{"id":10658,"date":"2026-03-10T12:24:09","date_gmt":"2026-03-10T12:24:09","guid":{"rendered":"https:\/\/longchangextracts.com\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/"},"modified":"2026-03-10T12:24:09","modified_gmt":"2026-03-10T12:24:09","slug":"brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/","title":{"rendered":"Brefeldin A (CAS 20350-15-6): Bu Protein Ta\u015f\u0131ma \u0130nhibit\u00f6r\u00fc Hakk\u0131nda Kapsaml\u0131 Bir K\u0131lavuz"},"content":{"rendered":"<p><strong> Brefeldin A (BFA)<\/strong> modern h\u00fccre biyolojisi ve kanser ara\u015ft\u0131rmalar\u0131nda vazge\u00e7ilmez bir ara\u00e7 haline gelmi\u015f g\u00fc\u00e7l\u00fc bir mantar metabolitidir. CAS kay\u0131t numaras\u0131 <strong>20350-15-6<\/strong>, bu makrosiklik lakton, \u015fu mantar taraf\u0131ndan \u00fcretilir: <em>Penicillium brefeldianum<\/em> ve temel h\u00fccresel s\u00fcre\u00e7lere m\u00fcdahale etme konusundaki benzersiz yetene\u011fi sayesinde d\u00fcnya \u00e7ap\u0131nda ara\u015ft\u0131rmac\u0131lar\u0131n ilgisini \u00e7ekmi\u015ftir.<\/p><p>\u0130lk olarak 1950\u2019lerde ke\u015ffedilen Brefeldin A, ba\u015flang\u0131\u00e7ta potansiyel bir antibiyotik olarak incelenmi\u015fti. Ancak ara\u015ft\u0131rmac\u0131lar k\u0131sa s\u00fcrede, bu maddenin as\u0131l de\u011ferinin klinik uygulamalarda de\u011fil, bir <strong>etkili bir ara\u015ft\u0131rma arac\u0131<\/strong> h\u00fccresel protein ta\u015f\u0131ma mekanizmalar\u0131n\u0131n anla\u015f\u0131lmas\u0131 i\u00e7in. G\u00fcn\u00fcm\u00fczde, h\u00fccre i\u00e7i ta\u015f\u0131ma, apoptoz ve \u00e7e\u015fitli hastal\u0131k mekanizmalar\u0131n\u0131n incelenmesi amac\u0131yla d\u00fcnyan\u0131n d\u00f6rt bir yan\u0131ndaki laboratuvarlarda yayg\u0131n olarak kullan\u0131lmaktad\u0131r.<\/p><h2 class=\"wp-block-heading\">Brefeldin A nedir?<\/h2><p> Brefeldin A is a macrocyclic lactone with the molecular formula C\u2081\u2086H\u2082\u2084O\u2084 and a molecular weight of 280.36 g\/mol. This white to off-white crystalline powder is produced by the fungus <em>Penicillium brefeldianum<\/em> ve BFA, Ascotoxin, Cyanein, Decumbin ve Nectrolide gibi \u00e7e\u015fitli alternatif isimlerle bilinir.<\/p><p>Genellikle \u226598% safl\u0131k derecesine sahip olan Brefeldin A, etanol, DMSO ve metanolde \u00e7\u00f6z\u00fcn\u00fcr; bu \u00f6zelli\u011fi sayesinde h\u00fccre biyolojisi ara\u015ft\u0131rmalar\u0131nda \u00e7e\u015fitli laboratuvar uygulamalar\u0131 i\u00e7in uygundur.<\/p><h2 class=\"wp-block-heading\">Etki Mekanizmas\u0131: Brefeldin A Nas\u0131l Etki Eder?<\/h2><p>Brefeldin A\u2019n\u0131n temel etki mekanizmas\u0131, \u015fu yetene\u011fine dayanmaktad\u0131r: <strong>protein ta\u015f\u0131nmas\u0131n\u0131 engellemek<\/strong> endoplazmik retikulumdan (ER) Golgi aparat\u0131na. Bu s\u00fcre\u00e7, birka\u00e7 temel yol arac\u0131l\u0131\u011f\u0131yla ger\u00e7ekle\u015fir:<\/p><h3 class=\"wp-block-heading\">1. ADP-ribosilasyon fakt\u00f6r\u00fcn\u00fcn (ARF) inhibisyonu<\/h3><p> Brefeldin A, \u015fu \u015fekilde etki g\u00f6sterir: <strong>ADP-ribosilasyon fakt\u00f6r\u00fc (ARF) GTPazlar\u0131<\/strong>, bunlar h\u00fccre zarlar\u0131na kaplama proteinlerinin ba\u011flanmas\u0131 i\u00e7in hayati \u00f6neme sahiptir. Bu kaplama proteinleri (\u00f6zellikle COPI), proteinleri ER\u2019den Golgi\u2019ye ta\u015f\u0131yan ta\u015f\u0131ma vezik\u00fcllerinin olu\u015fumu i\u00e7in gereklidir.<\/p><h3 class=\"wp-block-heading\">2. Golgi yap\u0131s\u0131nda bozulma<\/h3><p>When cells are treated with Brefeldin A, the Golgi apparatus rapidly disassembles and merges with the endoplasmic reticulum. This dramatic structural change provides researchers with a visual indicator of the compound&#8217;s activity and allows for detailed studies of cellular organization.<\/p><h3 class=\"wp-block-heading\">3. Endoplazmik Retikulum Stresinin Tetiklenmesi<\/h3><p>Brefeldin A, protein ta\u015f\u0131nmas\u0131n\u0131 engelleyerek proteinlerin ER\u2019de birikmesine neden olur ve bu da \u015funa yol a\u00e7ar: <strong>ER stresi<\/strong>. Bu stres, katlanmam\u0131\u015f protein tepkisini (UPR) tetikler; bu da nihayetinde \u015funa yol a\u00e7abilir: <strong>apoptoz<\/strong> (programlanm\u0131\u015f h\u00fccre \u00f6l\u00fcm\u00fc).<\/p><h2 class=\"wp-block-heading\">Ba\u015fl\u0131ca Uygulamalar ve Kullan\u0131m Alanlar\u0131<\/h2><h3 class=\"wp-block-heading\">1. H\u00fccre Biyolojisi Ara\u015ft\u0131rmalar\u0131<\/h3><p> Brefeldin A, \u00f6ncelikle bir <strong>ara\u015ft\u0131rma arac\u0131<\/strong> h\u00fccre biyolojisinde:<\/p><ul><li><strong>Protein Ta\u015f\u0131n\u0131m\u0131 \u00c7al\u0131\u015fmalar\u0131:<\/strong> Ara\u015ft\u0131rmac\u0131lar, proteinlerin h\u00fccre i\u00e7inde nas\u0131l hareket etti\u011fini anlamak i\u00e7in BFA y\u00f6ntemini kullan\u0131yor<\/li><li><strong>Golgi Fonksiyonu Analizi:<\/strong> Bu bile\u015fik, bilim insanlar\u0131n\u0131n Golgi aparat\u0131n\u0131n yap\u0131s\u0131n\u0131 ve i\u015flevini incelemelerine yard\u0131mc\u0131 oluyor<\/li><li><strong>Vezik\u00fcl Ta\u015f\u0131n\u0131m\u0131 Ara\u015ft\u0131rmas\u0131:<\/strong> BFA, vezik\u00fcllerin nas\u0131l olu\u015ftu\u011fu ve h\u00fccresel y\u00fck\u00fc nas\u0131l ta\u015f\u0131d\u0131\u011f\u0131na dair bilgiler sunuyor<\/li><\/ul><!-- \/wp:list --><!-- wp:heading --><h3>2. Kanser Ara\u015ft\u0131rmalar\u0131 ve Tedavisi<\/h3><!-- \/wp:heading --><!-- wp:paragraph --><p>Brefeldin A\u2019n\u0131n en umut verici uygulamalar\u0131ndan biri \u015fudur: <strong>kanser ara\u015ft\u0131rmalar\u0131<\/strong>:<\/p><!-- wp:list --><ul><li><strong>Apoptozun Tetiklenmesi:<\/strong> BFA, \u00e7e\u015fitli kanser h\u00fccre hatlar\u0131nda apoptozu (h\u00fccre \u00f6l\u00fcm\u00fc) tetikler<\/li><li><strong>p53\u2019ten Ba\u011f\u0131ms\u0131z Etki:<\/strong> Bir\u00e7ok kemoterap\u00f6tik ajan\u0131n aksine, BFA, p53 durumundan ba\u011f\u0131ms\u0131z olarak apoptozu tetikleyebilir; bu da onu p53 mutasyonlu t\u00fcm\u00f6rlerin tedavisinde potansiyel olarak yararl\u0131 k\u0131lar<\/li><li><strong>Sinerjik Etkiler:<\/strong> Ara\u015ft\u0131rmalar, BFA\u2019n\u0131n di\u011fer kemoterapi ila\u00e7lar\u0131n\u0131n etkilerini art\u0131rabilece\u011fini g\u00f6stermektedir<\/li><\/ul><!-- \/wp:list --><!-- wp:heading --><h3>3. Antiviral Ara\u015ft\u0131rmalar<\/h3><!-- \/wp:heading --><!-- wp:paragraph --><p>Ara\u015ft\u0131rmalar, Brefeldin A\u2019n\u0131n \u015fu \u00f6zellikleri sergiledi\u011fini ortaya koymu\u015ftur: <strong>antiviral \u00f6zellikler<\/strong>:<\/p><!-- wp:list --><ul><li>Bu bile\u015fik, \u00e7e\u015fitli vir\u00fcslerin \u00e7o\u011falmas\u0131n\u0131 engelleyebilir<\/li><li>Vir\u00fcs proteinlerinin i\u015flenmesini ve ta\u015f\u0131nmas\u0131n\u0131 engeller<\/li><li>BFA, antiviral ila\u00e7 geli\u015ftirme ara\u015ft\u0131rmalar\u0131nda kullan\u0131lmaktad\u0131r<\/li><\/ul><!-- \/wp:list --><!-- wp:heading --><h3>4. \u0130mm\u00fcnoloji \u00c7al\u0131\u015fmalar\u0131<\/h3><!-- \/wp:heading --><!-- wp:paragraph --><p>\u0130mm\u00fcnolojik ara\u015ft\u0131rmalarda Brefeldin A \u015fu ama\u00e7larla kullan\u0131l\u0131r:<\/p><!-- wp:list --><ul><li>Sitokin salg\u0131lama yolaklar\u0131n\u0131 incelemek<\/li><li>Ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerinin i\u015flevini analiz etmek<\/li><li>Antijen sunum mekanizmalar\u0131n\u0131 ara\u015ft\u0131rmak<\/li><\/ul><!-- \/wp:list --><!-- wp:heading --><h3>5. CRISPR\/Cas9'un Etkinle\u015ftirilmesi<\/h3><!-- \/wp:heading --><!-- wp:paragraph --><p>Son zamanlarda yap\u0131lan ara\u015ft\u0131rmalar, Brefeldin A\u2019n\u0131n bir <strong>CRISPR\/Cas9 aktivat\u00f6r\u00fc<\/strong>, gen d\u00fczenleme deneylerinin verimlili\u011fini art\u0131rarak.<\/p><!-- \/wp:paragraph --><!-- wp:heading --><h2>Ara\u015ft\u0131rma Bulgular\u0131 ve Klinik Potansiyel<\/h2><!-- \/wp:heading --><!-- wp:heading --><h3>Kanserle M\u00fccadele Etkisi<\/h3><!-- \/wp:heading --><!-- wp:paragraph --><p>Multiple studies have demonstrated Brefeldin A&#8217;s potential anticancer properties:<\/p><!-- wp:list --><ul><li><strong>Prostat Kanseri:<\/strong> BFA, prostat kanseri h\u00fccrelerinde h\u00fccre d\u00f6ng\u00fcs\u00fcn\u00fc hedef alarak h\u00fccre b\u00fcy\u00fcmesini engeller<\/li><li><strong>N\u00f6roendokrin T\u00fcm\u00f6rler:<\/strong> Ara\u015ft\u0131rmalar, BFA\u2019n\u0131n kaspaz-3\u2019\u00fcn aktivasyonu yoluyla apoptozu tetikledi\u011fini g\u00f6stermektedir<\/li><li><strong>\u00c7e\u015fitli Kanser T\u00fcrleri:<\/strong> Ara\u015ft\u0131rmalar, \u00e7e\u015fitli kanser h\u00fccre hatlar\u0131na kar\u015f\u0131 sitotoksisite g\u00f6sterdi\u011fini ortaya koymaktad\u0131r<\/li><\/ul><!-- \/wp:list --><!-- wp:heading --><h3>ER Stresi ve Apoptoz<\/h3><!-- \/wp:heading --><!-- wp:paragraph --><p>BFA\u2019n\u0131n neden oldu\u011fu ER stresi ile apoptoz aras\u0131ndaki ili\u015fki kapsaml\u0131 bir \u015fekilde incelenmi\u015ftir:<\/p><!-- wp:list --><ul><li>ER\u2019deki protein birikimi, katlanmam\u0131\u015f protein tepkisini tetikler<\/li><li>Uzun s\u00fcreli ER stresi, apoptoz yoluyla h\u00fccre \u00f6l\u00fcm\u00fcne yol a\u00e7ar<\/li><li>Mitokondriyal yolaklar, BFA\u2019n\u0131n neden oldu\u011fu apoptozda rol oynar<\/li><\/ul><!-- \/wp:list --><!-- wp:heading --><h2>G\u00fcvenlik ve Kullan\u0131m<\/h2><!-- \/wp:heading --><!-- wp:paragraph --><p><strong>\u00d6nemli Not:<\/strong> Brefeldin A, yaln\u0131zca \u015fu ama\u00e7la sat\u0131lmaktad\u0131r: <strong>ara\u015ft\u0131rma ve laboratuvar ama\u00e7lar\u0131<\/strong>. Bu \u00fcr\u00fcn, insanlarda veya hayvanlarda te\u015fhis, tedavi veya klinik ama\u00e7larla kullan\u0131lmak \u00fczere tasarlanmam\u0131\u015ft\u0131r.<\/p><!-- \/wp:paragraph --><!-- wp:heading --><h3>G\u00fcvenlik \u00d6nlemleri<\/h3><!-- \/wp:heading --><!-- wp:paragraph --><p>Ara\u015ft\u0131rma ortam\u0131nda Brefeldin A ile \u00e7al\u0131\u015f\u0131rken:<\/p><!-- wp:list --><ul><li>Uygun ki\u015fisel koruyucu donan\u0131m (KKD) kullan\u0131n<\/li><li>\u00c7ekici kabin veya biyog\u00fcvenlik kabini i\u00e7inde \u00e7al\u0131\u015f\u0131n<\/li><li>Kurumsal g\u00fcvenlik kurallar\u0131na uyun<\/li><li>\u00dcreticinin \u00f6nerilerine uygun \u015fekilde saklay\u0131n<\/li><\/ul><!-- \/wp:list --><!-- wp:heading --><h3>Depolama<\/h3><!-- \/wp:heading --><!-- wp:list --><ul><li>-20 \u00b0C veya daha d\u00fc\u015f\u00fck bir s\u0131cakl\u0131kta saklay\u0131n\u0131z<\/li><li>I\u015f\u0131ktan koruyun<\/li><li>Kab\u0131 s\u0131k\u0131ca kapal\u0131 tutun<\/li><\/ul><!-- \/wp:list --><!-- wp:heading --><h2>Kimyasal \u00d6zellikler<\/h2><!-- \/wp:heading --><!-- wp:table --><figure class=\"wp-block-table\"><table><tbody><tr><td><strong>CAS Numaras\u0131<\/strong><\/td><td>20350-15-6<\/td><\/tr><tr><td><strong>Molek\u00fcler Form\u00fcl<\/strong><\/td><td>C\u2081\u2086H\u2082\u2084O\u2084<\/td><\/tr><tr><td><strong>Molek\u00fcler A\u011f\u0131rl\u0131k<\/strong><\/td><td>280,36 g\/mol<\/td><\/tr><tr><td><strong>G\u00f6r\u00fcn\u00fc\u015f<\/strong><\/td><td>Beyaz kristal toz<\/td><\/tr><tr><td><strong>Safl\u0131k<\/strong><\/td><td>\u226598%<\/td><\/tr><tr><td><strong>\u00c7\u00f6z\u00fcn\u00fcrl\u00fck<\/strong><\/td><td>Etanol, DMSO, Metanol<\/td><\/tr><tr><td><strong>Alternatif Adlar<\/strong><\/td><td>BFA, Askotoksin, Siyanein, Dekumbin, Nektrolid<\/td><\/tr><\/tbody><\/table><\/figure><!-- \/wp:table --><!-- wp:heading --><h2>Neden Brefeldin A\u2019m\u0131z\u0131 Tercih Etmelisiniz?<\/h2><!-- \/wp:heading --><!-- wp:list --><ul><li><strong>Y\u00fcksek Safl\u0131k:<\/strong> Brefeldin A \u00fcr\u00fcn\u00fcm\u00fcz, ara\u015ft\u0131rma s\u0131n\u0131f\u0131 teknik \u00f6zelliklerini kar\u015f\u0131lar veya a\u015far (\u226598%)<\/li><li><strong>Kalite Kontrol\u00fc Yap\u0131lm\u0131\u015ft\u0131r:<\/strong> Her parti, safl\u0131k ve biyolojik aktivite a\u00e7\u0131s\u0131ndan kalite testinden ge\u00e7irilir<\/li><li><strong>G\u00fcvenilir Tedarik:<\/strong> Devam eden ara\u015ft\u0131rma ihtiya\u00e7lar\u0131 i\u00e7in s\u00fcrekli eri\u015filebilirlik<\/li><li><strong>Teknik Destek:<\/strong> Bilim insanlar\u0131ndan olu\u015fan ekibimiz, sorular\u0131n\u0131z\u0131 yan\u0131tlamaya haz\u0131rd\u0131r<\/li><li><strong>Rekabet\u00e7i Fiyatland\u0131rma:<\/strong> Ara\u015ft\u0131rma kurumlar\u0131 i\u00e7in fabrikadan do\u011frudan fiyatland\u0131rma<\/li><\/ul><!-- \/wp:list --><!-- wp:paragraph --><p>D\u00fcnya \u00e7ap\u0131ndaki ila\u00e7 \u015firketlerine, fason \u00fcreticilere ve ara\u015ft\u0131rma kurumlar\u0131na birinci s\u0131n\u0131f kimyasal \u00fcr\u00fcnler ve \u00f6zel m\u00fc\u015fteri deste\u011fi sunuyoruz.<\/p><!-- \/wp:paragraph --><!-- wp:heading --><h2>S\u0131k Sorulan Sorular<\/h2><!-- \/wp:heading --><!-- wp:heading --><h3>Brefeldin A\u2019n\u0131n ba\u015fl\u0131ca kullan\u0131m alan\u0131 nedir?<\/h3><!-- \/wp:heading --><!-- wp:paragraph --><p>Brefeldin A\u2019n\u0131n ba\u015fl\u0131ca kullan\u0131m alan\u0131 \u015fudur: <strong>ara\u015ft\u0131rma arac\u0131<\/strong> h\u00fccre biyolojisinde protein ta\u015f\u0131ma mekanizmalar\u0131n\u0131 incelemek i\u00e7in. Laboratuvarlarda, proteinlerin h\u00fccre i\u00e7inde nas\u0131l hareket etti\u011fini anlamak ve apoptoz gibi h\u00fccresel s\u00fcre\u00e7leri incelemek amac\u0131yla yayg\u0131n olarak kullan\u0131lmaktad\u0131r.<\/p><!-- \/wp:paragraph --><!-- wp:heading --><h3>Brefeldin A, apoptozu nas\u0131l tetikler?<\/h3><!-- \/wp:heading --><!-- wp:paragraph --><p> Brefeldin A, a\u015fa\u011f\u0131dakileri tetikleyerek apoptozu ind\u00fckler: <strong>endoplazmik retikulum stresi<\/strong> protein ta\u015f\u0131n\u0131m\u0131n\u0131n engellenmesi yoluyla. Bu durum, yanl\u0131\u015f katlanm\u0131\u015f proteinlerin birikmesine yol a\u00e7ar, bu da katlanmam\u0131\u015f protein tepkisini tetikler ve nihayetinde h\u00fccre \u00f6l\u00fcm\u00fcne yol a\u00e7ar.<\/p><!-- \/wp:paragraph --><!-- wp:heading --><h3>Brefeldin A, insanlar i\u00e7in g\u00fcvenli midir?<\/h3><!-- \/wp:heading --><p>Hay\u0131r. Brefeldin A, <strong>sadece ara\u015ft\u0131rma ama\u00e7l\u0131<\/strong> ve insanlarda veya hayvanlarda tedavi ama\u00e7l\u0131 kullan\u0131m\u0131 onaylanmam\u0131\u015ft\u0131r. Bu, \u00f6nemli h\u00fccresel etkilere yol a\u00e7abilen g\u00fc\u00e7l\u00fc bir bile\u015fiktir ve yaln\u0131zca uygun laboratuvar ortamlar\u0131nda e\u011fitimli ara\u015ft\u0131rmac\u0131lar taraf\u0131ndan kullan\u0131lmal\u0131d\u0131r.<\/p><!-- \/wp:paragraph --><!-- wp:heading --><h3>Genellikle hangi konsantrasyonda Brefeldin A kullan\u0131l\u0131r?<\/h3><!-- \/wp:heading --><!-- wp:paragraph --><p>H\u00fccre k\u00fclt\u00fcr\u00fc deneylerinde, tipik \u00e7al\u0131\u015fma konsantrasyonlar\u0131 \u015fu aral\u0131kta de\u011fi\u015fmektedir: <strong>0,1 ila 10 \u03bcg\/mL<\/strong>, belirli uygulamaya ve h\u00fccre tipine ba\u011fl\u0131 olarak. Ara\u015ft\u0131rmac\u0131lar, kendi deneylerine \u00f6zel ko\u015fullar\u0131 optimize etmelidir.<\/p><!-- \/wp:paragraph --><!-- wp:heading --><h3>Brefeldin A t\u00fcm h\u00fccre t\u00fcrlerinde etkili midir?<\/h3><!-- \/wp:heading --><p>Brefeldin A\u2019n\u0131n etkileri farkl\u0131 h\u00fccre tipleri aras\u0131nda de\u011fi\u015fiklik g\u00f6sterebilir. Baz\u0131 h\u00fccreler, BFA\u2019n\u0131n neden oldu\u011fu apoptoza di\u011ferlerine g\u00f6re daha duyarl\u0131d\u0131r ve bu tepki, p53 durumu ve h\u00fccresel stres yan\u0131t yollar\u0131 gibi fakt\u00f6rlere ba\u011fl\u0131 olabilir.<\/p><!-- \/wp:paragraph --><!-- wp:paragraph --><em><strong>Yasal Uyar\u0131:<\/strong> Bu makale yaln\u0131zca bilgilendirme ama\u00e7l\u0131d\u0131r ve ara\u015ft\u0131rma ile e\u011fitim ama\u00e7l\u0131 kullan\u0131lmak \u00fczere haz\u0131rlanm\u0131\u015ft\u0131r. Brefeldin A, insanlarda veya hayvanlarda tan\u0131 veya tedavi ama\u00e7l\u0131 kullan\u0131lmamal\u0131d\u0131r.<\/em><!-- \/wp:paragraph -->","protected":false},"excerpt":{"rendered":"<p>Brefeldin A (BFA) is a powerful fungal metabolite that has become an indispensable tool in modern cell biology and cancer research. With the CAS registry number 20350-15-6, this macrocyclic lactone is produced by the fungus Penicillium brefeldianum and has captured the attention of researchers worldwide for its unique ability to interfere with fundamental cellular processes. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Brefeldin A (CAS 20350-15-6): A Comprehensive Guide to This Protein Transport Inhibitor - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Brefeldin A (CAS 20350-15-6): A Comprehensive Guide to This Protein Transport Inhibitor - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Brefeldin A (BFA) is a powerful fungal metabolite that has become an indispensable tool in modern cell biology and cancer research. With the CAS registry number 20350-15-6, this macrocyclic lactone is produced by the fungus Penicillium brefeldianum and has captured the attention of researchers worldwide for its unique ability to interfere with fundamental cellular processes. [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/longchangextracts.com\/tr\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/\" \/>\n<meta property=\"og:site_name\" content=\"China Chemical Manufacturer\" \/>\n<meta property=\"article:published_time\" content=\"2026-03-10T12:24:09+00:00\" \/>\n<meta name=\"author\" content=\"Longchang Chemical\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Yazan:\" \/>\n\t<meta name=\"twitter:data1\" content=\"Longchang Chemical\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tahmini okuma s\u00fcresi\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 dakika\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/longchangextracts.com\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/\",\"url\":\"https:\/\/longchangextracts.com\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/\",\"name\":\"Brefeldin A (CAS 20350-15-6): A Comprehensive Guide to This Protein Transport Inhibitor - China Chemical Manufacturer\",\"isPartOf\":{\"@id\":\"https:\/\/longchangextracts.com\/#website\"},\"datePublished\":\"2026-03-10T12:24:09+00:00\",\"dateModified\":\"2026-03-10T12:24:09+00:00\",\"author\":{\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\"},\"breadcrumb\":{\"@id\":\"https:\/\/longchangextracts.com\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/#breadcrumb\"},\"inLanguage\":\"tr\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/longchangextracts.com\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/longchangextracts.com\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/longchangextracts.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Brefeldin A (CAS 20350-15-6): A Comprehensive Guide to This Protein Transport Inhibitor\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/longchangextracts.com\/#website\",\"url\":\"https:\/\/longchangextracts.com\/\",\"name\":\"China Chemical Manufacturer\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/longchangextracts.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"tr\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\",\"name\":\"Longchang Chemical\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"tr\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"caption\":\"Longchang Chemical\"},\"description\":\"Longchang Chemical is the company publisher of chemical, ingredient and technical procurement information on longchangextracts.com. Publication responsibility rests with Shandong Longchang Chemical Co., Ltd. See the Authors &amp; Editorial Responsibility page for the scope of this company byline and correction contacts.\",\"sameAs\":[\"https:\/\/longchangextracts.com\/authors\/\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Brefeldin A (CAS 20350-15-6): Bu Protein Ta\u015f\u0131ma \u0130nhibit\u00f6r\u00fc Hakk\u0131nda Kapsaml\u0131 Bir K\u0131lavuz - \u00c7inli Kimya \u00dcreticisi","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/longchangextracts.com\/tr\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/","og_locale":"tr_TR","og_type":"article","og_title":"Brefeldin A (CAS 20350-15-6): A Comprehensive Guide to This Protein Transport Inhibitor - China Chemical Manufacturer","og_description":"Brefeldin A (BFA) is a powerful fungal metabolite that has become an indispensable tool in modern cell biology and cancer research. With the CAS registry number 20350-15-6, this macrocyclic lactone is produced by the fungus Penicillium brefeldianum and has captured the attention of researchers worldwide for its unique ability to interfere with fundamental cellular processes. [&hellip;]","og_url":"https:\/\/longchangextracts.com\/tr\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/","og_site_name":"China Chemical Manufacturer","article_published_time":"2026-03-10T12:24:09+00:00","author":"Longchang Chemical","twitter_card":"summary_large_image","twitter_misc":{"Yazan:":"Longchang Chemical","Tahmini okuma s\u00fcresi":"5 dakika"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/longchangextracts.com\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/","url":"https:\/\/longchangextracts.com\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/","name":"Brefeldin A (CAS 20350-15-6): Bu Protein Ta\u015f\u0131ma \u0130nhibit\u00f6r\u00fc Hakk\u0131nda Kapsaml\u0131 Bir K\u0131lavuz - \u00c7inli Kimya \u00dcreticisi","isPartOf":{"@id":"https:\/\/longchangextracts.com\/#website"},"datePublished":"2026-03-10T12:24:09+00:00","dateModified":"2026-03-10T12:24:09+00:00","author":{"@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869"},"breadcrumb":{"@id":"https:\/\/longchangextracts.com\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/#breadcrumb"},"inLanguage":"tr","potentialAction":[{"@type":"ReadAction","target":["https:\/\/longchangextracts.com\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/longchangextracts.com\/brefeldin-a-cas-20350-15-6-comprehensive-guide-protein-transport-inhibitor-2\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/longchangextracts.com\/"},{"@type":"ListItem","position":2,"name":"Brefeldin A (CAS 20350-15-6): A Comprehensive Guide to This Protein Transport Inhibitor"}]},{"@type":"WebSite","@id":"https:\/\/longchangextracts.com\/#website","url":"https:\/\/longchangextracts.com\/","name":"\u00c7in Kimyasal \u00dcreticisi","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/longchangextracts.com\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"tr"},{"@type":"Person","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869","name":"Longchang Chemical","image":{"@type":"ImageObject","inLanguage":"tr","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","caption":"Longchang Chemical"},"description":"Longchang Chemical, longchangextracts.com adresinde kimyasal, bile\u015fen ve teknik tedarik bilgilerini yay\u0131nlayan \u015firkettir. Yay\u0131n sorumlulu\u011fu Shandong Longchang Chemical Co., Ltd.\u2019ye aittir. Bu \u015firketin imza sat\u0131r\u0131n\u0131n kapsam\u0131 ve d\u00fczeltme i\u00e7in ileti\u015fim bilgileri hakk\u0131nda bilgi almak i\u00e7in \u201cYazarlar ve Yay\u0131n Sorumlulu\u011fu\u201d sayfas\u0131na bak\u0131n\u0131z.","sameAs":["https:\/\/longchangextracts.com\/authors\/"]}]}},"_links":{"self":[{"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/posts\/10658"}],"collection":[{"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/comments?post=10658"}],"version-history":[{"count":0,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/posts\/10658\/revisions"}],"wp:attachment":[{"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/media?parent=10658"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/categories?post=10658"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/longchangextracts.com\/tr\/wp-json\/wp\/v2\/tags?post=10658"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}