u2103 gibi d\u00fc\u015f\u00fck bir s\u0131cakl\u0131kta ger\u00e7ekle\u015ftirilmi\u015ftir. Bu s\u0131cakl\u0131k ko\u015fulu alt\u0131nda, kurutulmu\u015f Alisma k\u00f6k yumru h\u00fccreleri yava\u015f\u00e7a su kaybeder ve k\u0131sa bir s\u00fcre i\u00e7inde \u00f6nemli bir de\u011fi\u015fiklik g\u00f6zlenmeden yava\u015f\u00e7a genel yap\u0131sal de\u011fi\u015fikliklere u\u011frar. Bu arada, tek fakt\u00f6rl\u00fc deneyin sonu\u00e7lar\u0131, 30% ila 50% nem i\u00e7eri\u011fine sahip Alisma rizomunun su i\u00e7eri\u011finin genel olarak g\u00f6r\u00fcn\u00fcm ve yap\u0131 bak\u0131m\u0131ndan tek tip oldu\u011funu g\u00f6stermi\u015ftir. Bu nedenle, Alisma rizomunun optimize edilmi\u015f deneyi i\u00e7in su i\u00e7eri\u011fi ara\u015ft\u0131rma aral\u0131\u011f\u0131 30% ila 50% olarak belirlenmi\u015ftir. \u00c7\u00fcnk\u00fc nem i\u00e7eri\u011fi 60% oldu\u011funda, beyaz meyve suyu kesilen y\u00fczeyden d\u0131\u015far\u0131 s\u0131zar; nem i\u00e7eri\u011fi 20% oldu\u011funda, d\u0131\u015f y\u00fczey nispeten serttir, dilimlenmesi zordur ve bo\u015fluklar ve d\u00f6k\u00fcnt\u00fcler \u00fcretmeye e\u011filimlidir.
\nKurutma s\u0131cakl\u0131\u011f\u0131, malzemelerdeki nemin buharla\u015fma oran\u0131n\u0131 etkiler. Kurutma s\u0131cakl\u0131\u011f\u0131 ne kadar y\u00fcksek olursa, nem buharla\u015fma oran\u0131 o kadar h\u0131zl\u0131 ve toplam kuruma s\u00fcresi o kadar k\u0131sa olur. Dilim kal\u0131nl\u0131\u011f\u0131 incedir ve kurutma i\u015flemi s\u0131ras\u0131nda malzemenin i\u00e7indeki nem h\u0131zl\u0131 bir \u015fekilde d\u0131\u015far\u0131ya do\u011fru yay\u0131l\u0131r, bu da toplam kuruma s\u00fcresinin k\u0131sa olmas\u0131na neden olur; Bununla birlikte, dilimlerin kal\u0131nl\u0131\u011f\u0131 kal\u0131nd\u0131r ve kurutma i\u015flemi s\u0131ras\u0131nda malzemenin i\u00e7indeki nemin dif\u00fczyon h\u0131z\u0131 yava\u015ft\u0131r, bu da kuruma s\u00fcresinin uzamas\u0131na neden olur. Bu \u00e7al\u0131\u015fmada, Alisma k\u00f6k yumrular\u0131n\u0131n nem i\u00e7eri\u011fi 40%, dilim kal\u0131nl\u0131\u011f\u0131 4 mm ve kurutma s\u0131cakl\u0131klar\u0131 40, 50 ve 60 \u2103 oldu\u011funda, toplam i\u015flem s\u00fcresi s\u0131ras\u0131yla 20-22, 10-12 ve 7-8 saat olmu\u015ftur. Yani, kurutma s\u0131cakl\u0131\u011f\u0131 artt\u0131k\u00e7a, i\u015flem s\u00fcresi k\u0131sald\u0131, ancak ayn\u0131 zamanda, Alisma k\u00f6k dilimlerinin enine kesitinin rengi giderek derinle\u015fti; Alisma k\u00f6ksap\u0131n\u0131n nem i\u00e7eri\u011fi 40%, kurutma s\u0131cakl\u0131\u011f\u0131 50 \u2103 ve dilim kal\u0131nl\u0131\u011f\u0131 3, 4 ve 5 mm oldu\u011funda, toplam i\u015flem s\u00fcresi s\u0131ras\u0131yla 7-8, 10-12 ve 18-20 saattir. Yani dilim kal\u0131nl\u0131\u011f\u0131 artt\u0131k\u00e7a i\u015flem s\u00fcresi uzamaktad\u0131r. \u00d6n tek fakt\u00f6rl\u00fc \u00f6n deney sonu\u00e7lar\u0131, dilim kal\u0131nl\u0131\u011f\u0131 2 mm oldu\u011funda, kuruma s\u00fcresinin 3-4 saat gibi son derece k\u0131sa oldu\u011funu, ancak \u00e7arp\u0131lma ve par\u00e7alanma gibi ciddi olaylar\u0131n oldu\u011funu g\u00f6stermektedir; Dilim kal\u0131nl\u0131\u011f\u0131 6 mm oldu\u011funda, sadece kuruma s\u00fcresi uzun olmakla kalmaz (30-32 saat), ayn\u0131 zamanda kuruduktan sonraki kal\u0131nl\u0131k \u00c7in Farmakopesi standard\u0131n\u0131 (4 mm) a\u015far.
\nModern ara\u015ft\u0131rmalara g\u00f6re, 80 \u2103 ve \u00fczeri y\u00fcksek s\u0131cakl\u0131klarda kurutulan Alisma officinalis'teki 23-AB ve 23-AC aktif bile\u015fenlerinin i\u00e7eri\u011fi, 60 \u2103 ve alt\u0131ndaki d\u00fc\u015f\u00fck s\u0131cakl\u0131klarda kurutulandan \u00f6nemli \u00f6l\u00e7\u00fcde daha d\u00fc\u015f\u00fckt\u00fcr. Y\u00fcksek s\u0131cakl\u0131kta kurutma i\u015flemi s\u0131ras\u0131nda 23-AB i\u00e7in iki d\u00f6n\u00fc\u015f\u00fcm yolu oldu\u011fu tahmin edilmektedir: biri alisol A 23 asetat (23-AA) olu\u015fturmak i\u00e7in halkay\u0131 oksitlemek ve a\u00e7mak, daha sonra 24-AA olu\u015fturmak i\u00e7in yap\u0131sal olarak yeniden d\u00fczenlemek ve alisol A (AA) olu\u015fturmak i\u00e7in daha fazla deasetilasyon yapmak; di\u011feri ise \u00f6nce AB olu\u015fturmak i\u00e7in deasetilasyon yapmak ve daha sonra AA'ya d\u00f6n\u00fc\u015ft\u00fcrmek i\u00e7in orijinal Alisma officinalis'teki AB ile birlikte halkay\u0131 oksitlemek ve a\u00e7makt\u0131r. 23-AC yap\u0131s\u0131 buna benzer ve ayn\u0131 d\u00f6n\u00fc\u015f\u00fcm yoluna sahip olabilir. Bu nedenle, Alisma officinalis i\u00e7in geleneksel \u00fcretim at\u00f6lyelerinin kalitesi b\u00fcy\u00fck \u00f6l\u00e7\u00fcde de\u011fi\u015fmektedir ve bunun, t\u0131bbi bile\u015fenlerinin d\u00f6n\u00fc\u015f\u00fcm\u00fcne ve azalmas\u0131na yol a\u00e7an i\u015fleme s\u0131cakl\u0131\u011f\u0131n\u0131n uygunsuz kontrol\u00fcyle yak\u0131ndan ili\u015fkili oldu\u011fu tahmin edilmektedir. \u00c7\u00fcnk\u00fc \u00f6n ara\u015ft\u0131rmaya g\u00f6re, baz\u0131 at\u00f6lyeler \u00e7o\u011funlukla manuel olarak i\u015fletilmekte, i\u015flem s\u00fcresini kontrol etmek ve maliyetleri d\u00fc\u015f\u00fcrmek i\u00e7in kurutma s\u0131cakl\u0131\u011f\u0131n\u0131 \u00e7ok y\u00fcksek olmaya zorlamaktad\u0131r. Alisma'n\u0131n taze kesim i\u015flemi bilimsel deneylerle do\u011frulanm\u0131\u015f ve bilimsel kurutma \u00f6n i\u015flemi, uygun nem i\u00e7eri\u011fi, dilim kal\u0131nl\u0131\u011f\u0131 ve i\u015fleme s\u0131cakl\u0131\u011f\u0131 i\u015flem parametrelerinin kombinasyonu bu sorunu etkili bir \u015fekilde \u00e7\u00f6zm\u00fc\u015ft\u00fcr.
\nBu nedenle, \u00f6nceki ara\u015ft\u0131rmalara dayanarak, bu makale ayr\u0131ca taze kesilmi\u015f Alisma'n\u0131n i\u015fleme teknolojisinin optimizasyonu \u00fczerine ara\u015ft\u0131rma yapmak i\u00e7in genel de\u011ferlendirme normalle\u015ftirme y\u00f6ntemi ile birlikte yan\u0131t y\u00fczeyi metodolojisini benimsemektedir. Taze kesilmi\u015f Alisma'n\u0131n i\u015fleme teknolojisini etkileyen merkezi noktalar, de\u011ferlendirme g\u00f6stergeleri olarak Alisma'n\u0131n g\u00f6r\u00fcn\u00fcm\u00fc ve enerji t\u00fcketimi ile tek fakt\u00f6rl\u00fc deneyler yoluyla belirlenmi\u015ftir. Taze Alisma'n\u0131n nem i\u00e7eri\u011fi 40%, dilim kal\u0131nl\u0131\u011f\u0131 4 mm ve kurutma s\u0131cakl\u0131\u011f\u0131 50 \u2103 idi. Bu temelde, yan\u0131t y\u00fczeyi metodolojisinin yan\u0131t de\u011feri olarak Alisma'n\u0131n i\u00e7 kalite de\u011ferlendirme kriterinin OD'si kullan\u0131larak, Design Expert 8.0.6 yaz\u0131l\u0131m\u0131 kullan\u0131larak yap\u0131lan analizle iyi uyum g\u00f6steren olduk\u00e7a anlaml\u0131 bir \u00e7oklu binom regresyon modeli elde edilmi\u015ftir. Varyans analizi ve yan\u0131t y\u00fczeyi metodolojisi sonu\u00e7lar\u0131, se\u00e7ilen i\u015flem y\u00f6nteminin g\u00fcvenilir oldu\u011funu g\u00f6stermektedir. Alisma'n\u0131n taze kesimi i\u00e7in nihai i\u015fleme teknolojisinin 37.01% nem i\u00e7eri\u011fine, 4.50 mm kesme kal\u0131nl\u0131\u011f\u0131na ve 49.36 \u2103 kurutma s\u0131cakl\u0131\u011f\u0131na sahip oldu\u011fu belirlenmi\u015ftir. Ger\u00e7ek end\u00fcstriyel \u00fcretim ihtiya\u00e7lar\u0131na dayanarak, Alisma'n\u0131n taze kesimi i\u00e7in en uygun i\u015fleme teknolojisi \u015fu \u015fekilde belirlenmi\u015ftir: nem i\u00e7eri\u011fi 40%, dilim kal\u0131nl\u0131\u011f\u0131 4 mm ve kurutma s\u0131cakl\u0131\u011f\u0131 50 \u2103 oldu\u011funda. Taze kesim i\u015fleme teknolojisinin g\u00fcvenilirli\u011fini do\u011frulamak i\u00e7in bu makale, optimum taze kesim i\u015fleme teknolojisine dayal\u0131 olarak \u00fc\u00e7 set tekrarlanan deney ger\u00e7ekle\u015ftirdi ve sonu\u00e7lar teknolojinin istikrarl\u0131 ve g\u00fcvenilir oldu\u011funu kan\u0131tlad\u0131; Alisma'n\u0131n taze kesimi i\u00e7in tercih edilen i\u015fleme teknolojisi, erken a\u015famada 40 \u2103'de \u00f6n kurutma yapmak ve ard\u0131ndan 12.0%'den daha d\u00fc\u015f\u00fck bir nem i\u00e7eri\u011fi elde etmek i\u00e7in dilimlemeden sonra 10-12 saat boyunca 50 \u2103'de kurutmakt\u0131r. Bu, geleneksel i\u015flemedeki y\u00fcksek s\u0131cakl\u0131k ve uzun kurutma s\u00fcresini \u00f6nler, triterpenoid bile\u015fenlerin d\u00f6n\u00fc\u015f\u00fcm\u00fcn\u00fc en aza indirir ve aktif bile\u015fenleri korur. Bu nedenle, geleneksel i\u015flenmi\u015f t\u0131bbi par\u00e7alarla kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda, taze kesilmi\u015f Alisma yapraklar\u0131n\u0131n i\u00e7 kalitesi daha iyidir. Alisma'n\u0131n taze kesim ve i\u015fleme teknolojisi, \u00c7in'deki Alisma t\u0131bbi malzemeleri ve kaynatma par\u00e7alar\u0131 i\u015fleme end\u00fcstrisinin t\u00fcm end\u00fcstri zincirinin standartla\u015ft\u0131r\u0131lm\u0131\u015f, b\u00fcy\u00fck \u00f6l\u00e7ekli ve y\u00fcksek kaliteli geli\u015fimi i\u00e7in m\u00fcmk\u00fcn olan en k\u0131sa s\u00fcrede bilimsel bir y\u00f6ntem sa\u011flayacak ve sa\u011flam bir teknik temel olu\u015fturacakt\u0131r.<\/p>","protected":false},"excerpt":{"rendered":"

Optimization of fresh cutting and processing technology for Alisma orientalis based on response surface methodology combined with overall evaluation normalization method Chinese herbal medicine Alisma orien tale (Sam.) Juzep. or Alisma plantago aquatica Linn. is a dried tuber of the plant Alisma orien tale (Sam.) in the family Alismataceae. It is included in the 2020 […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nOptimization of fresh cutting and processing technology for Alisma orientalis based on response surface methodology combined with overall evaluation normalization method - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/rhizoma-alismatis\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Optimization of fresh cutting and processing technology for Alisma orientalis based on response surface methodology combined with overall evaluation normalization method - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Optimization of fresh cutting and processing technology for Alisma orientalis based on response surface methodology combined with overall evaluation normalization method Chinese herbal medicine Alisma orien tale (Sam.) Juzep. or Alisma plantago aquatica Linn. is a dried tuber of the plant Alisma orien tale (Sam.) in the family Alismataceae. 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Juzep. or Alisma plantago aquatica Linn. is a dried tuber of the plant Alisma orien tale (Sam.) in the family Alismataceae. It is included in the 2020 […]","og_url":"https:\/\/longchangextracts.com\/tr\/rhizoma-alismatis\/","og_site_name":"China Chemical Manufacturer","article_published_time":"2024-08-04T18:56:29+00:00","og_image":[{"url":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-145.png"}],"author":"longcha9","twitter_card":"summary_large_image","twitter_misc":{"Yazan:":"longcha9","Tahmini okuma s\u00fcresi":"12 dakika"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/longchangextracts.com\/rhizoma-alismatis\/","url":"https:\/\/longchangextracts.com\/rhizoma-alismatis\/","name":"Alisma orientalis i\u00e7in taze kesme ve i\u015fleme teknolojisinin genel de\u011ferlendirme normalle\u015ftirme y\u00f6ntemi ile birlikte yan\u0131t y\u00fczeyi metodolojisine dayal\u0131 optimizasyonu - \u00c7in Kimya \u00dcreticisi","isPartOf":{"@id":"https:\/\/longchangextracts.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/longchangextracts.com\/rhizoma-alismatis\/#primaryimage"},"image":{"@id":"https:\/\/longchangextracts.com\/rhizoma-alismatis\/#primaryimage"},"thumbnailUrl":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-145.png","datePublished":"2024-08-04T18:56:29+00:00","dateModified":"2024-08-04T18:56:29+00:00","author":{"@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869"},"breadcrumb":{"@id":"https:\/\/longchangextracts.com\/rhizoma-alismatis\/#breadcrumb"},"inLanguage":"tr","potentialAction":[{"@type":"ReadAction","target":["https:\/\/longchangextracts.com\/rhizoma-alismatis\/"]}]},{"@type":"ImageObject","inLanguage":"tr","@id":"https:\/\/longchangextracts.com\/rhizoma-alismatis\/#primaryimage","url":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-145.png","contentUrl":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-145.png"},{"@type":"BreadcrumbList","@id":"https:\/\/longchangextracts.com\/rhizoma-alismatis\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/longchangextracts.com\/"},{"@type":"ListItem","position":2,"name":"Optimization of fresh cutting and processing technology for Alisma orientalis based on response surface methodology combined with overall evaluation normalization method"}]},{"@type":"WebSite","@id":"https:\/\/longchangextracts.com\/#website","url":"https:\/\/longchangextracts.com\/","name":"\u00c7in Kimyasal \u00dcreticisi","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/longchangextracts.com\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"tr"},{"@type":"Person","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869","name":"longcha9","image":{"@type":"ImageObject","inLanguage":"tr","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","caption":"longcha9"}}]}},"_links":{"self":[{"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/posts\/5422"}],"collection":[{"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/comments?post=5422"}],"version-history":[{"count":1,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/posts\/5422\/revisions"}],"predecessor-version":[{"id":5434,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/posts\/5422\/revisions\/5434"}],"wp:attachment":[{"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/media?parent=5422"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/categories?post=5422"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/tags?post=5422"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}