{"id":8629,"date":"2024-08-14T18:33:49","date_gmt":"2024-08-14T18:33:49","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=8629"},"modified":"2024-08-14T18:33:49","modified_gmt":"2024-08-14T18:33:49","slug":"pseudomonas-ovale","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/pseudomonas-ovale\/","title":{"rendered":"A Pseudomonas Ovale, egy endofita bakt\u00e9rium metabolitjainak kutat\u00e1sa Chuanxiongban"},"content":{"rendered":"

A Pseudomonas Ovale, egy endofita bakt\u00e9rium metabolitjainak kutat\u00e1sa Chuanxiongban
\nA gazdaszervezettel val\u00f3 mutualisztikus szimbi\u00f3zis sor\u00e1n a n\u00f6v\u00e9nyek endofita bakt\u00e9riumai sz\u00e1mos farmakol\u00f3giai hat\u00e1s\u00fa anyagcsereterm\u00e9ket is termelnek. A chuanxiong a Ligusticum chuanxiong Hort. sz\u00e1r\u00edtott riz\u00f3m\u00e1ja, amely az Umbelliferae csal\u00e1dba tartoz\u00f3 n\u00f6v\u00e9ny. \u00cdze cs\u00edp\u0151s \u00e9s enyh\u00e9n keserny\u00e9s, valamint meleg jelleg\u0171. A v\u00e9rkering\u00e9st el\u0151seg\u00edt\u0151, a szelet el\u0171z\u0151 \u00e9s a f\u00e1jdalmat enyh\u00edt\u0151 hat\u00e1s\u00fa. Jelenleg sz\u00e1mos kutat\u00e1s foglalkozik a Ligusticum chuanxiong k\u00e9miai \u00f6sszet\u00e9tel\u00e9vel \u00e9s farmakol\u00f3giai aktivit\u00e1s\u00e1val, de m\u00e9g mindig viszonylag kev\u00e9s kutat\u00e1s van a Ligusticum chuanxiong endofita bakt\u00e9riumainak k\u00e9miai \u00f6sszet\u00e9tel\u00e9r\u0151l. A Ligusticum chuanxiongban k\u00fcl\u00f6nb\u00f6z\u0151 t\u00edpus\u00fa endofita gomb\u00e1k vannak, \u00e9s Wang et al. 87 endofita gomb\u00e1t izol\u00e1lt a Ligusticum chuanxiong riz\u00f3m\u00e1ib\u00f3l; A tud\u00f3sok tanulm\u00e1nyozt\u00e1k a Chuanxiongban tal\u00e1lhat\u00f3 Cladosporium sp. \u00e9s Fusarium tricintum endofita bakt\u00e9riumok metabolitjait, \u00e9s izol\u00e1ltak bel\u0151l\u00fck n\u00e9h\u00e1ny szerkezetileg \u00fajszer\u0171 \u00e9s rendk\u00edv\u00fcl akt\u00edv vegy\u00fcletet. A Pseudomonas nemzets\u00e9g 10 bakt\u00e9riumfajt tartalmaz, nevezetesen a P bakeri\u3001P. irregulare\u3001P. jaipurense\u3001P. desertorum\u3001P. luteolum\u3001P. ovale\u3001P. punctatum\u3001P. zonatum\u3001P. macroglobosum\u3001P. hygrophilum\u3002 Az 1960-as \u00e9vek v\u00e9g\u00e9t\u0151l a 21. sz\u00e1zad elej\u00e9ig n\u00e9h\u00e1ny tud\u00f3s tanulm\u00e1nyok sor\u00e1t v\u00e9gezte a Pseudomonas aeruginosa metabolitjaival kapcsolatban, \u00e9s foszfolipideket, pseurotint A-E, valamint G, X, Y \u00e9s Z sejtrelaxinokat izol\u00e1lt bel\u0151l\u00fck. A kutat\u00f3csoport a hagyom\u00e1nyos k\u00ednai orvosl\u00e1sban el\u0151fordul\u00f3 endofita bakt\u00e9riumok k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek tanulm\u00e1nyoz\u00e1s\u00e1val foglalkozott, \u00e9s a Chuanxiong Ovale gy\u00f6ker\u00e9b\u0151l sz\u00e1rmaz\u00f3 P. t\u00f6rzset kapott endofita bakt\u00e9riumokat nagy\u00fczemi ferment\u00e1ci\u00f3nak vetett\u00e9k al\u00e1 PDB k\u00f6zeggel ebben a tanulm\u00e1nyban. A m\u00e1sodlagos metabolitokat izol\u00e1lt\u00e1k, tiszt\u00edtott\u00e1k \u00e9s szerkezetileg azonos\u00edtott\u00e1k, \u00e9s gyullad\u00e1scs\u00f6kkent\u0151 aktivit\u00e1sukat kimutatt\u00e1k a farmakol\u00f3giai aktivit\u00e1ssal rendelkez\u0151 vegy\u00fcletek azonos\u00edt\u00e1sa \u00e9s a Ligusticum chuanxiong endofita bakt\u00e9riumok k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek kutat\u00e1s\u00e1nak gazdag\u00edt\u00e1sa \u00e9rdek\u00e9ben.<\/p>\n

Ebben a tanulm\u00e1nyban egy endofita P. bakt\u00e9riumot izol\u00e1ltak a Ligusticum chuanxiong ovale-b\u00f3l\uff0c Egy \u00faj poliketon vegy\u00fcletet \u00e9s n\u00e9gy ismert vegy\u00fcletet izol\u00e1ltak a kiterjesztett ferment\u00e1ci\u00f3 etil-acet\u00e1t kivonat\u00e1b\u00f3l makropor\u00f3zus gyant\u00e1val, k\u00f6zepes nyom\u00e1s\u00fa C18, k\u00f6zepes nyom\u00e1s\u00fa MCI \u00e9s g\u00e9loszlop seg\u00edts\u00e9g\u00e9vel. Mind az \u00f6t vegy\u00fcletet el\u0151sz\u00f6r izol\u00e1lt\u00e1k ebb\u0151l a bakt\u00e9riumnemzets\u00e9gb\u0151l. Ez\u00fattal P Az ov\u00e1lis ferment\u00e1ci\u00f3val elk\u00fcl\u00f6n\u00edtett anyagcsere-fajokat nagy teljes\u00edtm\u00e9ny\u0171 folyad\u00e9kkromatogr\u00e1fi\u00e1val elemezt\u00fck, ami azt mutatta, hogy a 60% ut\u00e1n a D101 makropor\u00f3zus gyanta metanolfrakci\u00f3j\u00e1ban m\u00e9g mindig sok, f\u0151k\u00e9nt homol\u00f3g vegy\u00fclet volt (Fr.3). Az el\u00e9gtelen ferment\u00e1ci\u00f3 miatt azonban nem izol\u00e1lt\u00e1k \u0151ket. Ez\u00e9rt felt\u00e9telezhet\u0151, hogy ebben a bakt\u00e9riumban m\u00e9g sok felfedezetlen k\u00e9miai komponens van, k\u00f6zt\u00fck \u00faj szerkezet\u0171 vegy\u00fcletek, amelyeket \u00e9rdemes felt\u00e1rni; Az 1. vegy\u00fclet j\u00f3 gyullad\u00e1scs\u00f6kkent\u0151 aktivit\u00e1sa miatt az irodalmi jelent\u00e9sek szerint a 2. vegy\u00fclet is er\u0151s gyullad\u00e1scs\u00f6kkent\u0151 aktivit\u00e1ssal rendelkezik. A fenti aktivit\u00e1sok mellett a 3. vegy\u00fclet m\u00e9rs\u00e9kelt antibakteri\u00e1lis aktivit\u00e1st mutat az MRSA-val szemben, 80 \u03bc g\/m MIC-\u00e9rt\u00e9kkel; A 4. vegy\u00fclet citotoxikus aktivit\u00e1st mutat a P388 \u00e9s az A-549 sejtvonalakkal szemben, \u00e9s jelent\u0151s g\u00e1tl\u00f3 hat\u00e1ssal van a m\u00e1jr\u00e1kos sejtekre (CBRH-7919), mint p\u00e9ld\u00e1ul a P Az ovale tov\u00e1bbi kutat\u00e1sa v\u00e1rhat\u00f3an tov\u00e1bbi j\u00f3 farmakol\u00f3giai aktivit\u00e1s\u00fa vegy\u00fcleteket eredm\u00e9nyez.<\/p>","protected":false},"excerpt":{"rendered":"

Research on Metabolites of Pseudomonas Ovale, an Endophytic Bacteria in Chuanxiong During the process of mutualistic symbiosis with the host, endophytic bacteria in plants also produce many metabolites with pharmacological activity. Chuanxiong is the dried rhizome of Ligusticum chuanxiong Hort., a plant in the Umbelliferae family. It has a pungent and slightly bitter taste, and […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nResearch on Metabolites of Pseudomonas Ovale, an Endophytic Bacteria in Chuanxiong - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/pseudomonas-ovale\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research on Metabolites of Pseudomonas Ovale, an Endophytic Bacteria in Chuanxiong - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Research on Metabolites of Pseudomonas Ovale, an Endophytic Bacteria in Chuanxiong During the process of mutualistic symbiosis with the host, endophytic bacteria in plants also produce many metabolites with pharmacological activity. Chuanxiong is the dried rhizome of Ligusticum chuanxiong Hort., a plant in the Umbelliferae family. It has a pungent and slightly bitter taste, and […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/longchangextracts.com\/hu\/pseudomonas-ovale\/\" \/>\n<meta property=\"og:site_name\" content=\"China Chemical Manufacturer\" \/>\n<meta property=\"article:published_time\" content=\"2024-08-14T18:33:49+00:00\" \/>\n<meta name=\"author\" content=\"longcha9\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Szerz\u0151:\" \/>\n\t<meta name=\"twitter:data1\" content=\"longcha9\" \/>\n\t<meta name=\"twitter:label2\" content=\"Becs\u00fclt olvas\u00e1si id\u0151\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 perc\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/longchangextracts.com\/pseudomonas-ovale\/\",\"url\":\"https:\/\/longchangextracts.com\/pseudomonas-ovale\/\",\"name\":\"Research on Metabolites of Pseudomonas Ovale, an Endophytic Bacteria in Chuanxiong - China Chemical Manufacturer\",\"isPartOf\":{\"@id\":\"https:\/\/longchangextracts.com\/#website\"},\"datePublished\":\"2024-08-14T18:33:49+00:00\",\"dateModified\":\"2024-08-14T18:33:49+00:00\",\"author\":{\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\"},\"breadcrumb\":{\"@id\":\"https:\/\/longchangextracts.com\/pseudomonas-ovale\/#breadcrumb\"},\"inLanguage\":\"hu\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/longchangextracts.com\/pseudomonas-ovale\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/longchangextracts.com\/pseudomonas-ovale\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/longchangextracts.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research on Metabolites of Pseudomonas Ovale, an Endophytic Bacteria in Chuanxiong\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/longchangextracts.com\/#website\",\"url\":\"https:\/\/longchangextracts.com\/\",\"name\":\"China Chemical Manufacturer\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/longchangextracts.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"hu\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\",\"name\":\"longcha9\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"hu\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"caption\":\"longcha9\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"A Pseudomonas Ovale, egy endofita bakt\u00e9rium metabolitjainak kutat\u00e1sa Chuanxiongban - K\u00edna K\u00e9miai Gy\u00e1rt\u00f3","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/longchangextracts.com\/hu\/pseudomonas-ovale\/","og_locale":"hu_HU","og_type":"article","og_title":"Research on Metabolites of Pseudomonas Ovale, an Endophytic Bacteria in Chuanxiong - China Chemical Manufacturer","og_description":"Research on Metabolites of Pseudomonas Ovale, an Endophytic Bacteria in Chuanxiong During the process of mutualistic symbiosis with the host, endophytic bacteria in plants also produce many metabolites with pharmacological activity. Chuanxiong is the dried rhizome of Ligusticum chuanxiong Hort., a plant in the Umbelliferae family. It has a pungent and slightly bitter taste, and […]","og_url":"https:\/\/longchangextracts.com\/hu\/pseudomonas-ovale\/","og_site_name":"China Chemical Manufacturer","article_published_time":"2024-08-14T18:33:49+00:00","author":"longcha9","twitter_card":"summary_large_image","twitter_misc":{"Szerz\u0151:":"longcha9","Becs\u00fclt olvas\u00e1si id\u0151":"3 perc"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/longchangextracts.com\/pseudomonas-ovale\/","url":"https:\/\/longchangextracts.com\/pseudomonas-ovale\/","name":"A Pseudomonas Ovale, egy endofita bakt\u00e9rium metabolitjainak kutat\u00e1sa Chuanxiongban - K\u00edna K\u00e9miai Gy\u00e1rt\u00f3","isPartOf":{"@id":"https:\/\/longchangextracts.com\/#website"},"datePublished":"2024-08-14T18:33:49+00:00","dateModified":"2024-08-14T18:33:49+00:00","author":{"@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869"},"breadcrumb":{"@id":"https:\/\/longchangextracts.com\/pseudomonas-ovale\/#breadcrumb"},"inLanguage":"hu","potentialAction":[{"@type":"ReadAction","target":["https:\/\/longchangextracts.com\/pseudomonas-ovale\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/longchangextracts.com\/pseudomonas-ovale\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/longchangextracts.com\/"},{"@type":"ListItem","position":2,"name":"Research on Metabolites of Pseudomonas Ovale, an Endophytic Bacteria in Chuanxiong"}]},{"@type":"WebSite","@id":"https:\/\/longchangextracts.com\/#website","url":"https:\/\/longchangextracts.com\/","name":"K\u00edna Vegyi Gy\u00e1rt\u00f3","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/longchangextracts.com\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"hu"},{"@type":"Person","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869","name":"longcha9","image":{"@type":"ImageObject","inLanguage":"hu","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","caption":"longcha9"}}]}},"_links":{"self":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/8629"}],"collection":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/comments?post=8629"}],"version-history":[{"count":1,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/8629\/revisions"}],"predecessor-version":[{"id":8630,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/8629\/revisions\/8630"}],"wp:attachment":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/media?parent=8629"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/categories?post=8629"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/tags?post=8629"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}