{"id":3434,"date":"2024-06-27T01:15:30","date_gmt":"2024-06-27T01:15:30","guid":{"rendered":"https:\/\/pharm.sinocurechem.com\/?p=3434"},"modified":"2024-06-27T01:15:30","modified_gmt":"2024-06-27T01:15:30","slug":"benzylacetone-properties-applications-and-production-methods","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/benzi\u0307lasetonun-ozelli\u0307kleri\u0307-uygulamalari-ve-ureti\u0307m-yontemleri\u0307\/","title":{"rendered":"Benzilaseton: \u00d6zellikler, Uygulamalar ve \u00dcretim Y\u00f6ntemleri"},"content":{"rendered":"

Benzilaseton: \u00d6zellikler, Uygulamalar ve \u00dcretim Y\u00f6ntemleri<\/span><\/b><\/b><\/p>\n

Benzilaseton<\/span><\/b>\u00a0<\/span><\/b>2550-26-7<\/span><\/b><\/b><\/p>\n

Benzilaseton (IUPAC ad\u0131: 4-phenylbutan-2-one) tatl\u0131 \u00e7i\u00e7ek kokulu bir s\u0131v\u0131d\u0131r ve \u00e7i\u00e7eklerde (\u00f6rne\u011fin, \u00e7akal t\u00fct\u00fcn\u00fc, Nicotiana attenuata) en bol bulunan cezbedici bile\u015fik ve kakaonun u\u00e7ucu bile\u015fenlerinden biri olarak kabul edilir. Kavun sinekleri (Bactrocera cucurbitae) i\u00e7in yem olarak ve parf\u00fcm ve sabunlarda koku verici olarak kullan\u0131l\u0131r<\/span>.<\/span><\/p>\n

Benzil Asetonun Kimyasal \u00d6zellikleri<\/span><\/b><\/b><\/p>\n

G\u00f6r\u00fcn\u00fc\u015f: renksiz s\u0131v\u0131. Tatl\u0131 \u00e7i\u00e7ek kokusu.<\/span><\/p>\n

Suda \u00e7\u00f6z\u00fcn\u00fcrl\u00fck: hafif<\/span><\/b><\/p>\n

Erime noktas\u0131: -13\u00b0C<\/span><\/p>\n

Kaynama Noktas\u0131: 235 \u00b0C (lit.)<\/span><\/p>\n

Yo\u011funluk: 25 \u00b0C'de 0,989 g\/mL (lit.)<\/span><\/p>\n

Buhar bas\u0131nc\u0131: 0,0386 hPa (20 \u00b0C)<\/span><\/p>\n

K\u0131r\u0131lma indisi: n20\/D 1.512 (lit.)<\/span><\/p>\n

Parlama Noktas\u0131: 209 \u00b0F<\/span><\/p>\n

Saklama ko\u015fulu: Kuru, Oda S\u0131cakl\u0131\u011f\u0131nda M\u00fch\u00fcrl\u00fc<\/span><\/p>\n

\u00c7\u00f6z\u00fcn\u00fcrl\u00fck:Kloroform, Metanol<\/span><\/p>\n

Form:S\u0131v\u0131<\/span><\/p>\n

Renk:Berrak renksiz ila soluk sar\u0131<\/span><\/p>\n

Koku: 100.00'de %. \u00e7i\u00e7eksi balsam<\/span><\/p>\n

Koku:\u00c7i\u00e7eksi<\/span><\/p>\n

Suda \u00e7\u00f6z\u00fcn\u00fcrl\u00fck:PRACTICALLY INSOLUBLE<\/span><\/p>\n

BRN:1907123<\/span><\/p>\n

25\u00b0C'de LogP:2<\/span><\/p>\n

Kimyasal \u00d6zellikler <\/span><\/b><\/b><\/p>\n

Renksiz s\u0131v\u0131. Kaynama noktas\u0131 235\u2103, 115\u2103 (1.73kPa), ba\u011f\u0131l yo\u011funluk 0.985 (22\/4\u2103), k\u0131r\u0131lma indisi 1.511 (22\u2103), parlama noktas\u0131 98\u2103.<\/span><\/p>\n

Birincil Aroma: \u00c7i\u00e7eksi; \u0130kincil Aroma: Ye\u015fil.<\/span><\/p>\n

Koku Tan\u0131m\u0131: Genellikle sabun yap\u0131m\u0131nda kullan\u0131lan benzilaseton, kakao ve ahudududa do\u011fal olarak bulunan \u00e7i\u00e7eksi ve tatl\u0131 bir aromaya sahiptir.<\/span><\/p>\n

Do\u011fal Kaynaklar: S\u0131\u011f\u0131r eti, Kakao, Yumurta, B\u00f6\u011f\u00fcrtlen, Su Yam.<\/span><\/p>\n

Depolama Y\u00f6ntemleri<\/span><\/b><\/b><\/p>\n

Kab\u0131 s\u0131k\u0131ca kapal\u0131 tutun, s\u0131k\u0131ca paketlenmi\u015f da\u011f\u0131t\u0131c\u0131ya yerle\u015ftirin ve serin, kuru bir yerde saklay\u0131n.<\/span><\/p>\n

Kullan\u0131m Alanlar\u0131 <\/span><\/b><\/b><\/p>\n

Benzil Aseton esas olarak aroma ve kokular\u0131n ve farmas\u00f6tik ara \u00fcr\u00fcnlerin form\u00fclasyonunda kullan\u0131l\u0131r. Benzil Asetonun geleneksel \u00fcretim y\u00f6ntemleri a\u015fa\u011f\u0131daki gibidir: (1) Benzil klor\u00fcr yo\u011funla\u015ft\u0131rma, hidroliz ve dekarbonasyon ile elde edilir; (2) Benzil Aseton, Benzaldehit ve Asetondan sentezlenir ve daha sonra hidrojenasyon indirgemesi ile Benzil Aseton elde edilir. Geleneksel benzil aseton \u00fcretim y\u00f6nteminin bir\u00e7ok ad\u0131m\u0131, karma\u015f\u0131k s\u00fcreci, b\u00fcy\u00fck ekipman\u0131 ve sermaye yat\u0131r\u0131m\u0131 vard\u0131r ve \u00fcretim s\u00fcreci, ba\u015fa \u00e7\u0131k\u0131lmas\u0131 zor olan ve i\u015fletmeye b\u00fcy\u00fck bir \u00e7evre koruma bask\u0131s\u0131 getiren b\u00fcy\u00fck miktarda at\u0131k tuzlu su \u00fcretir.<\/span><\/p>\n

Benzilaseton (Benzylacetone), t\u00fcts\u00fc ya\u011f\u0131 ve ekstraktlar\u0131n\u0131n en s\u0131k bildirilen bile\u015fenlerinden biridir. T\u00fcts\u00fc ya\u011f\u0131nda daha az miktarda ba\u015fka fenolikler de vard\u0131r, ancak bu ana fenoliklerden biridir. \u0130lgin\u00e7 bir \u015fekilde, The Good Scents Company'ye g\u00f6re, bu bile\u015fik balzamik aromas\u0131na ra\u011fmen \u00e7ilek aromas\u0131na sahiptir. T\u00fcts\u00fc ya\u011f\u0131nda 0.5% ila 8% aras\u0131nda de\u011fi\u015fti\u011fi g\u00f6zlemlenmi\u015f ve rapor edilmi\u015ftir ve karakteristik aroma belirleyici bile\u015fiklerinden biri olarak bildirilmi\u015ftir.<\/span><\/p>\n

Benzilasetonun, t\u00fcts\u00fcde bir dizi 2-feniletilkromon \u00fcretimine yol a\u00e7an \u00e7ok \u00f6nemli bir ba\u015fka metabolik s\u00fcrecin \"yan \u00fcr\u00fcn\u00fc\" oldu\u011fundan \u015f\u00fcphelenilmektedir. Bu daha a\u011f\u0131r fenolik bile\u015fiklerin b\u00fcy\u00fck \u00e7o\u011funlu\u011fu u\u00e7ucu ya\u011fa u\u00e7maz, ancak kromatogram\u0131n en sonunda genellikle az miktarda megapanax kromon (Flindersiachromone) bulunur. Bu kromon grubu t\u00fcts\u00fcye \u00e7ok \u00f6zg\u00fcd\u00fcr ve baz\u0131 ilgin\u00e7 biyolojik \u00f6zellikleri nedeniyle y\u0131llar boyunca ara\u015ft\u0131rmalar\u0131n b\u00fcy\u00fck ilgisini \u00e7ekmi\u015ftir.<\/span><\/p>\n

Benzilaseton \u0131s\u0131t\u0131lm\u0131\u015f sedum a\u011fac\u0131ndan sal\u0131n\u0131r ve solundu\u011funda farelerde lokomotor aktiviteyi azaltmada etkilidir.<\/span><\/p>\n

Bu \u00e7al\u0131\u015fmada, benzilaseton ve t\u00fcrevleri aras\u0131ndaki ili\u015fki, farelerdeki sedatif aktiviteleri ve bu bile\u015fiklerin kimyasal yap\u0131lar\u0131 kar\u015f\u0131la\u015ft\u0131r\u0131larak ara\u015ft\u0131r\u0131lm\u0131\u015ft\u0131r.<\/span><\/p>\n

Sonu\u00e7lar, benzilasetonlar\u0131n, g\u00fcc\u00fc karbon zincirindeki fonksiyonel gruplara, benzen halkas\u0131ndaki s\u00fcbstit\u00fcentlere ve bunlar\u0131n kombinasyonlar\u0131na ba\u011fl\u0131 olarak de\u011fi\u015fen yat\u0131\u015ft\u0131r\u0131c\u0131 aktiviteye sahip oldu\u011funu g\u00f6stermektedir.<\/span><\/p>\n

Ara\u015ft\u0131rmac\u0131lar, yat\u0131\u015ft\u0131r\u0131c\u0131 aktivite i\u00e7in \u00f6nemli olan yap\u0131sal \u00f6zellikleri belirlemek i\u00e7in bir dizi 17 benzilaseton t\u00fcrevi kullanarak kantitatif bir yap\u0131-aktivite ili\u015fkisi \u00e7al\u0131\u015fmas\u0131 y\u00fcr\u00fctt\u00fcler.<\/span><\/p>\n

Kullan\u0131m <\/span><\/b><\/b><\/p>\n

Farmas\u00f6tik sentez i\u00e7in ara \u00fcr\u00fcn olarak kullan\u0131l\u0131r<\/span><\/p>\n

Uygulama alanlar\u0131<\/span><\/b><\/b><\/p>\n

1.\u00a0<\/span>Kakaoda u\u00e7ucu bile\u015fen olarak bulunur.Sabun aromalar\u0131n\u0131n haz\u0131rlanmas\u0131nda kullan\u0131l\u0131r.Sabun aromalar\u0131n\u0131n haz\u0131rlanmas\u0131nda kullan\u0131l\u0131r. Kavun sinekleri i\u00e7in cezbedici olarak kullan\u0131l\u0131r. 4-oksosiklohekzankarboksaldehit t\u00fcrevlerinin haz\u0131rlanmas\u0131nda kimyasal sentezde kullan\u0131l\u0131r.<\/span><\/p>\n

2.\u00a0<\/span>Lezzet End\u00fcstrisi<\/span>:<\/span>Asetofenon parf\u00fcmlerde, aromalarda ve kokularda yayg\u0131n olarak kullan\u0131lan \u00f6nemli bir koku bile\u015fenidir. \u00dcr\u00fcnlere uzun s\u00fcre kal\u0131c\u0131 bir koku verebilir ve \u00fcr\u00fcnlerin katmanla\u015fmas\u0131n\u0131 ve \u00e7ekicili\u011fini art\u0131rabilir.<\/span><\/p>\n

3.\u00a0<\/span>Kozmetik End\u00fcstrisi<\/span>:<\/span>Kozmetikte, asetofenon genellikle kokularda ve tatland\u0131r\u0131c\u0131larda bir bile\u015fen olarak da kullan\u0131l\u0131r. Kozmetiklere ho\u015f bir koku verir ve \u00fcr\u00fcn kalitesini ve pazar rekabet\u00e7ili\u011fini art\u0131r\u0131r.<\/span><\/p>\n

4.\u00a0<\/span>Eczac\u0131l\u0131k alan\u0131<\/span>:<\/span>Asetofenon ve t\u00fcrevleri farmas\u00f6tik alanda da kullan\u0131lmaktad\u0131r. Farmas\u00f6tik hammaddeler ve farmas\u00f6tik ara \u00fcr\u00fcnler gibi \u00e7ok \u00e7e\u015fitli ila\u00e7lar\u0131n ve biyolojik olarak aktif bile\u015fiklerin haz\u0131rlanmas\u0131 i\u00e7in organik sentezde bir ara \u00fcr\u00fcn olarak kullan\u0131l\u0131r.<\/span><\/p>\n

5.\u00a0<\/span>Organik sentez<\/span>:<\/span>Asetofenon organik sentez alan\u0131nda \u00f6nemli bir konuma sahiptir ve bir\u00e7ok organik bile\u015fik i\u00e7in \u00f6nemli bir sentez ara maddesidir. Asetofenonun oksidasyonu, indirgenmesi, hidroksilasyonu ve di\u011fer reaksiyonlar\u0131 yoluyla ketonlar, alkoller ve eterler gibi \u00e7e\u015fitli organik bile\u015fikler haz\u0131rlanabilir.<\/span><\/p>\n

Haz\u0131rl\u0131k<\/span><\/b><\/b><\/p>\n

Y\u00f6ntem 1: Benzil asetonun sentez y\u00f6ntemi a\u015fa\u011f\u0131daki ad\u0131mlar\u0131 i\u00e7erir:<\/span><\/p>\n

(1) Kar\u0131\u015ft\u0131r\u0131c\u0131, refl\u00fc kondansat\u00f6r\u00fc ve termometre ile donat\u0131lm\u0131\u015f d\u00f6rt boyunlu bir balona al\u00fcminyum triklor\u00fcr (150 g, 1,1 mol), benzenin ilk k\u0131sm\u0131 (350 g) eklenir ve 30-35 \u00b0C s\u0131cakl\u0131kta iyice kar\u0131\u015ft\u0131r\u0131l\u0131r;<\/span><\/p>\n

(2) Ad\u0131m (1)'deki damlatma hunisine b\u00fctenon (73 g, 1 mol) ve benzenin ikinci k\u0131sm\u0131 (150 g) kar\u0131\u015f\u0131m\u0131 eklenmi\u015f, reaksiyon s\u0131cakl\u0131\u011f\u0131 30-35 \u00b0 C'de kontrol edilmi\u015ftir. 2,5-3 saat sonra benzen ve b\u00fctenon kar\u0131\u015f\u0131m\u0131n\u0131n ikinci k\u0131sm\u0131 damla damla eklenmi\u015f, reaksiyon 0.5 saat s\u00fcrd\u00fcr\u00fclm\u00fc\u015ft\u00fcr.5 saat, y\u0131kamak i\u00e7in su ilave edildi ve benzenin geri kazan\u0131lmas\u0131ndan sonra, ya\u011f banyosu rafinasyonu ger\u00e7ekle\u015ftirildi ve 80-85 \u00b0 C s\u0131cakl\u0131kta (50pa) 99.95 g elde etmek i\u00e7in topland\u0131; 98.97% benzil aseton i\u00e7eri\u011finin GC tespiti, verim 66.84%.<\/span><\/p>\n

Y\u00f6ntem 2: Kar\u0131\u015ft\u0131r\u0131c\u0131, refl\u00fc kondansat\u00f6r\u00fc, damlatma hunisi, termometre ile donat\u0131lm\u0131\u015f reaksiyon kab\u0131nda, 320 ml 60% siklohekzan k\u00fctle fraksiyonu ekleyin, gruplar halinde 1.3 mol stann\u00f6z klor\u00fcr ekleyin, etil asetoasetat (1) 2.3 mol ekleyin, 130 rpm kar\u0131\u015ft\u0131rma h\u0131z\u0131n\u0131 kontrol edin, reaksiyon 60 dakika, \u00e7\u00f6zeltinin s\u0131cakl\u0131\u011f\u0131n\u0131 65 \u00b0 C'ye y\u00fckseltin, 3 saat refl\u00fc yap\u0131n, benzil amin (3) 2.6 mol damla damla ekleyin. ) 2.6 mol, 3 saatte zaman kontrol\u00fcn\u00fcn damla damla eklenmesi, geri ak\u0131\u015f reaksiyonu 3 saat, ara \u00fcr\u00fcnlerin olu\u015fumu (4), \u00e7\u00f6zelti s\u0131cakl\u0131\u011f\u0131n\u0131 10 \u00b0 C'ye d\u00fc\u015f\u00fcr\u00fcn, 30% potasyum bis\u00fclfit \u00e7\u00f6zeltisinin 330 ml k\u00fctle fraksiyonunu ekleyin, 4 saat boyunca geri ak\u0131\u015fa devam edin, ya\u011fl\u0131 olu\u015fum, \u00e7\u00f6zelti pH'\u0131n\u0131 4'e ayarlamak i\u00e7in 20% oksalik asit k\u00fctle fraksiyonu ekleyin, 4 saat boyunca geri ak\u0131\u015fa devam edin, 1.13kPa dekompresyon distilasyonu, 95- 105 \u2103 fraksiyonun toplanmas\u0131, sodyum nitrat \u00e7\u00f6zeltisi y\u0131kama, 70% asetonitril y\u0131kama k\u00fctle fraksiyonu, yeniden kristalle\u015ftirmede 90% nitrometan k\u00fctle fraksiyonunda, kristal benzil aseton 241.68g, verim 71% elde edin.<\/span><\/p>\n

\u00dcretim y\u00f6ntemi <\/span><\/b><\/b><\/p>\n

Asetofenonun ana \u00fcretim y\u00f6ntemleri aras\u0131nda aromatik hidrokarbonlar\u0131n ketonlarla eterifikasyonu, asilasyon indirgemesi ve alkol-asit esterifikasyonu bulunmaktad\u0131r. Bunlar aras\u0131nda, aromatik hidrokarbonlar\u0131n ketonlarla eterifikasyon reaksiyonu en yayg\u0131n kullan\u0131lan end\u00fcstriyel \u00fcretim y\u00f6ntemlerinden biridir. Reaksiyon genellikle alkali ko\u015fullar alt\u0131nda ger\u00e7ekle\u015ftirilir ve asetofenon, asetofenon \u00f6nc\u00fcllerinin se\u00e7ici oksidasyonu, indirgenmesi veya hidroksilasyonu ile haz\u0131rlanabilir.<\/span><\/p>\n

(1)\u00a0<\/span>Benzil klor\u00fcrden yo\u011funla\u015ft\u0131rma, hidroliz ve dekarbonasyon ile elde edilir. (2) Benzilaseton, benzaldehit ve asetondan sentezlenir ve daha sonra hidrojenasyon ve indirgeme ile 4-fenilb\u00fctanon-2 elde edilir. 4-fenilb\u00fctanon-2, reaksiyon \u015fi\u015fesine etanol (95% 1100 ml), benzilaseton (480 g), Raney Ni (48 g) ve asetik asit konularak ve daha sonra s\u0131cakl\u0131k 48-50\u00b0C'de kontrol edilerek, kar\u0131\u015ft\u0131r\u0131larak ve miktar yeterli olana kadar atmosferik bas\u0131n\u00e7ta hidrojen emilerek haz\u0131rlan\u0131r. Reaksiyon 4-5 saat. Raney Ni s\u00fcz\u00fcld\u00fc. s\u00fcz\u00fcnt\u00fc buharla\u015ft\u0131r\u0131lm\u0131\u015f etanol, indirgenmi\u015f bas\u0131n\u00e7 alt\u0131nda dam\u0131tma, 123-125 \u2103 (2.67kPa) fraksiyonunun toplanmas\u0131, 465.8g i\u00e7in 4-fenilb\u00fctanon-2 elde edildi. k\u0131r\u0131lma indisi 1.513, verim 95.7%.<\/span><\/p>\n

Sentez y\u00f6ntemi<\/span><\/b><\/b><\/p>\n

Asetofenon, benziliden asetonun (benzaldehit ve asetondan haz\u0131rlan\u0131r) se\u00e7ici hidrojenasyonu ile haz\u0131rlanabilir.<\/span><\/b><\/p>\n

Benzil klor\u00fcrden yo\u011funla\u015ft\u0131rma, hidroliz ve dekarbonasyon yoluyla elde edilmi\u015ftir. Benziliden aseton, benzaldehit ve asetondan sentezlendi ve daha sonra hidrojenasyon ve indirgeme ile 4-fenilb\u00fctanon-2 elde edildi. 4-fenilb\u00fctanon-2, reaksiyon \u015fi\u015fesine etanol (95% 1100 ml), benziliden aseton (480 g), Raney Ni (48 g) ve asetik asit konularak ve ard\u0131ndan s\u0131cakl\u0131k 48-50 \u00b0C'de kontrol edilerek, kar\u0131\u015ft\u0131r\u0131larak ve miktar yeterli olana kadar atmosferik bas\u0131n\u00e7ta hidrojen emilerek haz\u0131rlanm\u0131\u015ft\u0131r. Reaksiyon 4-5 saat. filtrelenmi\u015f Raney Ni. filtrat buharla\u015ft\u0131r\u0131lm\u0131\u015f etanol, azalt\u0131lm\u0131\u015f bas\u0131n\u00e7 alt\u0131nda dam\u0131tma, 123-125 \u2103 (2.67kPa) fraksiyonu toplamak, 465.8g i\u00e7in 4-fenilb\u00fctanon-2 elde etmek. k\u0131r\u0131lma indisi 1.513, verim 95.7%.<\/span><\/p>\n

(2) Haz\u0131rlama y\u00f6ntemi:<\/span><\/p>\n

Fenilaseton haz\u0131rlama y\u00f6ntemine at\u0131fta bulunarak, reaksiyon i\u00e7in 100g (0.66mol) fenilpropanoik asit, 160g (2.66mol) buzlu asetik asit kullan\u0131lm\u0131\u015f, eterle ekstrakte edilmi\u015f ve ard\u0131ndan dam\u0131t\u0131lm\u0131\u015f ve fraksiyonlar 230 ila 235\u00b0C aras\u0131nda toplanarak 71% verimle 70g olarak 4-fenil-2-butanon elde edilmi\u015ftir. Saf 4-fenil-2-b\u00fctanon bp234\u00b0C.<\/span><\/p>\n

\u0130lk Yard\u0131m<\/span><\/b><\/b><\/p>\n

Haz\u0131ms\u0131zl\u0131k: T\u0131bbi yard\u0131m al\u0131n. A\u011fz\u0131n\u0131z\u0131 su ile \u00e7alkalay\u0131n.<\/span><\/p>\n

SOLUNUM: Derhal temiz havaya \u00e7\u0131kar\u0131n.<\/span><\/p>\n

Cilt: Cildi bol sabun ve suyla en az 15 dakika y\u0131kay\u0131n ve kirlenmi\u015f giysi ve ayakkab\u0131lar\u0131 \u00e7\u0131kar\u0131n.<\/span><\/p>\n

G\u00d6ZLER: G\u00f6zleri en az 15 dakika boyunca bol su ile y\u0131kay\u0131n, ara s\u0131ra \u00fcst ve alt g\u00f6z kapaklar\u0131n\u0131 kald\u0131r\u0131n. T\u0131bbi yard\u0131m al\u0131n.<\/span><\/p>\n

Ta\u015f\u0131ma ve Depolama<\/span><\/b><\/b><\/p>\n

DEPOLAMA: Serin ve kuru bir yerde saklay\u0131n. Hava ge\u00e7irmez kapta saklay\u0131n.<\/span><\/p>\n

ELLE\u00c7LEME: Toz, buhar, sis veya gazlar\u0131 solumaktan ka\u00e7\u0131n\u0131n. Cilt ve g\u00f6z ile temas\u0131ndan ka\u00e7\u0131n\u0131n.<\/span><\/p>\n

Tehlike Tan\u0131mlama<\/span><\/b><\/b><\/p>\n

S\u0130ND\u0130R\u0130M: Yutulmas\u0131 halinde zararl\u0131 olabilir.<\/span><\/p>\n

SOLUNUM: Solunum yollar\u0131n\u0131 tahri\u015f edebilir. Solunmas\u0131 halinde zararl\u0131 olabilir.<\/span><\/p>\n

C\u0130LT: Ciddi cilt tahri\u015fine neden olur. Deri yoluyla emilirse zararl\u0131 olabilir.<\/span><\/p>\n

G\u00f6zler: G\u00f6zleri tahri\u015f edebilir.<\/span><\/p>\n

AK Risk S\u00f6zc\u00fckleri: R 36\/38<\/span><\/p>\n

AB G\u00fcvenlik \u0130baresi: S 26 36<\/span><\/p>\n

Maruziyet kontrol\u00fc\/ki\u015fisel korunma<\/span><\/b><\/b><\/p>\n

K\u0130\u015e\u0130SEL KORUNMA: C\u0130LT: Cilt temas\u0131n\u0131 \u00f6nlemek i\u00e7in uygun koruyucu eldiven giyin. Giysi: Kimyasal \u00f6nl\u00fck giyin.<\/span><\/p>\n

RESP\u0130RAT\u00d6RLER: OSHA Respirat\u00f6r Y\u00f6netmeli\u011fi 29CFR 1910.134 veya Avrupa Standard\u0131 EN 149'a uyun. Gerekti\u011finde daima NIOSH veya Avrupa Standard\u0131 EN 149 onayl\u0131 solunum maskeleri kullan\u0131n.<\/span><\/p>\n

Yang\u0131n S\u00f6nd\u00fcrme \u00d6nlemleri<\/span><\/b><\/b><\/p>\n

Tutu\u015fma noktas\u0131: >100<\/span><\/p>\n

YANGINLA M\u00dcCADELE: Bas\u0131n\u00e7 gerektiren ba\u011f\u0131ms\u0131z solunum cihaz\u0131 (SCBA), MSHA\/NIOSH (onayl\u0131 veya e\u015fde\u011feri) ve tam koruyucu ekipman kullan\u0131n. Yang\u0131n\u0131 su spreyi, kuru kimyasal, karbondioksit veya kimyasal k\u00f6p\u00fck ile s\u00f6nd\u00fcr\u00fcn.<\/span><\/p>\n

Kaza Sonucu A\u00e7\u0131\u011fa \u00c7\u0131kma \u00d6nlemleri<\/span><\/b><\/b><\/p>\n

K\u00fc\u00e7\u00fck d\u00f6k\u00fclmeler\/s\u0131z\u0131nt\u0131lar: d\u00f6k\u00fcnt\u00fcy\u00fc inert malzeme (\u00f6rn. kuru kum veya toprak) ile emdirin ve kimyasal at\u0131k konteynerine koyun.<\/span><\/p>\n

G\u00fcvenlik Bilgileri<\/span><\/b><\/b><\/p>\n

Tehlike sembol\u00fc: Xi<\/span><\/p>\n

Tehlike S\u0131n\u0131f\u0131 Kodu: 38<\/span><\/p>\n

G\u00fcvenlik talimatlar\u0131: 37-24\/25<\/span><\/p>\n

WGK Almanya: 1<\/span><\/p>\n

RTECS numaras\u0131: EL9600000<\/span><\/p>\n

TSCA: Evet<\/span><\/p>\n

G\u00fcmr\u00fck kodu: 29143900<\/span><\/p>\n

Toksisite: Tav\u015fan'da a\u011f\u0131zdan LD50: 3200 mg\/kg<\/span><\/p>\n

G\u00fcvenlik Verileri<\/span><\/b><\/b><\/p>\n

Asetofenon cilt tahri\u015fine, ciddi g\u00f6z tahri\u015fine ve GHS s\u0131n\u0131fland\u0131rmas\u0131na g\u00f6re yutulmas\u0131 halinde tehlikelere neden olabilir. Koruyucu g\u00f6zl\u00fck ve eldiven giymek gibi uygun \u00f6nlemler al\u0131nmal\u0131d\u0131r.<\/span><\/p>\n

\u00c7evresel Etkiler<\/span><\/b><\/b><\/p>\n

Ayr\u0131\u015fana kadar \u0131s\u0131t\u0131ld\u0131\u011f\u0131nda tahri\u015f edici dumanlar ve gazlar a\u00e7\u0131\u011fa \u00e7\u0131karabilir.<\/span><\/p>\n

T\u0131bbi \u00c7al\u0131\u015fmalar<\/span><\/b><\/b><\/p>\n

Asetofenon, mantar tirozinaz\u0131n\u0131n potansiyel inhibisyonunu g\u00f6sterir ve i\u015ftah art\u0131rma ve egzersiz azaltma uygulamalar\u0131na sahip olabilir.<\/span><\/p>\n

G\u00fcvenlik ve \u00e7evresel etkiler<\/span><\/b><\/b><\/p>\n

Asetofenon normal kullan\u0131m ko\u015fullar\u0131 alt\u0131nda insanlar i\u00e7in nispeten g\u00fcvenlidir, ancak uzun s\u00fcreli maruz kalman\u0131n sa\u011fl\u0131k \u00fczerinde olumsuz etkileri olabilir. \u00dcretim ve kullan\u0131m s\u0131ras\u0131nda cilt temas\u0131n\u0131 ve gaz\u0131n solunmas\u0131n\u0131 \u00f6nlemek i\u00e7in uygun koruyucu \u00f6nlemler al\u0131nmal\u0131d\u0131r. Ayr\u0131ca, \u00e7evre \u00fczerindeki etkiyi en aza indirmek i\u00e7in asetofenon \u00fcretimi ve kullan\u0131m\u0131 s\u0131k\u0131 bir \u015fekilde kontrol edilmelidir.<\/span><\/p>\n

Tepkiler<\/span><\/b><\/b><\/p>\n

\u00c7o\u011fu metil keton bile\u015fi\u011fi gibi, benzilidenaseton da alfa konumunda hafif asidik bir bile\u015fiktir ve kar\u015f\u0131l\u0131k gelen enol bile\u015fi\u011fini vermek i\u00e7in \u00e7ok kolay bir \u015fekilde deprotonlanabilir. Bile\u015fik, a\u015fa\u011f\u0131daki fonksiyonel gruplar\u0131n varl\u0131\u011f\u0131 nedeniyle a\u015fa\u011f\u0131daki reaksiyonlara girebilir, \u00f6rne\u011fin: \u00e7ift ba\u011flar\u0131n bromine eklenmesi; dihidropiran bile\u015fikleri vermek i\u00e7in heterodien bile\u015fiklerinin olefinlerle Diels-Alder reaksiyonu; metil gruplar\u0131, dibenziliden aseton vermek i\u00e7in benzaldehit ile daha da yo\u011funla\u015ft\u0131r\u0131labilir; ve karbonil gruplar\u0131 hidrazonlar olu\u015fturabilir. Bile\u015fik ayr\u0131ca Fe(CO)3'\u00fc di\u011fer organik kimyasal substratlara verebilen bir reaktif olan (benzilidenaseton)Fe(CO)3 vermek i\u00e7in Fe2(CO)9 ile reaksiyona girebilir.<\/span><\/p>","protected":false},"excerpt":{"rendered":"

Benzilaseton: \u00d6zellikler, Uygulamalar ve \u00dcretim Y\u00f6ntemleri Benzilaseton 2550-26-7 Benzilaseton (IUPAC ad\u0131: 4-phenylbutan-2-one) tatl\u0131 \u00e7i\u00e7ek kokulu bir s\u0131v\u0131d\u0131r ve \u00e7i\u00e7eklerde (\u00f6rne\u011fin, \u00e7akal t\u00fct\u00fcn\u00fc, Nicotiana attenuata) en bol bulunan cezbedici bile\u015fik ve kakaonun u\u00e7ucu bile\u015fenlerinden biri olarak kabul edilir. Kavun sinekleri (Bactrocera cucurbitae) i\u00e7in yem olarak kullan\u0131l\u0131r [...]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nBenzylacetone: Properties, Applications, and Production Methods - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/benzi\u0307lasetonun-ozelli\u0307kleri\u0307-uygulamalari-ve-ureti\u0307m-yontemleri\u0307\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Benzylacetone: Properties, Applications, and Production Methods - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Benzylacetone: Properties, Applications, and Production Methods Benzylacetone\u00a02550-26-7 Benzylacetone (IUPAC name: 4-phenylbutan-2-one) is a liquid with a sweet floral odour and is considered to be the most abundant attractant compound in flowers (e.g., coyote tobacco, Nicotiana attenuata), and one of the volatile constituents of cocoa. 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