Calcium pyruvate (CAS 52009-14-0) is a compound formed by combining pyruvic acid with calcium. This unique chemical combination has gained significant attention in the health and supplement industries for its potential benefits in weight management and athletic performance. Pyruvate itself is a key intermediate in the glycolysis pathway, playing a crucial role in cellular energy production. When bound to calcium, it creates a stable compound that can be used as a dietary supplement.

What is Calcium Pyruvate?

Calcium pyruvate is the calcium salt of pyruvic acid, with the chemical formula Ca(C₃H₃O₃)₂. The compound appears as a white to off-white crystalline powder and is soluble in water. Pyruvate is naturally produced in the body during glycolysis—the process by which glucose is broken down to produce energy. As a supplement, calcium pyruvate is marketed primarily for its potential effects on metabolism, weight loss, and exercise performance.

The compound is classified under CAS number 52009-14-0 and is commonly available in various purity grades for research, pharmaceutical, and supplement applications. Its molecular weight is approximately 174.15 g/mol, and it typically contains about 23% elemental calcium by weight.

What Are the Benefits?

Calcium pyruvate has been studied for several potential health benefits, though research results have been mixed:

Weight Management Support

One of the most commonly cited benefits of calcium pyruvate is its potential to support weight loss efforts. Some studies suggest that pyruvate supplementation may help increase fat loss and improve body composition. The proposed mechanism involves enhanced lipolysis (fat breakdown) and possibly increased energy expenditure. However, it’s important to note that clinical evidence is not conclusive, and more research is needed to confirm these effects.

Exercise Performance Enhancement

Research has investigated calcium pyruvate’s potential ergogenic effects. Some studies have suggested that pyruvate supplementation might improve exercise capacity and delay fatigue. The theory is that additional pyruvate could enhance the body’s ability to produce energy during exercise. However, a study published in PubMed found that calcium pyruvate supplementation during training did not significantly affect body composition or exercise performance and may negatively affect some blood lipid levels.

Metabolic Support

As a key intermediate in energy metabolism, pyruvate plays a fundamental role in cellular processes. Some researchers have explored whether supplemental pyruvate could support metabolic function, though definitive clinical evidence is lacking.

Calcium Supplementation

Calcium pyruvate provides elemental calcium, which is essential for bone health, muscle function, nerve transmission, and blood clotting. The calcium in this compound may contribute to daily calcium intake requirements.

What Are the Uses?

Calcium pyruvate (CAS 52009-14-0) is used in various applications:

Besin Takviyeleri

The primary use of calcium pyruvate is in dietary supplement formulations. It is commonly found in:

• Weight management supplements
• Sports nutrition products
• Metabolic support formulas
• General health supplements

Pharmaceutical Applications

In pharmaceutical contexts, calcium pyruvate may be used in research and development of metabolic therapies. It serves as a pharmaceutical intermediate and is investigated for various therapeutic applications.

Food Additive

Calcium pyruvate may also be used as a food additive in some regions, serving as a calcium source and processing aid in certain food products.

Safety and Side Effects

When considering calcium pyruvate supplementation, it’s important to be aware of potential side effects:

• Gastrointestinal issues: The most commonly reported side effects include diarrhea, gas, and bloating. These symptoms appear to increase in severity with larger doses.
• Starting dose recommendation: It is advisable to start with the lowest dose and gradually increase if no adverse symptoms are observed.
• Long-term use: The safety of long-term calcium pyruvate supplementation has not been well established. Most studies have lasted six weeks or less.
• Drug interactions: Consult a healthcare provider before combining with medications, especially those affecting metabolism or calcium levels.

According to WebMD, pyruvate is “possibly safe” when used appropriately for up to six weeks. Side effects such as stomach upset, gas, bloating, and diarrhea may occur when large amounts are taken.

Chemical Specifications

Property	Değer
CAS Numarası	52009-14-0
Chemical Formula	Ca(C₃H₃O₃)₂
Moleküler Ağırlık	174.15 g/mol
Görünüş	Beyaz ila kirli beyaz kristal toz
Çözünürlük	Suda çözünür
Calcium Content	Approximately 23%

Frequently Asked Questions

Q: Does calcium pyruvate really work for weight loss?
A: The evidence for calcium pyruvate’s effectiveness for weight loss is mixed. Some early studies showed modest results, but more recent and better-controlled studies have not convincingly demonstrated efficacy. It should not be considered a magic solution for weight loss.

Q: How much calcium pyruvate should I take?
A: Dosing varies by product and individual. Many supplements recommend 1-3 grams daily, divided into multiple doses. It’s best to start with a lower dose and follow product-specific instructions or consult a healthcare provider.

Q: Is calcium pyruvate safe?
A: Calcium pyruvate is generally considered safe for short-term use (up to 6 weeks) at appropriate doses. However, gastrointestinal side effects are common, and long-term safety data is limited.

Q: Can I take calcium pyruvate with other supplements?
A: It may be taken with other supplements, but be mindful of total calcium intake. Consult a healthcare provider if taking multiple calcium-containing products.

Q: What’s the difference between pyruvate and calcium pyruvate?
A: Pyruvate refers to the pyruvate ion (C₃H₃O₃⁻), while calcium pyruvate is the calcium salt of pyruvic acid. Calcium pyruvate is the form typically used in supplements because it is more stable and provides additional calcium.

Why Choose Our Calcium Pyruvate?

When sourcing calcium pyruvate (CAS 52009-14-0) for your research or business needs, our company offers:

• High quality products: We provide calcium pyruvate meeting rigorous purity standards
• Consistent batch quality: Every batch is tested to ensure consistent composition and purity
• Technical documentation: Complete certificates of analysis and technical support
• Competitive pricing: Factory-direct pricing for both research and bulk quantities
• Reliable supply: Stable inventory for consistent availability
• Custom packaging: Options available from small research quantities to bulk orders

Contact us today to learn more about our calcium pyruvate products and how they can support your research or business needs.

Related Products

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• Calcium Levulinate – Calcium salt for supplements
• Calcium Orotate – Bioavailable calcium form
• API Products – Pharmaceutical active ingredients

This article provides general information about calcium pyruvate (CAS 52009-14-0) for educational and informational purposes. It is not medical advice. Consult a qualified healthcare professional before starting any supplement regimen.