{"id":8551,"date":"2024-08-14T15:51:01","date_gmt":"2024-08-14T15:51:01","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=8551"},"modified":"2024-08-14T15:51:01","modified_gmt":"2024-08-14T15:51:01","slug":"uplc-qtof-ms","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/uplc-qtof-ms\/","title":{"rendered":"A k\u00fcl\u00f6nb\u00f6z\u0151 r\u00e9gi\u00f3kb\u00f3l sz\u00e1rmaz\u00f3 Dendrobium officinale k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek k\u00fcl\u00f6nbs\u00e9geinek elemz\u00e9se UPLC-QTOF-MS alapj\u00e1n"},"content":{"rendered":"<p>A k\u00fcl\u00f6nb\u00f6z\u0151 r\u00e9gi\u00f3kb\u00f3l sz\u00e1rmaz\u00f3 Dendrobium officinale k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek k\u00fcl\u00f6nbs\u00e9geinek elemz\u00e9se UPLC-QTOF-MS alapj\u00e1n<br \/>\nA Dendrobium officinale az Orchideaf\u00e9l\u00e9k (Orchidaceae) csal\u00e1dj\u00e1ba, a Dendrobium nemzets\u00e9gbe tartoz\u00f3 \u00e9vel\u0151, epifita l\u00e1gysz\u00e1r\u00fa n\u00f6v\u00e9ny. \u0150sid\u0151k \u00f3ta h\u00edres k\u00ednai gy\u00f3gyn\u00f6v\u00e9ny, \u00e9s f\u0151k\u00e9nt Anhui, Zhejiang, Hunan, Fujian, Guangxi, Sichuan, Yunnan \u00e9s m\u00e1s r\u00e9gi\u00f3kban elterjedt. A Dendrobium officinale f\u0151 mesters\u00e9ges termeszt\u00e9si ter\u00fcletei Yunnan, Zhejiang, Anhui \u00e9s Guangdong. A Dendrobium officinale sz\u00e1mos k\u00e9miai anyagot tartalmaz, k\u00f6zt\u00fck poliszacharidokat, alkaloidokat, flavonoidokat, benzilvegy\u00fcleteket, lign\u00e1nokat \u00e9s ill\u00e9kony k\u00e9miai komponenseket, amelyek rendk\u00edv\u00fcl magas gy\u00f3gy\u00e1szati \u00e9rt\u00e9kkel rendelkeznek. A hagyom\u00e1nyos k\u00ednai orvosl\u00e1s \u00fagy v\u00e9li, hogy a Dendrobium officinale t\u00e1pl\u00e1lja a gyomrot \u00e9s folyad\u00e9kot termel, t\u00e1pl\u00e1lja a jint \u00e9s tiszt\u00edtja a h\u0151t. Olyan t\u00fcnetek kezel\u00e9s\u00e9re haszn\u00e1lj\u00e1k, mint a l\u00e1z \u00e9s a folyad\u00e9kk\u00e1rosod\u00e1s, a sz\u00e1jsz\u00e1razs\u00e1g \u00e9s a szomj\u00fas\u00e1g, a gyomor el\u00e9gtelen yinje \u00e9s az el\u00e9gtelen t\u00e1pl\u00e1l\u00e9kbevitel okozta sz\u00e1raz h\u00e1ny\u00e1s. A modern farmakol\u00f3giai kutat\u00e1sok kimutatt\u00e1k, hogy a Dendrobium officinale flavonoidjai hipoglik\u00e9mi\u00e1s hat\u00e1s\u00faak, m\u00edg a benzilvegy\u00fcletek \u00e9s poliszacharidok gyullad\u00e1scs\u00f6kkent\u0151 tulajdons\u00e1gokkal b\u00edrhatnak. A benzilvegy\u00fcletek, flavonoidok \u00e9s fenolos vegy\u00fcletek antioxid\u00e1ns hat\u00e1s\u00faak, a benzilvegy\u00fcletek r\u00e1kellenes hat\u00e1s\u00faak, a poliszacharidok pedig szab\u00e1lyozhatj\u00e1k a szervezet immunrendszer\u00e9t.<br \/>\nGy\u00f3gyn\u00f6v\u00e9nyk\u00e9nt a Dendrobium officinale term\u00e9s\u00e9t \u00e9s min\u0151s\u00e9g\u00e9t olyan t\u00e9nyez\u0151k befoly\u00e1solj\u00e1k, mint az eredeti n\u00f6v\u00e9nyfaj, a term\u0151ter\u00fclet, az \u00fcltet\u00e9si technika, a talaj t\u00e1panyagtartalma, az \u00e9ghajlati viszonyok \u00e9s a betakar\u00edt\u00e1si id\u0151szak. A Dendrobium officinale vadon term\u0151 n\u00f6v\u00e9nyei ritk\u00e1k, \u00e9s a piacon jelenleg forgalomban l\u00e9v\u0151 kereskedelmi Dendrobium officinale f\u0151k\u00e9nt mesters\u00e9ges \u00fcltetv\u00e9nyekr\u0151l sz\u00e1rmazik orsz\u00e1gszerte. Az \u00fcltet\u00e9si alapok sz\u00e9les k\u00f6r\u0171 elterjed\u00e9se miatt a k\u00fcl\u00f6nb\u00f6z\u0151 r\u00e9gi\u00f3kban termesztett Dendrobium officinale n\u00f6veked\u00e9si folyamat\u00e1nak k\u00fcl\u00f6nb\u00f6z\u0151 k\u00f6r\u00fclm\u00e9nyei nem garant\u00e1lhat\u00f3k, ami elker\u00fclhetetlen\u00fcl a Dendrobium officinale gy\u00f3gy\u00e1szati \u00e9rt\u00e9k\u00e9nek elt\u00e9r\u00e9seihez vezet. A K\u00ednai Gy\u00f3gyszerk\u00f6nyv 2020-as kiad\u00e1s\u00e1ban a Dendrobium officinale min\u0151s\u00e9g\u00e9nek \u00e9rt\u00e9kel\u00e9si m\u00f3dszere szerint a min\u0151s\u00e9g \u00e9rt\u00e9kel\u00e9s\u00e9re a poliszacharidok \u00e9s az alkoholban old\u00f3d\u00f3 kivonatok tartalm\u00e1t haszn\u00e1lj\u00e1k szabv\u00e1nyk\u00e9nt. A gy\u00f3gyszerk\u00f6nyvben meghat\u00e1rozott poliszacharidok \u00e9s alkoholban old\u00f3d\u00f3 kivonatok nyers kivonatok, \u00e9s a kimutat\u00e1si m\u00f3dszerek viszonylag egyszer\u0171ek, ami k\u00f6nnyen jelent\u0151s hib\u00e1khoz vezethet. Ez azt jelzi, hogy a Dendrobium officinale min\u0151s\u00e9g\u00e9nek \u00e9rt\u00e9kel\u00e9si mutat\u00f3jak\u00e9nt kiz\u00e1r\u00f3lag a poliszacharidok \u00e9s az alkoholban old\u00f3d\u00f3 kivonatok tartalm\u00e1t haszn\u00e1lni bizonyos korl\u00e1tokkal j\u00e1r. Ez\u00e9rt a min\u0151s\u00e9gi kalibr\u00e1l\u00e1shoz felt\u00e9tlen\u00fcl ki kell v\u00e1lasztani a Dendrobium officinale magas tartalm\u00fa \u00e9s j\u00f3 farmakol\u00f3giai aktivit\u00e1s\u00fa k\u00e9miai komponens\u00e9t. E k\u00eds\u00e9rlet c\u00e9lja a k\u00fcl\u00f6nb\u00f6z\u0151 eredet\u0171 Dendrobium officinale k\u00e9miai \u00f6sszetev\u0151inek \u00e1tfog\u00f3 elemz\u00e9se, a poliszacharidok kiv\u00e9tel\u00e9vel, a Dendrobium officinale min\u0151s\u00e9g\u00e9nek \u00e9rt\u00e9kel\u00e9s\u00e9re szolg\u00e1l\u00f3 marker komponensek azonos\u00edt\u00e1sa \u00e9s a Dendrobium officinale min\u0151s\u00e9g\u00e9rt\u00e9kel\u00e9si szabv\u00e1nyainak jav\u00edt\u00e1sa \u00e9rdek\u00e9ben.<\/p>\n<p>A gy\u00f3gyn\u00f6v\u00e9nyek aktivit\u00e1s\u00e1t befoly\u00e1solja m\u00e1sodlagos anyagcsereterm\u00e9keik \u00f6sszet\u00e9tele \u00e9s tartalma: egyr\u00e9szt a gy\u00f3gyn\u00f6v\u00e9nyek fajt\u00e1i \u00e1ltal okozott g\u00e9nexpresszi\u00f3s k\u00fcl\u00f6nbs\u00e9gekt\u0151l f\u00fcgg; m\u00e1sr\u00e9szt a mez\u0151gazdas\u00e1gi \u00e9ghajlati viszonyok, mint a csapad\u00e9k, a h\u0151m\u00e9rs\u00e9klet, a p\u00e1ratartalom \u00e9s a naps\u00fct\u00e9s a n\u00f6veked\u00e9si folyamat sor\u00e1n, valamint a sz\u00e1nt\u00f3f\u00f6ldi gazd\u00e1lkod\u00e1s is jelent\u0151s hat\u00e1ssal van a min\u0151s\u00e9gre. A gy\u00f3gyn\u00f6v\u00e9nyek kutat\u00e1s\u00e1nak folyamatos elm\u00e9ly\u00fcl\u00e9s\u00e9vel a hagyom\u00e1nyos k\u00ednai gy\u00f3gy\u00e1szat min\u0151s\u00e9g\u00e9rt\u00e9kel\u00e9si rendszere, amely egyetlen k\u00e9miai komponensre mint indik\u00e1torra \u00e9p\u00fcl, bizonyos korl\u00e1tokkal rendelkezik. A Dendrobium officinale poliszacharidjai mellett a Dendrobium officinale-ban jelent\u0151s mennyis\u00e9g\u0171 kismolekul\u00e1ris k\u00e9miai komponens is jelen van. Ezeknek a k\u00e9miai \u00f6sszetev\u0151knek a sz\u00e9les k\u00f6r\u0171 elemz\u00e9se \u00e9s a Dendrobium officinale gy\u00f3gy\u00e1szati anyagok min\u0151s\u00e9g\u00e9vel val\u00f3 \u00f6sszekapcsol\u00e1sa nagy jelent\u0151s\u00e9ggel b\u00edr a n\u00f6veked\u00e9si k\u00f6rnyezet \u00e9s az \u00fcltet\u00e9si technik\u00e1k, valamint a Dendrobium officinale min\u0151s\u00e9ge k\u00f6z\u00f6tti kapcsolat azonos\u00edt\u00e1sa szempontj\u00e1b\u00f3l. Ez elengedhetetlen a Dendrobium officinale min\u0151s\u00e9g\u00e9rt\u00e9kel\u00e9si szabv\u00e1nyainak k\u00e9s\u0151bbi jav\u00edt\u00e1s\u00e1hoz.<br \/>\nEz a tanulm\u00e1ny a Dendrobium officinale k\u00fcl\u00f6nb\u00f6z\u0151 eredet\u0171 alkoholos kivonatainak term\u00e9szetes kis molekul\u00e1k \u00f6sszet\u00e9tel\u00e9t \u00e9s tartalm\u00e1t vizsg\u00e1lta UPLC-Q-TOF-MS seg\u00edts\u00e9g\u00e9vel, \u00e9s tov\u00e1bb vizsg\u00e1lta a Dendrobium officinale, egy gyakran haszn\u00e1lt hagyom\u00e1nyos k\u00ednai gy\u00f3gy\u00e1szat min\u0151s\u00e9g\u00e9rt\u00e9kel\u00e9si szabv\u00e1nyait. A Dendrobium officinale etanolos kivonat\u00e1n min\u0151s\u00e9gi elemz\u00e9st v\u00e9geztek, \u00e9s \u00f6sszesen 32 f\u0151 komponenst azonos\u00edtottak. K\u00e9miai elemz\u0151 szoftvereket \u00e9s helyi adatb\u00e1zisokat haszn\u00e1ltak a lehets\u00e9ges szerkezetek \u00e9s molekul\u00e1ris k\u00e9pletek megsejt\u00e9s\u00e9hez, amelyek eredm\u00e9nyek\u00e9nt (-) - lirioresinol B frukt\u00f3z-fenilalanin\u3001 vanilinsav, p-hidroxi-benzoesav, dendrobin \u00e9s m\u00e1s k\u00e9miai szerkezetek j\u00f6ttek l\u00e9tre. Ezek k\u00f6z\u00fcl 13 komponenst mutattak ki a Dendrobium officinale k\u00fcl\u00f6nb\u00f6z\u0151 eredet\u0171 etanolos kivonataiban, ami azt jelzi, hogy b\u00e1r a Dendrobium officinale \u00e1ltal termelt m\u00e1sodlagos metabolitok k\u00fcl\u00f6nb\u00f6z\u0151 eredet\u0171ek, f\u0151 hat\u00f3anyagaik nagyfok\u00fa hasonl\u00f3s\u00e1got mutatnak. A Dendrobium officinale gazdag fenolos vegy\u00fcletekben, els\u0151sorban a dendrobin \u00e1ltal k\u00e9pviselt benzilvegy\u00fcletekben \u00e9s a naringenin \u00e1ltal k\u00e9pviselt flavonoidokban. Ennek megfelel\u0151en a standard mint\u00e1k mennyis\u00e9gi elemz\u00e9se azt mutatta, hogy a dendrobin \u00e9s a naringin tartalma elt\u00e9r a k\u00fcl\u00f6nb\u00f6z\u0151 eredet\u0171 Dendrobium officinale-ban, ami azt jelzi, hogy ez a k\u00e9t vegy\u00fclet a Dendrobium officinale potenci\u00e1lis min\u0151s\u00e9g\u00e9rt\u00e9kel\u00e9si mutat\u00f3jak\u00e9nt szolg\u00e1lhat.<br \/>\nAz elm\u00falt \u00e9vekben kutat\u00f3csoportunk a Dendrobium officinale \u00faj \u00f6sszetev\u0151inek \u00e9s funkci\u00f3inak fejleszt\u00e9s\u00e9re \u00f6sszpontos\u00edtott, k\u00fcl\u00f6n\u00f6sen a kozmetikumok ter\u00fclet\u00e9n t\u00f6rt\u00e9n\u0151 alkalmaz\u00e1s\u00e1ra. Chen \u00e9s Qi tanulm\u00e1nyt v\u00e9gzett a Dendrobium officinale poliszacharidok hidrat\u00e1l\u00f3 tulajdons\u00e1gair\u00f3l, \u00e9s az eredm\u00e9nyek azt mutatt\u00e1k, hogy a Dendrobium officinale poliszacharid kivonatok j\u00f3 hidrat\u00e1l\u00f3 hat\u00e1ssal rendelkeznek, \u00e9s k\u00e9pesek jav\u00edtani a b\u0151rsejtek toleranci\u00e1j\u00e1t a sz\u00e1raz k\u00f6rnyezetben. A poliszacharidok mellett a Dendrobium officinale nagy mennyis\u00e9g\u0171 fenolos vegy\u00fcletet is tartalmaz, amelyek term\u00e9szetes antioxid\u00e1nsok, amelyek bizonyos DPPH \u00e9s ABTS szabadgy\u00f6k-elt\u00e1vol\u00edt\u00f3 aktivit\u00e1st mutatnak in vitro k\u00eds\u00e9rletekben. Jelenleg a Dendrobium officinale-t, mint cs\u00facskateg\u00f3ri\u00e1s kozmetikai \u00f6sszetev\u0151t, sz\u00e9les k\u00f6rben haszn\u00e1lj\u00e1k a sz\u00e9ps\u00e9g- \u00e9s b\u0151r\u00e1pol\u00e1si term\u00e9kekben, \u00e9s a fogyaszt\u00f3k kedvelik.<br \/>\nA Dendrobium officinale alkoholos kivonat\u00e1ban l\u00e9v\u0151 lehets\u00e9ges hat\u00f3anyagok tiszt\u00e1z\u00e1sa \u00e9s a b\u0151r\u00e1pol\u00f3 term\u00e9kek fejleszt\u00e9s\u00e9ben val\u00f3 jobb felhaszn\u00e1l\u00e1sa \u00e9rdek\u00e9ben k\u00e9miai \u00f6sszet\u00e9tel-elemz\u00e9st v\u00e9gezt\u00fcnk a Dendrobium officinale k\u00fcl\u00f6nb\u00f6z\u0151 eredet\u0171 alkoholos kivonatain, elm\u00e9leti alapot ny\u00fajtva a Dendrobium officinale tudom\u00e1nyos \u00e9s \u00e9sszer\u0171 felhaszn\u00e1l\u00e1s\u00e1hoz.<\/p>","protected":false},"excerpt":{"rendered":"<p>Analysis of Chemical Composition Differences in Dendrobium officinale from Different Regions Based on UPLC-QTOF-MS Dendrobium officinale is a perennial epiphytic herbaceous plant in the Orchidaceae family, belonging to the Dendrobium genus. It has been a famous Chinese medicinal herb since ancient times and is mainly distributed in Anhui, Zhejiang, Hunan, Fujian, Guangxi, Sichuan, Yunnan and [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Analysis of Chemical Composition Differences in Dendrobium officinale from Different Regions Based on UPLC-QTOF-MS - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/uplc-qtof-ms\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Analysis of Chemical Composition Differences in Dendrobium officinale from Different Regions Based on UPLC-QTOF-MS - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Analysis of Chemical Composition Differences in Dendrobium officinale from Different Regions Based on UPLC-QTOF-MS Dendrobium officinale is a perennial epiphytic herbaceous plant in the Orchidaceae family, belonging to the Dendrobium genus. 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