{"id":3795,"date":"2024-08-03T08:01:58","date_gmt":"2024-08-03T08:01:58","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=3795"},"modified":"2024-08-03T08:01:58","modified_gmt":"2024-08-03T08:01:58","slug":"passion-fruit-peel","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/passion-fruit-peel\/","title":{"rendered":"\u00c7ark\u0131felek meyvesi kabu\u011funda tirozinaz inhibe edici aktiviteye sahip yeni bir lignan bile\u015fi\u011fi"},"content":{"rendered":"<p>\u00c7ark\u0131felek meyvesi kabu\u011funda tirozinaz inhibe edici aktiviteye sahip yeni bir lignan bile\u015fi\u011fi<br \/>\nPassiflora edulis Sims, Passifloraceae familyas\u0131na ait, \u00e7ark\u0131felek meyvesi, yumurta meyvesi, Brezilya meyvesi vb. olarak da bilinen otsu bir asma bitkisidir. 2018 y\u0131l\u0131nda, \u00c7in'deki \u00e7ark\u0131felek meyvesi ekim alan\u0131 60000 hektar\u0131 a\u015fm\u0131\u015ft\u0131r; bunlardan Guangxi yakla\u015f\u0131k 33350 hektarl\u0131k bir ekim alan\u0131na ve 300000 tonluk bir verime sahip olup, \u00fclke toplam\u0131n\u0131n 70%'sini olu\u015fturmaktad\u0131r ve \u00fcretim de\u011feri yakla\u015f\u0131k 2 milyar yuan'd\u0131r. \u00c7ark\u0131felek meyvesinin kabu\u011fu, taze meyvenin a\u011f\u0131rl\u0131\u011f\u0131n\u0131n yakla\u015f\u0131k 50% ila 55%'sini olu\u015fturur, ancak i\u015fleme s\u0131ras\u0131nda kabuk genellikle at\u0131l\u0131r, bu da sadece \u00e7evre i\u00e7in ciddi kirlili\u011fe neden olmakla kalmaz, ayn\u0131 zamanda b\u00fcy\u00fck bir kaynak israf\u0131na da neden olur. Bu nedenle, \u00e7ark\u0131felek meyvesi kabu\u011funun bile\u015fimi ve aktivitesinin incelenmesi, \u00e7ark\u0131felek meyvesinin kaynak kullan\u0131m\u0131 i\u00e7in temel veriler sa\u011flayabilir.<\/p>\n<p>\u00c7al\u0131\u015fmalar, \u00e7ark\u0131felek meyvesinin kabu\u011funun sadece polisakkaritler, flavonoidler ve antosiyaninler de\u011fil, ayn\u0131 zamanda alkaloidler, terpenler ve di\u011fer maddeleri de i\u00e7erdi\u011fini g\u00f6stermi\u015ftir. Peng ve arkada\u015flar\u0131 mor meyveli \u00e7ark\u0131felek meyvesinin kabu\u011fundan \u00fc\u00e7 antosiyanin izole etmi\u015ftir. Zhu ve arkada\u015flar\u0131 mor meyve \u00e7ark\u0131felek meyvesinin kabu\u011funda 5 antosiyanin tespit etmi\u015ftir. He ve arkada\u015flar\u0131 Fujian'\u0131n \"Purple Fragrant No.1\" mor meyve \u00e7ark\u0131felek meyvesinin kabu\u011funda 12 antosiyanin oldu\u011funu bildirmi\u015ftir. Buradan, \u00e7ark\u0131felek meyvesi kabu\u011funun bile\u015fimi \u00fczerine yap\u0131lan ara\u015ft\u0131rmalar\u0131n a\u011f\u0131rl\u0131kl\u0131 olarak antosiyaninlere odakland\u0131\u011f\u0131, lignanlar \u00fczerine ise nispeten az say\u0131da rapor oldu\u011fu g\u00f6r\u00fclebilir. Bu \u00e7al\u0131\u015fman\u0131n amac\u0131, \u00e7ark\u0131felek meyvesi kabu\u011funun antosiyaninler d\u0131\u015f\u0131ndaki biyoaktif bile\u015fenlerini daha fazla ara\u015ft\u0131rmak ve \u00e7ark\u0131felek meyvesi kabu\u011funun kullan\u0131m de\u011ferini art\u0131rmak i\u00e7in tirozinaz aktivite test kiti ve molek\u00fcler yerle\u015ftirme yoluyla aktivitelerini taramakt\u0131r.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-3796\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-9.png\" alt=\"\" width=\"958\" height=\"654\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-9.png 958w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-9-768x524.png 768w\" sizes=\"(max-width: 958px) 100vw, 958px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-3797\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-8.png\" alt=\"\" width=\"954\" height=\"128\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-8.png 954w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-8-768x103.png 768w\" sizes=\"(max-width: 954px) 100vw, 954px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-3798\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-1.jpg\" alt=\"\" width=\"782\" height=\"236\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-1.jpg 782w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-1-768x232.jpg 768w\" sizes=\"(max-width: 782px) 100vw, 782px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-3799\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4.jpg\" alt=\"\" width=\"782\" height=\"431\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4.jpg 782w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-768x423.jpg 768w\" sizes=\"(max-width: 782px) 100vw, 782px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-3800\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-7.png\" alt=\"\" width=\"458\" height=\"220\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-3801\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6.jpg\" alt=\"\" width=\"860\" height=\"282\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6.jpg 860w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-768x252.jpg 768w\" sizes=\"(max-width: 860px) 100vw, 860px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-3802\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-5.png\" alt=\"\" width=\"862\" height=\"618\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-5.png 862w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-5-768x551.png 768w\" sizes=\"(max-width: 862px) 100vw, 862px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-3803\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-4.png\" alt=\"\" width=\"850\" height=\"264\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-4.png 850w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-4-768x239.png 768w\" sizes=\"(max-width: 850px) 100vw, 850px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-3804\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-3.png\" alt=\"\" width=\"840\" height=\"582\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-3.png 840w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-3-768x532.png 768w\" sizes=\"(max-width: 840px) 100vw, 840px\" \/>Guangxi'deki \u00e7ark\u0131felek meyvesi verimi 2015 y\u0131l\u0131nda 68500 tondan 2019 y\u0131l\u0131nda 312800 tona y\u00fckselmi\u015ftir ve ekim alan\u0131 2015 y\u0131l\u0131ndan bu yana y\u0131ll\u0131k ortalama 35,6% oran\u0131nda artarak 2019 y\u0131l\u0131nda 28280 hektara ula\u015fm\u0131\u015ft\u0131r. Meyve suyu \u00fcretimi s\u0131ras\u0131nda, \u00e7ark\u0131felek meyvesinden elde edilen 75%'den fazla at\u0131k tam olarak kullan\u0131lmamaktad\u0131r. \u00c7ark\u0131felek meyvesi kabu\u011fundan elde edilen biyoaktif bile\u015fiklerin ila\u00e7, kozmetik ve g\u0131da end\u00fcstrilerinde kullan\u0131lmak \u00fczere nas\u0131l geri d\u00f6n\u00fc\u015ft\u00fcr\u00fclece\u011fi, derinlemesine ara\u015ft\u0131rmaya de\u011fer bir sorundur.<br \/>\n\u00c7ark\u0131felek meyvesinin kabu\u011funun safla\u015ft\u0131r\u0131lmas\u0131 ve izole edilmesiyle, sophocarpin ve syringin olmak \u00fczere iki basit fenilpropanoid ve yeni bir lignan olan inositol lignan olmak \u00fczere \u00fc\u00e7 bile\u015fik elde edilmi\u015ftir. \u00c7am kabu\u011fu glikozidi, mantar b\u00fcy\u00fcmesini ve kararma reaksiyonlar\u0131n\u0131 engelleyebilen bir t\u00fcr \u00e7am kabu\u011fu alkol\u00fc glikozididir. Liu ve arkada\u015flar\u0131 siringinin ovariektomize fareler \u00fczerinde g\u00fc\u00e7l\u00fc bir anti osteoporoz etkisi oldu\u011funu ve molek\u00fcler mekanizmas\u0131n\u0131n NF - \u03ba B ve PI3K\/Akt sinyal yolaklar\u0131 ile ili\u015fkili olabilece\u011fini bulmu\u015flard\u0131r. Li ve arkada\u015flar\u0131, siringinin AMPK \u03b1 ve otofaji ile ilgili sinyal yollar\u0131n\u0131 aktive ederek H9c2 kardiyomiyositlerinin anjiyotensin II ile ind\u00fcklenen hipertrofisini hafifletti\u011fini bulmu\u015flard\u0131r. Buna dayanarak, inositol lignanlar \u00fczerinde anti-enflamatuar ve anti-t\u00fcm\u00f6r aktivite testleri ger\u00e7ekle\u015ftirdik, ancak iyi bir aktivite g\u00f6steremedik (veriler yay\u0131nlanmad\u0131). \u00dc\u00e7 bile\u015fi\u011fin tirozinaz inhibit\u00f6r aktivitesini tespit ederek, bile\u015fik 1'in tirozinaz inhibit\u00f6r aktivitesine sahip oldu\u011fu bulundu. Ancak tirozinaz inhibit\u00f6r aktivitesi i\u00e7in \u00fc\u00e7 bile\u015fi\u011fin taranmas\u0131ndan sonra, inositol lignan\u0131n tirozinaz inhibit\u00f6r aktivitesine sahip oldu\u011fu bulunmu\u015ftur. Ayn\u0131 zamanda, tirozinaz proteinleri \u00fczerinde yap\u0131lan molek\u00fcler kenetlenme \u00e7al\u0131\u015fmalar\u0131, inositol ligninin tirozinaz ile en d\u00fc\u015f\u00fck ba\u011flanma enerjisine sahip oldu\u011funu ve ikisi aras\u0131nda g\u00fc\u00e7l\u00fc bir ba\u011flanma etkisi oldu\u011funu g\u00f6stermi\u015ftir. Molek\u00fcler dinamik sim\u00fclasyonlar\u0131, ba\u011flanma derecelerini ve kararl\u0131l\u0131klar\u0131n\u0131 daha da do\u011frulam\u0131\u015ft\u0131r. \u00d6zetle, bu \u00e7al\u0131\u015fma mor meyveli \u00e7ark\u0131felek meyvesinin kabu\u011funun biyoaktif bile\u015fenlerini ara\u015ft\u0131rm\u0131\u015ft\u0131r; bu da kabu\u011fun kullan\u0131m de\u011ferini art\u0131rmak ve \u00e7ark\u0131felek meyvesinin ekonomik katma de\u011ferini daha da geni\u015fletmek i\u00e7in faydal\u0131d\u0131r.<\/p>","protected":false},"excerpt":{"rendered":"<p>A novel lignan compound with tyrosinase inhibitory activity in the peel of passion fruit Passiflora edulis Sims is a herbaceous vine plant belonging to the Passifloraceae family, also known as passion fruit, egg fruit, Brazilian fruit, etc. In 2018, the planting area of passion fruit in China exceeded 60000 hectares, of which Guangxi had a [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - 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