{"id":8673,"date":"2024-08-14T18:58:40","date_gmt":"2024-08-14T18:58:40","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=8673"},"modified":"2024-08-14T18:58:40","modified_gmt":"2024-08-14T18:58:40","slug":"soil-fungi-aspergillus-fumigatus","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/talajgombak-aspergillus-fumigatus\/","title":{"rendered":"Az Aspergillus fumigatus talajgomb\u00e1k szil\u00e1rd ferment\u00e1ci\u00f3s term\u00e9keinek k\u00e9miai \u00f6sszet\u00e9tele \u00e9s antioxid\u00e1ns aktivit\u00e1sa"},"content":{"rendered":"

Az Aspergillus fumigatus talajgomb\u00e1k szil\u00e1rd ferment\u00e1ci\u00f3s term\u00e9keinek k\u00e9miai \u00f6sszet\u00e9tele \u00e9s antioxid\u00e1ns aktivit\u00e1sa
\nAz ut\u00f3bbi \u00e9vekben a talajgomb\u00e1k diverzit\u00e1s\u00e1nak kutat\u00e1sa sz\u00e9les k\u00f6r\u0171 figyelmet kapott. A talaj b\u0151s\u00e9ges mikrobi\u00e1lis er\u0151forr\u00e1sokat tartalmaz, \u00e9s a F\u00f6ld egyik leg\u00f6sszetettebb mikrobi\u00e1lis \u00f6kosziszt\u00e9m\u00e1ja. A gomb\u00e1k, a talaj \u00e9s a n\u00f6v\u00e9nyi gy\u00f6kerek k\u00f6z\u00f6tti szoros kapcsolatnak k\u00f6sz\u00f6nhet\u0151en k\u00f6z\u00f6sen vesznek r\u00e9szt a t\u00e1panyagok felsz\u00edv\u00f3d\u00e1s\u00e1ban, meg\u0151rz\u00e9s\u00e9ben \u00e9s k\u00f6rforg\u00e1s\u00e1ban, valamint egyedi anyagcsere-\u00fatvonalakkal rendelkeznek, amelyek struktur\u00e1lisan \u00fajszer\u0171 \u00e9s biol\u00f3giailag akt\u00edv anyagcsereterm\u00e9kek el\u0151\u00e1ll\u00edt\u00e1s\u00e1t eredm\u00e9nyezik. Az Aspergillus fumigatus talajgomba k\u00e9miai \u00f6sszet\u00e9tel\u00e9r\u0151l \u00e9s aktivit\u00e1s\u00e1r\u00f3l m\u00e1r besz\u00e1moltak. Mohamad \u00e9s munkat\u00e1rsai 8 vegy\u00fcletet izol\u00e1ltak \u00e9s azonos\u00edtottak az Aspergillus fumigatus 3T-EGY talajgomba m\u00e1sodlagos metabolitjaib\u00f3l. K\u00f6z\u00fcl\u00fck a Juglathrakinon A-5-O-D-Rhodosamine (4 \u2032 \u2192 1 \u2032) -2-deoxy-D-gl\u00fck\u00f3z (4 \u2032 \u2192 1 \u2032) - inerulose B vegy\u00fclet m\u00e9rs\u00e9kelt in vitro antibakteri\u00e1lis aktivit\u00e1ssal rendelkezik Staphylococcus aureus, Pseudomonas aeruginosa \u00e9s Candida albicans ellen. Liu \u00e9s munkat\u00e1rsai egy \u00faj szeszkviterp\u00e9n-sz\u00e1rmaz\u00e9kot izol\u00e1ltak a tengerparti s\u00f3s talajban \u00e9l\u0151 Aspergillus niger gomb\u00e1b\u00f3l, amelyet pergiketonnak neveztek el. Ez a vegy\u00fclet citotoxicit\u00e1st mutat a HL-60 \u00e9s A549 sejtekkel szemben, 12,4 \u00e9s 22,1 \u03bc M IC50 \u00e9rt\u00e9kkel. Liang \u00e9s munkat\u00e1rsai meg\u00e1llap\u00edtott\u00e1k, hogy az Aspergillus fumigatus talajgomba egy rendk\u00edv\u00fcl akt\u00edv vashordoz\u00f3 t\u00f6rzs, amely nem g\u00e1tolja a n\u00f6v\u00e9nyi patog\u00e9n aktivit\u00e1st, de ferment\u00e1lt kivonata jelent\u0151sen el\u0151seg\u00edti a talaj biol\u00f3giai aktivit\u00e1s\u00e1t. E tanulm\u00e1ny korai szakasz\u00e1ban az Ailao Mountain National Nature Reserve v\u00f6lgy\u00e9b\u0151l sz\u00e1rmaz\u00f3 Aspergillus niger talajgomba szil\u00e1rd ferment\u00e1ci\u00f3s termeszt\u00e9s\u00e9t v\u00e9gezt\u00e9k. Meg\u00e1llap\u00edtottuk, hogy mer\u00e9sz anyaga DPPH (IC50=3,3mg\/ml), ABTS+ (IC50=0,094mg\/ml) \u00e9s OH gy\u00f6k\u00f6k (IC50=1,8mg\/ml) ellen kifejtett g\u00e1tl\u00f3 hat\u00e1st. Ez\u00e9rt ez a tanulm\u00e1ny k\u00e9miai \u00f6sszet\u00e9tel-kutat\u00e1st \u00e9s antioxid\u00e1ns aktivit\u00e1svizsg\u00e1latot v\u00e9gzett a talajgomb\u00e1k etil-acet\u00e1t r\u00e9teg\u00e9nek ferment\u00e1lt kivonat\u00e1n, megalapozva ezzel a t\u00f6rzs hat\u00f3anyagainak j\u00f6v\u0151beli fejleszt\u00e9s\u00e9t \u00e9s felhaszn\u00e1l\u00e1s\u00e1t.<\/p>\n

Ebben a tanulm\u00e1nyban 13 vegy\u00fcletet izol\u00e1ltak \u00e9s azonos\u00edtottak az Aspergillus niger talajgomba etil-acet\u00e1t r\u00e9teg\u00e9b\u0151l szil\u00e1rd \u00e1llapot\u00fa ferment\u00e1ci\u00f3s kult\u00fara seg\u00edts\u00e9g\u00e9vel. K\u00f6z\u00fcl\u00fck az 1., 5., 8., 11., 12. \u00e9s 13. vegy\u00fclet mind poliketid vegy\u00fclet volt, a 6., 7., 9. \u00e9s 10. vegy\u00fclet szteroid, a 3. \u00e9s 4. vegy\u00fclet pedig egy\u00e9b t\u00edpus\u00fa. K\u00f6z\u00fcl\u00fck a 6. vegy\u00fclet kiv\u00e9tel\u00e9vel az \u00f6sszes t\u00f6bbi vegy\u00fcletet el\u0151sz\u00f6r izol\u00e1lt\u00e1k e t\u00f6rzs szil\u00e1rd ferment\u00e1ci\u00f3s term\u00e9k\u00e9b\u0151l. Az Aspergillus niger talajgomb\u00e1b\u00f3l izol\u00e1lt \u00e9s azonos\u00edtott vegy\u00fcletek f\u0151k\u00e9nt poliketidek \u00e9s szteroidok, \u00e9s antioxid\u00e1ns aktivit\u00e1sukat vizsg\u00e1lt\u00e1k. A 8. poliketid vegy\u00fcletnek bizonyos m\u00e9rt\u00e9k\u0171 tiszt\u00edt\u00f3 hat\u00e1sa van a DPPH, ABTS+ \u00e9s OH gy\u00f6k\u00f6kre, m\u00edg a 11. \u00e9s 12. vegy\u00fcletnek DPPH \u00e9s ABTS+ gy\u00f6k\u00f6kre van tiszt\u00edt\u00f3 hat\u00e1sa. A szabad gy\u00f6kfog\u00f3 aktivit\u00e1s azt jelzi, hogy az arom\u00e1s hidroxilcsoportok fontosak a szabad gy\u00f6kfog\u00f3 aktivit\u00e1s szempontj\u00e1b\u00f3l, de a 6., 9. \u00e9s 10. szteroid vegy\u00fcletek nem rendelkeznek DPPH-ra kifejtett gy\u00f6kfog\u00f3 hat\u00e1ssal, \u00e9s csak az OH gy\u00f6k\u00f6kre van er\u0151s gy\u00f6kfog\u00f3 hat\u00e1suk. Kor\u00e1bbi tanulm\u00e1nyok kimutatt\u00e1k, hogy a szteroid vegy\u00fcletek nem rendelkeznek DPPH-ra kifejt\u0151 hat\u00e1ssal, de az OH-gy\u00f6k\u00f6kre er\u0151s hat\u00e1ssal vannak. A poliketid vegy\u00fcletek er\u0151s aktivit\u00e1ssal rendelkeznek a DPPH ellen, \u00e9s mind a szteroid, mind a poliketid vegy\u00fcletek a f\u0151 antioxid\u00e1ns hat\u00f3anyagok az Aspergillus nigerben. A poliketid vegy\u00fcletek az\u00e9rt rendelkeznek bizonyos antioxid\u00e1ns hat\u00e1ssal, mert a poliketidek \u00e9s a flavonoidok szubsztituensek hasonl\u00f3ak. A szabadgy\u00f6k-elm\u00e9let alapj\u00e1n a fenolos hidroxilcsoportok er\u0151sen reduk\u00e1lhat\u00f3k, \u00e9s a poliketid vegy\u00fcletek t\u00f6bbnyire t\u00f6bbsz\u00f6r\u00f6s hidroxilszerkezet\u0171ek, er\u0151s antioxid\u00e1ns kapacit\u00e1ssal. Ez a tanulm\u00e1ny gazdag\u00edtja az Aspergillus fumigatus k\u00e9miai \u00f6sszet\u00e9tel\u00e9t, \u00e9s bizonyos referencia\u00e9rt\u00e9ket biztos\u00edt a j\u00f6v\u0151ben e t\u00f6rzs szil\u00e1rd ferment\u00e1ci\u00f3s termeszt\u00e9s\u00e9hez \u00e9s fejleszt\u00e9s\u00e9hez.<\/p>","protected":false},"excerpt":{"rendered":"

Chemical Composition and Antioxidant Activity of Solid Fermentation Products of Soil Fungi Aspergillus fumigatus In recent years, research on soil fungal diversity has received widespread attention. Soil contains abundant microbial resources and is one of the most complex microbial ecosystems on Earth. Due to the close connection between fungi, soil, and plant roots, they jointly […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nChemical Composition and Antioxidant Activity of Solid Fermentation Products of Soil Fungi Aspergillus fumigatus - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/talajgombak-aspergillus-fumigatus\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chemical Composition and Antioxidant Activity of Solid Fermentation Products of Soil Fungi Aspergillus fumigatus - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Chemical Composition and Antioxidant Activity of Solid Fermentation Products of Soil Fungi Aspergillus fumigatus In recent years, research on soil fungal diversity has received widespread attention. 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