{"id":9059,"date":"2024-08-15T18:11:22","date_gmt":"2024-08-15T18:11:22","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=9059"},"modified":"2024-08-15T18:11:22","modified_gmt":"2024-08-15T18:11:22","slug":"tianming-jing","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/tianming-jing\/","title":{"rendered":"A Tianming Jing terpenoid komponenseinek \u00e9s tumorellenes aktivit\u00e1suknak a kutat\u00e1sa"},"content":{"rendered":"<p>A Tianming Jing terpenoid komponenseinek \u00e9s tumorellenes aktivit\u00e1suknak a kutat\u00e1sa<br \/>\nAz Asteraceae csal\u00e1dba tartoz\u00f3 Carpesium nemzets\u00e9gnek k\u00f6r\u00fclbel\u00fcl 21 faja van, amelyek t\u00f6bbs\u00e9ge \u00c1zsi\u00e1ban \u00e9s Eur\u00f3p\u00e1ban elterjedt. A Carpesium abrotanoides L., mint hagyom\u00e1nyos k\u00ednai gy\u00f3gyn\u00f6v\u00e9nyt \u00e9vel\u0151 gy\u00f3gyn\u00f6v\u00e9nyekkel, hossz\u00fa ideje haszn\u00e1lj\u00e1k D\u00e9lkelet-\u00c1zsia orsz\u00e1gaiban, p\u00e9ld\u00e1ul K\u00edn\u00e1ban, D\u00e9l-Kore\u00e1ban \u00e9s Jap\u00e1nban k\u00fcl\u00f6nb\u00f6z\u0151 betegs\u00e9gek kezel\u00e9s\u00e9re. A Compendium of Materia Medica feljegyzi, hogy a Tianming Jing \u00e9des, hideg \u00e9s nem m\u00e9rgez\u0151; javallatok k\u00f6z\u00e9 tartozik a v\u00e9rh\u00e1ny\u00e1s, torokduzzanat, ny\u00e1lka \u00e9s ny\u00e1l stagn\u00e1l\u00e1s, sz\u00e9lm\u00e9reg scrofula, sebek \u00e9s duzzanat, kerekesf\u00e9rgek \u00e9s t\u0171f\u00e9reg. A hazai \u00e9s k\u00fclf\u00f6ldi jelent\u00e9sek szerint ez a n\u00f6v\u00e9ny gazdag jellegzetes \u00f6sszetev\u0151kben, p\u00e9ld\u00e1ul monoterp\u00e9nekben, szeszkviterp\u00e9nekben, diterp\u00e9nekben \u00e9s fenolokban, \u00e9s gyakran hat\u00e9kony farmakol\u00f3giai tev\u00e9kenys\u00e9ggel rendelkezik, p\u00e9ld\u00e1ul gyullad\u00e1scs\u00f6kkent\u0151, gombaellenes, parazitaellenes, daganatellenes \u00e9s v\u00edrusellenes hat\u00e1ssal. A terp\u00e9nvegy\u00fcletek gazdag szerkezeti t\u00edpusokkal \u00e9s v\u00e1ltozatos biol\u00f3giai aktivit\u00e1sokkal rendelkeznek, mint p\u00e9ld\u00e1ul a szeszkviterp\u00e9nek, monoterp\u00e9nek stb. Fontos anyagi alapot biztos\u00edtanak a vezet\u0151 vegy\u00fcletek felfedez\u00e9s\u00e9hez, \u00e9s fontos alkalmaz\u00e1si \u00e9rt\u00e9kkel b\u00edrnak az \u00faj gy\u00f3gyszerek kifejleszt\u00e9s\u00e9hez.<\/p>\n<p>A Tianming Jing n\u00f6v\u00e9ny k\u00e9miai er\u0151forr\u00e1sainak tov\u00e1bbi tanulm\u00e1nyoz\u00e1sa \u00e9s a biol\u00f3giailag akt\u00edv k\u00e9miai \u00f6sszetev\u0151k keres\u00e9s\u00e9nek folytat\u00e1sa. Ez a tanulm\u00e1ny felt\u00e1rja a petr\u00f3leum\u00e9teres kivonat\u00e1nak k\u00e9miai \u00f6sszet\u00e9tel\u00e9t \u00e9s in vitro tumorellenes aktivit\u00e1s\u00e1t, amely elm\u00e9leti alapot ny\u00fajthat a hagyom\u00e1nyos k\u00ednai gy\u00f3gy\u00e1szati anyagok fejleszt\u00e9s\u00e9hez \u00e9s felhaszn\u00e1l\u00e1s\u00e1hoz a tumorellenes aktivit\u00e1s ter\u00fclet\u00e9n.<\/p>\n<p>K\u00edna hatalmas ter\u00fclettel \u00e9s b\u0151s\u00e9ges Asteraceae n\u00f6v\u00e9nyforr\u00e1sokkal rendelkezik, ami b\u0151s\u00e9ges anyagi forr\u00e1sokat biztos\u00edt sz\u00e1munkra az Asteraceae n\u00f6v\u00e9nyek m\u00e9lyrehat\u00f3 kutat\u00e1s\u00e1hoz. A Tianming Jing nemzets\u00e9g n\u00f6v\u00e9nyei v\u00e1ltozatos k\u00e9miai \u00f6sszet\u00e9tel\u00fck \u00e9s magas gy\u00f3gy\u00e1szati \u00e9rt\u00e9k\u00fck miatt mindig is a term\u00e9szetes term\u00e9kek kutat\u00e1s\u00e1nak egyik forr\u00f3 pontja voltak.<\/p>\n<p>Jelenleg viszonylag kev\u00e9s hazai \u00e9s k\u00fclf\u00f6ldi tud\u00f3s v\u00e9gzett kutat\u00e1st a Tianming Jing petr\u00f3leum\u00e9ter frakci\u00f3j\u00e1nak k\u00e9miai \u00f6sszet\u00e9tel\u00e9r\u0151l \u00e9s farmakol\u00f3giai hat\u00e1sair\u00f3l. A n\u00f6v\u00e9ny k\u00e9miai er\u0151forr\u00e1sainak tov\u00e1bbi tiszt\u00e1z\u00e1sa \u00e9rdek\u00e9ben szisztematikus tanulm\u00e1nyt v\u00e9gezt\u00fcnk a k\u00e9miai \u00f6sszet\u00e9tel\u00e9r\u0151l, \u00e9s el\u0151sz\u00f6r izol\u00e1ltunk 9 vegy\u00fcletet (k\u00f6zt\u00fck 5 menton-monoterp\u00e9nt, 3 laktonmentes szeszkviterp\u00e9nt \u00e9s 1 reduk\u00e1lt szeszkviterp\u00e9n-laktont) ebb\u0151l a n\u00f6v\u00e9nyb\u0151l. A 3-8 vegy\u00fcletet el\u0151sz\u00f6r izol\u00e1lt\u00e1k ebb\u0151l a n\u00f6v\u00e9nynemzets\u00e9gb\u0151l. A fenti vegy\u00fcletek daganatellenes aktivit\u00e1s\u00e1t MTS-m\u00f3dszerrel \u00e9rt\u00e9kelt\u00fck, \u00e9s az eredm\u00e9nyek azt mutatt\u00e1k, hogy mind a monoterp\u00e9nek, mind a szeszkviterp\u00e9nek bizonyos citotoxikus aktivit\u00e1ssal rendelkeznek. K\u00f6z\u00fcl\u00fck a 4. \u00e9s a 8. vegy\u00fcletr\u0151l els\u0151 \u00edzben der\u00fclt ki, hogy gyenge g\u00e1tl\u00f3 hat\u00e1st fejt ki \u00f6t hum\u00e1n tumorsejt prolifer\u00e1ci\u00f3j\u00e1ra: leuk\u00e9mia (HL60), t\u00fcd\u0151r\u00e1k (A549), m\u00e1jr\u00e1k (SMMC7721), eml\u0151r\u00e1k (MCF7) \u00e9s vastagb\u00e9lr\u00e1k (SW480); hasonl\u00f3an a 9. vegy\u00fclet is gyenge g\u00e1tl\u00f3 hat\u00e1st mutatott, ami \u00f6sszhangban van a kor\u00e1bbi kutat\u00e1si eredm\u00e9nyekkel. Ezen t\u00falmen\u0151en a 2. vegy\u00fclet el\u0151sz\u00f6r mutatott ki jelent\u0151s g\u00e1tl\u00f3 hat\u00e1st az MCF7 \u00e9s SW480 r\u00e1kos sejtek prolifer\u00e1ci\u00f3j\u00e1ra, 72% \u00e9s 81% g\u00e1tl\u00e1si r\u00e1t\u00e1val, 40 \u03bc M koncentr\u00e1ci\u00f3ban; Az el\u0151zetes szerkezet-aktivit\u00e1s kapcsolat elemz\u00e9s szerint a menton t\u00edpus\u00fa monoterp\u00e9nek 9. poz\u00edci\u00f3j\u00e1ban l\u00e9v\u0151 hidroxilcsoport akt\u00edv er\u0151s\u00edt\u0151 csoport lehet. Ez a tanulm\u00e1ny els\u0151 alkalommal t\u00e1rja fel a Tianmingjing akt\u00edv \u00f6sszetev\u0151it, amelyek g\u00e1tolj\u00e1k az eml\u0151r\u00e1ksejteket \u00e9s a vastagb\u00e9lr\u00e1ksejteket, megalapozva ezzel a tov\u00e1bbi gy\u00f3gyszerfejleszt\u00e9st \u00e9s a Tianmingjing er\u0151forr\u00e1sok felhaszn\u00e1l\u00e1s\u00e1t.<\/p>","protected":false},"excerpt":{"rendered":"<p>A Tianming Jing terpenoid komponenseinek \u00e9s tumorellenes aktivit\u00e1suknak kutat\u00e1sa Az Asteraceae csal\u00e1dba tartoz\u00f3 Carpesium nemzets\u00e9gnek k\u00f6r\u00fclbel\u00fcl 21 faja van, amelyek t\u00f6bbs\u00e9ge \u00c1zsi\u00e1ban \u00e9s Eur\u00f3p\u00e1ban elterjedt. A Carpesium abrotanoides L., mint hagyom\u00e1nyos k\u00ednai gy\u00f3gyn\u00f6v\u00e9nyt \u00e9vel\u0151 gy\u00f3gyn\u00f6v\u00e9nyekkel, m\u00e1r r\u00e9g\u00f3ta haszn\u00e1lj\u00e1k D\u00e9lkeleten [...]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Research on the terpenoid components of Tianming Jing and their anti-tumor activity - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/tianming-jing\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research on the terpenoid components of Tianming Jing and their anti-tumor activity - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Research on the terpenoid components of Tianming Jing and their anti-tumor activity There are approximately 21 species of the genus Carpesium in the Asteraceae family, most of which are distributed in Asia and Europe. 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Carpesium abrotanoides L., as a traditional Chinese medicinal herb with perennial herbs, has been used for a long time in Southeast [&hellip;]","og_url":"https:\/\/longchangextracts.com\/hu\/tianming-jing\/","og_site_name":"China Chemical Manufacturer","article_published_time":"2024-08-15T18:11:22+00:00","author":"longcha9","twitter_card":"summary_large_image","twitter_misc":{"Szerz\u0151:":"longcha9","Becs\u00fclt olvas\u00e1si id\u0151":"3 perc"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/longchangextracts.com\/tianming-jing\/","url":"https:\/\/longchangextracts.com\/tianming-jing\/","name":"Kutat\u00e1s a terpenoid komponensek Tianming Jing \u00e9s azok anti-tumor aktivit\u00e1s - K\u00edna Chemical Manufacturer","isPartOf":{"@id":"https:\/\/longchangextracts.com\/#website"},"datePublished":"2024-08-15T18:11:22+00:00","dateModified":"2024-08-15T18:11:22+00:00","author":{"@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869"},"breadcrumb":{"@id":"https:\/\/longchangextracts.com\/tianming-jing\/#breadcrumb"},"inLanguage":"hu","potentialAction":[{"@type":"ReadAction","target":["https:\/\/longchangextracts.com\/tianming-jing\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/longchangextracts.com\/tianming-jing\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/longchangextracts.com\/"},{"@type":"ListItem","position":2,"name":"Research on the terpenoid components of Tianming Jing and their anti-tumor activity"}]},{"@type":"WebSite","@id":"https:\/\/longchangextracts.com\/#website","url":"https:\/\/longchangextracts.com\/","name":"K\u00edna Vegyi Gy\u00e1rt\u00f3","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/longchangextracts.com\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"hu"},{"@type":"Person","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869","name":"longcha9","image":{"@type":"ImageObject","inLanguage":"hu","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","caption":"longcha9"}}]}},"_links":{"self":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/9059"}],"collection":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/comments?post=9059"}],"version-history":[{"count":1,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/9059\/revisions"}],"predecessor-version":[{"id":9060,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/9059\/revisions\/9060"}],"wp:attachment":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/media?parent=9059"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/categories?post=9059"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/tags?post=9059"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}