{"id":5266,"date":"2024-08-04T18:04:48","date_gmt":"2024-08-04T18:04:48","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5266"},"modified":"2024-08-04T18:04:48","modified_gmt":"2024-08-04T18:04:48","slug":"angiosperm-phylogeny-group","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/angiosperm-filogenisi-grubu\/","title":{"rendered":"UPLC-Q-TOF\/MS2 kombinasyon teknolojisine dayal\u0131 olarak Acorus cinsi geleneksel \u00c7in t\u0131bb\u0131nda 7H-azulene [1,2,3-i, j] isoquinolin-7-one bile\u015fenlerinin analizi"},"content":{"rendered":"

UPLC-Q-TOF\/MS2 kombinasyon teknolojisine dayal\u0131 olarak Acorus cinsi geleneksel \u00c7in t\u0131bb\u0131nda 7H-azulene [1,2,3-i, j] isoquinolin-7-one bile\u015fenlerinin analizi
\nAPG IV sistemi, Angiosperm Phylogeny Group (APG) taraf\u0131ndan olu\u015fturulan angiosperm s\u0131n\u0131fland\u0131rma sisteminin d\u00f6rd\u00fcnc\u00fc bask\u0131s\u0131d\u0131r. S\u0131n\u0131fland\u0131rma sistemi, Acorales'i orta angiospermlerde monokotiledon bitkilerin bir dal\u0131 olarak kabul eder ve monokotiledon bitkilerin en temel grubudur. Acorales alt\u0131nda yaln\u0131zca bir aile (Acoraceae) ve bir cins (Acorus) vard\u0131r ve yayg\u0131n bitkiler aras\u0131nda Acorus calamus L. ve Acorus tatarinowii Schott bulunur. \u00c7in Farmakopesi'nin 2020 bask\u0131s\u0131, her ikisi de Acori cinsinin \u015fifal\u0131 bitkileri olan Acori Tatarinowii Rhizome ve Acori Calami Rhizome'u i\u00e7ermektedir. Acori Calami Rhizome ad\u0131n\u0131 Tibet t\u0131bb\u0131ndaki kullan\u0131m\u0131ndan almaktad\u0131r ve orijinal bitkileri s\u0131ras\u0131yla A. tatarinowii Schott ve A. calamus L.'dir. Modern farmas\u00f6tik ara\u015ft\u0131rmalar, Acorus cinsinin geleneksel \u00c7in t\u0131bb\u0131n\u0131n \u00f6\u011frenme, haf\u0131za ve bili\u015fsel yetenekleri geli\u015ftirmede iyi etkileri oldu\u011funu g\u00f6stermi\u015ftir. Son y\u0131llarda, u\u00e7ucu ya\u011f, \u03b2 - asarone ve seskiterpenler gibi aktif bile\u015fenlere ek olarak, Acorus cinsinin geleneksel \u00c7in t\u0131bb\u0131nda iyi aktiviteye sahip alkaloidler de bulunmu\u015ftur. Lao ve arkada\u015flar\u0131 Acorus tatarinowii'den tatarin A, katarin B ve katarin C izole etmi\u015flerdir. Bunlar aras\u0131nda, bu \u00fc\u00e7 bile\u015feni i\u00e7eren Acorus tatarinowii'nin etil asetat ekstresi ve n-butanol ekstresi, skopolamin kaynakl\u0131 haf\u0131za bozuklu\u011fu modeli olan farelerin haf\u0131za bozuklu\u011funu \u00f6nemli \u00f6l\u00e7\u00fcde iyile\u015ftirebilir; Li ve ark. hasarl\u0131 sinir h\u00fccreleri \u00fczerinde iyi koruyucu etkileri olan Acorus calamus'tan Acorus calamus alkaloidleri A ve neo katarini izole etmi\u015ftir.
\nAcorus calamus alkaloidi yap\u0131sal olarak yeni bir tropoloizokinolin alkaloididir (TA), kimyasal ad\u0131 6-hidroksi-5,8-dimetoksi-7H-azuleno [1,2,3-i, j] izokinolin-7-on, j] izokinolin-7-on) \uff0c Temel ana \u00e7ekirde\u011fi 7H-azulen [1,2,3-i, j] isoquinolin-7-one (7H-azuleno [1,2,3-i, j] isoquinolin-7-one, 7H-AI7O olarak k\u0131salt\u0131l\u0131r, iskeleti \u015eekil 1'de g\u00f6sterilmi\u015ftir), Acorus calamus alkaloidi \u015fu anda do\u011fada bulunan 7H-AI7O yap\u0131sal ana \u00e7ekirde\u011fe sahip tek bile\u015fiktir. Bununla birlikte, bitkilerdeki Acorus calamus alkaloid miktar\u0131 son derece azd\u0131r ve 10 kg kurutulmu\u015f Acorus calamus k\u00f6k ve g\u00f6vdesinden sadece 5 mg izole edilmi\u015ftir. Bu nedenle, 7H-AI7O s\u0131n\u0131f\u0131 bile\u015fenlerin yap\u0131sal \u00f6zellikleri ve biyolojik aktivitesi g\u00f6z \u00f6n\u00fcne al\u0131nd\u0131\u011f\u0131nda, bu makale referans madde olarak Acorus calamus alkaloidlerini ve izleme nesnesi olarak 7H-AI7O s\u0131n\u0131f\u0131 bile\u015fenleri kullanmakta ve ultra y\u00fcksek performansl\u0131 s\u0131v\u0131 kromatografisini benimsemektedir. UPLC-Q-TOF\/MS2 tandem quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF\/MS2) teknolojisi, Acorus cinsinin geleneksel \u00c7in t\u0131bb\u0131ndaki 7H-AI7O s\u0131n\u0131f\u0131 bile\u015fenlerin bile\u015fimini ve da\u011f\u0131l\u0131m\u0131n\u0131 h\u0131zl\u0131 bir \u015fekilde izlemek ve tan\u0131mlamak i\u00e7in kullan\u0131l\u0131r. Bu, bu bile\u015fenlerin bitki kaynaklar\u0131n\u0131n daha da zenginle\u015ftirilmesi ve ilgili ila\u00e7lar\u0131n geli\u015ftirilmesi i\u00e7in belirli bir deneysel temel sa\u011flar.<\/p>\n

 <\/p>\n

\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"angiosperm phylogeny group\u015eu anda, bu deneyde sadece 5 parti Tibet Acorus tatarinowii ve 5 parti Acorus tatarinowii toplanm\u0131\u015ft\u0131r, \u00f6rnek boyutlar\u0131 ve \u00fcretim alanlar\u0131 s\u0131n\u0131rl\u0131d\u0131r. Bununla birlikte, \u015fimdiye kadar toplanan \u00f6rneklere dayanarak yine de baz\u0131 bilgiler elde edilebilir. Hem Tibet Acorus tatarinowii hem de Acorus tatarinowii t\u0131bbi malzemeleri 7H-AI7O s\u0131n\u0131f\u0131 bile\u015fenler i\u00e7erir; 7H-AI7O bile\u015fenleri i\u00e7eren Tibet Acorus calamus, \u00fcretim alan\u0131nda Acorus tatarinowii'den daha yayg\u0131n olarak da\u011f\u0131t\u0131l\u0131r; Acorus tatarinowii'de bulunan 7H-AI7O bile\u015fiklerinin yap\u0131sal t\u00fcrleri Acorus tatarinowii'dekilerden daha bol miktarda bulunur, ancak ara\u015ft\u0131rma i\u00e7eri\u011fi hen\u00fcz tamamlanmam\u0131\u015ft\u0131r. Gelecekte, numune toplama kapsam\u0131n\u0131 geni\u015fletmeye, numune say\u0131lar\u0131n\u0131 biriktirmeye ve farkl\u0131 k\u00f6kenlerden Acorus tatarinowii'deki 7H-AI7O bile\u015fenlerinin da\u011f\u0131l\u0131m\u0131n\u0131 ve i\u00e7erik de\u011fi\u015fikliklerini kapsaml\u0131 ve sistematik olarak analiz etmeye devam edece\u011fiz; Tespit edilen bol miktarda 7H-AI7O s\u0131n\u0131f\u0131 bile\u015fen i\u00e7eren Acorus calamus t\u0131bbi malzemelerini sistematik olarak izole etmek, spesifik bile\u015fikler elde etmek, farkl\u0131 s\u00fcbstit\u00fcentlere sahip 7H-AI7O s\u0131n\u0131f\u0131 bile\u015fenlerin k\u00fctle spektrometresi veri taban\u0131n\u0131 daha da geli\u015ftirmek ve 7H-AI7O s\u0131n\u0131f\u0131 bile\u015fenlerin yap\u0131s\u0131n\u0131n h\u0131zl\u0131 ve do\u011fru tespiti ve belirlenmesi i\u00e7in deneysel temel sa\u011flamak.<\/p>\n

Bitkilerden elde edilen 7H-AI7O miktar\u0131 son derece azd\u0131r. \u00d6nceki deneyler, Acorus calamus alkaloidlerinin (7H-AI7O yap\u0131s\u0131) ve Acorus calamus alkaloid A'n\u0131n (AA yap\u0131s\u0131) Acorus calamus'tan ayn\u0131 anda izole edilebilece\u011fini bulmu\u015ftur. Bu iki bile\u015fik aras\u0131ndaki yap\u0131sal fark, esas olarak ilkinin 7. pozisyonda ek bir karbonil grubuna sahip olmas\u0131nda yatmaktad\u0131r. CO kaybetmeye ve [M+H-28]+ olu\u015fturmaya e\u011filimli 7H-AI7O bile\u015fenlerinin \u00e7atlama \u00f6zellikleri ile birlikte, bitkilerde 7H-AI7O ve AA bile\u015fenleri aras\u0131nda bir biyotransformasyon ili\u015fkisi olabilece\u011fi tahmin edilmektedir. Bu nedenle, gelecekteki ara\u015ft\u0131rmalar Acorus \u00c7in t\u0131bb\u0131ndaki 7H-AI7O ve AA bile\u015fenleri aras\u0131ndaki biyotransformasyon ili\u015fkisinin yan\u0131 s\u0131ra toprak, iklim ve di\u011fer fakt\u00f6rlerin bitkilerdeki 7H-AI7O bile\u015fenlerinin biyosentezi \u00fczerindeki etkisini de ara\u015ft\u0131racakt\u0131r. Acorus cinsindeki geleneksel \u00c7in t\u0131bb\u0131n\u0131n delikleri a\u00e7mak, balgam\u0131 gidermek, zihni uyand\u0131rmak ve zekay\u0131 geli\u015ftirmek i\u00e7in maddi temelini daha fazla ara\u015ft\u0131rmak i\u00e7in deneysel kan\u0131t sa\u011flamak.<\/p>","protected":false},"excerpt":{"rendered":"

Analysis of the components of 7H-azulene [1,2,3-i, j] isoquinolin-7-one in Acorus genus traditional Chinese medicine based on UPLC-Q-TOF\/MS2 combination technology The APG IV system is the fourth edition of the angiosperm classification system established by the Angiosperm Phylogeny Group (APG). The classification system considers Acorales to be a branch of monocotyledonous plants in the middle […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nAnalysis of the components of 7H-azulene [1,2,3-i, j] isoquinolin-7-one in Acorus genus traditional Chinese medicine based on UPLC-Q-TOF\/MS2 combination technology - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/angiosperm-filogenisi-grubu\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Analysis of the components of 7H-azulene [1,2,3-i, j] isoquinolin-7-one in Acorus genus traditional Chinese medicine based on UPLC-Q-TOF\/MS2 combination technology - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Analysis of the components of 7H-azulene [1,2,3-i, j] isoquinolin-7-one in Acorus genus traditional Chinese medicine based on UPLC-Q-TOF\/MS2 combination technology The APG IV system is the fourth edition of the angiosperm classification system established by the Angiosperm Phylogeny Group (APG). 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