{"id":5191,"date":"2024-08-04T17:45:17","date_gmt":"2024-08-04T17:45:17","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5191"},"modified":"2024-08-04T17:45:17","modified_gmt":"2024-08-04T17:45:17","slug":"chaihu-and-baishao","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/chaihu-ve-baishao\/","title":{"rendered":"Uyumluluk \u00f6ncesi ve sonras\u0131nda Chaihu ve Baishao'nun u\u00e7ucu bile\u015fenlerindeki de\u011fi\u015fikliklerin HS-SPME-GC-MS analizi"},"content":{"rendered":"<p>Uyumluluk \u00f6ncesi ve sonras\u0131nda Chaihu ve Baishao'nun u\u00e7ucu bile\u015fenlerindeki de\u011fi\u015fikliklerin HS-SPME-GC-MS analizi<br \/>\nGeleneksel \u00c7in t\u0131bb\u0131 \u00e7iftleri re\u00e7eteli ila\u00e7lar\u0131n en k\u00fc\u00e7\u00fck birimidir ve ila\u00e7 \u00e7iftlerinin uyumlulu\u011fu temel olarak ayn\u0131 qi'yi arama, birbirini tamamlama, birbirine kar\u015f\u0131t olma ve ayn\u0131 sistemi kullanma kurallar\u0131n\u0131 izler. Beyaz \u015fakay\u0131k karaci\u011feri besler ve yumu\u015fat\u0131rken, Chaihu karaci\u011feri rahatlat\u0131r ve depresyonu hafifletir. \u0130ki bitkinin kombinasyonu karaci\u011fer qi'sinin geli\u015fimini destekler, kan\u0131 besler ve karaci\u011feri yumu\u015fat\u0131r. Beyaz \u015fakay\u0131k ve Chaihu birbirini tamamlar ve tamamlay\u0131c\u0131 bir ili\u015fkiye sahiptir. Beyaz \u015fakay\u0131k kan\u0131 besleyerek Chaihu'nun \u00e7ok fazla da\u011f\u0131lmas\u0131n\u0131 ve karaci\u011fer yinine zarar vermesini \u00f6nler. Chaihu tozu beyaz \u015fakay\u0131\u011f\u0131n ek\u015fi ve so\u011fuk olmas\u0131n\u0131 ve karaci\u011fer qi durgunlu\u011funu \u00f6nler. Hem karaci\u011feri yat\u0131\u015ft\u0131rmak hem de depresyonu hafifletmek, birbirlerinin g\u00fc\u00e7l\u00fc ve zay\u0131f y\u00f6nlerini tamamlayarak kar\u015f\u0131l\u0131kl\u0131 yard\u0131m gerektirir. Bu iki ila\u00e7 birle\u015ftirilerek Xiaoyao San, Sini San, Dachaihu Tang, Chaihu Shugan San gibi form\u00fcller olu\u015fturulur. Bupleurum chinense, Bupleurum chinense DC. veya Bupleurum scorzonerifolium Willd. \u015femsiye familyas\u0131 bitkisinin kurutulmu\u015f k\u00f6k\u00fcd\u00fcr. Beyaz \u015fakay\u0131k, Ranunculaceae familyas\u0131ndan bir bitki olan Paeonia lactiflora Pall. bitkisinin kurutulmu\u015f k\u00f6k\u00fcd\u00fcr. \u0130lgili literat\u00fcr incelendi\u011finde, \u00f6nceki \u00e7al\u0131\u015fmalarda Bupleurum chinense ve Paeonia lactiflora'n\u0131n u\u00e7ucu bile\u015fenlerini analiz etmek i\u00e7in gaz kromatografisi-k\u00fctle spektrometresi (GC-MS) kullan\u0131ld\u0131\u011f\u0131 g\u00f6r\u00fclm\u00fc\u015ft\u00fcr. Ancak, bug\u00fcne kadar, Bupleurum chinense ve Paeonia lactiflora'n\u0131n u\u00e7ucu bile\u015fenlerini uyumluluk \u00f6ncesi ve sonras\u0131nda analiz etmek i\u00e7in gaz kromatografisi-k\u00fctle spektrometresi (GC-MS) ile birlikte tepe bo\u015flu\u011fu kat\u0131 faz mikro ekstraksiyonunun (HS-SPME) kullan\u0131m\u0131na ili\u015fkin herhangi bir rapor bulunmamaktad\u0131r. HS-SPME yayg\u0131n olarak kullan\u0131lmaktad\u0131r ve y\u00fcksek verimlilik ve kolayl\u0131k \u00f6zelliklerine sahiptir. Bu \u00e7al\u0131\u015fmada, Chaihu ve Baishao'nun u\u00e7ucu bile\u015fenlerini ve bunlar\u0131n uyumluluk \u00f6ncesi ve sonras\u0131ndaki de\u011fi\u015fikliklerini ara\u015ft\u0131rmak i\u00e7in temel bile\u015fen analizi (PCA) ve di\u011fer veri analizi y\u00f6ntemleriyle birlikte HS-SPME-GC-MS teknolojisi kullan\u0131lm\u0131\u015f ve bu ilac\u0131n uyumluluk mekanizmas\u0131n\u0131n daha fazla ara\u015ft\u0131r\u0131lmas\u0131 i\u00e7in bir referans sa\u011flanm\u0131\u015ft\u0131r.<\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5192\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-125.png\" alt=\"\" width=\"785\" height=\"376\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-125.png 785w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-125-768x368.png 768w\" sizes=\"(max-width: 785px) 100vw, 785px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5193\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-111.png\" alt=\"\" width=\"784\" height=\"776\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-111.png 784w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-111-768x760.png 768w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-111-727x720.png 727w\" sizes=\"(max-width: 784px) 100vw, 784px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5194\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-105.png\" alt=\"\" width=\"786\" height=\"776\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-105.png 786w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-105-768x758.png 768w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-105-729x720.png 729w\" sizes=\"(max-width: 786px) 100vw, 786px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5195\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-94.png\" alt=\"\" width=\"784\" height=\"516\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-94.png 784w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-94-768x505.png 768w\" sizes=\"(max-width: 784px) 100vw, 784px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5196\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-86.png\" alt=\"\" width=\"358\" height=\"281\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5197\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-79.png\" alt=\"\" width=\"779\" height=\"289\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-79.png 779w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-79-768x285.png 768w\" sizes=\"(max-width: 779px) 100vw, 779px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5198\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-71.png\" alt=\"\" width=\"773\" height=\"144\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-71.png 773w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-71-768x143.png 768w\" sizes=\"(max-width: 773px) 100vw, 773px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5199\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-66.png\" alt=\"\" width=\"779\" height=\"312\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-66.png 779w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-66-768x308.png 768w\" sizes=\"(max-width: 779px) 100vw, 779px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5200\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-60.png\" alt=\"\" width=\"777\" height=\"151\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-60.png 777w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-60-768x149.png 768w\" sizes=\"(max-width: 777px) 100vw, 777px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5201\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-2.jpg\" alt=\"\" width=\"707\" height=\"262\" \/><br \/>\nBu \u00e7al\u0131\u015fmada Chaihu, Paeonia lactiflora ve Chaihu Paeonia lactiflora t\u0131bbi \u00e7iftlerinin u\u00e7ucu bile\u015fenlerini belirlemek ve analiz etmek i\u00e7in HS-SPME-GC-MS y\u00f6ntemi kullan\u0131lm\u0131\u015ft\u0131r. Chaihu Paeonia lactiflora 16 benzersiz u\u00e7ucu bile\u015fene, Chaihu ile 27 ortak u\u00e7ucu bile\u015fene ve Paeonia lactiflora ile 7 ortak u\u00e7ucu bile\u015fene sahiptir.<\/p>\n<p>T\u0131bbi bitkinin u\u00e7ucu bile\u015fen i\u00e7eri\u011fi tek bir bitkininki ile kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda, t\u0131bbi bitkide tek bir bitkiye k\u0131yasla u\u00e7ucu bile\u015fen i\u00e7eri\u011fi artan 15 bile\u015fen oldu\u011fu sonucuna var\u0131labilir; bunlar aras\u0131nda \u03b1 - zerde\u00e7al, \u03b2 - m\u00fcr, oksitlenmi\u015f karyofilen, soforid, (+) - \u03b2 - selvi terpenler, vb. yer almaktad\u0131r. \u0130la\u00e7ta, dodekan, benzil alkol, hekzadekan, nonadekan vb. dahil olmak \u00fczere tek bitkilere k\u0131yasla daha d\u00fc\u015f\u00fck u\u00e7ucu bile\u015fen i\u00e7eri\u011fine sahip 15 bile\u015fen bulunmaktad\u0131r. Ayn\u0131 zamanda, ilaca verbenon, trans karyofilen, \u03b1 - kumarin, valencene, prostaglandin E1, vb. dahil olmak \u00fczere 16 yeni u\u00e7ucu bile\u015fik eklenmi\u015ftir. Tek bitkilerle kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda, bitkideki (+) - \u03b2 - selvi terpenlerinin artan i\u00e7eri\u011fi, antibakteriyel, anti-inflamatuar, b\u00fcz\u00fcc\u00fc, idrar s\u00f6kt\u00fcr\u00fcc\u00fc, yumu\u015fat\u0131c\u0131, balgam s\u00f6kt\u00fcr\u00fcc\u00fc ve antifungal etkilere sahip Platycodon grandiflorus u\u00e7ucu ya\u011f\u0131n\u0131n ana bile\u015fenidir; \u03b1 - Curcumene g\u00fc\u00e7l\u00fc antibakteriyel aktiviteye sahiptir; \u03b2 - myrrhene bir\u00e7ok meme kanseri h\u00fccresini inhibe edebilir; Okside caryophyllene anti astmatik, anti-t\u00fcm\u00f6r, antibakteriyel ve \u00f6ks\u00fcr\u00fck kesici etkilere sahiptir. Ayr\u0131ca, trans karyofilen, alfa betel ya\u011f\u0131, prostaglandin E1 vb. gibi iki ilac\u0131n kombinasyonundan sonra yeni eklenen bile\u015fenler, trans karyofilen belirli anti astmatik ve antibakteriyel etkilere sahipken, \u00fcretilen alfa betel ya\u011f\u0131 iyi antibakteriyel etkilere sahiptir. Prostaglandin E1, Chaihu Baishao kombinasyonunun klinik uygulamas\u0131 ile tutarl\u0131 olan iyi anti-enflamatuar etkilere sahiptir. Ek olarak, ilac\u0131n dodekan gibi i\u00e7eri\u011fi azalt\u0131lm\u0131\u015f bile\u015fenlere kar\u015f\u0131 d\u00fc\u015f\u00fck toksisitesi vard\u0131r; Benzil alkol merkezi sinir sistemi i\u00e7in toksiktir; Hekzadekan buhar\u0131 insan v\u00fccudunun \u00fcst solunum yollar\u0131nda, g\u00f6zlerinde ve cildinde tahri\u015fe neden olabilir ve bu zararl\u0131 bile\u015fenlerin i\u00e7eri\u011fi iki ilac\u0131n kombinasyonundan sonra azal\u0131r. U\u00e7ucu bile\u015fenler a\u00e7\u0131s\u0131ndan bak\u0131ld\u0131\u011f\u0131nda, Chaihu ve Baishao kombinasyonunun toksisiteyi azaltma ve verimlili\u011fi art\u0131rma etkisine sahip oldu\u011fu sonucuna var\u0131labilir. \u00d6rne\u011fin, ana bile\u015fenleri Chaihu ve Baishao olan klasik \u00c7in t\u0131bb\u0131 preparat\u0131 Anru Xiaotong Wan, birlikte kullan\u0131ld\u0131\u011f\u0131nda, karaci\u011fer sorunlar\u0131n\u0131 tedavi etmek i\u00e7in sadece karaci\u011feri yat\u0131\u015ft\u0131rmak ve depresyonu hafifletmekle kalmaz, ayn\u0131 zamanda karaci\u011feri yumu\u015fat\u0131r ve karaci\u011fer v\u00fccudunu desteklemek i\u00e7in yin besler. Kan\u0131 besleyici, yini besleyici ve a\u011fr\u0131y\u0131 hafifletici etkiye sahiptir.<\/p>\n<p>Bir \u00e7al\u0131\u015fmada, Bupleurum chinense'nin u\u00e7ucu ya\u011f\u0131n\u0131 \u00e7\u0131karmak ve kimyasal bile\u015fenlerini niteliksel olarak tan\u0131mlamak i\u00e7in Soxhlet, mikrodalga, su distilasyonu ve s\u00fcperkritik CO2 buhar distilasyonu ekstraksiyon y\u00f6ntemleri kullan\u0131lm\u0131\u015ft\u0131r. Analizler sonucunda toplam 34, 21, 25 ve 19 u\u00e7ucu bile\u015fen tespit edilmi\u015ftir. Bu \u00e7al\u0131\u015fmada, Bupleurum chinense'nin 61 u\u00e7ucu bile\u015fenini ay\u0131rmak ve niteliksel olarak tan\u0131mlamak i\u00e7in HS-SPME kullan\u0131lm\u0131\u015ft\u0131r. HS-SPME-GC-MS kombine teknolojisinin kullan\u0131m\u0131, ila\u00e7lar\u0131n u\u00e7ucu bile\u015fenlerinin ekstraksiyon oran\u0131n\u0131 art\u0131rabilir. Literat\u00fcrde kullan\u0131lan y\u00f6ntemlerle kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda, ila\u00e7lar\u0131n pik say\u0131s\u0131 ve u\u00e7ucu madde i\u00e7eri\u011fi daha y\u00fcksektir, bu da tepe bo\u015flu\u011fu kat\u0131 faz mikroekstraksiyonunun ila\u00e7lar\u0131n u\u00e7ucu bile\u015fenlerini ekstrakte etmede y\u00fcksek verimlilik ve hassasiyete sahip oldu\u011funu g\u00f6stermektedir.<\/p>\n<p>\u00d6zetle, Chaihu ve Baishao kombinasyonu klinik uygulamada yayg\u0131n olarak kullan\u0131lmaktad\u0131r. Ancak Chaihu, Baishao ve ila\u00e7lar\u0131n\u0131n u\u00e7ucu bile\u015fenleri hakk\u0131nda \u00e7ok az ara\u015ft\u0131rma vard\u0131r. Bu deneyde Chaihu, Baishao ve Chaihu Baishao'nun u\u00e7ucu bile\u015fenlerini belirlemek i\u00e7in HS-SPME-GC-MS teknolojisi uygulanm\u0131\u015ft\u0131r. Her bir bile\u015fenin y\u00fczde i\u00e7eri\u011fi alan normalle\u015ftirme y\u00f6ntemi ile belirlenmi\u015ftir. U\u00e7ucu bile\u015fenler perspektifinden, Chaihu Baishao'nun uyumluluk \u00f6ncesi ve sonras\u0131 kimyasal bile\u015fimindeki de\u011fi\u015fiklikler analiz edilmi\u015ftir. Uyumluluk kurallar\u0131na dayanarak, Chaihu ara\u015ft\u0131r\u0131ld\u0131 m\u0131? Paeonia lactiflora \u015fifal\u0131 bitkilerinin uyumlulu\u011funun terap\u00f6tik mekanizmas\u0131n\u0131 daha fazla ara\u015ft\u0131rmak.<\/p>","protected":false},"excerpt":{"rendered":"<p>HS-SPME-GC-MS analysis of changes in volatile components of Chaihu and Baishao before and after compatibility Traditional Chinese medicine pairs are the smallest unit of prescription medication, and the compatibility of drug pairs mainly follows the rules of seeking the same qi, complementing each other, opposing each other, and using the same system. White peony nourishes [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>HS-SPME-GC-MS analysis of changes in volatile components of Chaihu and Baishao before and after compatibility - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/chaihu-ve-baishao\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HS-SPME-GC-MS analysis of changes in volatile components of Chaihu and Baishao before and after compatibility - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"HS-SPME-GC-MS analysis of changes in volatile components of Chaihu and Baishao before and after compatibility Traditional Chinese medicine pairs are the smallest unit of prescription medication, and the compatibility of drug pairs mainly follows the rules of seeking the same qi, complementing each other, opposing each other, and using the same system. 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