{"id":10646,"date":"2026-03-10T04:16:46","date_gmt":"2026-03-10T04:16:46","guid":{"rendered":"https:\/\/longchangextracts.com\/camostat-mesilate-cas-59721-29-8-a-comprehensive-guide-to-this-potent-serine-protease-inhibitor\/"},"modified":"2026-03-10T04:16:46","modified_gmt":"2026-03-10T04:16:46","slug":"camostat-mesilate-cas-59721-29-8-a-comprehensive-guide-to-this-potent-serine-protease-inhibitor","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/ru\/camostat-mesilate-cas-59721-29-8-a-comprehensive-guide-to-this-potent-serine-protease-inhibitor\/","title":{"rendered":"Camostat Mesilate (CAS 59721-29-8): A Comprehensive Guide to This Potent Serine Protease Inhibitor"},"content":{"rendered":"<p>Camostat mesilate (also known as Camostat mesylate) is a synthetic serine protease inhibitor with the CAS number 59721-29-8. First described in scientific literature in 1981, this compound was initially researched for its potential in inhibiting skin tumors in mice. The compound is also known by its development code FOY-305 and has garnered significant attention in recent years due to its diverse pharmacological properties.<\/p>\n\n<p>Camostat mesilate works by inhibiting various serine proteases, including trypsin, plasmin, kallikrein, and thrombin. It also suppresses cholecystokinin (CCK) and pro-inflammatory cytokines, making it a compound of interest for multiple therapeutic applications.<\/p>\n\n<h2 class=\"wp-block-heading\">\u0425\u0438\u043c\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0441\u0432\u043e\u0439\u0441\u0442\u0432\u0430<\/h2>\n\n<ul><li><strong>\u041c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u0430\u044f \u0444\u043e\u0440\u043c\u0443\u043b\u0430<\/strong>: C\u2082\u2080H\u2082\u2082N\u2084O\u2085\u00b7CH\u2083SO\u2083H (or C\u2082\u2081H\u2082\u2086N\u2084O\u2088S)<\/li><li><strong>\u041c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u0430\u044f \u043c\u0430\u0441\u0441\u0430<\/strong>: 494.52 g\/mol<\/li><li><strong>\u041d\u043e\u043c\u0435\u0440 CAS<\/strong>: 59721-29-8<\/li><li><strong>\u0421\u0438\u043d\u043e\u043d\u0438\u043c\u044b<\/strong>: Camostat mesylate, FOY-305, 4-Guanidino-2-phenylbutyrylglycine ester mesylate<\/li><li><strong>\u0412\u043d\u0435\u0448\u043d\u0438\u0439 \u0432\u0438\u0434<\/strong>: Typically available as a white to off-white powder<\/li><\/ul>\n\n<h2 class=\"wp-block-heading\">What Are the Benefits?<\/h2>\n\n<p>Camostat mesilate offers several notable benefits that make it valuable in both clinical and research settings:<\/p>\n\n<h3 class=\"wp-block-heading\">1. Pancreatitis Treatment<\/h3>\n\n<p>Camostat mesilate has been used for the treatment of acute pancreatitis and chronic pancreatitis. Its ability to inhibit trypsin and other pancreatic proteases helps reduce pancreatic inflammation and damage.<\/p>\n\n<h3 class=\"wp-block-heading\">2. Anti-Inflammatory Properties<\/h3>\n\n<p>The compound exhibits potent anti-inflammatory effects by inhibiting pro-inflammatory cytokines. This mechanism makes it useful in managing various inflammatory conditions.<\/p>\n\n<h3 class=\"wp-block-heading\">3. COVID-19 Research<\/h3>\n\n<p>Camostat mesilate gained significant attention during the COVID-19 pandemic as a potential treatment for SARS-CoV-2 infection. Research showed it could inhibit the virus&#8217;s entry into cells by targeting host cell proteases.<\/p>\n\n<h3 class=\"wp-block-heading\">4. Liver Fibrosis Prevention<\/h3>\n\n<p>Studies have demonstrated that camostat mesilate can significantly attenuate liver fibrosis by reducing plasmin and TGF-beta levels, inhibiting hepatic stellate cell activation without causing significant systemic side effects.<\/p>\n\n<h3 class=\"wp-block-heading\">5. Anticancer Potential<\/h3>\n\n<p>Originally researched for skin tumor inhibition, camostat mesilate continues to be investigated for its potential anticancer properties due to its ability to inhibit various proteases involved in tumor progression and metastasis.<\/p>\n\n<h3 class=\"wp-block-heading\">6. Digestive Disorder Management<\/h3>\n\n<p>Clinical trials have shown that camostat mesilate is effective in managing dyspepsia associated with nonalcoholic mild pancreatic disease, with patients tolerating the treatment well.<\/p>\n\n<h2 class=\"wp-block-heading\">What Are the Uses?<\/h2>\n\n<p>Camostat mesilate is utilized in various applications:<\/p>\n\n<h3 class=\"wp-block-heading\">Pharmaceutical Applications<\/h3>\n\n<ul><li><strong>Acute and Chronic Pancreatitis<\/strong>: Primary therapeutic use<\/li><li><strong>COVID-19 Treatment<\/strong>: Investigational use<\/li><li><strong>Liver Disorders<\/strong>: Research for fibrosis treatment<\/li><li><strong>Digestive Health<\/strong>: Management of pancreatic insufficiency<\/li><\/ul>\n\n<h3 class=\"wp-block-heading\">Research Applications<\/h3>\n\n<ul><li><strong>Biochemical Research<\/strong>: As a serine protease inhibitor<\/li><li><strong>Drug Development<\/strong>: Template for developing new protease inhibitors<\/li><li><strong>Virology Research<\/strong>: Studies on viral entry mechanisms<\/li><\/ul>\n\n<h3 class=\"wp-block-heading\">\u041f\u0440\u043e\u043c\u044b\u0448\u043b\u0435\u043d\u043d\u043e\u0435 \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u0435<\/h3>\n\n<ul><li><strong>Pharmaceutical Manufacturing<\/strong>: Active pharmaceutical ingredient production<\/li><li><strong>Laboratory Reagents<\/strong>: Biochemical studies<\/li><\/ul>\n\n<h2 class=\"wp-block-heading\">Safety and Side Effects<\/h2>\n\n<p>Camostat mesilate has been generally well-tolerated in clinical studies:<\/p>\n\n<ul><li><strong>Common Side Effects<\/strong>: Mild gastrointestinal discomfort may occur<\/li><li><strong>Severity<\/strong>: Most adverse effects reported are mild in nature<\/li><li><strong>Clinical Trial Data<\/strong>: In studies with 200mg doses three times daily for two weeks, patients showed only mild side effects with no severe adverse reactions<\/li><li><strong>Tolerability<\/strong>: The compound demonstrates a favorable safety profile for long-term use<\/li><\/ul>\n\n<p>As with any pharmaceutical compound, proper handling and storage are essential. Camostat mesilate should be stored according to manufacturer specifications and handled by trained professionals.<\/p>\n\n<h2 class=\"wp-block-heading\">Chemical Specifications<\/h2>\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Property<\/strong><\/td><td><strong>\u0417\u043d\u0430\u0447\u0435\u043d\u0438\u0435<\/strong><\/td><\/tr><tr><td>\u041d\u043e\u043c\u0435\u0440 CAS<\/td><td>59721-29-8<\/td><\/tr><tr><td>\u041c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u0430\u044f \u043c\u0430\u0441\u0441\u0430<\/td><td>494.52 g\/mol<\/td><\/tr><tr><td>\u041c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u0430\u044f \u0444\u043e\u0440\u043c\u0443\u043b\u0430<\/td><td>C\u2082\u2080H\u2082\u2082N\u2084O\u2085\u00b7CH\u2083SO\u2083H<\/td><\/tr><tr><td>\u0412\u043d\u0435\u0448\u043d\u0438\u0439 \u0432\u0438\u0434<\/td><td>\u041f\u043e\u0440\u043e\u0448\u043e\u043a \u043e\u0442 \u0431\u0435\u043b\u043e\u0433\u043e \u0434\u043e \u0441\u0432\u0435\u0442\u043b\u043e-\u0431\u0435\u043b\u043e\u0433\u043e \u0446\u0432\u0435\u0442\u0430<\/td><\/tr><tr><td>\u0427\u0438\u0441\u0442\u043e\u0442\u0430<\/td><td>Typically \u226598%<\/td><\/tr><tr><td>\u0420\u0430\u0441\u0442\u0432\u043e\u0440\u0438\u043c\u043e\u0441\u0442\u044c<\/td><td>\u0412\u043e\u0434\u043e\u0440\u0430\u0441\u0442\u0432\u043e\u0440\u0438\u043c\u044b\u0439<\/td><\/tr><\/tbody><\/table><\/figure>\n\n<h2 class=\"wp-block-heading\">Frequently Asked Questions<\/h2>\n\n<h3 class=\"wp-block-heading\">What is Camostat Mesilate used for?<\/h3>\n\n<p>Camostat mesilate is primarily used for treating acute and chronic pancreatitis. It has also been investigated for COVID-19 treatment, liver fibrosis, and various inflammatory conditions.<\/p>\n\n<h3 class=\"wp-block-heading\">Is Camostat Mesilate safe?<\/h3>\n\n<p>Clinical studies have shown camostat mesilate to be well-tolerated with mild side effects. However, it should only be used under medical supervision.<\/p>\n\n<h3 class=\"wp-block-heading\">How does Camostat Mesilate work?<\/h3>\n\n<p>Camostat mesilate works by inhibiting serine proteases such as trypsin, plasmin, kallikrein, and thrombin. It also suppresses pro-inflammatory cytokines, providing its therapeutic effects.<\/p>\n\n<h3 class=\"wp-block-heading\">Where can I purchase Camostat Mesilate?<\/h3>\n\n<p>Camostat mesilate is available from chemical suppliers and pharmaceutical distributors. Ensure you source from reputable suppliers that provide quality documentation and SDS.<\/p>\n\n<h2 class=\"wp-block-heading\">Why Choose Our Camostat Mesilate?<\/h2>\n\n<p>When sourcing Camostat Mesilate (CAS 59721-29-8), partner with a trusted supplier committed to quality:<\/p>\n\n<ul><li><strong>High Purity<\/strong>: Our Camostat Mesilate meets rigorous quality standards (\u226598% purity)<\/li><li><strong>Technical Support<\/strong>: Our team provides comprehensive technical documentation and support<\/li><li><strong>Reliable Supply<\/strong>: Consistent availability for research and manufacturing needs<\/li><li><strong>Competitive Pricing<\/strong>: Cost-effective solutions for bulk orders<\/li><li><strong>Quality Assurance<\/strong>: Full SDS and certificate of analysis available<\/li><\/ul>\n\n<h2 class=\"wp-block-heading\">Related Products<\/h2>\n\n<p>If you&#8217;re interested in Camostat Mesilate, you may also be interested in our other protease inhibitors and pharmaceutical intermediates:<\/p>\n\n<ul><li><a href=\"https:\/\/longchangextracts.com\/ru\/adefovir-cas-106941-25-7-complete-guide-to-this-antiviral-compound\/\">Adefovir (CAS 106941-25-7)<\/a><\/li><li><a href=\"https:\/\/longchangextracts.com\/ru\/aloe-emodin-cas-481-72-1-a-comprehensive-guide-to-this-potent-anthraquinone-compound\/\">Aloe Emodin (CAS 481-72-1)<\/a><\/li><li><a href=\"https:\/\/longchangextracts.com\/ru\/baicalein-cas-491-67-8-a-comprehensive-guide-to-this-potent-flavonoid-compound\/\">Baicalein (CAS 491-67-8)<\/a><\/li><li><a href=\"https:\/\/longchangextracts.com\/ru\/baicalin-cas-21967-41-9-a-comprehensive-guide-to-this-potent-flavonoid-compound\/\">Baicalin (CAS 21967-41-9)<\/a><\/li><li><a href=\"https:\/\/longchangextracts.com\/ru\/esomeprazole-cas-119141-88-7-a-comprehensive-guide-to-this-potent-proton-pump-inhibitor\/\">Esomeprazole (CAS 119141-88-7)<\/a><\/li><\/ul>\n\n<em>This article is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional before using any pharmaceutical compound.<\/em>","protected":false},"excerpt":{"rendered":"<p>Camostat mesilate (also known as Camostat mesylate) is a synthetic serine protease inhibitor with the CAS number 59721-29-8. First described in scientific literature in 1981, this compound was initially researched for its potential in inhibiting skin tumors in mice. The compound is also known by its development code FOY-305 and has garnered significant attention in [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Camostat Mesilate (CAS 59721-29-8): A Comprehensive Guide to This Potent Serine Protease Inhibitor - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/ru\/camostat-mesilate-cas-59721-29-8-a-comprehensive-guide-to-this-potent-serine-protease-inhibitor\/\" \/>\n<meta property=\"og:locale\" content=\"ru_RU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Camostat Mesilate (CAS 59721-29-8): A Comprehensive Guide to This Potent Serine Protease Inhibitor - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Camostat mesilate (also known as Camostat mesylate) is a synthetic serine protease inhibitor with the CAS number 59721-29-8. 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