brefeldin a cas 20350-15-6

Chemical Name: Brefeldin A

CAS No: 20350-15-6

Molecular Formula: C16H24O4

Molecular Weight: 280.36

Chemical Structure:

Appearance: A white crystalline powder

Assay: 98%

Brefeldin A Typical Properties

Item	Specifications
Appearance	A white crystalline powder
Solubility	Soluble in methanol, chloroform
Water	≤3%
Heavy Metals	<20ppm
Total Impurities(HPLC)	≤2%
Purity(HPLC)	≥98%

Brefeldin A Usage

1. Brefeldin A, a commonly used protein transport inhibitor, specifically reversibly blocks the transport of proteins from the endoplasmic reticulum (ER) to the Golgi.

2. After Brefeldin A treatment, the Golgi apparatus is quickly destroyed and fused to the endoplasmic reticulum, which exhibits energy, temperature and microtubule dependence.

3. In mammals and yeast, Brefeldin A inhibition of protein transport from the endoplasmic reticulum to the Golgi apparatus may be achieved by a class of GTP-exchange factors that activate Afr1p GTPase.

4. Arf1p forms transport vesicles by recruiting coat proteins to the inner membrane of the cell.

Brefeldin APackaging and Shipping

Packing: Bottle

Delivery: Express or air

Brefeldin AStorage

A cool, ventilated, dry place.

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