{"id":7903,"date":"2024-08-11T09:42:58","date_gmt":"2024-08-11T09:42:58","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=7903"},"modified":"2024-08-11T09:42:58","modified_gmt":"2024-08-11T09:42:58","slug":"artemisia-annua","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/artemisia-annua\/","title":{"rendered":"Az Artemisia annua \u00f6sszes flavonoidj\u00e1nak extrakci\u00f3ja, tiszt\u00edt\u00e1sa \u00e9s antioxid\u00e1ns aktivit\u00e1s\u00e1nak vizsg\u00e1lata"},"content":{"rendered":"<p>Az Artemisia annua \u00f6sszes flavonoidj\u00e1nak extrakci\u00f3ja, tiszt\u00edt\u00e1sa \u00e9s antioxid\u00e1ns aktivit\u00e1s\u00e1nak vizsg\u00e1lata<br \/>\nAz Artemisia japonica Thunb. az Asteraceae csal\u00e1dba tartoz\u00f3 Artemisia faj, amely K\u00edna sz\u00e1mos r\u00e9sz\u00e9n elterjedt. Illatos illat\u00fa, \u00e9vel\u0151 gy\u00f3gyn\u00f6v\u00e9ny, amely gy\u00f3gy- \u00e9s ehet\u0151 n\u00f6v\u00e9ny. Zsenge sz\u00e1ra \u00e9s levelei ehet\u0151ek \u00e9s kiv\u00e1l\u00f3 \u00edz\u0171ek. Az Artemisia annua keserny\u00e9s \u00e9s enyh\u00e9n \u00e9des \u00edz\u0171, h\u0171v\u00f6s jelleg\u0171, \u00e9s eg\u00e9sz gy\u00f3gyn\u00f6v\u00e9nyk\u00e9nt gy\u00f3gy\u00e1szati c\u00e9lokra haszn\u00e1lhat\u00f3; H\u0151tiszt\u00edt\u00f3, v\u00e9rh\u0171t\u0151 \u00e9s m\u00e9regtelen\u00edt\u0151 hat\u00e1s\u00fa. A modern farmakol\u00f3giai kutat\u00e1sok kimutatt\u00e1k, hogy az Artemisia annua b\u0151s\u00e9ges vegy\u00fcleteket tartalmaz, mint p\u00e9ld\u00e1ul flavonoidokat, poliszacharidokat, polifenolokat, szaponinokat \u00e9s ill\u00f3olajokat, amelyeknek k\u00fcl\u00f6nb\u00f6z\u0151 eg\u00e9szs\u00e9g\u00fcgyi el\u0151nyei vannak, p\u00e9ld\u00e1ul gyullad\u00e1scs\u00f6kkent\u0151, antioxid\u00e1ns \u00e9s \u00f6reged\u00e9sg\u00e1tl\u00f3 hat\u00e1suk. Az Artemisia annua-ban tal\u00e1lhat\u00f3 terp\u00e9nek, alkaloidok, flavonoidok, szteroidok, fenolok, egyedi aminosavak \u00e9s poliszacharidok rovar\u00f6l\u0151, antibakteri\u00e1lis \u00e9s baktericid hat\u00e1ssal rendelkeznek, \u00e9s felhaszn\u00e1lhat\u00f3k n\u00f6v\u00e9nyi alap\u00fa rovar\u00f6l\u0151 szerek kifejleszt\u00e9s\u00e9re.<\/p>\n<p>A flavonoidok a karbonilcsoportokkal rendelkez\u0151 term\u00e9szetes szerves term\u00e9kek egy oszt\u00e1lya, \u00e9s az\u00e9rt nevezik \u0151ket flavonoidoknak, mert t\u00f6bbnyire sz\u00ednesek. A n\u00f6v\u00e9nyekben tal\u00e1lhat\u00f3 m\u00e1sodlagos metabolitok fontos oszt\u00e1lyak\u00e9nt a flavonoidok jelent\u0151s \u00e9lettani \u00e9s farmakol\u00f3giai hat\u00e1sokkal rendelkeznek. A term\u00e9szetben a k\u00e9tszik\u0171 n\u00f6v\u00e9nyek, p\u00e9ld\u00e1ul az Asteraceae, Leguminosae \u00e9s Lamiaceae \u00e1ltal\u00e1ban t\u00f6bb flavonoidot tartalmaznak. Az Asteraceae csal\u00e1dba tartoz\u00f3 Artemisia nemzets\u00e9g egyik n\u00f6v\u00e9nye, az Artemisia annua k\u00fcl\u00f6n\u00f6sen gazdag flavonoidokban.<\/p>\n<p>Jelenleg az Artemisia annua-t sz\u00e9les k\u00f6rben haszn\u00e1lj\u00e1k fogyaszt\u00e1sra sz\u00e1nt z\u00f6lds\u00e9gk\u00e9nt vagy gy\u00f3gyn\u00f6v\u00e9nyk\u00e9nt a hagyom\u00e1nyos k\u00ednai orvosl\u00e1s klinikai formul\u00e1iban. Az Artemisia annua gy\u00f3gy\u00e1szati er\u0151forr\u00e1sainak fejleszt\u00e9se a modern orvostudom\u00e1nyban \u00e9s az eg\u00e9szs\u00e9g\u00fcgyben m\u00e9g mindig alacsony szinten van, \u00e9s kev\u00e9s kutat\u00e1si jelent\u00e9s l\u00e9tezik az Artemisia annua \u00f6sszes flavonoidj\u00e1r\u00f3l itthon \u00e9s k\u00fclf\u00f6ld\u00f6n. Gu \u00e9s munkat\u00e1rsai elemezt\u00e9k az Artemisia scoparia k\u00e9miai \u00f6sszet\u00e9tel\u00e9t, \u00e9s a f\u0151 flavonoidokat az Artemisia scoparia, 8,4 '- dihidroxi-3,7,2' - trimetoxiflavon, 3,5-dihidroxi-6,7,3 ', 4' - tetrametoxiflavon stb. form\u00e1j\u00e1ban azonos\u00edtott\u00e1k; Zhang \u00e9s munkat\u00e1rsai. tanulm\u00e1nyozta az \u00f6sszes flavonoidok extrakci\u00f3s m\u00f3dszer\u00e9t az Artemisia annua-ban, \u00e9s meg\u00e1llap\u00edtotta, hogy az \u00f6sszes flavonoidok legnagyobb hozam\u00e1t az Artemisia annua-ban a 85% metanolos oldattal 2 \u00f3r\u00e1n kereszt\u00fcl v\u00e9gzett Soxhlet extrakci\u00f3val kapta, m\u00edg a 70% etanolos oldattal 6 \u00f3r\u00e1n kereszt\u00fcl v\u00e9gzett extrakci\u00f3val alacsonyabb volt a hozam, de ipari termel\u00e9sre ez volt a legalkalmasabb. Az Artemisia annua \u00f6sszes flavonoidj\u00e1nak extrakci\u00f3j\u00e1r\u00f3l, tiszt\u00edt\u00e1si folyamat\u00e1nak optimaliz\u00e1l\u00e1s\u00e1r\u00f3l \u00e9s antioxid\u00e1ns aktivit\u00e1s\u00e1r\u00f3l nem k\u00e9sz\u00fcltek jelent\u00e9sek.<\/p>\n<p>Ennek alapj\u00e1n ez a tanulm\u00e1ny az Artemisia annua f\u00f6ld feletti sz\u00e1r\u00e1t \u00e9s leveleit haszn\u00e1lta k\u00eds\u00e9rleti anyagk\u00e9nt, optimaliz\u00e1lta az Artemisia annua \u00f6sszes flavonoidjainak etanolos extrakci\u00f3s folyamat\u00e1t a v\u00e1laszfel\u00fcleti m\u00f3dszertan seg\u00edts\u00e9g\u00e9vel, \u00e9s ennek alapj\u00e1n felt\u00e1rta az Artemisia annua \u00f6sszes flavonoidjainak makrop\u00f3rusos gyant\u00e1val t\u00f6rt\u00e9n\u0151 tiszt\u00edt\u00e1si felt\u00e9teleit. Az Artemisia annua \u00f6sszes flavonoidj\u00e1nak antioxid\u00e1ns aktivit\u00e1s\u00e1t elemezt\u00fck, hogy elm\u00e9leti alapot \u00e9s adathivatkoz\u00e1st biztos\u00edtsunk az Artemisia annua fejleszt\u00e9s\u00e9hez \u00e9s alkalmaz\u00e1s\u00e1hoz a gy\u00f3gy\u00e1szat, az eg\u00e9szs\u00e9g\u00fcgy \u00e9s az \u00e9lelmiszeripar ter\u00fclet\u00e9n.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7904\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-335.png\" alt=\"\" width=\"659\" height=\"179\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7905\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-281.png\" alt=\"\" width=\"327\" height=\"189\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-281.png 327w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-281-325x189.png 325w\" sizes=\"(max-width: 327px) 100vw, 327px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7906\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-262.png\" alt=\"\" width=\"322\" height=\"189\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7907\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-243.png\" alt=\"\" width=\"320\" height=\"187\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7908\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-20.jpg\" alt=\"\" width=\"312\" height=\"189\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7909\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-199.png\" alt=\"\" width=\"663\" height=\"211\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7910\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-182.png\" alt=\"\" width=\"662\" height=\"371\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7911\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-163.png\" alt=\"\" width=\"663\" height=\"442\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-163.png 663w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-163-650x433.png 650w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-163-325x217.png 325w\" sizes=\"(max-width: 663px) 100vw, 663px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7912\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-148.png\" alt=\"\" width=\"657\" height=\"895\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-148.png 657w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-148-529x720.png 529w\" sizes=\"(max-width: 657px) 100vw, 657px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7913\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-118.png\" alt=\"\" width=\"330\" height=\"173\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7914\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/11-111.png\" alt=\"\" width=\"321\" height=\"354\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7915\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/12-7.jpg\" alt=\"\" width=\"326\" height=\"184\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7916\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/13-5.jpg\" alt=\"\" width=\"326\" height=\"205\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7917\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/14-60.png\" alt=\"\" width=\"321\" height=\"177\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7918\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/15-43.png\" alt=\"\" width=\"322\" height=\"192\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7919\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/16-31.png\" alt=\"\" width=\"328\" height=\"185\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7920\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/17-24.png\" alt=\"\" width=\"336\" height=\"196\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7921\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/18-17.png\" alt=\"\" width=\"327\" height=\"179\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/18-17.png 327w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/18-17-325x179.png 325w\" sizes=\"(max-width: 327px) 100vw, 327px\" \/><br \/>\nA tanulm\u00e1ny az Anhui tartom\u00e1ny Feixi megy\u00e9j\u00e9b\u0151l gy\u0171jt\u00f6tt Artemisia annua f\u00f6ld feletti r\u00e9szeit haszn\u00e1lta anyagk\u00e9nt, \u00e9s az etanol t\u00e9rfogatfrakci\u00f3, az extrakci\u00f3s h\u0151m\u00e9rs\u00e9klet, a folyad\u00e9k-anyag ar\u00e1ny \u00e9s az extrakci\u00f3s id\u0151 hat\u00e1s\u00e1t elemezte az Artemisia annua teljes flavonoid extrakci\u00f3s tartalm\u00e1ra a v\u00e1laszfel\u00fcleti m\u00f3dszertan seg\u00edts\u00e9g\u00e9vel. Az Artemisia annua \u00f6sszes flavonoidj\u00e1nak etanolos extrakci\u00f3j\u00e1hoz az optim\u00e1lis elj\u00e1r\u00e1si felt\u00e9telek a k\u00f6vetkez\u0151k voltak: 70% etanol t\u00e9rfogatfrakci\u00f3, 20 ml etanoladag, 85 perc extrakci\u00f3s id\u0151 \u00e9s 40 \u2103 extrakci\u00f3s h\u0151m\u00e9rs\u00e9klet. A hagyom\u00e1nyos etanolos extrakci\u00f3s m\u00f3dszerrel \u00f6sszehasonl\u00edtva az ebben a k\u00eds\u00e9rletben kapott optim\u00e1lis extrakci\u00f3s folyamat felt\u00e9telei bizonyos m\u00e9rt\u00e9kig ler\u00f6vid\u00edtett\u00e9k az extrakci\u00f3s id\u0151t, elker\u00fclt\u00e9k a hossz\u00fa t\u00e1v\u00fa extrakci\u00f3 hat\u00e1s\u00e1t a hat\u00f3anyagokra, \u00e9s jav\u00edtott\u00e1k az \u00f6sszes flavonoidok extrakci\u00f3s mennyis\u00e9g\u00e9t \u00e9s hat\u00e9konys\u00e1g\u00e1t az Artemisia annua-ban.<\/p>\n<p>A makropor\u00f3zus gyanta tiszt\u00edt\u00f3 hat\u00e1s\u00e1ra vonatkoz\u00f3 k\u00eds\u00e9rlet az Artemisia annua \u00f6sszes flavonoidjaira vonatkoz\u00f3an meg\u00e1llap\u00edtotta, hogy az AB-8 magas adszorpci\u00f3s \u00e9s deszorpci\u00f3s sebess\u00e9ggel rendelkezett, 74,36% \u00e9s 85,32%, ami ide\u00e1lis makropor\u00f3zus gyant\u00e1v\u00e1 teszi az Artemisia annua \u00f6sszes flavonoidjainak adszorpci\u00f3j\u00e1ra \u00e9s elv\u00e1laszt\u00e1s\u00e1ra. A tiszt\u00edt\u00e1si folyamat sor\u00e1n c\u00e9lszer\u0171 az AB-8 gyanta statikus adszorpci\u00f3s idej\u00e9t az Artemisia annua \u00f6sszes flavonoidjai eset\u00e9ben 2 \u00f3r\u00e1ban szab\u00e1lyozni, 65,47% statikus adszorpci\u00f3s sebess\u00e9ggel; az Artemisia annua \u00f6sszes flavonoidjainak statikus deszorpci\u00f3j\u00e1nak optim\u00e1lis ideje 1.5 \u00f3ra, 74,63% statikus deszorpci\u00f3s r\u00e1t\u00e1val; Az AB-8 gyanta statikus adszorpci\u00f3j\u00e1nak optim\u00e1lis koncentr\u00e1ci\u00f3ja 1,2 mg\/ml az Artemisia annua \u00f6sszes flavonoid kivonat\u00e1hoz; Az AB-8 gyanta statikus deszorpci\u00f3j\u00e1nak optim\u00e1lis koncentr\u00e1ci\u00f3ja 50% etanol koncentr\u00e1ci\u00f3.<\/p>\n<p>A t\u00falzott m\u00e9rt\u00e9k\u0171 szabad gy\u00f6k\u00f6k s\u00falyosan befoly\u00e1solj\u00e1k az emberi eg\u00e9szs\u00e9get, potenci\u00e1lisan k\u00e1ros\u00edtj\u00e1k a biofilm-lipideket, sz\u00f6vetk\u00e1rosod\u00e1st okoznak, \u00e9s k\u00fcl\u00f6nb\u00f6z\u0151 betegs\u00e9gek kialakul\u00e1s\u00e1hoz vezetnek. A szabad gy\u00f6k\u00f6k emberi szervezetre gyakorolt k\u00e1ros hat\u00e1s\u00e1nak cs\u00f6kkent\u00e9se nagy kutat\u00e1si jelent\u0151s\u00e9ggel b\u00edr. A flavonoidok k\u00e9pesek a szabad gy\u00f6k\u00f6k elsz\u00edv\u00e1s\u00e1ra. A k\u00eds\u00e9rletben olyan mutat\u00f3kat v\u00e1lasztottunk, mint a reduk\u00e1l\u00f3 er\u0151 \u00e9s az ABTS+-, DPPH -, - OH, O2- - szabad gy\u00f6k\u00f6k elsz\u00edv\u00e1sa az Artemisia annua \u00f6sszes flavonoidj\u00e1nak antioxid\u00e1ns aktivit\u00e1s\u00e1nak elemz\u00e9s\u00e9re. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy az Artemisia annua-ban tal\u00e1lhat\u00f3 \u00f6sszes flavonoidok er\u0151s reduk\u00e1l\u00f3er\u0151vel rendelkeztek, \u00e9s j\u00f3 ABTS+-, DPPH -, - OH, \u00e9s O2- - elnyel\u0151 k\u00e9pess\u00e9get mutattak, ami d\u00f3zishat\u00e1st mutat. Tiszt\u00edt\u00e1s ut\u00e1n az Artemisia annua \u00f6sszes flavonoidj\u00e1nak antioxid\u00e1ns aktivit\u00e1sa fokoz\u00f3dott. Az Artemisia annua \u00f6sszes flavonoidjai potenci\u00e1lis \u00e9s alkalmaz\u00e1si \u00e9rt\u00e9kkel rendelkeznek, mint n\u00f6v\u00e9nyi flavonoid er\u0151forr\u00e1sok, \u00e9s term\u00e9szetes antioxid\u00e1nsk\u00e9nt haszn\u00e1lhat\u00f3k m\u00e9lyrehat\u00f3 kutat\u00e1sra, elm\u00e9leti alapot biztos\u00edtva az Artemisia annua \u00f6sszes flavonoidjainak tov\u00e1bbi fejleszt\u00e9s\u00e9hez \u00e9s alkalmaz\u00e1s\u00e1hoz.<\/p>","protected":false},"excerpt":{"rendered":"<p>Extraction, Purification, and Antioxidant Activity Analysis of Total Flavonoids from Artemisia annua Artemisia japonica Thunb. is a common species of Artemisia in the Asteraceae family in many parts of China. It is a perennial herb with a fragrant aroma and is a medicinal and edible plant. Its tender stems and leaves are edible and have [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Extraction, Purification, and Antioxidant Activity Analysis of Total Flavonoids from Artemisia annua - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/artemisia-annua\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Extraction, Purification, and Antioxidant Activity Analysis of Total Flavonoids from Artemisia annua - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Extraction, Purification, and Antioxidant Activity Analysis of Total Flavonoids from Artemisia annua Artemisia japonica Thunb. is a common species of Artemisia in the Asteraceae family in many parts of China. It is a perennial herb with a fragrant aroma and is a medicinal and edible plant. 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