{"id":5167,"date":"2024-08-04T17:38:19","date_gmt":"2024-08-04T17:38:19","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5167"},"modified":"2024-08-04T17:38:19","modified_gmt":"2024-08-04T17:38:19","slug":"extensive-targeted-metabolomics","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/extensive-targeted-metabolomics\/","title":{"rendered":"Palmiye a\u011fa\u00e7lar\u0131n\u0131n farkl\u0131 k\u0131s\u0131mlar\u0131ndaki u\u00e7ucu metabolitlerdeki farkl\u0131l\u0131klar\u0131n kapsaml\u0131 hedefli metabolomiklere dayal\u0131 analizi"},"content":{"rendered":"

Palmiye a\u011fa\u00e7lar\u0131n\u0131n farkl\u0131 k\u0131s\u0131mlar\u0131ndaki u\u00e7ucu metabolitlerdeki farkl\u0131l\u0131klar\u0131n kapsaml\u0131 hedefli metabolomiklere dayal\u0131 analizi
\nOrmosia henryi, baklagiller familyas\u0131ndan, \u00e7o\u011funlukla \u00c7in'in subtropikal b\u00f6lgelerinde, \u00f6zellikle Jiangxi, Zhejiang, Anhui, Hubei, Hunan, Guangdong, Sichuan, Guizhou ve Yunnan gibi eyaletlerde da\u011f\u0131l\u0131m g\u00f6steren, yaprak d\u00f6kmeyen bir a\u011fa\u00e7t\u0131r. D\u00fc\u015f\u00fck tohum tutma oran\u0131, zay\u0131f do\u011fal yenilenme kabiliyeti ve insan tahribat\u0131 nedeniyle yabani kaynaklar\u0131 t\u00fckenmi\u015ftir ve tehlike alt\u0131ndad\u0131r. Ulusal ikinci s\u0131n\u0131f anahtar koruma bitkisi olarak listelenmi\u015ftir. Palmiye a\u011fac\u0131n\u0131n uzun bir a\u011fa\u00e7 \u015fekli, g\u00fczel ah\u015fap dokusu vard\u0131r ve k\u0131rm\u0131z\u0131 tohumlar\u0131 el sanatlar\u0131 olarak kullan\u0131labilir; Palmiye a\u011fac\u0131n\u0131n tamam\u0131, kan dola\u015f\u0131m\u0131n\u0131 te\u015fvik etme, kan staz\u0131n\u0131 giderme, r\u00fczgar\u0131 da\u011f\u0131tma ve \u015fi\u015fli\u011fi azaltma etkileri ile ila\u00e7 olarak kullan\u0131labilir. \"\u00c7in Bitkisel \u0130la\u00e7lar\u0131n\u0131n Ulusal Derlemesi\", palmiye a\u011fac\u0131n\u0131n k\u00f6k kabu\u011fundaki k\u0131r\u0131klar\u0131 ve yapraklar\u0131ndaki yan\u0131klar\u0131 tedavi etmek i\u00e7in harici olarak kullan\u0131ld\u0131\u011f\u0131n\u0131 kaydeder. Halk k\u00fclt\u00fcr\u00fcnde palmiye a\u011fac\u0131 genellikle sakinle\u015ftirici etkisi olan yatak tahtalar\u0131 yapmak i\u00e7in kullan\u0131l\u0131r. Bu nedenle palmiye a\u011fac\u0131 kereste, peyzaj ve t\u0131bbi kullan\u0131m\u0131 birle\u015ftiren e\u015fsiz ve de\u011ferli bir a\u011fa\u00e7 t\u00fcr\u00fcd\u00fcr.
\nBitkilerin u\u00e7ucu maddeleri deri ve solunum sistemi yoluyla insan v\u00fccuduna etki edebilir, merkezi sinir sistemini stabilize edebilir, duygular\u0131 d\u00fczenleyebilir, ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 art\u0131rabilir ve mikroorganizmalar\u0131n ve vir\u00fcslerin insan v\u00fccuduna verdi\u011fi zarar\u0131 etkili bir \u015fekilde azaltabilir. Modern ara\u015ft\u0131rmalar palmiye a\u011fa\u00e7lar\u0131n\u0131n esas olarak aldehitler, ketonlar, alkoller, esterler, olefinler, aminler, siklik hidrokarbonlar, karboksilik asitler ve amidler gibi 89 u\u00e7ucu bile\u015fen i\u00e7erdi\u011fini g\u00f6stermi\u015ftir. Bunlar aras\u0131nda, orman sa\u011fl\u0131\u011f\u0131, farmas\u00f6tik ve g\u00fcnl\u00fck kimyasal \u00fcr\u00fcnler ve di\u011fer alanlarda y\u00fcksek kullan\u0131m de\u011ferine sahip \u03b2 - karyofilen, limonen, \u03b2 - iyonon vb. faydal\u0131 bile\u015fenler bulunmaktad\u0131r. Buna ek olarak, ara\u015ft\u0131rmalar palmiye \u00f6z\u00fct\u00fcn\u00fcn merkezi sinir sistemi \u00fczerinde etkili olabilece\u011fini bulmu\u015ftur ve Lu ve ark. ilk olarak palmiye yapra\u011f\u0131 \u00f6z\u00fct\u00fcn\u00fcn \u00f6n antidepresan etkilere sahip oldu\u011funu \u00f6ne s\u00fcrm\u00fc\u015ft\u00fcr; Zhu, palmiye yapra\u011f\u0131 \u00f6z\u00fct\u00fcn\u00fcn antidepresan etkisini kronik \u00f6ng\u00f6r\u00fclemeyen hafif stres fare modeli kullanarak incelemi\u015f ve \u00f6nemli antidepresan etkilere sahip oldu\u011funu bulmu\u015ftur.
\nBitkilerdeki u\u00e7ucu bile\u015fenlerin bile\u015fimi doku k\u0131s\u0131mlar\u0131yla yak\u0131ndan ili\u015fkilidir. Tao ve arkada\u015flar\u0131, ah\u015fap kelebe\u011fin farkl\u0131 k\u0131s\u0131mlar\u0131ndaki u\u00e7ucu bile\u015fenleri analiz etmi\u015f ve hepsinin y\u00fcksek miktarda alkol maddesi i\u00e7erdi\u011fini ve her k\u0131sm\u0131n di\u011ferlerinden daha y\u00fcksek karakteristik maddelere sahip oldu\u011funu bulmu\u015ftur; Guo ve arkada\u015flar\u0131, han\u0131melinin alt\u0131n \u00e7i\u00e7ek k\u0131sm\u0131ndaki u\u00e7ucu bile\u015fenlerin \u00e7e\u015fitli oldu\u011funu, asetik asit, 2-metilbutanal veya 3-metilbutanal\u0131n her k\u0131s\u0131mda yayg\u0131n olarak bulunan bile\u015fenler oldu\u011funu bulmu\u015ftur. \u015eu anda, palmiye a\u011fa\u00e7lar\u0131n\u0131n k\u00f6kleri, dallar\u0131 ve yapraklar\u0131ndaki metabolit bile\u015fenlerinin kapsaml\u0131 analizi ve \u00fc\u00e7 k\u0131s\u0131m aras\u0131ndaki kompozisyon farkl\u0131l\u0131klar\u0131 hakk\u0131nda bir rapor bulunmamaktad\u0131r. \u00c7ok say\u0131da \u00e7al\u0131\u015fma, bitki u\u00e7ucular\u0131n\u0131n sa\u011fl\u0131\u011fa faydalar\u0131n\u0131n, palmiye a\u011fa\u00e7lar\u0131ndaki u\u00e7ucu bile\u015fiklerin ana bile\u015fenleri olan terpenlerin sal\u0131n\u0131m konsantrasyonuyla yak\u0131ndan ili\u015fkili oldu\u011funu g\u00f6stermi\u015ftir. Bu nedenle, palmiye a\u011fa\u00e7lar\u0131ndaki y\u00fcksek oranda zenginle\u015ftirilmi\u015f u\u00e7ucu bile\u015fenlerin kaz\u0131lmas\u0131 ve aktif bile\u015fenlerin (\u00f6zellikle terpenoidler) yo\u011funla\u015ft\u0131\u011f\u0131 b\u00f6lgelerin belirlenmesi, palmiye a\u011fac\u0131 kaynaklar\u0131n\u0131n geli\u015ftirilmesi ve kullan\u0131m\u0131 i\u00e7in b\u00fcy\u00fck \u00f6nem ta\u015f\u0131maktad\u0131r.
\nYayg\u0131n olarak hedeflenen metabolomik teknolojisi, biyolojik \u00f6rneklerdeki metabolitleri ve i\u00e7eriklerini y\u00fcksek hassasiyet, y\u00fcksek verim ve geni\u015f kapsama alan\u0131 ile tespit edebilir. Y\u00fcksek verimli alg\u0131lama ve veri i\u015fleme yoluyla, biyolojik \u00f6rneklerdeki metabolitlerin de\u011fi\u015fikliklerini ve farkl\u0131 ortamlara, d\u00f6nemlere ve d\u0131\u015f uyaranlara tepkilerini ortaya \u00e7\u0131kar\u0131r. Bitki abiyotik stresi, hastal\u0131k direnci, i\u015fleme ve di\u011fer y\u00f6nlerde yayg\u0131n olarak uygulanmaktad\u0131r. Bu \u00e7al\u0131\u015fma, palmiye a\u011fa\u00e7lar\u0131n\u0131n k\u00f6k, dal ve yapraklar\u0131ndaki u\u00e7ucu bile\u015fenleri tan\u0131mlamak ve analiz etmek, \u00e7e\u015fitlilik ve zenginle\u015fme \u00f6zelliklerini ara\u015ft\u0131rmak ve \u00fc\u00e7 b\u00f6l\u00fcm aras\u0131ndaki metabolitlerdeki \u00f6nemli farkl\u0131l\u0131klar\u0131 analiz etmek i\u00e7in kapsaml\u0131 hedefli metabolomik teknikleri kullanmay\u0131 ama\u00e7lamaktad\u0131r. Bu, gelecekte metabolik yollar\u0131n ve gen seviyelerinin derinlemesine analizi i\u00e7in temel olu\u015fturacak ve palmiye a\u011fac\u0131 kaynak kullan\u0131m b\u00f6l\u00fcmlerinin se\u00e7imi ve odunsu olmayan kaynaklar\u0131n geli\u015ftirilmesi ve kullan\u0131m\u0131 i\u00e7in veri deste\u011fi sa\u011flayacakt\u0131r.<\/p>\n

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\nBitkiler b\u00fcy\u00fcme s\u00fcre\u00e7leri s\u0131ras\u0131nda atmosferi temizleyebilen, havadaki bakteri i\u00e7eri\u011fini azaltabilen, insan v\u00fccuduna girdikten sonra zararl\u0131 maddeleri akci\u011ferlerden etkili bir \u015fekilde uzakla\u015ft\u0131rabilen, yorgunlu\u011fu ortadan kald\u0131rabilen, uykuyu iyile\u015ftirebilen, insan ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131n\u0131 art\u0131rabilen ve kanser ve hipertansiyon gibi kronik hastal\u0131klar\u0131n tedavisine yard\u0131mc\u0131 olabilen u\u00e7ucu bile\u015fikler salg\u0131lar. Bitkilerin farkl\u0131 k\u0131s\u0131mlar\u0131 u\u00e7ucu bile\u015fenler salabilir ve bitkilerin farkl\u0131 k\u0131s\u0131mlar\u0131ndaki u\u00e7ucu metabolitlerin incelenmesi, bitkilerin farkl\u0131 k\u0131s\u0131mlar\u0131n\u0131n geli\u015ftirilmesi ve kullan\u0131lmas\u0131 i\u00e7in yararl\u0131d\u0131r.<\/p>\n

Bu \u00e7al\u0131\u015fmada palmiye a\u011fa\u00e7lar\u0131n\u0131n k\u00f6k, dal ve yapraklar\u0131ndaki u\u00e7ucu metabolitler \u00fczerinde metabolomik analizi yap\u0131lm\u0131\u015f ve terpenler, esterler, heterosiklik bile\u015fikler ve hidrokarbonlar dahil olmak \u00fczere 16 kategoriye ayr\u0131lan 589 u\u00e7ucu metabolit tan\u0131mlanm\u0131\u015ft\u0131r. PCA sonu\u00e7lar\u0131ndan, farkl\u0131 k\u0131s\u0131mlar aras\u0131nda farkl\u0131l\u0131klar oldu\u011fu g\u00f6r\u00fclebilir; k\u00fcmeleme sonu\u00e7lar\u0131, \u00e7o\u011fu metabolitin dallarda ve yapraklarda nispeten y\u00fcksek seviyelere sahip oldu\u011funu g\u00f6stermektedir.<\/p>\n

K\u00f6kler ve dallar, k\u00f6kler ve yapraklar aras\u0131ndaki diferansiyel metabolitler terpenler, esterler, heterosiklik bile\u015fikler, hidrokarbonlar ve alkollerdir; bunlar aras\u0131nda terpenler, esterler, heterosiklik bile\u015fikler ve a\u015fa\u011f\u0131 reg\u00fcle edilen modlar ana olanlard\u0131r ve k\u00f6klerde \u00f6nemli \u00f6l\u00e7\u00fcde azalm\u0131\u015ft\u0131r; Hidrokarbonlar ve alkoller aras\u0131ndaki diferansiyel metabolitlerin yukar\u0131 reg\u00fclasyonu bask\u0131nd\u0131r ve bu iki madde t\u00fcr\u00fc k\u00f6klerde \u00f6nemli \u00f6l\u00e7\u00fcde yukar\u0131 do\u011fru birikir. Dallar ve yapraklar aras\u0131ndaki diferansiyel metabolitlere yukar\u0131 reg\u00fcle edilen modlar hakimdir ve terpenler ana yukar\u0131 reg\u00fcle edilen bile\u015fenlerdir.<\/p>\n

Terpenoidler do\u011fada yayg\u0131n olarak bulunan ve bitkilerin \u00f6nemli u\u00e7ucu bile\u015fikleridir. Anti-t\u00fcm\u00f6r, antibakteriyel, anti-inflamatuar, yat\u0131\u015ft\u0131r\u0131c\u0131 ve sakinle\u015ftirici etkilere sahiptirler ve esans, baharat, g\u00fcnl\u00fck kimyasal \u00fcr\u00fcnler vb. gibi bir\u00e7ok alanda yayg\u0131n olarak kullan\u0131lmaktad\u0131rlar. Bu \u00e7al\u0131\u015fmada palmiye a\u011fa\u00e7lar\u0131nda 162 terpenoid metabolit tespit edilmi\u015ftir. \u00c7o\u011fu terpenoidin birikimi k\u00f6klerde azalmakta ve yapraklarda daha y\u00fcksek seviyelerde olmak \u00fczere dallarda ve yapraklarda birikmektedir. Ancak limonen, \u03b2 - iyonon, \u03b1 - pinen, \u03b1 - terpineol, magnolol ve sedirol gibi terpenoidlerin birikimi artmaktad\u0131r. Monoterapi bile\u015fiklerinin \u00f6nemli temsilci bile\u015fenlerinden biri olan ve limon, portakal ve mandalina kabu\u011fu gibi bitkilerde yayg\u0131n olarak bulunan limonen gibi bu bile\u015fiklerin \u00e7o\u011funun \u00f6nemli farmakolojik aktivitelere ve fonksiyonel etkilere sahip oldu\u011fu kan\u0131tlanm\u0131\u015ft\u0131r. G\u00fc\u00e7l\u00fc geni\u015f spektrumlu antibakteriyel etkilere sahiptir ve g\u0131da kaynakl\u0131 patojenler, bitki patojeni mantarlar vb. \u00fczerinde iyi inhibit\u00f6r etkileri vard\u0131r; \u03b2 - iyonon \u00f6nemli bir baharatt\u0131r ve retinoik asit, retinol, \u03b2 - karoten ve A vitamini sentezi i\u00e7in \u00f6nc\u00fc bir bile\u015fiktir. Meme kanseri h\u00fccreleri, mide kanseri h\u00fccreleri, karaci\u011fer kanseri h\u00fccreleri, prostat kanseri h\u00fccreleri vb. \u00fczerinde g\u00fc\u00e7l\u00fc bir inhibit\u00f6r etkiye sahiptir; \u03b1 - Pinene ve \u03b1 - terpineol, terebentinin ana bile\u015fenleridir ve \u00e7e\u015fitli \u00f6nemli organik bile\u015fiklerin sentezlenmesi i\u00e7in ara \u00fcr\u00fcnlerdir. Antibakteriyel, anti-inflamatuar ve antikanser gibi \u00e7e\u015fitli aktivitelere sahiptirler.<\/p>\n

Diferansiyel metabolit metabolik yollar\u0131n\u0131n analizine g\u00f6re, diferansiyel metabolitler seskiterpenler ve triterpenlerin biyosentez yollar\u0131nda \u00f6nemli \u00f6l\u00e7\u00fcde zenginle\u015fmi\u015ftir. Trans - \u03b2 - farnesene, \u03b1 - farnesene, \u03b2 - selenene ve \u03b2 - myrrh dahil olmak \u00fczere dokuz diferansiyel metabolit bu sentetik yolda yer almaktad\u0131r. Seskiterpenler ve triterpenlerin biyosentetik yollar\u0131 terpenoid sentezi i\u00e7in \u00f6nemli yollardan biridir. Farkl\u0131 k\u0131s\u0131mlardaki terpenoid i\u00e7eri\u011findeki farkl\u0131l\u0131klar, terpenoid ile ilgili genlerin d\u00fczenlenmesi ve ilgili enzimlerin katalizi ile yak\u0131ndan ili\u015fkilidir. \u0130lgili d\u00fczenleyici genler \u00fczerinde daha derinlemesine ara\u015ft\u0131rmalara ihtiya\u00e7 vard\u0131r.<\/p>\n

\u00d6zetle, Anthurium palmatum'un dallar\u0131 ve yapraklar\u0131 u\u00e7ucu metabolitler bak\u0131m\u0131ndan zengindir ve bir\u00e7ok \u00f6nemli aktiviteye sahip terpenoidler yukar\u0131 do\u011fru d\u00fczenlenmi\u015ftir. Dallar ve yapraklar Anthurium palmatum'un geli\u015ftirilmesi ve kullan\u0131m\u0131 i\u00e7in \u00f6nemli par\u00e7alard\u0131r. U\u00e7ucu metabolitlere dayanarak, kokulu toz, t\u00fcts\u00fc, u\u00e7ucu ya\u011f vb. gibi bir dizi odun d\u0131\u015f\u0131 \u00fcr\u00fcne d\u00f6n\u00fc\u015ft\u00fcr\u00fclebilirler; Ayr\u0131ca, orman sa\u011fl\u0131\u011f\u0131 alan\u0131nda, palmiye a\u011fac\u0131 sa\u011fl\u0131\u011f\u0131 geli\u015ftirmek i\u00e7in bir a\u011fa\u00e7 t\u00fcr\u00fc olarak dikilebilir. Orman banyo alanlar\u0131nda, sa\u011fl\u0131k parkurlar\u0131nda, a\u00e7\u0131k hava e\u011flence yerlerinde ve di\u011fer ortamlarda u\u00e7ucu metabolitlerin sa\u011fl\u0131\u011fa faydalar\u0131nda rol oynayabilir.<\/p>","protected":false},"excerpt":{"rendered":"

Analysis of differences in volatile metabolites in different parts of palm trees based on extensive targeted metabolomics Ormosia henryi is an evergreen tree of the legume family, mainly distributed in subtropical regions of China, mainly in provinces such as Jiangxi, Zhejiang, Anhui, Hubei, Hunan, Guangdong, Sichuan, Guizhou, and Yunnan. Due to its low seed setting […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nAnalysis of differences in volatile metabolites in different parts of palm trees based on extensive targeted metabolomics - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/extensive-targeted-metabolomics\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Analysis of differences in volatile metabolites in different parts of palm trees based on extensive targeted metabolomics - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Analysis of differences in volatile metabolites in different parts of palm trees based on extensive targeted metabolomics Ormosia henryi is an evergreen tree of the legume family, mainly distributed in subtropical regions of China, mainly in provinces such as Jiangxi, Zhejiang, Anhui, Hubei, Hunan, Guangdong, Sichuan, Guizhou, and Yunnan. 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