{"id":9061,"date":"2024-08-15T18:11:59","date_gmt":"2024-08-15T18:11:59","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=9061"},"modified":"2024-08-15T18:11:59","modified_gmt":"2024-08-15T18:11:59","slug":"danshen","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/danshen\/","title":{"rendered":"A Danshen alkalmaz\u00e1s\u00e1val \u00e9s mechanizmus\u00e1val kapcsolatos kutat\u00e1si eredm\u00e9nyek a m\u00e1jbetegs\u00e9gek megel\u0151z\u00e9s\u00e9ben \u00e9s kezel\u00e9s\u00e9ben"},"content":{"rendered":"<p>A Danshen alkalmaz\u00e1s\u00e1val \u00e9s mechanizmus\u00e1val kapcsolatos kutat\u00e1si eredm\u00e9nyek a m\u00e1jbetegs\u00e9gek megel\u0151z\u00e9s\u00e9ben \u00e9s kezel\u00e9s\u00e9ben<br \/>\nA Salvia miltiorrhiza a Lamiaceae csal\u00e1dba tartoz\u00f3 \u00e9vel\u0151 gy\u00f3gyn\u00f6v\u00e9ny, amely a Salvia miltiorrhiza Beg sz\u00e1r\u00edtott gy\u00f6kereib\u0151l \u00e9s riz\u00f3m\u00e1ib\u00f3l \u00e1ll. Hat\u00e1sai k\u00f6z\u00e9 tartozik a v\u00e9rkering\u00e9s el\u0151seg\u00edt\u00e9se \u00e9s a meridi\u00e1nok szab\u00e1lyoz\u00e1sa, a v\u00e9r h\u0171t\u00e9se \u00e9s a karbunkulus megsz\u00fcntet\u00e9se, a v\u00e9r pang\u00e1s\u00e1nak megsz\u00fcntet\u00e9se \u00e9s a f\u00e1jdalom enyh\u00edt\u00e9se, valamint a nyugtalans\u00e1g enyh\u00edt\u00e9se \u00e9s az elme megnyugtat\u00e1sa. A modern farmakol\u00f3giai vizsg\u00e1latok kimutatt\u00e1k, hogy a Danshenben l\u00e9v\u0151 tanshinone IIA, tanshinone, poliszacharidok, danshensu \u00e9s szalvianolsav k\u00fcl\u00f6nb\u00f6z\u0151 biol\u00f3giai aktivit\u00e1sokkal rendelkezik, bele\u00e9rtve a sz\u00edvizomzat v\u00e9delm\u00e9t, hipoglik\u00e9mi\u00e1s hat\u00e1sokat \u00e9s daganatellenes hat\u00e1sokat.<\/p>\n<p>A m\u00e1jbetegs\u00e9g, mint vil\u00e1gszerte elterjedt betegs\u00e9g, komoly vesz\u00e9lyt jelent az emberi eg\u00e9szs\u00e9gre. Ide tartozik els\u0151sorban a v\u00edrusos m\u00e1jgyullad\u00e1s, az alkoholos m\u00e1jbetegs\u00e9g, a gy\u00f3gyszer okozta m\u00e1jk\u00e1rosod\u00e1s, az autoimmun m\u00e1jbetegs\u00e9g, a m\u00e1jzsugor \u00e9s a m\u00e1jr\u00e1k. Az elm\u00falt \u00e9vekben a Danshent sz\u00e9les k\u00f6rben haszn\u00e1lt\u00e1k a m\u00e1jbetegs\u00e9gek megel\u0151z\u00e9s\u00e9re \u00e9s kezel\u00e9s\u00e9re, \u00e9s a tud\u00f3sok itthon \u00e9s k\u00fclf\u00f6ld\u00f6n kiterjedt \u00e9s m\u00e9lyrehat\u00f3 kutat\u00e1sokat v\u00e9geztek a Danshen hepatoprotekt\u00edv mechanizmus\u00e1r\u00f3l \u00e9s klinikai alkalmaz\u00e1s\u00e1r\u00f3l. Ez a cikk \u00e1ttekint\u00e9st ny\u00fajt a Danshen alkalmaz\u00e1s\u00e1r\u00f3l \u00e9s hepatoprotekt\u00edv mechanizmus\u00e1r\u00f3l a m\u00e1jbetegs\u00e9gek megel\u0151z\u00e9s\u00e9ben \u00e9s kezel\u00e9s\u00e9ben, azzal a c\u00e9llal, hogy elm\u00e9leti \u00fatmutat\u00e1st ny\u00fajtson a Danshen hepatoprotekt\u00edv gy\u00f3gyszerek fejleszt\u00e9s\u00e9hez \u00e9s klinikai alkalmaz\u00e1s\u00e1hoz.<\/p>\n<p>A Danshen komplex farmakol\u00f3giai tev\u00e9kenys\u00e9gek sz\u00e9les sk\u00e1l\u00e1j\u00e1val rendelkezik, bele\u00e9rtve a daganatellenes, antioxid\u00e1ns, gyomorfek\u00e9ly-ellenes, gyullad\u00e1scs\u00f6kkent\u0151, lipidcs\u00f6kkent\u0151, sz\u00edvizomv\u00e9d\u0151 \u00e9s vesev\u00e9delmet. Ezek k\u00f6z\u00fcl viszonylag t\u00f6bb jelent\u00e9s sz\u00f3l a Danshen alkalmaz\u00e1s\u00e1r\u00f3l a m\u00e1jfibr\u00f3zis \u00e9s a m\u00e1jr\u00e1k megel\u0151z\u00e9s\u00e9ben \u00e9s kezel\u00e9s\u00e9ben. Jelenleg kev\u00e9s irodalmi jelent\u00e9s van a gy\u00f3gyszer okozta m\u00e1jk\u00e1rosod\u00e1s megel\u0151z\u00e9s\u00e9r\u0151l \u00e9s kezel\u00e9s\u00e9r\u0151l Danshen-nel, \u00e9s a mechanizmus kutat\u00e1sa nem el\u00e9g m\u00e9ly.<\/p>\n<p>Az ut\u00f3bbi \u00e9vekben a kutat\u00e1sok kimutatt\u00e1k, hogy a m\u00e1jfibr\u00f3zis k\u00f3ros folyamata reverzibilis. A m\u00e1jfibr\u00f3zis korai szakasz\u00e1ban, megfelel\u0151 kezel\u00e9ssel a m\u00e1jfibr\u00f3zis teljesen visszaford\u00edthat\u00f3, \u00e9s a progresszi\u00f3ja enyh\u00edthet\u0151 vagy ak\u00e1r gy\u00f3gy\u00edthat\u00f3 is. A hagyom\u00e1nyos k\u00ednai orvosl\u00e1s jellemz\u0151i a t\u00f6bb \u00f6sszetev\u0151b\u0151l \u00e1ll\u00f3 \u00e9s t\u00f6bb l\u00e9pcs\u0151ben hat\u00f3 gy\u00f3gym\u00f3dok. A m\u00e1jfibr\u00f3zis kialakul\u00e1s\u00e1nak k\u00fcl\u00f6nb\u00f6z\u0151 szakaszaira k\u00e9pes hatni, \u00e9s a m\u00e1jfibr\u00f3zis elleni k\u00fczdelemben jelent\u0151sen jobb, mint a nyugati orvosl\u00e1s. R\u00e1ad\u00e1sul kevesebb toxikus mell\u00e9khat\u00e1ssal rendelkezik, \u00e9s mind belf\u00f6ld\u00f6n, mind nemzetk\u00f6zi szinten konszenzuss\u00e1 v\u00e1lt. Jelenleg a m\u00e1jbetegs\u00e9gek Danshen \u00e1ltali megel\u0151z\u00e9s\u00e9nek \u00e9s kezel\u00e9s\u00e9nek kutat\u00e1sa els\u0151sorban a m\u00e1jr\u00e1k megel\u0151z\u00e9s\u00e9re \u00e9s kezel\u00e9s\u00e9re \u00f6sszpontos\u00edt, \u00e9s viszonylag kev\u00e9s kutat\u00e1s foglalkozik a m\u00e1jfibr\u00f3zis elleni hat\u00e1s\u00e1val. A m\u00e1jfibr\u00f3zis a k\u00fcl\u00f6nb\u00f6z\u0151 kr\u00f3nikus m\u00e1jbetegs\u00e9gek sz\u00fcks\u00e9ges \u00fatvonala, \u00e9s a Danshen m\u00e1jfibr\u00f3zis-ellenes hat\u00e1s\u00e1nak tov\u00e1bbi kutat\u00e1sa nagy jelent\u0151s\u00e9ggel b\u00edr. A Danshen j\u00f3 ter\u00e1pi\u00e1s hat\u00e1st \u00e9rt el a m\u00e1jfibr\u00f3zis ellen, ami nagy el\u0151ny\u00f6ket \u00e9s \u00edg\u00e9retes kil\u00e1t\u00e1sokat mutat. A m\u00e1jfibr\u00f3zis elleni hat\u00e1s pontos mechanizmusa a j\u00f6v\u0151beni kutat\u00e1sok k\u00f6z\u00e9ppontj\u00e1ba ker\u00fcl.<\/p>\n<p>Mind a jelenlegi m\u0171t\u00e9tnek, mind a kemoter\u00e1pi\u00e1nak vannak bizonyos h\u00e1tr\u00e1nyai a m\u00e1jr\u00e1k kezel\u00e9s\u00e9ben. A hagyom\u00e1nyos k\u00ednai orvosl\u00e1s el\u0151nyei a betegek \u00e9letmin\u0151s\u00e9g\u00e9nek jav\u00edt\u00e1s\u00e1ban, a betegs\u00e9g progresszi\u00f3j\u00e1nak ellen\u0151rz\u00e9s\u00e9ben \u00e9s a t\u00fcnetek jav\u00edt\u00e1s\u00e1ban egyre ink\u00e1bb el\u0151t\u00e9rbe ker\u00fclnek. A Danshen megel\u0151zi \u00e9s kezeli a m\u00e1jdaganatokat a jel\u00e1tviteli \u00fatvonalak szab\u00e1lyoz\u00e1s\u00e1val, a tumorsejtciklus g\u00e1tl\u00e1s\u00e1val, a tumorsejtek apopt\u00f3zis\u00e1nak kiv\u00e1lt\u00e1s\u00e1val, valamint a tumorsejtek inv\u00e1zi\u00f3j\u00e1nak \u00e9s migr\u00e1ci\u00f3j\u00e1nak g\u00e1tl\u00e1s\u00e1val, \u00e9s bizonyos r\u00e1kellenes aktivit\u00e1st mutat. Jelenleg azonban f\u0151k\u00e9nt az egyes m\u00e1jr\u00e1kos sejtvonalakon alapul\u00f3 in vitro kutat\u00e1si k\u00eds\u00e9rletek vagy r\u00e1gcs\u00e1l\u00f3modellek szakasz\u00e1ban marad, \u00e9s a legt\u00f6bb felhaszn\u00e1lt t\u00e1rgy az in vitro teny\u00e9sztett m\u00e1jsejtekre vagy egerekre korl\u00e1toz\u00f3dik. A daganatellenes hat\u00e1s m\u00e1s m\u00e1jr\u00e1kos sejtvonalakon \u00e9s m\u00e1s \u00e1llatk\u00eds\u00e9rletekben viszonylag kicsi, \u00e9s a hat\u00e1smechanizmus nem el\u00e9g m\u00e9ly. Ez\u00e9rt nagy jelent\u0151s\u00e9ggel b\u00edr az \u00e1llatk\u00eds\u00e9rletes kutat\u00e1sok meger\u0151s\u00edt\u00e9se a Danshen m\u00e1jr\u00e1kellenes hat\u00e1sainak felt\u00e1r\u00e1s\u00e1ban, \u00e9s a modern m\u00f3dszerek, p\u00e9ld\u00e1ul a h\u00e1l\u00f3zati farmakol\u00f3gia \u00e9s a molekul\u00e1ris biol\u00f3gia alkalmaz\u00e1sa a hat\u00e1smechanizmus tanulm\u00e1nyoz\u00e1s\u00e1ra.<\/p>","protected":false},"excerpt":{"rendered":"<p>Research progress on the application and mechanism of Danshen in the prevention and treatment of liver diseases Salvia miltiorrhiza is a perennial herb in the family Lamiaceae, consisting of dried roots and rhizomes of Salvia miltiorrhiza Beg. It has the effects of promoting blood circulation and regulating meridians, cooling blood and eliminating carbuncles, removing blood [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Research progress on the application and mechanism of Danshen in the prevention and treatment of liver diseases - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/danshen\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research progress on the application and mechanism of Danshen in the prevention and treatment of liver diseases - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Research progress on the application and mechanism of Danshen in the prevention and treatment of liver diseases Salvia miltiorrhiza is a perennial herb in the family Lamiaceae, consisting of dried roots and rhizomes of Salvia miltiorrhiza Beg. It has the effects of promoting blood circulation and regulating meridians, cooling blood and eliminating carbuncles, removing blood [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/longchangextracts.com\/hu\/danshen\/\" \/>\n<meta property=\"og:site_name\" content=\"China Chemical Manufacturer\" \/>\n<meta property=\"article:published_time\" content=\"2024-08-15T18:11:59+00:00\" \/>\n<meta name=\"author\" content=\"longcha9\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Szerz\u0151:\" \/>\n\t<meta name=\"twitter:data1\" content=\"longcha9\" \/>\n\t<meta name=\"twitter:label2\" content=\"Becs\u00fclt olvas\u00e1si id\u0151\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 perc\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/longchangextracts.com\/danshen\/\",\"url\":\"https:\/\/longchangextracts.com\/danshen\/\",\"name\":\"Research progress on the application and mechanism of Danshen in the prevention and treatment of liver diseases - China Chemical Manufacturer\",\"isPartOf\":{\"@id\":\"https:\/\/longchangextracts.com\/#website\"},\"datePublished\":\"2024-08-15T18:11:59+00:00\",\"dateModified\":\"2024-08-15T18:11:59+00:00\",\"author\":{\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\"},\"breadcrumb\":{\"@id\":\"https:\/\/longchangextracts.com\/danshen\/#breadcrumb\"},\"inLanguage\":\"hu\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/longchangextracts.com\/danshen\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/longchangextracts.com\/danshen\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/longchangextracts.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research progress on the application and mechanism of Danshen in the prevention and treatment of liver diseases\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/longchangextracts.com\/#website\",\"url\":\"https:\/\/longchangextracts.com\/\",\"name\":\"China Chemical Manufacturer\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/longchangextracts.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"hu\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\",\"name\":\"longcha9\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"hu\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"caption\":\"longcha9\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Kutat\u00e1si el\u0151rehalad\u00e1s az alkalmaz\u00e1s \u00e9s a mechanizmus a Danshen a megel\u0151z\u00e9s \u00e9s a kezel\u00e9s a m\u00e1jbetegs\u00e9gek - K\u00edna Chemical Manufacturer","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/longchangextracts.com\/hu\/danshen\/","og_locale":"hu_HU","og_type":"article","og_title":"Research progress on the application and mechanism of Danshen in the prevention and treatment of liver diseases - China Chemical Manufacturer","og_description":"Research progress on the application and mechanism of Danshen in the prevention and treatment of liver diseases Salvia miltiorrhiza is a perennial herb in the family Lamiaceae, consisting of dried roots and rhizomes of Salvia miltiorrhiza Beg. It has the effects of promoting blood circulation and regulating meridians, cooling blood and eliminating carbuncles, removing blood [&hellip;]","og_url":"https:\/\/longchangextracts.com\/hu\/danshen\/","og_site_name":"China Chemical Manufacturer","article_published_time":"2024-08-15T18:11:59+00:00","author":"longcha9","twitter_card":"summary_large_image","twitter_misc":{"Szerz\u0151:":"longcha9","Becs\u00fclt olvas\u00e1si id\u0151":"3 perc"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/longchangextracts.com\/danshen\/","url":"https:\/\/longchangextracts.com\/danshen\/","name":"Kutat\u00e1si el\u0151rehalad\u00e1s az alkalmaz\u00e1s \u00e9s a mechanizmus a Danshen a megel\u0151z\u00e9s \u00e9s a kezel\u00e9s a m\u00e1jbetegs\u00e9gek - K\u00edna Chemical Manufacturer","isPartOf":{"@id":"https:\/\/longchangextracts.com\/#website"},"datePublished":"2024-08-15T18:11:59+00:00","dateModified":"2024-08-15T18:11:59+00:00","author":{"@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869"},"breadcrumb":{"@id":"https:\/\/longchangextracts.com\/danshen\/#breadcrumb"},"inLanguage":"hu","potentialAction":[{"@type":"ReadAction","target":["https:\/\/longchangextracts.com\/danshen\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/longchangextracts.com\/danshen\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/longchangextracts.com\/"},{"@type":"ListItem","position":2,"name":"Research progress on the application and mechanism of Danshen in the prevention and treatment of liver diseases"}]},{"@type":"WebSite","@id":"https:\/\/longchangextracts.com\/#website","url":"https:\/\/longchangextracts.com\/","name":"K\u00edna Vegyi Gy\u00e1rt\u00f3","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/longchangextracts.com\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"hu"},{"@type":"Person","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869","name":"longcha9","image":{"@type":"ImageObject","inLanguage":"hu","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","caption":"longcha9"}}]}},"_links":{"self":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/9061"}],"collection":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/comments?post=9061"}],"version-history":[{"count":1,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/9061\/revisions"}],"predecessor-version":[{"id":9062,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/9061\/revisions\/9062"}],"wp:attachment":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/media?parent=9061"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/categories?post=9061"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/tags?post=9061"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}