{"id":9109,"date":"2024-08-15T18:40:48","date_gmt":"2024-08-15T18:40:48","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=9109"},"modified":"2024-08-15T18:40:48","modified_gmt":"2024-08-15T18:40:48","slug":"herba-sophorae","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/herba-sophorae\/","title":{"rendered":"A Herba Sophorae polifenolok k\u00e9miai \u00f6sszetev\u0151inek UPLC-Q-TOF-MS\/MS anal\u00edzise"},"content":{"rendered":"

A Herba Sophorae polifenolok k\u00e9miai \u00f6sszetev\u0151inek UPLC-Q-TOF-MS\/MS anal\u00edzise
\nA Mesona chinensis Benth. a Labiatae nemzets\u00e9g Mesona nemzets\u00e9g\u00e9be tartoz\u00f3, \u00c9szakkelet-Indi\u00e1ban, D\u00e9lkelet-\u00c1zsi\u00e1ban, Tajvanon, K\u00edn\u00e1ban, Fujianban, Guangdongban, Guangxiban \u00e9s Yunnanban elterjedt gy\u00f3gyn\u00f6v\u00e9ny. A hagyom\u00e1nyos k\u00ednai gy\u00f3gy\u00e1szatban a Liangfen f\u0171 \"t\u00fcnd\u00e9rf\u0171k\u00e9nt\" ismert, \u00e9s fanyar, \u00e9des, hideg, h\u0151tiszt\u00edt\u00f3, v\u00e9rh\u0171t\u0151 \u00e9s m\u00e9regtelen\u00edt\u0151 hat\u00e1s\u00fa. \u00c9lelmiszerr\u00e9, term\u00e9szetes eg\u00e9szs\u00e9g\u00fcgyi term\u00e9kk\u00e9, s\u0151t klinikai gy\u00f3gyszerr\u00e9 is fejlesztett\u00e9k. A megl\u00e9v\u0151 kutat\u00e1sok kimutatt\u00e1k, hogy gy\u00f6kerei, sz\u00e1ra, levelei \u00e9s vir\u00e1gai nagy mennyis\u00e9g\u0171 bioakt\u00edv anyagot tartalmaznak, k\u00f6zt\u00fck poliszacharidokat, flavonoidokat, terp\u00e9neket, vitaminokat \u00e9s fenolokat, amelyek magas t\u00e1pl\u00e1lkoz\u00e1si \u00e9s gy\u00f3gy\u00e1szati \u00e9rt\u00e9kkel b\u00edrnak.<\/p>\n

A fenolos vegy\u00fcletek fontos szerepet j\u00e1tszanak a n\u00f6v\u00e9nyek n\u00f6veked\u00e9s\u00e9ben, \u00e9s er\u0151s v\u00e9d\u0151hat\u00e1ssal b\u00edrnak az emberi szervezet k\u00fcl\u00f6nb\u00f6z\u0151 szerveire. A jelent\u00e9sek szerint a tud\u00f3sok a kutat\u00e1sok sor\u00e1n meg\u00e1llap\u00edtott\u00e1k, hogy a liangfen f\u0171 hipoglik\u00e9mi\u00e1s \u00e9s v\u00e9rnyom\u00e1scs\u00f6kkent\u0151 anyagokat tartalmaz, bele\u00e9rtve a \u03b2 - szitoszterint, stigmaszterint, \u03b1 - \u00e9s \u03b2 - amiloid feh\u00e9rj\u00e9ket, oleanolsavat, arisztolokinsavat \u00e9s \u03b2 - szitoszteringlikozidokat. Ugyanakkor a tud\u00f3sok kilenc akt\u00edv vegy\u00fcletet azonos\u00edtottak a liangfen f\u0171 vizes kivonat\u00e1b\u00f3l, k\u00f6zt\u00fck a kaempferolt, az apigenint, a k\u00e1v\u00e9savat, a protokatechuinsavat, az eug\u00e9nsavat, a vanillinsavat, a p-hidroxibenzoesavat, az oleanolsavat \u00e9s az ursolsavat. K\u00f6z\u00fcl\u00fck a k\u00e1v\u00e9sav, a protokatechuic sav \u00e9s a kaempferol a liangfen f\u0171 antioxid\u00e1ns aktivit\u00e1s\u00e1nak fontos \u00f6sszetev\u0151inek tekinthet\u0151k, bele\u00e9rtve az LDL oxid\u00e1ci\u00f3 \u00e9s a gyullad\u00e1s cs\u00f6kkent\u00e9s\u00e9t, ez\u00e1ltal v\u00e9delmet ny\u00fajtva a sz\u00edv- \u00e9s \u00e9rrendszeri betegs\u00e9gekkel szemben.<\/p>\n

Az ultranagy teljes\u00edtm\u00e9ny\u0171 folyad\u00e9kkromatogr\u00e1fi\u00e1s tandem-kvadrupolos rep\u00fcl\u00e9si id\u0151 t\u00f6megspektrometria (UPLC-Q-TOF-MS\/MS) technol\u00f3gia el\u0151nyei a nagy \u00e9rz\u00e9kenys\u00e9g, a nagy felbont\u00e1s, a nagy elv\u00e1laszt\u00e1si hat\u00e9konys\u00e1g \u00e9s a r\u00f6vid elemz\u00e9si id\u0151. Ugyanakkor a vegy\u00fcletek molekulat\u00f6meg\u00e9r\u0151l, elemi \u00f6sszet\u00e9tel\u00e9r\u0151l \u00e9s ionfragmentumair\u00f3l is inform\u00e1ci\u00f3t nyerhet, ami lehet\u0151v\u00e9 teszi a vegy\u00fcletek szerkezet\u00e9nek gyors meghat\u00e1roz\u00e1s\u00e1t. Sz\u00e9les k\u00f6rben haszn\u00e1lj\u00e1k a gy\u00f3gyszeranal\u00edzis ter\u00fclet\u00e9n. Jelenleg a Sophora japonica polifenolok \u00f6sszet\u00e9tele nem teljesen ismert. Ebben a k\u00eds\u00e9rletben az UPLC-Q-TOF-MS\/MS technol\u00f3gi\u00e1t haszn\u00e1lt\u00e1k a Sophora japonica k\u00e9miai \u00f6sszetev\u0151inek gyors \u00e9s \u00e1tfog\u00f3 min\u0151s\u00e9gi elemz\u00e9s\u00e9re, fontos hivatkoz\u00e1si alapot szolg\u00e1ltatva a Sophora japonica fenolos k\u00e9miai \u00f6sszetev\u0151inek tanulm\u00e1nyoz\u00e1s\u00e1hoz.<\/p>\n

Ez a tanulm\u00e1ny egy UPLC-Q-TOF-MS\/MS m\u00f3dszert hozott l\u00e9tre a Sophora japonica polifenolos \u00f6sszetev\u0151inek elemz\u00e9s\u00e9re. A t\u00f6megspektrometria nyers adatainak elemz\u00e9s\u00e9vel, bele\u00e9rtve a relat\u00edv molekulat\u00f6meget, a retenci\u00f3s id\u0151t, az elemi \u00f6sszet\u00e9telt, a fragmentumionokat \u00e9s egy\u00e9b inform\u00e1ci\u00f3kat, valamint a referencia standardokkal, adatb\u00e1zisokkal \u00e9s irodalmi jelent\u00e9sekkel kombin\u00e1lva 51 vegy\u00fcletet azonos\u00edtottak \u00e9s spekul\u00e1ltak. Meger\u0151s\u00edt\u00e9st nyert, hogy a Sophora japonica polifenolos komponensei f\u0151k\u00e9nt flavonoidokb\u00f3l, fenilpropanoid savb\u00f3l \u00e9s oligomerjeikb\u0151l \u00e1llnak, bele\u00e9rtve a koffeoil-hexozidot, a szalvianolsav F-et \u00e9s a szalvianolsav H apigenin-6-ot,8-di-C-hexozid\u3001 Chuanchenpi kivonat, nobiletin-3-O - \u03b2 - D-gl\u00fckozid, 20-deoxiszalvianolsav, 3-O-D-gl\u00fckopiranozil-platidigenin-metil\u00e9szter \u00e9s marstenacigenin A nem szerepelnek a k\u00ednai gy\u00f3gyn\u00f6v\u00e9nygy\u00f3gy\u00e1szat vonatkoz\u00f3 irodalm\u00e1ban. Ez a tanulm\u00e1ny azt sugallja, hogy ezt a kilenc vegy\u00fcletet el\u0151sz\u00f6r fedezt\u00e9k fel a k\u00ednai gy\u00f3gyn\u00f6v\u00e9nygy\u00f3gy\u00e1szatban. A kutat\u00e1si eredm\u00e9nyek megalapozz\u00e1k a gy\u00f3gyn\u00f6v\u00e9nygy\u00f3gy\u00e1szat hat\u00e9kony anyagainak alapkutat\u00e1s\u00e1t \u00e9s fejleszt\u00e9s\u00e9t, \u00e9s fontos ir\u00e1nymutat\u00f3 jelent\u0151s\u00e9ggel b\u00edrnak az \u00faj gy\u00f3gyszerek tov\u00e1bbi fejleszt\u00e9se szempontj\u00e1b\u00f3l.<\/p>","protected":false},"excerpt":{"rendered":"

A Herba Sophorae polifenolok k\u00e9miai \u00f6sszetev\u0151inek UPLC-Q-TOF-MS\/MS elemz\u00e9se A Mesona chinensis Benth. a Labiatae nemzets\u00e9g Mesona nemzets\u00e9g\u00e9be tartoz\u00f3 gy\u00f3gyn\u00f6v\u00e9ny, amely \u00c9szakkelet-Indi\u00e1ban, D\u00e9lkelet-\u00c1zsi\u00e1ban, Tajvanon, K\u00edn\u00e1ban, Fujianban, Guangdongban, Guangxiban \u00e9s Yunnanban elterjedt. A Liangfen Grass hagyom\u00e1nyos k\u00ednai gy\u00f3gyszerk\u00e9nt \"t\u00fcnd\u00e9rf\u0171k\u00e9nt\" ismert, \u00e9s a [...]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nUPLC-Q-TOF-MS\/MS Analysis of Chemical Components of Polyphenols in Herba Sophorae - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/herba-sophorae\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"UPLC-Q-TOF-MS\/MS Analysis of Chemical Components of Polyphenols in Herba Sophorae - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"UPLC-Q-TOF-MS\/MS Analysis of Chemical Components of Polyphenols in Herba Sophorae Mesona chinensis Benth. is a herb of the genus Mesona of Labiatae, distributed in northeast India, southeast Asia, Taiwan, China, Fujian, Guangdong, Guangxi and Yunnan of China. 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