{"id":8037,"date":"2024-08-11T17:58:10","date_gmt":"2024-08-11T17:58:10","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=8037"},"modified":"2024-08-11T17:58:10","modified_gmt":"2024-08-11T17:58:10","slug":"fenfangji-root","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/fenfangji-root\/","title":{"rendered":"A Fenfangji gy\u00f6k\u00e9r k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek \u00e9s a m\u00e1jfibr\u00f3zis elleni aktivit\u00e1s\u00e1nak vizsg\u00e1lata"},"content":{"rendered":"<p>A Fenfangji gy\u00f6k\u00e9r k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek \u00e9s a m\u00e1jfibr\u00f3zis elleni aktivit\u00e1s\u00e1nak vizsg\u00e1lata<br \/>\nA Stephania tetrandra S. Moore a Menispermaceae csal\u00e1dba tartoz\u00f3 n\u00f6v\u00e9nyfaj, amely f\u0151k\u00e9nt Jiangxi, Anhui d\u00e9li r\u00e9sz\u00e9n, Zhejiangban, Fujianban \u00e9s m\u00e1s r\u00e9gi\u00f3kban elterjedt. Sz\u00e1raz gy\u00f6kereit gy\u00f3gyszerk\u00e9nt haszn\u00e1lva a szelek eloszlat\u00e1s\u00e1ra, a f\u00e1jdalom enyh\u00edt\u00e9s\u00e9re, a vizelethajt\u00e1s el\u0151seg\u00edt\u00e9s\u00e9re \u00e9s a duzzanat cs\u00f6kkent\u00e9s\u00e9re k\u00e9pes. Reuma, reuma, l\u00e1bgomba, vizel\u00e9si neh\u00e9zs\u00e9g \u00e9s ekc\u00e9ma kezel\u00e9s\u00e9re haszn\u00e1lj\u00e1k. Kor\u00e1bbi tanulm\u00e1nyok kimutatt\u00e1k, hogy a Fenfangji els\u0151sorban alkaloidokat tartalmaz, k\u00f6zt\u00fck k\u00fcl\u00f6nb\u00f6z\u0151 szerkezeti t\u00edpusokat, mint p\u00e9ld\u00e1ul bisbenzilizokinolin, protoberberin, aporfin, protoaporfin \u00e9s fenantr\u00e9n. A modern farmakol\u00f3giai kutat\u00e1sok kimutatt\u00e1k, hogy a Fen Fang Ji \u00e9s a Fen Fang Ji alkali jelent\u0151s biol\u00f3giai aktivit\u00e1ssal rendelkezik a daganatellenes, gyullad\u00e1scs\u00f6kkent\u0151 \u00e9s f\u00e1jdalomcsillap\u00edt\u00f3, m\u00e1jfibr\u00f3zis elleni, sz\u00edv- \u00e9s \u00e9rrendszeri v\u00e9delem, antibakteri\u00e1lis \u00e9s v\u00e9rnyom\u00e1scs\u00f6kkent\u0151 szempontb\u00f3l. A Fenfangji egy\u00e9b hat\u00f3anyagainak tov\u00e1bbi vizsg\u00e1lata \u00e9rdek\u00e9ben ez a tanulm\u00e1ny szisztematikusan tanulm\u00e1nyozta a Fenfangji gy\u00f6k\u00e9r k\u00e9miai \u00f6sszet\u00e9tel\u00e9t, \u00e9s felt\u00e1rta a kapott vegy\u00fcletek hat\u00e1s\u00e1t a TGF - \u03b2 1-induk\u00e1lt TGF - \u03b2 1-induk\u00e1lt LX-2 m\u00e1j csillagsejtek prolifer\u00e1ci\u00f3j\u00e1ra. A kutat\u00e1si eredm\u00e9nyek megvil\u00e1g\u00edtj\u00e1k a Fenfangji farmakol\u00f3giai hat\u00f3anyagait a m\u00e1jfibr\u00f3zis ellen, \u00e9s referenci\u00e1t ny\u00fajtanak a fibrotikus gy\u00f3gyszerek kifejleszt\u00e9s\u00e9hez.<\/p>\n<p>&nbsp;<\/p>\n<p>Ebben a tanulm\u00e1nyban 13 vegy\u00fcletet izol\u00e1ltak \u00e9s azonos\u00edtottak a Fenfangji-b\u0151l, k\u00f6zt\u00fck 7 alkaloidot, amelyek szerkezeti t\u00edpusai a berberin (1), benzil-izokinolin (2), izokinolin (4-6), pirrol (3) \u00e9s piridin (7). Az 1-13 vegy\u00fcleteket el\u0151sz\u00f6r ebb\u0151l a n\u00f6v\u00e9nyb\u0151l izol\u00e1lt\u00e1k, a 3, 4, 6-9 vegy\u00fcletekr\u0151l pedig m\u00e9g nem sz\u00e1moltak be a Gentiana nemzets\u00e9gben. Kor\u00e1bbi kutat\u00e1sok meg\u00e1llap\u00edtott\u00e1k, hogy a Fenfangji \u00f6sszetev\u0151i jelent\u0151s m\u00e1jfibr\u00f3zis-ellenes hat\u00e1ssal rendelkeznek, \u00e9s az izol\u00e1lt vegy\u00fcletek m\u00e1jfibr\u00f3zis-ellenes hat\u00e1s\u00e1t \u00e9rt\u00e9kelt\u00e9k. A vegy\u00fcletek TGF - \u03b2 1-induk\u00e1lt LX-2 sejtprolifer\u00e1ci\u00f3ra gyakorolt hat\u00e1s\u00e1nak kimutat\u00e1s\u00e1val el\u0151zetesen meghat\u00e1rozt\u00e1k a vegy\u00fcletek m\u00e1jfibr\u00f3zis-ellenes aktivit\u00e1s\u00e1t. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy hat vegy\u00fclet (2, 5, 6, 10-12) jelent\u0151s g\u00e1tl\u00f3 hat\u00e1ssal volt az LX-2 sejtek prolifer\u00e1ci\u00f3j\u00e1ra. E vizsg\u00e1lat eredm\u00e9nyei tov\u00e1bb tiszt\u00e1zz\u00e1k a Fenfangji farmakol\u00f3giai anyagainak a m\u00e1jfibr\u00f3zis elleni hat\u00e1s\u00e1ban, \u00e9s referenci\u00e1t ny\u00fajtanak a vezet\u0151 vegy\u00fcletek sz\u0171r\u00e9s\u00e9hez a m\u00e1jfibr\u00f3zis elleni hat\u00e1sban.<\/p>","protected":false},"excerpt":{"rendered":"<p>Study on the Chemical Composition and Anti Liver Fibrosis Activity of Fenfangji Root Stephania tetrandra S. Moore is a plant species in the family Menispermaceae, mainly distributed in Jiangxi, southern Anhui, Zhejiang, Fujian and other regions. Using its dry roots as medicine, it has the effects of dispelling wind, relieving pain, promoting diuresis, and reducing [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Study on the Chemical Composition and Anti Liver Fibrosis Activity of Fenfangji Root - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/fenfangji-root\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study on the Chemical Composition and Anti Liver Fibrosis Activity of Fenfangji Root - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Study on the Chemical Composition and Anti Liver Fibrosis Activity of Fenfangji Root Stephania tetrandra S. Moore is a plant species in the family Menispermaceae, mainly distributed in Jiangxi, southern Anhui, Zhejiang, Fujian and other regions. Using its dry roots as medicine, it has the effects of dispelling wind, relieving pain, promoting diuresis, and reducing [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/longchangextracts.com\/hu\/fenfangji-root\/\" \/>\n<meta property=\"og:site_name\" content=\"China Chemical Manufacturer\" \/>\n<meta property=\"article:published_time\" content=\"2024-08-11T17:58:10+00:00\" \/>\n<meta name=\"author\" content=\"longcha9\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Szerz\u0151:\" \/>\n\t<meta name=\"twitter:data1\" content=\"longcha9\" \/>\n\t<meta name=\"twitter:label2\" content=\"Becs\u00fclt olvas\u00e1si id\u0151\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 perc\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/longchangextracts.com\/fenfangji-root\/\",\"url\":\"https:\/\/longchangextracts.com\/fenfangji-root\/\",\"name\":\"Study on the Chemical Composition and Anti Liver Fibrosis Activity of Fenfangji Root - China Chemical Manufacturer\",\"isPartOf\":{\"@id\":\"https:\/\/longchangextracts.com\/#website\"},\"datePublished\":\"2024-08-11T17:58:10+00:00\",\"dateModified\":\"2024-08-11T17:58:10+00:00\",\"author\":{\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\"},\"breadcrumb\":{\"@id\":\"https:\/\/longchangextracts.com\/fenfangji-root\/#breadcrumb\"},\"inLanguage\":\"hu\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/longchangextracts.com\/fenfangji-root\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/longchangextracts.com\/fenfangji-root\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/longchangextracts.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Study on the Chemical Composition and Anti Liver Fibrosis Activity of Fenfangji Root\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/longchangextracts.com\/#website\",\"url\":\"https:\/\/longchangextracts.com\/\",\"name\":\"China Chemical Manufacturer\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/longchangextracts.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"hu\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\",\"name\":\"longcha9\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"hu\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"caption\":\"longcha9\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Tanulm\u00e1ny a k\u00e9miai \u00f6sszet\u00e9tele \u00e9s Anti m\u00e1j fibr\u00f3zis aktivit\u00e1sa Fenfangji Root - K\u00edna Chemical Manufacturer","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/longchangextracts.com\/hu\/fenfangji-root\/","og_locale":"hu_HU","og_type":"article","og_title":"Study on the Chemical Composition and Anti Liver Fibrosis Activity of Fenfangji Root - China Chemical Manufacturer","og_description":"Study on the Chemical Composition and Anti Liver Fibrosis Activity of Fenfangji Root Stephania tetrandra S. Moore is a plant species in the family Menispermaceae, mainly distributed in Jiangxi, southern Anhui, Zhejiang, Fujian and other regions. Using its dry roots as medicine, it has the effects of dispelling wind, relieving pain, promoting diuresis, and reducing [&hellip;]","og_url":"https:\/\/longchangextracts.com\/hu\/fenfangji-root\/","og_site_name":"China Chemical Manufacturer","article_published_time":"2024-08-11T17:58:10+00:00","author":"longcha9","twitter_card":"summary_large_image","twitter_misc":{"Szerz\u0151:":"longcha9","Becs\u00fclt olvas\u00e1si id\u0151":"2 perc"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/longchangextracts.com\/fenfangji-root\/","url":"https:\/\/longchangextracts.com\/fenfangji-root\/","name":"Tanulm\u00e1ny a k\u00e9miai \u00f6sszet\u00e9tele \u00e9s Anti m\u00e1j fibr\u00f3zis aktivit\u00e1sa Fenfangji Root - K\u00edna Chemical Manufacturer","isPartOf":{"@id":"https:\/\/longchangextracts.com\/#website"},"datePublished":"2024-08-11T17:58:10+00:00","dateModified":"2024-08-11T17:58:10+00:00","author":{"@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869"},"breadcrumb":{"@id":"https:\/\/longchangextracts.com\/fenfangji-root\/#breadcrumb"},"inLanguage":"hu","potentialAction":[{"@type":"ReadAction","target":["https:\/\/longchangextracts.com\/fenfangji-root\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/longchangextracts.com\/fenfangji-root\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/longchangextracts.com\/"},{"@type":"ListItem","position":2,"name":"Study on the Chemical Composition and Anti Liver Fibrosis Activity of Fenfangji Root"}]},{"@type":"WebSite","@id":"https:\/\/longchangextracts.com\/#website","url":"https:\/\/longchangextracts.com\/","name":"K\u00edna Vegyi Gy\u00e1rt\u00f3","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/longchangextracts.com\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"hu"},{"@type":"Person","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869","name":"longcha9","image":{"@type":"ImageObject","inLanguage":"hu","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","caption":"longcha9"}}]}},"_links":{"self":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/8037"}],"collection":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/comments?post=8037"}],"version-history":[{"count":1,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/8037\/revisions"}],"predecessor-version":[{"id":8038,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/8037\/revisions\/8038"}],"wp:attachment":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/media?parent=8037"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/categories?post=8037"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/tags?post=8037"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}