{"id":9031,"date":"2024-08-15T17:57:27","date_gmt":"2024-08-15T17:57:27","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=9031"},"modified":"2024-08-15T17:57:27","modified_gmt":"2024-08-15T17:57:27","slug":"artemisia-annua-3","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/artemisia-annua-3\/","title":{"rendered":"Az Artemisia annua f\u00f6ld feletti r\u00e9sz\u00e9nek k\u00e9miai \u00f6sszetev\u0151inek, antioxid\u00e1ns \u00e9s tirozin\u00e1z g\u00e1tl\u00f3 hat\u00e1sainak vizsg\u00e1lata"},"content":{"rendered":"<section>Az Artemisia annua f\u00f6ld feletti r\u00e9szeinek k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek, antioxid\u00e1ns \u00e9s tirozin\u00e1z g\u00e1tl\u00f3 hat\u00e1s\u00e1nak vizsg\u00e1lata. A tirozin\u00e1z jelenleg az egyetlen ismert enzim a melanin metabolizmus\u00e1ban, amely kulcsszerepet j\u00e1tszik a melanin bioszint\u00e9zis\u00e9ben, szab\u00e1lyozva a melanin k\u00e9pz\u0151d\u00e9s\u00e9t. A tirozin\u00e1z-aktivit\u00e1s \u00f6sszef\u00fcgg\u00e9sbe hozhat\u00f3 bizonyos pigment\u00e1ci\u00f3s b\u0151rbetegs\u00e9gekkel \u00e9s az arc melaszma kialakul\u00e1s\u00e1val. A fokozott aktivit\u00e1s olyan pigment\u00e1ci\u00f3s rendelleness\u00e9gekhez vezethet, mint a melaszma. Hazai \u00e9s k\u00fclf\u00f6ldi tud\u00f3sok gyakran haszn\u00e1lnak tirozin\u00e1z-g\u00e1tl\u00f3 vizsg\u00e1latokat a b\u0151r hiperpigment\u00e1ci\u00f3j\u00e1nak kezel\u00e9s\u00e9re szolg\u00e1l\u00f3 gy\u00f3gyszerek sz\u0171r\u00e9s\u00e9re. Az ut\u00f3bbi \u00e9vekben a tirozin\u00e1z aktivit\u00e1st g\u00e1tl\u00f3 anyagok kivon\u00e1sa term\u00e9szetes term\u00e9kekb\u0151l a feh\u00e9r\u00edt\u0151 \u00e9s sz\u00e9ps\u00e9g\u00e1pol\u00f3 kozmetikumok fejleszt\u00e9s\u00e9nek egyik m\u00f3dja lett mind hazai, mind nemzetk\u00f6zi szinten.<\/p>\n<p>A Blumea balsamifera DC. az Asteraceae csal\u00e1dba tartoz\u00f3 \u00e9vel\u0151 l\u00e1gysz\u00e1r\u00fa n\u00f6v\u00e9ny. Gy\u00f3gy\u00e1szati neve Diangd vob bvid, Da Feng Ai, Bing Ben Ai \u00e9s Jia Feng Ai n\u00e9ven is ismert. F\u0151leg Guizhou, Guangxi, Yunnan \u00e9s m\u00e1s r\u00e9gi\u00f3kban termesztik. A n\u00e9pi feljegyz\u00e9sek szerint a hat\u00e1sa az es\u00e9sek okozta s\u00e9r\u00fcl\u00e9sek, kel\u00e9sek, t\u00e1lyogok, ekc\u00e9ma, b\u0151rgyullad\u00e1s kezel\u00e9s\u00e9re, a pang\u00e1s \u00e9s a t\u0171z eloszlat\u00e1s\u00e1ra, a duzzanat \u00e9s a f\u00e1jdalom cs\u00f6kkent\u00e9s\u00e9re stb. szolg\u00e1l. Haszn\u00e1lj\u00e1k reum\u00e1s \u00edz\u00fcleti gyullad\u00e1s, sz\u00fcl\u00e9s ut\u00e1ni sz\u00e9lf\u00e1j\u00e1s, dysmenorrhoea \u00e9s m\u00e1s betegs\u00e9gek kezel\u00e9s\u00e9re. A Li, Zhuang, Miao \u00e9s m\u00e1s ter\u00fcleteken hossz\u00fa gy\u00f3gy\u00e1szati m\u00faltra tekintenek vissza. Az Artemisia argyi leveleib\u0151l \u00e9s \u00e1gaib\u00f3l Artemisia argyi por nyerhet\u0151, amely term\u00e9szetes j\u00e9gpelyhekk\u00e9 finom\u00edthat\u00f3, a mell\u00e9kterm\u00e9k pedig j\u00e9gpehelyolaj. A term\u00e9szetes borneol k\u00e9pes eloszlatni a stagn\u00e1l\u00f3 h\u0151t, megtiszt\u00edtani a h\u0151t \u00e9s enyh\u00edteni a f\u00e1jdalmat, valamint fel\u00e9breszteni az elm\u00e9t, ez\u00e9rt sz\u00e9les k\u00f6rben haszn\u00e1lj\u00e1k a gy\u00f3gyszeriparban. Az Artemisia argyi levelek nyersanyagait a \"Artemisia argyi szeletek\" kinyer\u00e9se \u00e9s el\u0151\u00e1ll\u00edt\u00e1sa ut\u00e1n \u00e1ltal\u00e1ban hullad\u00e9kmaradv\u00e1nyk\u00e9nt kezelik, ami nagy er\u0151forr\u00e1s-pazarl\u00e1st okoz. Az el\u0151zetes elemz\u00e9s azt mutatja, hogy ezek a marad\u00e9kok m\u00e9g mindig nagy mennyis\u00e9g\u0171 funkcion\u00e1lis \u00f6sszetev\u0151t, p\u00e9ld\u00e1ul flavonoidokat tartalmaznak. Ez\u00e9rt az Artemisia annua nem ill\u00e9kony \u00f6sszetev\u0151inek alapos tanulm\u00e1nyoz\u00e1sa \u00e9s gy\u00f3gyhat\u00e1s\u00e1nak felt\u00e1r\u00e1sa fontos tudom\u00e1nyos \u00e9s gyakorlati \u00e9rt\u00e9kkel b\u00edr. Kutat\u00f3csoportunk kor\u00e1bban m\u00e1r besz\u00e1molt az Artemisia annua egyes flavonoidjair\u00f3l \u00e9s azok antioxid\u00e1ns \u00e9s \u03b1 - gl\u00fckozid\u00e1z g\u00e1tl\u00f3 hat\u00e1s\u00e1r\u00f3l. Az Artemisia annua nem ill\u00e9kony \u00f6sszetev\u0151inek tov\u00e1bbi vizsg\u00e1lata \u00e9s a kozmetikai fejleszt\u00e9sben \u00e9s a pigment\u00e1lt b\u0151rbetegs\u00e9gekben val\u00f3 potenci\u00e1lis alkalmaz\u00e1sainak felt\u00e1r\u00e1sa \u00e9rdek\u00e9ben ez a tanulm\u00e1ny k\u00fcl\u00f6nb\u00f6z\u0151 kromatogr\u00e1fi\u00e1s \u00e9s spektroszk\u00f3piai technik\u00e1kat alkalmazott az Artemisia annua f\u00f6ld feletti r\u00e9sz\u00e9nek nem ill\u00e9kony \u00f6sszetev\u0151inek izol\u00e1l\u00e1s\u00e1ra, tiszt\u00edt\u00e1s\u00e1ra \u00e9s azonos\u00edt\u00e1s\u00e1ra. Tov\u00e1bb\u00e1 a DPPH-m\u00f3dszert \u00e9s a tirozin\u00e1z kataliz\u00e1lt levodopa oxid\u00e1ci\u00f3s sebess\u00e9g m\u00f3dszer\u00e9t haszn\u00e1lt\u00e1k a vegy\u00fcletek in vitro antioxid\u00e1ns \u00e9s tirozin\u00e1z g\u00e1tl\u00f3 aktivit\u00e1s\u00e1nak sz\u0171r\u00e9s\u00e9re.<\/p>\n<p>Ez a cikk ezt k\u00e9t szempontb\u00f3l vizsg\u00e1lja: antioxid\u00e1ns \u00e9s tirozin\u00e1z g\u00e1tl\u00f3 hat\u00e1s. Ebben a tanulm\u00e1nyban k\u00fcl\u00f6nb\u00f6z\u0151 kromatogr\u00e1fi\u00e1s m\u00f3dszereket alkalmaztak 18 vegy\u00fclet izol\u00e1l\u00e1s\u00e1ra \u00e9s tiszt\u00edt\u00e1s\u00e1ra az Artemisia l\u00e9gi r\u00e9szeib\u0151l. A 10., 14. \u00e9s 18. vegy\u00fcletet el\u0151sz\u00f6r izol\u00e1lt\u00e1k az Artemisia nemzets\u00e9g n\u00f6v\u00e9nyeib\u0151l, a 13. vegy\u00fcletet pedig el\u0151sz\u00f6r izol\u00e1lt\u00e1k Artemisi\u00e1b\u00f3l. Az aktivit\u00e1svizsg\u00e1lat eredm\u00e9nyei azt mutatt\u00e1k, hogy a 3-5, 7-12 \u00e9s 18 vegy\u00fcletek er\u0151s DPPH-gy\u00f6kfog\u00f3 k\u00e9pess\u00e9get mutattak, m\u00edg a 7, 13, 14, 16 \u00e9s 17 vegy\u00fcletek j\u00f3 tirozin\u00e1zg\u00e1tl\u00f3 hat\u00e1ssal rendelkeztek. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy a vegy\u00fclet DPPH-gy\u00f6kfog\u00f3 k\u00e9pess\u00e9ge \u00e9s a tirozin\u00e1z-inhibitor aktivit\u00e1sa k\u00f6z\u00f6tt kev\u00e9s \u00f6sszef\u00fcgg\u00e9s volt. Egyed\u00fcl a 7. vegy\u00fclet mutatott j\u00f3 aktivit\u00e1st mindk\u00e9t k\u00eds\u00e9rleti tesztben, \u00e9s a specifikus hat\u00e1smechanizmusa m\u00e9g tov\u00e1bbi kutat\u00e1sokat ig\u00e9nyel. A flavonoidok az antioxid\u00e1nsok er\u0151s oszt\u00e1ly\u00e1t alkotj\u00e1k, mint p\u00e9ld\u00e1ul a kvercetin, a luteolin \u00e9s a kvercetin, amelyek mind er\u0151s antioxid\u00e1ns tulajdons\u00e1gokkal rendelkeznek. Vannak kutat\u00e1si jelent\u00e9sek arr\u00f3l, hogy a 3-5, 7-9, 11-13 \u00e9s 18 vegy\u00fcletek er\u0151s DPPH gy\u00f6kfog\u00f3 k\u00e9pess\u00e9ggel rendelkeznek. Vannak olyan vizsg\u00e1latok, amelyek szerint a 4., 5., 7. \u00e9s 13. vegy\u00fclet j\u00f3 g\u00e1tl\u00f3 hat\u00e1ssal van a tirozin\u00e1zra, m\u00edg m\u00e1s vegy\u00fcletek tirozin\u00e1zra gyakorolt g\u00e1tl\u00f3 hat\u00e1s\u00e1r\u00f3l nem sz\u00e1moltak be. Ez a cikk szisztematikusan izol\u00e1lta \u00e9s tiszt\u00edtotta az Artemisia annua vegy\u00fcleteit, \u00e9s tanulm\u00e1nyozta antioxid\u00e1ns \u00e9s tirozin\u00e1z g\u00e1tl\u00f3 hat\u00e1sukat. A kutat\u00e1si eredm\u00e9nyek tudom\u00e1nyos alapot \u00e9s elm\u00e9leti t\u00e1mogat\u00e1st ny\u00fajtanak az Artemisia annua er\u0151forr\u00e1sainak tov\u00e1bbi alkalmaz\u00e1s\u00e1hoz az antioxid\u00e1ns \u00e9s a tirozin\u00e1z g\u00e1tl\u00e1s\u00e1ban, valamint n\u00e9h\u00e1ny \u00f6tletet \u00e9s ir\u00e1nyt adnak az Artemisia annua fejleszt\u00e9s\u00e9hez \u00e9s alkalmaz\u00e1s\u00e1hoz az emberi pigmentes b\u0151rbetegs\u00e9gek \u00e9s a napi k\u00e9miai term\u00e9kek ter\u00fclet\u00e9n.<\/p>\n<\/section>\n<section>&nbsp;<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>Research on the chemical composition and antioxidant and tyrosinase inhibitory activities of aboveground parts of Artemisia annua. Tyrosinase is currently the only known enzyme in melanin metabolism that plays a key role in melanin biosynthesis, controlling melanin formation. Tyrosinase activity is associated with certain pigmentary skin diseases and the development of facial melasma. Increased activity [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Research on the Chemical Components and Antioxidant and Tyrosinase Inhibition Activities of the Aboveground Part of Artemisia annua - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/artemisia-annua-3\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research on the Chemical Components and Antioxidant and Tyrosinase Inhibition Activities of the Aboveground Part of Artemisia annua - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Research on the chemical composition and antioxidant and tyrosinase inhibitory activities of aboveground parts of Artemisia annua. Tyrosinase is currently the only known enzyme in melanin metabolism that plays a key role in melanin biosynthesis, controlling melanin formation. Tyrosinase activity is associated with certain pigmentary skin diseases and the development of facial melasma. 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