{"id":10034,"date":"2024-10-04T16:05:57","date_gmt":"2024-10-04T16:05:57","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=10034"},"modified":"2024-10-04T16:05:57","modified_gmt":"2024-10-04T16:05:57","slug":"vitamin-b12-2","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/tr\/vitamin-b12-2\/","title":{"rendered":"Besinsel Zenginle\u015ftirme i\u00e7in B12 Vitamini Nedir?"},"content":{"rendered":"

Besinsel Zenginle\u015ftirme i\u00e7in B12 Vitamini Nedir?<\/h1>\n

B12 Vitamini Nedir
\nB12 Vitamini (Siyanokobalamin), hayvansal protein fakt\u00f6r\u00fc olarak da bilinen siyanokobalamin olarak da bilinen suda \u00e7\u00f6z\u00fcnen bir vitamindir, siyanokobalamine benzer aktif maddeler i\u00e7eren bir grup vitamin i\u00e7in kullan\u0131lan genel bir terimdir. Metal iyonlar\u0131 i\u00e7eren suda \u00e7\u00f6z\u00fcnen tek vitamindir ve temel vitaminlerden biridir. B12 vitamininin sentetik \u00fcr\u00fcn\u00fc, kobalaminin ayr\u0131\u015fmas\u0131 s\u0131ras\u0131nda olu\u015fan siyanokobalamindir. \u00c7ok stabil olan k\u0131rm\u0131z\u0131 bir kristaldir ve g\u0131da takviyesi ve besin takviyesi i\u00e7in kullan\u0131l\u0131r. Bitki h\u00fccreleri B12 vitamini sentezleyemez, bu nedenle \u00e7o\u011fu bitkisel g\u0131da, hayvansal dokularda yo\u011funla\u015fan B12 vitamini i\u00e7ermez.
\nB12 vitamininin fizyolojik i\u015flevleri
\n1. Metiyonin (homosisteinden sentezlenir) ve kolin sentezi ile birlikte folik asit ve folik asit kullan\u0131m oran\u0131n\u0131n art\u0131r\u0131lmas\u0131, siyanokobalamin sentezi s\u00fcrecinde p\u00fcrin ve pirimidinlerin \u00fcretimi Metilkobalamin ve koenzim B12 gibi \u015fin baz \u00f6nc\u00fc maddeleri, bir\u00e7ok \u00f6nemli bile\u015fi\u011fin metilasyon s\u00fcrecinde yer al\u0131r. B12 vitamini eksikli\u011finde, metiltetrahidrofolattan metil gruplar\u0131n\u0131n transferi azal\u0131r, folik asidi kullan\u0131lamaz bir forma d\u00f6n\u00fc\u015ft\u00fcr\u00fcr ve folat eksikli\u011fine yol a\u00e7ar.
\n2. Sinir miyelin metabolizmas\u0131n\u0131n ve i\u015flevinin s\u00fcrd\u00fcr\u00fclmesi B12 vitamini eksik oldu\u011funda n\u00f6rolojik eksikliklere, omurilik dejenerasyonuna ve ciddi psikiyatrik semptomlara neden olabilir. B12 vitamini eksikli\u011fi periferik n\u00f6rite yol a\u00e7abilir. \u00c7ocuklarda B12 vitamini eksikli\u011finin erken belirtileri anormal ruh hali, donuk ifade, yava\u015f tepki ve son olarak anemidir.
\n3. Metilmalonil koenzim A'y\u0131, s\u00fcksinil koenzim A'n\u0131n hemoglobin senteziyle ili\u015fkili oldu\u011fu trikarboksilik asit d\u00f6ng\u00fcs\u00fcne kat\u0131lan s\u00fcksinil koenzim A'ya d\u00f6n\u00fc\u015ft\u00fcrerek k\u0131rm\u0131z\u0131 kan h\u00fccrelerinin geli\u015fimini ve olgunla\u015fmas\u0131n\u0131 destekler.
\n4. B12 vitamini deoksiribon\u00fckleik asit (DNA) sentezinde, ya\u011flar\u0131n, karbonhidratlar\u0131n ve proteinlerin metabolizmas\u0131nda rol oynar ve n\u00fckleik asitlerin ve proteinlerin sentezini art\u0131r\u0131r.
\nB12 vitamini eksikli\u011fi hastal\u0131\u011f\u0131
\n1. B12 vitamini eksikli\u011finin yayg\u0131n nedenleri (1) uzun s\u00fcreli vejetaryenler gibi yetersiz al\u0131m; (2) pankreas, mide, karaci\u011fer veya ba\u011f\u0131rsak hastal\u0131klar\u0131 gibi edinilmi\u015f malabsorpsiyon; (3) hamilelik, do\u011fum sonras\u0131 d\u00f6nem, tenyalar vb. gibi B12 vitamini i\u00e7in artan talep; (4) i\u00e7 fakt\u00f6rlerin do\u011fu\u015ftan eksikli\u011fi gibi B12 vitamininin metabolizma a\u015famas\u0131nda do\u011fu\u015ftan gelen engeller. (5) Farmakogenetik: \u00e7al\u0131\u015fmalar oral metforminin d\u00fc\u015f\u00fck serum B12 vitamini seviyelerine yol a\u00e7t\u0131\u011f\u0131n\u0131 bulmu\u015ftur.
\n2. B12 vitamini eksikli\u011finin yayg\u0131n hastal\u0131klar\u0131 B12 vitamini eksikli\u011fi temel olarak kan, metabolizma ve sinir sistemine yans\u0131r ve hiperhomosisteinemi (Hhcy), zararl\u0131 anemi, subakut kombine dejenerasyon, zihinsel depresyon, metilmalonik asidemi, vask\u00fcler demans ve Alzheimer hastal\u0131\u011f\u0131 ve di\u011fer hastal\u0131klara yol a\u00e7abilir.
\n3. B12 vitamini toksisitesi, 100\u03bcg'a kadar g\u00fcnl\u00fck oral raporlara g\u00f6re nispeten d\u00fc\u015f\u00fckt\u00fcr, \u00f6nemli bir advers reaksiyon yoktur. Not: B12 vitamininin beslenme durumu, serum B12 vitamini konsantrasyonu, serum holotranskobalamin II (holo Tc II), serum holobinding cochineal, serum homosistein ve metilmalonik asit test edilerek belirlenebilir.
\nReferans Al\u0131m Miktar\u0131 ve G\u0131da Kaynaklar\u0131
\n\u0130nsan v\u00fccudu \u00e7ok az B12 vitaminine ihtiya\u00e7 duyar. B12 vitamini i\u00e7in \u00d6nerilen Diyet \u00d6dene\u011fi (RDA), erken \u00e7ocukluk d\u00f6neminde g\u00fcnde 0,9 \u03bcg ile yeti\u015fkinlikte g\u00fcnde 2,4 \u03bcg aras\u0131nda de\u011fi\u015fmektedir ve bu da n\u00fcfusun 97,5%'sinin ihtiya\u00e7lar\u0131n\u0131 kar\u015f\u0131lamak i\u00e7in yeterlidir. Hamile kad\u0131nlar i\u00e7in RDA g\u00fcnde 6 \u03bcg'd\u0131r ve ya\u015fl\u0131lar i\u00e7in RDA art\u0131r\u0131lmam\u0131\u015f olsa da, B12 vitamini malabsorpsiyonuna yatk\u0131nd\u0131rlar ve B12 vitamini ile g\u00fc\u00e7lendirilmi\u015f g\u0131dalar veya takviyeler al\u0131mlar\u0131n\u0131 art\u0131rmalar\u0131 tavsiye edilir. B12 vitamini i\u00e7in \u00f6nerdi\u011fimiz AI yeti\u015fkinler i\u00e7in 2,4 \u03bcg\/g\u00fcn'd\u00fcr.
\nDiyetle al\u0131nan B12 vitamini hayvansal g\u0131dalardan elde edilir; ana besin kaynaklar\u0131 et, sakatat, bal\u0131k, k\u00fcmes hayvanlar\u0131, kabuklu deniz \u00fcr\u00fcnleri ve yumurta olup, s\u00fct ve s\u00fct \u00fcr\u00fcnlerinde daha az miktarda bulunur (Tablo 1). Bitkisel g\u0131dalar esasen B12 vitamini i\u00e7ermez.
\nTablo 1 Se\u00e7ilmi\u015f g\u0131dalar\u0131n B12 vitamini i\u00e7eri\u011fi (\u03bcg\/100g)<\/p>\n

\"\"<\/p>\n

Not: Ensminger AH et al. 1989.American Encyclopedia of Food and Nutrition Selected (5) Food Composition'da al\u0131nt\u0131lanm\u0131\u015ft\u0131r.
\nBesin takviyesi olarak B12 vitamini hangi g\u0131dalarda kullan\u0131labilir<\/p>\n

\"\"<\/p>","protected":false},"excerpt":{"rendered":"

What is Vitamin B12 for Nutritional Enrichment? What is Vitamin B12 Vitamin B12 (Cyanocobalamin) is a water-soluble vitamin also known as cyanocobalamin, also known as animal protein factor, is a general term for a group of vitamins containing active substances similar to cyanocobalamin. It is the only water-soluble vitamin that contains metal ions and is […]<\/p>","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[46],"tags":[],"yoast_head":"\nWhat is Vitamin B12 for Nutritional Enrichment? - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/tr\/vitamin-b12-2\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What is Vitamin B12 for Nutritional Enrichment? - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"What is Vitamin B12 for Nutritional Enrichment? 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