{"id":9091,"date":"2024-08-15T18:32:54","date_gmt":"2024-08-15T18:32:54","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=9091"},"modified":"2024-08-15T18:32:54","modified_gmt":"2024-08-15T18:32:54","slug":"diarylpropanes-in-nutmeg","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/diarylpropanok-a-szerecsendioban\/","title":{"rendered":"A diarylpropanok gyullad\u00e1scs\u00f6kkent\u0151 hat\u00f3anyagai a szerecsendi\u00f3ban"},"content":{"rendered":"<p>A diarylpropanok gyullad\u00e1scs\u00f6kkent\u0151 hat\u00f3anyagai a szerecsendi\u00f3ban<br \/>\nA szerecsendi\u00f3 a Myristica fragrans, a Myristidae csal\u00e1dba tartoz\u00f3 n\u00f6v\u00e9ny sz\u00e1r\u00edtott magja. A K\u00ednai Gy\u00f3gyszerk\u00f6nyv 2015-\u00f6s kiad\u00e1s\u00e1ban szerepel. Funkci\u00f3i \u00e9s javallatai k\u00f6z\u00e9 tartozik a qi k\u00f6z\u00e9ps\u0151 \u00e1raml\u00e1s\u00e1nak felmeleg\u00edt\u00e9se, a belek \u00f6sszeh\u00faz\u00f3 hat\u00e1sa \u00e9s a hasmen\u00e9s meg\u00e1ll\u00edt\u00e1sa. A l\u00e9p- \u00e9s gyomorhi\u00e1ny \u00e9s a hideg, elh\u00faz\u00f3d\u00f3 hasmen\u00e9s, haspuffad\u00e1s \u00e9s hasi f\u00e1jdalom, valamint h\u00e1ny\u00e1s eset\u00e9n alkalmazz\u00e1k, ha kevesebbet eszik. A szakirodalmi jelent\u00e9sek szerint a szerecsendi\u00f3 f\u0151 k\u00e9miai \u00f6sszetev\u0151i a lignin, a benzofur\u00e1n \u00faj lignin \u00e9s a nem benzofur\u00e1n \u00faj lignin, m\u00edg a diarylprop\u00e1n \u00f6sszetev\u0151kr\u0151l sz\u00f3l\u00f3 jelent\u00e9sek viszonylag ritk\u00e1k. A szerecsendi\u00f3 k\u00e9miai \u00f6sszetev\u0151i, k\u00fcl\u00f6n\u00f6sen a fenolos komponensek biol\u00f3giai aktivit\u00e1sok sz\u00e9les sk\u00e1l\u00e1j\u00e1val rendelkeznek, \u00e9s a jelenlegi aktivit\u00e1skutat\u00e1s els\u0151sorban a gyullad\u00e1scs\u00f6kkent\u0151 \u00e9s daganatellenes aktivit\u00e1sokra \u00f6sszpontos\u00edt. Ezen k\u00edv\u00fcl vannak relev\u00e1ns jelent\u00e9sek a k\u00f6zponti idegrendszerre gyakorolt hat\u00e1sokr\u00f3l is, mint p\u00e9ld\u00e1ul a neuroprotekt\u00edv, szorong\u00e1sellenes, antibakteri\u00e1lis \u00e9s a cukorbetegs\u00e9g kezel\u00e9s\u00e9re.<\/p>\n<p>A gyullad\u00e1s bizony\u00edtottan gyakori patol\u00f3giai mechanizmus az autoimmun rendelleness\u00e9gek \u00e9s betegs\u00e9gek, p\u00e9ld\u00e1ul a daganatok kialakul\u00e1s\u00e1ban. Amikor az immunsejteket gyullad\u00e1sos medi\u00e1torok \u00e9s m\u00e1s anyagok stimul\u00e1lj\u00e1k, ez el\u0151seg\u00edti a nitrog\u00e9n-oxid-szint\u00e1z (iNOS) kiterjedt expresszi\u00f3j\u00e1t, nitrog\u00e9n-oxidot (NO) szabad\u00edt fel, \u00e9s immunv\u00e1laszt v\u00e1lt ki. Ez\u00e9rt az NO-termel\u00e9s g\u00e1tl\u00e1sa k\u00f6zvetlen indik\u00e1tor a vegy\u00fcletek gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1s\u00e1nak \u00e9rt\u00e9kel\u00e9s\u00e9re.<\/p>\n<p>A hagyom\u00e1nyos gyullad\u00e1scs\u00f6kkent\u0151 gy\u00f3gyszereknek, p\u00e9ld\u00e1ul a ciklooxigen\u00e1z-2 (COX-2) g\u00e1tl\u00f3knak mell\u00e9khat\u00e1saik vannak a sz\u00edv- \u00e9s \u00e9rrendszerre \u00e9s a gyomorny\u00e1lkah\u00e1rty\u00e1ra, ez\u00e9rt \u00faj gyullad\u00e1scs\u00f6kkent\u0151 gy\u00f3gyszerek kutat\u00e1s\u00e1ra \u00e9s fejleszt\u00e9s\u00e9re van sz\u00fcks\u00e9g. Tekintettel a szerecsendi\u00f3ban tal\u00e1lhat\u00f3 fenolos komponensek gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1s\u00e1r\u00f3l sz\u00f3l\u00f3 kor\u00e1bbi jelent\u00e9sekre \u00e9s az ugyanezen fenolos komponens, a diarylprop\u00e1n korl\u00e1tozott kutat\u00e1s\u00e1ra, a diarylprop\u00e1n k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek gazdag\u00edt\u00e1sa \u00e9s \u00faj, gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1s\u00fa vezet\u0151 vegy\u00fcletek felfedez\u00e9se \u00e9rdek\u00e9ben ebben a tanulm\u00e1nyban izol\u00e1lt\u00e1k, tiszt\u00edtott\u00e1k \u00e9s szerkezetileg azonos\u00edtott\u00e1k a diarylprop\u00e1n komponenst a szerecsendi\u00f3 gy\u00fcm\u00f6lcs aceton kivonat\u00e1nak etil-acet\u00e1t frakci\u00f3j\u00e1b\u00f3l, \u00e9s vizsg\u00e1lt\u00e1k az izol\u00e1lt vegy\u00fclet NO-termel\u00e9sre gyakorolt g\u00e1tl\u00f3 hat\u00e1s\u00e1t eg\u00e9r RAW264.7 makrof\u00e1gokban.<\/p>\n<p>Ez a cikk a szerecsendi\u00f3 gy\u00fcm\u00f6lcs\u00e9b\u0151l nyert 70% aceton kivonat etil-acet\u00e1t frakci\u00f3j\u00e1nak k\u00e9miai \u00f6sszet\u00e9tel\u00e9t vizsg\u00e1lta. \u00d6t diarylprop\u00e1nvegy\u00fcletet izol\u00e1ltak \u00e9s azonos\u00edtottak, amelyek k\u00f6z\u00fcl az 1. vegy\u00fclet \u00faj vegy\u00fclet volt. Az 1 vegy\u00fclet NO-termel\u00e9s g\u00e1tl\u00f3 aktivit\u00e1si tesztje azt mutatta, hogy az 1 vegy\u00fclet (IC50=4,00 \u03bc mol\/L) szignifik\u00e1nsan er\u0151sebb g\u00e1tl\u00f3 hat\u00e1ssal volt az NO-termel\u00e9sre eg\u00e9r RAW264.7 makrof\u00e1gokban, mint a pozit\u00edv kontroll L-NMMA (IC50=0,18 \u03bc mol\/L). A vizsg\u00e1lat eredm\u00e9nyei anyagi alapot ny\u00fajthatnak a hagyom\u00e1nyos k\u00ednai gy\u00f3gy\u00e1szatban haszn\u00e1lt szerecsendi\u00f3 gyullad\u00e1scs\u00f6kkent\u0151 c\u00e9l\u00fa gy\u00f3gy\u00e1szati felhaszn\u00e1l\u00e1s\u00e1nak kiterjeszt\u00e9s\u00e9hez.<\/p>","protected":false},"excerpt":{"rendered":"<p>A diarylpropanok gyullad\u00e1scs\u00f6kkent\u0151 hat\u00f3anyagai a szerecsendi\u00f3ban A szerecsendi\u00f3 a Myristica fragrans, a Myristidae csal\u00e1dba tartoz\u00f3 n\u00f6v\u00e9ny sz\u00e1r\u00edtott magja. A K\u00ednai Gy\u00f3gyszerk\u00f6nyv 2015-\u00f6s kiad\u00e1s\u00e1ban szerepel. Funkci\u00f3i \u00e9s javallatai k\u00f6z\u00e9 tartozik a qi k\u00f6z\u00e9ps\u0151 \u00e1raml\u00e1s\u00e1nak felmeleg\u00edt\u00e9se, a belek \u00f6sszeh\u00faz\u00f3 hat\u00e1sa \u00e9s a hasmen\u00e9s meg\u00e1ll\u00edt\u00e1sa. A l\u00e9p [...]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The anti-inflammatory active ingredients of diarylpropanes in nutmeg - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/diarylpropanok-a-szerecsendioban\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The anti-inflammatory active ingredients of diarylpropanes in nutmeg - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"The anti-inflammatory active ingredients of diarylpropanes in nutmeg Nutmeg belongs to the dried seed of Myristica fragrans, a plant in the family Myristidae. 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It is included in the 2015 edition of the Chinese Pharmacopoeia. Its functions and indications include warming the middle stream of qi, astringent intestines, and stopping diarrhea. 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