{"id":8189,"date":"2024-08-11T20:07:58","date_gmt":"2024-08-11T20:07:58","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=8189"},"modified":"2024-08-11T20:08:12","modified_gmt":"2024-08-11T20:08:12","slug":"chloroform-and-n-butanol","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/chloroform-and-n-butanol\/","title":{"rendered":"A kloroform \u00e9s az n-butanol r\u00e9szek k\u00e9miai \u00f6sszetev\u0151inek vizsg\u00e1lata sz\u00e9les izomzat\u00fa sz\u0151l\u0151ben"},"content":{"rendered":"<p>A kloroform \u00e9s az n-butanol r\u00e9szek k\u00e9miai \u00f6sszetev\u0151inek vizsg\u00e1lata sz\u00e9les izomzat\u00fa sz\u0151l\u0151ben<br \/>\nA Kuanjinteng a Menispermaceae csal\u00e1dba tartoz\u00f3 Tinosporae sinenisis (Lour.) Merr. sz\u00e1r\u00edtott sz\u0151l\u0151sz\u00e1ra. Els\u0151sorban Guangdong, Guangxi, Yunnan \u00e9s m\u00e1s r\u00e9gi\u00f3kban elterjedt, sz\u00e9les k\u00f6rben elterjedt, nagy term\u00e9shozam\u00fa, \u00e9s r\u00e9g\u00f3ta alkalmazz\u00e1k a n\u00e9pi kult\u00far\u00e1ban. A K\u00ednai Gy\u00f3gyn\u00f6v\u00e9nyes Gy\u00f3gyszerek Nemzeti Kompendiuma szerint a Kuan Jin Teng enyh\u00e9n keserny\u00e9s \u00edz\u0171 \u00e9s h\u0171v\u00f6s term\u00e9szet\u0171, \u00e9s a szelet el\u0171z\u0151, f\u00e1jdalmat enyh\u00edt\u0151, izmokat ellaz\u00edt\u00f3 \u00e9s kollater\u00e1lisokat aktiv\u00e1l\u00f3 hat\u00e1s\u00fa. A tibeti gy\u00f3gy\u00e1szatban \"Lezhe\" n\u00e9ven is ismert Kuanjinteng a tibeti gy\u00f3gy\u00e1szatban gyakran haszn\u00e1lt gy\u00f3gyn\u00f6v\u00e9ny. J\u00f3l eloszlatja a szelet \u00e9s a nedvess\u00e9get, ellaz\u00edtja az inakat \u00e9s aktiv\u00e1lja a kollater\u00e1lisokat, \u00e9s jelent\u0151s ter\u00e1pi\u00e1s hat\u00e1ssal rendelkezik. A \"Jingzhu Bencao\" feljegyzi, hogy a Kuanjinteng \"kezeli a hasmen\u00e9s \u00e9s a v\u00f6r\u00f6s v\u00e9r pang\u00e1s\u00e1nak kombin\u00e1ci\u00f3j\u00e1t, valamint a szalonn\u00e1s betegs\u00e9get, a reum\u00e1t \u00e9s a hasmen\u00e9st. A klinikai gyakorlatban a Kuan Jin Tenget els\u0151sorban ortop\u00e9diai betegs\u00e9gek, p\u00e9ld\u00e1ul reumatoid artritisz, \u00e1gy\u00e9ki izomh\u00faz\u00f3d\u00e1s \u00e9s traum\u00e1s s\u00e9r\u00fcl\u00e9sek kezel\u00e9s\u00e9re haszn\u00e1lj\u00e1k, ami nagy kutat\u00e1si \u00e9rt\u00e9k\u00e9t \u00e9s fejleszt\u00e9si potenci\u00e1lj\u00e1t jelzi. A modern farmakol\u00f3giai kutat\u00e1sok kimutatt\u00e1k, hogy az epeh\u00f3lyag nemzets\u00e9ghez tartoz\u00f3 n\u00f6v\u00e9nyek k\u00fcl\u00f6nb\u00f6z\u0151 farmakol\u00f3giai tev\u00e9kenys\u00e9gekkel rendelkeznek, p\u00e9ld\u00e1ul gyullad\u00e1scs\u00f6kkent\u0151, sug\u00e1rz\u00e1sg\u00e1tl\u00f3, daganatellenes, v\u00edrusellenes \u00e9s immunszuppressz\u00edv hat\u00e1ssal. A nemzets\u00e9g k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek jelenlegi kutat\u00e1sa azonban els\u0151sorban k\u00e9t fajra \u00f6sszpontos\u00edt: Hainan epeh\u00f3lyag \u00e9s Heart Leaf epeh\u00f3lyag. A Kuan Jin Teng, mint az epeh\u00f3lyag nemzets\u00e9gbe tartoz\u00f3 k\u00ednai z\u00f6ld teh\u00e9ng\u00e9ge n\u00f6v\u00e9ny sz\u0151l\u0151sz\u00e1r\u00e1nak, hossz\u00fa n\u00e9pi alkalmaz\u00e1si t\u00f6rt\u00e9nete \u00e9s megb\u00edzhat\u00f3 ter\u00e1pi\u00e1s hat\u00e1sai vannak. A Kuan Jin Teng jelenlegi fejleszt\u00e9se \u00e9s felhaszn\u00e1l\u00e1sa azonban m\u00e9g mindig viszonylag alacsony, \u00e9s a hazai \u00e9s k\u00fclf\u00f6ldi tud\u00f3sok farmakol\u00f3giai anyagalapj\u00e1nak kutat\u00e1sa m\u00e9g mindig viszonylag gyenge, f\u0151k\u00e9nt az etil-acet\u00e1t r\u00e9sz k\u00e9miai \u00f6sszetev\u0151inek elv\u00e1laszt\u00e1s\u00e1ra \u00f6sszpontos\u00edtva. A farmakol\u00f3giai kutat\u00e1sok t\u00f6bbnyire a Kuan Jin Teng f\u0151zet\u00e9re vagy kivonat\u00e1ra \u00f6sszpontos\u00edtanak, \u00e9s farmakol\u00f3giai anyag\u00e1nak alapjait nem siker\u00fclt teljes m\u00e9rt\u00e9kben felt\u00e1rni. A Platycodon grandiflorus k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek tov\u00e1bbi gazdag\u00edt\u00e1sa \u00e9rdek\u00e9ben ebben a k\u00eds\u00e9rletben k\u00fcl\u00f6nb\u00f6z\u0151 kromatogr\u00e1fi\u00e1s elv\u00e1laszt\u00e1si technik\u00e1kat alkalmaztak a Platycodon grandiflorus kloroformos \u00e9s n-butanolos extrakci\u00f3s r\u00e9szeinek k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek vizsg\u00e1lat\u00e1ra. Az izol\u00e1lt vegy\u00fcleteket a RAW264.7 sejtekben a lipopoliszacharid \u00e1ltal induk\u00e1lt NO-felszabadul\u00e1si aktivit\u00e1s g\u00e1tl\u00e1s\u00e1ra is tesztelt\u00fck, annak \u00e9rdek\u00e9ben, hogy a Platycodon grandiflorusb\u00f3l hat\u00f3anyagokat keress\u00fcnk \u00e9s fedezz\u00fcnk fel, \u00e9s megalapozzuk a tov\u00e1bbi fejleszt\u00e9st \u00e9s felhaszn\u00e1l\u00e1st.<\/p>\n<p>&nbsp;<\/p>\n<p>Ebben a k\u00eds\u00e9rletben t\u00f6bbf\u00e9le elv\u00e1laszt\u00e1si technik\u00e1t alkalmaztak 13 vegy\u00fclet izol\u00e1l\u00e1s\u00e1ra \u00e9s azonos\u00edt\u00e1s\u00e1ra a sz\u00e9leslevel\u0171 sz\u0151l\u0151 kloroformos \u00e9s n-butanolos r\u00e9szeib\u0151l, k\u00f6zt\u00fck 2 agyglikozid lipidvegy\u00fclet (1, 3), 5 fenilpropanoid vegy\u00fclet (5, 7, 10, 11, 12), 2 terpenoid vegy\u00fclet (4, 9), 1 aminosav vegy\u00fclet (13) \u00e9s 3 egy\u00e9b vegy\u00fclet (2, 6, 8). K\u00f6z\u00fcl\u00fck a 8. vegy\u00fcletet el\u0151sz\u00f6r jelentett\u00e9k term\u00e9szetes term\u00e9kk\u00e9nt, az 1., 2., 3., 6. \u00e9s 11. vegy\u00fcletet el\u0151sz\u00f6r izol\u00e1lt\u00e1k a Menispermaceae csal\u00e1dba tartoz\u00f3 n\u00f6v\u00e9nyekb\u0151l, a 13. vegy\u00fcletet pedig el\u0151sz\u00f6r izol\u00e1lt\u00e1k a Platycodon grandiflorusb\u00f3l. Kutat\u00e1si jelent\u00e9sek szerint a 4. vegy\u00fclet bizonyos g\u00e1tl\u00f3 hat\u00e1st fejt ki a hum\u00e1n or\u00e1lis epidermoid karcin\u00f3ma KB sejtekre \u00e9s a m\u00e9hnyak laph\u00e1msejtes karcin\u00f3ma SiHa sejtekre; a 3. vegy\u00fclet enyh\u00edtheti a szinovi\u00e1lis gyullad\u00e1st \u00e9s megel\u0151zheti az \u00edz\u00fcleti s\u00e9r\u00fcl\u00e9seket az MCP-1 expresszi\u00f3j\u00e1nak cs\u00f6kkent\u00e9se \u00e9s a monocita\/makrof\u00e1gok szinovi\u00e1lis sejtekbe val\u00f3 besziv\u00e1rg\u00e1s\u00e1nak g\u00e1tl\u00e1sa r\u00e9v\u00e9n. A k\u00e9miai \u00f6sszet\u00e9tel vizsg\u00e1lata alapj\u00e1n ez a cikk LPS induk\u00e1lt RAW264.7 sejteket haszn\u00e1lt in vitro gyullad\u00e1sos modellk\u00e9nt 13 izol\u00e1lt vegy\u00fclet gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1s\u00e1nak \u00e9rt\u00e9kel\u00e9s\u00e9re. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy a 2., 3. \u00e9s 4. vegy\u00fclet bizonyos gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1ssal rendelkezett az NO-termel\u0151d\u00e9si k\u00eds\u00e9rletek g\u00e1tl\u00e1sa r\u00e9v\u00e9n. Ez a tanulm\u00e1ny nemcsak a Platycodon grandiflorus k\u00e9miai szerkezeti t\u00edpusait \u00e9s k\u00e9miai \u00f6sszet\u00e9tel\u00e9t gazdag\u00edtja, hanem tudom\u00e1nyos alapot ny\u00fajt a farmakol\u00f3giai anyagalap tov\u00e1bbi tiszt\u00e1z\u00e1s\u00e1hoz \u00e9s a Platycodon grandiflorus er\u0151forr\u00e1s-fejleszt\u00e9s\u00e9nek el\u0151mozd\u00edt\u00e1s\u00e1hoz.<\/p>","protected":false},"excerpt":{"rendered":"<p>Study on the Chemical Components of Chloroform and n-Butanol Parts in Wide Muscle Vine Kuanjinteng is a dried vine stem of Tinosporae sinenisis (Lour.) Merr., a plant belonging to the family Menispermaceae. It is mainly distributed in Guangdong, Guangxi, Yunnan, and other regions, with a wide distribution and high yield, and has a long history [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Study on the Chemical Components of Chloroform and n-Butanol Parts in Wide Muscle Vine - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/chloroform-and-n-butanol\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study on the Chemical Components of Chloroform and n-Butanol Parts in Wide Muscle Vine - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Study on the Chemical Components of Chloroform and n-Butanol Parts in Wide Muscle Vine Kuanjinteng is a dried vine stem of Tinosporae sinenisis (Lour.) 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Merr., a plant belonging to the family Menispermaceae. It is mainly distributed in Guangdong, Guangxi, Yunnan, and other regions, with a wide distribution and high yield, and has a long history [&hellip;]","og_url":"https:\/\/longchangextracts.com\/hu\/chloroform-and-n-butanol\/","og_site_name":"China Chemical Manufacturer","article_published_time":"2024-08-11T20:07:58+00:00","article_modified_time":"2024-08-11T20:08:12+00:00","author":"longcha9","twitter_card":"summary_large_image","twitter_misc":{"Szerz\u0151:":"longcha9","Becs\u00fclt olvas\u00e1si id\u0151":"3 perc"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/longchangextracts.com\/chloroform-and-n-butanol\/","url":"https:\/\/longchangextracts.com\/chloroform-and-n-butanol\/","name":"Tanulm\u00e1ny a kloroform \u00e9s az n-butanol r\u00e9szek k\u00e9miai \u00f6sszetev\u0151inek sz\u00e9les izom sz\u0151l\u0151 - K\u00edna Chemical Manufacturer","isPartOf":{"@id":"https:\/\/longchangextracts.com\/#website"},"datePublished":"2024-08-11T20:07:58+00:00","dateModified":"2024-08-11T20:08:12+00:00","author":{"@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869"},"breadcrumb":{"@id":"https:\/\/longchangextracts.com\/chloroform-and-n-butanol\/#breadcrumb"},"inLanguage":"hu","potentialAction":[{"@type":"ReadAction","target":["https:\/\/longchangextracts.com\/chloroform-and-n-butanol\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/longchangextracts.com\/chloroform-and-n-butanol\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/longchangextracts.com\/"},{"@type":"ListItem","position":2,"name":"Study on the Chemical Components of Chloroform and n-Butanol Parts in Wide Muscle Vine"}]},{"@type":"WebSite","@id":"https:\/\/longchangextracts.com\/#website","url":"https:\/\/longchangextracts.com\/","name":"K\u00edna Vegyi Gy\u00e1rt\u00f3","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/longchangextracts.com\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"hu"},{"@type":"Person","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869","name":"longcha9","image":{"@type":"ImageObject","inLanguage":"hu","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","caption":"longcha9"}}]}},"_links":{"self":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/8189"}],"collection":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/comments?post=8189"}],"version-history":[{"count":1,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/8189\/revisions"}],"predecessor-version":[{"id":8190,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/8189\/revisions\/8190"}],"wp:attachment":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/media?parent=8189"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/categories?post=8189"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/tags?post=8189"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}