{"id":5377,"date":"2024-08-04T18:38:02","date_gmt":"2024-08-04T18:38:02","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5377"},"modified":"2024-08-04T18:38:02","modified_gmt":"2024-08-04T18:38:02","slug":"lamiophlomis","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/lamiophlomis\/","title":{"rendered":"Angelica sinensis'ten elde edilen toplam flavonoidlerin anti romatoid artritteki anahtar bile\u015fenlerinin spektral etki ili\u015fkisi ve bile\u015fen nakavt\u0131na dayal\u0131 olarak ara\u015ft\u0131r\u0131lmas\u0131"},"content":{"rendered":"

Angelica sinensis'ten elde edilen toplam flavonoidlerin anti romatoid artritteki anahtar bile\u015fenlerinin spektral etki ili\u015fkisi ve bile\u015fen nakavt\u0131na dayal\u0131 olarak ara\u015ft\u0131r\u0131lmas\u0131
\nGeleneksel bir \u00c7in ilac\u0131 olan Lamiophlomis Herba (LH), Lamiaceae familyas\u0131ndan bir bitki olan Lamiophlomis rotata (Benth.) Kudo'nun kurutulmu\u015f toprak \u00fcst\u00fc k\u0131sm\u0131d\u0131r. Tibetliler taraf\u0131ndan yayg\u0131n olarak kullan\u0131lan \u015fifal\u0131 bir bitkidir ve ayn\u0131 zamanda geleneksel bir \u00c7in ilac\u0131 olarak da yayg\u0131n olarak kullan\u0131lmaktad\u0131r. \u00c7in Halk Cumhuriyeti Farmakopesi'nin 2020 bask\u0131s\u0131, kan dola\u015f\u0131m\u0131n\u0131 te\u015fvik etme, kanamay\u0131 durdurma, r\u00fczgar\u0131 giderme ve a\u011fr\u0131y\u0131 hafifletme etkilerine sahip oldu\u011funu belirtmektedir. D\u00fc\u015fme, romatizma ve sar\u0131 su hastal\u0131\u011f\u0131n\u0131n neden oldu\u011fu yaralanmalar\u0131 tedavi etmek i\u00e7in kullan\u0131labilir. Tibet t\u0131bb\u0131ndaki isimleri \"Daba\" ve \"Dabuba\" olup, \"Yue Wang Yao Jian\", \"Four Medical Classics\", \"Jing Zhu Ben Cao\" gibi Tibet t\u0131p eserlerinde kaydedilmi\u015ftir. \u015eimdiye kadar 1200 y\u0131ll\u0131k bir uygulama ge\u00e7mi\u015fine sahiptir; \"Jingzhu Bencao\", Du Yi Wei'nin \"sar\u0131 su hastal\u0131\u011f\u0131n\u0131n\" tedavisinde kullan\u0131labilece\u011fini g\u00f6steren \"Du Yi Wei'nin \u00f6z\u00fc kat\u0131la\u015ft\u0131rd\u0131\u011f\u0131n\u0131 ve sar\u0131 suyu y\u00f6nlendirdi\u011fini\" kaydeder. Klinik belirtilere g\u00f6re, Tibet t\u0131bb\u0131nda kaydedilen \"sar\u0131 su hastal\u0131\u011f\u0131\" geleneksel \u00c7in t\u0131bb\u0131nda \"bi sendromu\" olarak s\u0131n\u0131fland\u0131r\u0131labilir. \"Bi sendromu \"ndan geli\u015fen \"kemik bi\" ve \"li jie hastal\u0131\u011f\u0131\", modern t\u0131ptaki \"romatoid artrit (RA) \"in klinik \u00f6zellikleriyle daha yak\u0131ndan ili\u015fkilidir. Bu nedenle, Du Yi Wei RA'y\u0131 tedavi etme potansiyeline sahiptir ve mevcut ara\u015ft\u0131rmalar da Du Yi Wei'nin RA kar\u015f\u0131t\u0131 etkileri oldu\u011funu g\u00f6stermi\u015ftir.
\nRA, kronik ve \u00e7oklu eklem iltihaplar\u0131 ile karakterize otoimm\u00fcn bir hastal\u0131kt\u0131r. Patolojik \u00f6zellikleri aras\u0131nda sinovyal h\u00fccrelerin t\u00fcm\u00f6r benzeri proliferasyonu ve vask\u00fcler opasitelerin olu\u015fumu yer almakta olup, fibroblast benzeri sinoviyositler (FLS) ana efekt\u00f6r h\u00fccreleridir. G\u00fcn\u00fcm\u00fczde RA'n\u0131n patogenezi hala belirsizdir. G\u00f6r\u00fclme s\u0131kl\u0131\u011f\u0131 ve sakatl\u0131k oran\u0131 y\u00fcksektir ve genellikle gizli seyreder. Hastal\u0131\u011f\u0131n ge\u00e7 evresi, D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc taraf\u0131ndan belirtilen modern bir refrakter hastal\u0131k olan farkl\u0131 derecelerde geri d\u00f6n\u00fc\u015f\u00fcms\u00fcz sakatl\u0131\u011fa yol a\u00e7abilir. Klinik uygulamada RA tedavisinde yayg\u0131n olarak kullan\u0131lan kimyasal ila\u00e7lar aras\u0131nda nonsteroid antienflamatuvar ila\u00e7lar, imm\u00fcnosupresanlar, glukokortikoidler ve biyolojikler yer almaktad\u0131r. \u0130lk \u00fc\u00e7 kimyasal ila\u00e7 \u00f6nemli yan etkilere sahipken, biyolojik ila\u00e7lar\u0131n pahal\u0131 fiyat\u0131 uzun s\u00fcreli uygulamalar\u0131n\u0131 s\u0131n\u0131rlamaktad\u0131r. Bu nedenle, d\u00fc\u015f\u00fck yan etkileri ve stabil terap\u00f6tik etkileri olan yeni klinik anti RA ila\u00e7lar\u0131n\u0131n geli\u015ftirilmesi \u00f6zellikle gereklidir.
\nAra\u015ft\u0131rma grubu, Du Yi Wei'nin RA tedavisindeki farmakolojik madde temelini ve etki mekanizmas\u0131n\u0131 ke\u015ffetmek i\u00e7in ilk kez a\u011f farmakolojisini kulland\u0131. Du Yi Wei'nin RA \u00fczerindeki terap\u00f6tik etkisinin, flavonoidlerin yakla\u015f\u0131k 40%'yi olu\u015fturdu\u011fu 23 bile\u015feniyle ili\u015fkili oldu\u011fu bulunmu\u015ftur; bu da flavonoidlerin, \u00f6zellikle luteolin olmak \u00fczere Du Yi Wei'nin anti RA s\u00fcrecinde \u00f6nemli bir rol oynad\u0131\u011f\u0131n\u0131 g\u00f6stermektedir; Du Yi Wei'nin anti RA etkisinin ana mekanizmas\u0131n\u0131n, PI3K Akt sinyal yolunu inhibe ederek sinovyal h\u00fccrelerin apoptozunu ind\u00fcklemek olabilece\u011fi \u00f6nerilmektedir. Bu arada, Du Yi Wei'nin anti RA etkisi ve farmakolojik madde temeli bir s\u0131\u00e7an adjuvan artrit modeli ile incelenmi\u015f ve sonu\u00e7lar Du Yi Wei'nin toplam flavonoidlerinin iyi anti RA etkilerine sahip oldu\u011funu g\u00f6stermi\u015ftir. Du Yi Wei'nin toplam flavonoidleri anti RA etkisi i\u00e7in ana farmakolojik maddelerden biri olabilir, ancak Du Yi Wei toplam flavonoidlerindeki anahtar anti RA bile\u015fenleri hala belirsizdir ve daha fazla ara\u015ft\u0131rma gerektirir. Bu nedenle, bu \u00e7al\u0131\u015fma, Angelica sinensis'in RA tedavisinde klinik uygulamas\u0131 i\u00e7in teorik temel ve referans sa\u011flamak amac\u0131yla, spektral etki ili\u015fkileri ve bile\u015fen nakavt teknikleri yoluyla Angelica sinensis'in toplam flavonoidlerindeki temel anti RA bile\u015fenlerini ara\u015ft\u0131rmay\u0131 ama\u00e7lamaktad\u0131r.<\/p>\n

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Tart\u0131\u015fma ve Sonu\u00e7
\nAngelica sinensis'teki toplam flavonoidlerin parmak izi \u00fczerine bir \u00f6n \u00e7al\u0131\u015fma, diyot dizi dedekt\u00f6rl\u00fc y\u00fcksek performansl\u0131 s\u0131v\u0131 kromatografisi (HPLC-DAD) kullan\u0131larak ger\u00e7ekle\u015ftirilmi\u015ftir. Angelica sinensis toplam flavonoid \u00f6rneklerinin her bir partisinin parmak izi spektrumlar\u0131 ile belirlenen kontrol parmak izi spektrumlar\u0131 aras\u0131ndaki benzerlik 0,9'dan b\u00fcy\u00fckt\u00fc ve bu da Angelica sinensis toplam flavonoid \u00f6rneklerinin farkl\u0131 partilerinde bulunan kimyasal bile\u015fenlerin tutarl\u0131 oldu\u011funu g\u00f6steriyordu. Ara\u015ft\u0131rma grubu, Angelica sinensis'teki toplam flavonoidlerin farkl\u0131 konsantrasyonlar\u0131n\u0131n ve uygulama s\u00fcrelerinin erken a\u015famada FLS h\u00fccre canl\u0131l\u0131\u011f\u0131 \u00fczerindeki etkilerini ara\u015ft\u0131rm\u0131\u015ft\u0131r. Buna dayanarak, Angelica sinensis'teki farkl\u0131 toplam flavonoid partilerinin FLS h\u00fccre canl\u0131l\u0131\u011f\u0131 \u00fczerindeki etkilerini ara\u015ft\u0131rmak i\u00e7in FLS h\u00fccrelerini 48 saat boyunca 64 \u03bcg\/mL konsantrasyonda tedavi etmek i\u00e7in CCK-8 y\u00f6ntemi kullan\u0131lm\u0131\u015ft\u0131r. Sonu\u00e7lar, Angelica sinensis'teki toplam flavonoidlerin 13 partisinin t\u00fcm\u00fcn\u00fcn FLS h\u00fccre canl\u0131l\u0131\u011f\u0131n\u0131 \u00f6nemli \u00f6l\u00e7\u00fcde inhibe edebildi\u011fini g\u00f6stermi\u015ftir. Angelica sinensis'teki toplam flavonoidlerin parmak izi spektrumuna ve h\u00fccre etkinli\u011fi deneylerinin sonu\u00e7lar\u0131na dayanarak, Angelica sinensis'teki toplam flavonoidlerin RA'ya kar\u015f\u0131 spektrum etki ili\u015fkisini kurmak i\u00e7in gri ili\u015fkisel analiz ve k\u0131smi en k\u00fc\u00e7\u00fck kareler (PLS) regresyon analizi kullan\u0131lm\u0131\u015ft\u0131r. Sonu\u00e7lar, Angelica sinensis'in toplam flavonoidleri i\u00e7indeki verbascoside ve verbascoside bile\u015fenlerinin anti RA etkinli\u011finde \u00f6nemli bir rol oynad\u0131\u011f\u0131n\u0131 g\u00f6stermi\u015ftir. \u0130nce tabaka kromatografisine dayanarak, Angelica sinensis'in toplam flavonoidlerindeki y\u00fcksek verbascoside i\u00e7eri\u011fi etkili bir \u015fekilde elimine edildi ve her bir numunenin FLS h\u00fccre canl\u0131l\u0131\u011f\u0131 \u00fczerindeki etkisi CCK-8 y\u00f6ntemi ile belirlendi. Sonu\u00e7lar, t\u00fcm bile\u015fen ve hedef bile\u015fen \u00f6rneklerinin FLS h\u00fccre canl\u0131l\u0131\u011f\u0131n\u0131 \u00f6nemli \u00f6l\u00e7\u00fcde inhibe edebildi\u011fini, hedef negatif bile\u015fen \u00f6rne\u011finin ise FLS h\u00fccre canl\u0131l\u0131\u011f\u0131 \u00fczerinde \u00f6nemli bir inhibit\u00f6r etkisi olmad\u0131\u011f\u0131n\u0131 g\u00f6stermi\u015ftir. Ayn\u0131 zamanda, e\u015fit miktarda verbascoside ve verbascoside'in RA-FLS h\u00fccrelerinin canl\u0131l\u0131\u011f\u0131 \u00fczerindeki etkileri kar\u015f\u0131la\u015ft\u0131r\u0131lm\u0131\u015ft\u0131r. Sonu\u00e7lar, hem verbascoside hem de verbascoside'\u0131n FLS h\u00fccrelerinin canl\u0131l\u0131\u011f\u0131n\u0131 \u00f6nemli \u00f6l\u00e7\u00fcde inhibe edebildi\u011fini, ancak verbascoside grubu ile verbascoside grubu aras\u0131nda \u00f6nemli bir fark olmad\u0131\u011f\u0131n\u0131 g\u00f6stermi\u015ftir.
\n\u00d6zetle, bu \u00e7al\u0131\u015fman\u0131n sonu\u00e7lar\u0131 verbascoside ve verbascoside bile\u015fenlerinin Angelica sinensis'teki toplam flavonoidlerin anti RA etkinli\u011finde \u00f6nemli bir rol oynad\u0131\u011f\u0131n\u0131 g\u00f6stermektedir. Angelica sinensis'teki toplam flavonoidlerin parmak izi analizi ile birle\u015ftirildi\u011finde, verbascoside i\u00e7eri\u011finin verbascoside i\u00e7eri\u011finden \u00f6nemli \u00f6l\u00e7\u00fcde daha y\u00fcksek oldu\u011fu ve verbascoside'in (C21H20O11) anti RA i\u00e7in Angelica sinensis'teki toplam flavonoidlerin anahtar bile\u015feni oldu\u011funu g\u00f6stermektedir. RA tedavisinde Du Yi Wei'den elde edilen toplam flavonoidlerin klinik uygulamas\u0131 i\u00e7in bilimsel bir temel sa\u011flayabilir. Osmanthus glikozitleri \u00e7e\u015fitli t\u0131bbi bitkilerde yayg\u0131n olarak bulunur ve minimum toksik yan etkilerle birlikte anti-enflamatuar, antioksidan, antikanser ve hipoglisemik y\u00f6nlerden \u00f6nemli etkilere sahiptir. Verbascoside bile\u015fenleri nispeten yayg\u0131n olmas\u0131na ra\u011fmen, \u015fu anda verbascoside'in anti RA etkileri hakk\u0131nda literat\u00fcr eksikli\u011fi bulunmaktad\u0131r. Bu \u00e7al\u0131\u015fmada, verbascoside'in RA-FLS h\u00fccre canl\u0131l\u0131\u011f\u0131 \u00fczerindeki etkisini ara\u015ft\u0131rmak i\u00e7in CCK-8 y\u00f6ntemi kullan\u0131lm\u0131\u015f ve verbascoside'in FLS h\u00fccre canl\u0131l\u0131\u011f\u0131 \u00fczerinde inhibe edici bir etkiye sahip oldu\u011fu a\u00e7\u0131k\u00e7a g\u00f6sterilmi\u015ftir. Daha sonra, in vivo etkinlik do\u011frulamas\u0131 i\u00e7in bir s\u0131\u00e7an artrit modeli olu\u015fturulabilir ve etki yolu a\u00e7\u0131klanabilir, b\u00f6ylece RA tedavisinde Angelica sinensis'in toplam flavonoidlerinin klinik kullan\u0131m\u0131 i\u00e7in daha fazla referans ve temel sa\u011flanabilir.<\/p>","protected":false},"excerpt":{"rendered":"

Exploring the key components of total flavonoids from Angelica sinensis in anti rheumatoid arthritis based on spectral effect relationship and component knockout Lamiophlomis Herba (LH), a traditional Chinese medicine, is the dried aboveground part of Lamiophlomis rotata (Benth.) Kudo, a plant in the family Lamiaceae. It is a medicinal herb commonly used by Tibetans and […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nExploring the key components of total flavonoids from Angelica sinensis in anti rheumatoid arthritis based on spectral effect relationship and component knockout - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/lamiophlomis\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Exploring the key components of total flavonoids from Angelica sinensis in anti rheumatoid arthritis based on spectral effect relationship and component knockout - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Exploring the key components of total flavonoids from Angelica sinensis in anti rheumatoid arthritis based on spectral effect relationship and component knockout Lamiophlomis Herba (LH), a traditional Chinese medicine, is the dried aboveground part of Lamiophlomis rotata (Benth.) Kudo, a plant in the family Lamiaceae. It is a medicinal herb commonly used by Tibetans and […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/longchangextracts.com\/tr\/lamiophlomis\/\" \/>\n<meta property=\"og:site_name\" content=\"China Chemical Manufacturer\" \/>\n<meta property=\"article:published_time\" content=\"2024-08-04T18:38:02+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-140.png\" \/>\n<meta name=\"author\" content=\"longcha9\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Yazan:\" \/>\n\t<meta name=\"twitter:data1\" content=\"longcha9\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tahmini okuma s\u00fcresi\" \/>\n\t<meta name=\"twitter:data2\" content=\"8 dakika\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/longchangextracts.com\/lamiophlomis\/\",\"url\":\"https:\/\/longchangextracts.com\/lamiophlomis\/\",\"name\":\"Exploring the key components of total flavonoids from Angelica sinensis in anti rheumatoid arthritis based on spectral effect relationship and component knockout - China Chemical Manufacturer\",\"isPartOf\":{\"@id\":\"https:\/\/longchangextracts.com\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/longchangextracts.com\/lamiophlomis\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/longchangextracts.com\/lamiophlomis\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-140.png\",\"datePublished\":\"2024-08-04T18:38:02+00:00\",\"dateModified\":\"2024-08-04T18:38:02+00:00\",\"author\":{\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\"},\"breadcrumb\":{\"@id\":\"https:\/\/longchangextracts.com\/lamiophlomis\/#breadcrumb\"},\"inLanguage\":\"tr\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/longchangextracts.com\/lamiophlomis\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"tr\",\"@id\":\"https:\/\/longchangextracts.com\/lamiophlomis\/#primaryimage\",\"url\":\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-140.png\",\"contentUrl\":\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-140.png\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/longchangextracts.com\/lamiophlomis\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/longchangextracts.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Exploring the key components of total flavonoids from Angelica sinensis in anti rheumatoid arthritis based on spectral effect relationship and component knockout\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/longchangextracts.com\/#website\",\"url\":\"https:\/\/longchangextracts.com\/\",\"name\":\"China Chemical Manufacturer\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/longchangextracts.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"tr\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\",\"name\":\"longcha9\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"tr\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"caption\":\"longcha9\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Anti romatoid artritte Angelica sinensis'ten elde edilen toplam flavonoidlerin anahtar bile\u015fenlerinin spektral etki ili\u015fkisi ve bile\u015fen nakavt\u0131na dayal\u0131 olarak ara\u015ft\u0131r\u0131lmas\u0131 - \u00c7in Kimya \u00dcreticisi","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/longchangextracts.com\/tr\/lamiophlomis\/","og_locale":"tr_TR","og_type":"article","og_title":"Exploring the key components of total flavonoids from Angelica sinensis in anti rheumatoid arthritis based on spectral effect relationship and component knockout - China Chemical Manufacturer","og_description":"Exploring the key components of total flavonoids from Angelica sinensis in anti rheumatoid arthritis based on spectral effect relationship and component knockout Lamiophlomis Herba (LH), a traditional Chinese medicine, is the dried aboveground part of Lamiophlomis rotata (Benth.) Kudo, a plant in the family Lamiaceae. It is a medicinal herb commonly used by Tibetans and […]","og_url":"https:\/\/longchangextracts.com\/tr\/lamiophlomis\/","og_site_name":"China Chemical Manufacturer","article_published_time":"2024-08-04T18:38:02+00:00","og_image":[{"url":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-140.png"}],"author":"longcha9","twitter_card":"summary_large_image","twitter_misc":{"Yazan:":"longcha9","Tahmini okuma s\u00fcresi":"8 dakika"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/longchangextracts.com\/lamiophlomis\/","url":"https:\/\/longchangextracts.com\/lamiophlomis\/","name":"Anti romatoid artritte Angelica sinensis'ten elde edilen toplam flavonoidlerin anahtar bile\u015fenlerinin spektral etki ili\u015fkisi ve bile\u015fen nakavt\u0131na dayal\u0131 olarak ara\u015ft\u0131r\u0131lmas\u0131 - \u00c7in Kimya \u00dcreticisi","isPartOf":{"@id":"https:\/\/longchangextracts.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/longchangextracts.com\/lamiophlomis\/#primaryimage"},"image":{"@id":"https:\/\/longchangextracts.com\/lamiophlomis\/#primaryimage"},"thumbnailUrl":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-140.png","datePublished":"2024-08-04T18:38:02+00:00","dateModified":"2024-08-04T18:38:02+00:00","author":{"@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869"},"breadcrumb":{"@id":"https:\/\/longchangextracts.com\/lamiophlomis\/#breadcrumb"},"inLanguage":"tr","potentialAction":[{"@type":"ReadAction","target":["https:\/\/longchangextracts.com\/lamiophlomis\/"]}]},{"@type":"ImageObject","inLanguage":"tr","@id":"https:\/\/longchangextracts.com\/lamiophlomis\/#primaryimage","url":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-140.png","contentUrl":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-140.png"},{"@type":"BreadcrumbList","@id":"https:\/\/longchangextracts.com\/lamiophlomis\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/longchangextracts.com\/"},{"@type":"ListItem","position":2,"name":"Exploring the key components of total flavonoids from Angelica sinensis in anti rheumatoid arthritis based on spectral effect relationship and component knockout"}]},{"@type":"WebSite","@id":"https:\/\/longchangextracts.com\/#website","url":"https:\/\/longchangextracts.com\/","name":"\u00c7in Kimyasal \u00dcreticisi","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/longchangextracts.com\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"tr"},{"@type":"Person","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869","name":"longcha9","image":{"@type":"ImageObject","inLanguage":"tr","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","caption":"longcha9"}}]}},"_links":{"self":[{"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/posts\/5377"}],"collection":[{"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/comments?post=5377"}],"version-history":[{"count":1,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/posts\/5377\/revisions"}],"predecessor-version":[{"id":5389,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/posts\/5377\/revisions\/5389"}],"wp:attachment":[{"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/media?parent=5377"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/categories?post=5377"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/tags?post=5377"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}