{"id":7530,"date":"2024-08-06T20:21:56","date_gmt":"2024-08-06T20:21:56","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=7530"},"modified":"2024-08-06T20:21:56","modified_gmt":"2024-08-06T20:21:56","slug":"huangjingzi-and-wanjingzi","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/huangjingzi-es-wanjingzi\/","title":{"rendered":"A Huangjingzi \u00e9s a Wanjingzi jellemz\u0151 t\u00e9rk\u00e9peinek vizsg\u00e1lata \u00e9s a fenol- \u00e9s flavonoidtartalom meghat\u00e1roz\u00e1sa"},"content":{"rendered":"

A Huangjingzi \u00e9s a Wanjingzi jellemz\u0151 t\u00e9rk\u00e9peinek vizsg\u00e1lata \u00e9s a fenol- \u00e9s flavonoidtartalom meghat\u00e1roz\u00e1sa
\nA Huangjingzi, m\u00e1s n\u00e9ven Bujingzi vagy Huangjinzi a Verbenaceae csal\u00e1dba tartoz\u00f3 Vitex negundo L. var. cannabis (Sieb. et Zucc.) Hand Mazz. vagy Huangjingzi Vitex negundo L. n\u00f6v\u00e9ny sz\u00e1raz \u00e9s \u00e9rett term\u00e9se. Lejt\u0151k\u00f6n, \u00fatsz\u00e9leken vagy bokrokban n\u0151, \u00e9s f\u0151k\u00e9nt a Jangce foly\u00f3t\u00f3l d\u00e9lre fekv\u0151 k\u00fcl\u00f6nb\u00f6z\u0151 helyeken termesztik. A Wanjingzi, m\u00e1s n\u00e9ven Wanjingzi vagy Wanjingzi a Verbenaceae csal\u00e1dba tartoz\u00f3 Vitex trifolias L. var. simplicfolia Cham. vagy Vitex trifolias L. egylevel\u0171, sz\u00e1raz \u00e9s \u00e9rett term\u00e9se. El\u0151szeretettel terem a tengerparti strandokon \u00e9s t\u00f3parti ter\u00fcleteken, \u00e9s termesztik is. Elterjedt Hebei, Liaoning, Jiangsu, Guangdong \u00e9s m\u00e1s helyeken. A Verbenaceae csal\u00e1dba tartoz\u00f3 k\u00fcl\u00f6nb\u00f6z\u0151 n\u00f6v\u00e9nyfajok k\u00e9t term\u00e9se k\u00f6z\u00f6tti hasonl\u00f3s\u00e1g miatt a piacon id\u0151nk\u00e9nt el\u0151fordul, hogy \u00f6sszekeverik \u0151ket; A gy\u00f3gyhat\u00e1sokat tekintve a sz\u0151l\u0151vessz\u0151 k\u00e9pes a sz\u00e9lh\u0151 eloszlat\u00e1s\u00e1ra, a fej tiszt\u00edt\u00e1s\u00e1ra \u00e9s j\u00f3t\u00e9kony hat\u00e1s\u00e1ra, \u00e9s \u00e1ltal\u00e1ban sz\u00e9lh\u0151, hideg, fejf\u00e1j\u00e1s, \u00ednyduzzanat \u00e9s f\u00e1jdalom, k\u00f6nnyez\u0151, v\u00f6r\u00f6s szem, hom\u00e1lyos szem, sz\u00e9d\u00fcl\u00e9s \u00e9s sz\u00e9d\u00fcl\u00e9s eset\u00e9n haszn\u00e1lj\u00e1k; a Huangjingzi izzaszt\u00f3, k\u00f6h\u00f6gtet\u0151, asztma enyh\u00edt\u0151, qi szab\u00e1lyoz\u00f3, f\u00e1jdalomcsillap\u00edt\u00f3 \u00e9s a gyomorban l\u00e9v\u0151 szelet eloszlat\u00f3 hat\u00e1s\u00fa. \u00c1ltal\u00e1ban hideg k\u00f6h\u00f6g\u00e9s, kr\u00f3nikus v\u00e1lad\u00e9kos zih\u00e1l\u00e1s, epigasztrikus csukl\u00e1s \u00e9s \u00edz\u00fcleti reuma eset\u00e9n haszn\u00e1lj\u00e1k. A kett\u0151 hat\u00e9konys\u00e1ga \u00e9s klinikai alkalmaz\u00e1sa elt\u00e9r\u0151, \u00e9s nem szabad \u0151ket \u00f6sszekeverni. Ez\u00e9rt nagy jelent\u0151s\u00e9ge van egy olyan m\u00f3dszer kidolgoz\u00e1s\u00e1nak, amely hat\u00e9konyan k\u00fcl\u00f6nbs\u00e9get tud tenni a kett\u0151 k\u00f6z\u00f6tt.
\nA Polygonatum sibiricum k\u00e9miai \u00f6sszet\u00e9tele els\u0151sorban ill\u00f3olajokat, flavonoidokat, lign\u00e1nokat, diterp\u00e9neket, triterp\u00e9neket, szteroidokat, alkaloidokat \u00e9s kis molekul\u00e1j\u00fa fenolokat tartalmaz. K\u00e9miai \u00f6sszet\u00e9tel\u00e9re vonatkoz\u00f3an kev\u00e9s kutat\u00e1s van, m\u00edg a Polygonatum sibiricum k\u00e9miai \u00f6sszet\u00e9tele alapvet\u0151en megegyezik a Polygonatum sibiricum\u00e9val, f\u0151leg terp\u00e9nekb\u0151l, flavonoidokb\u00f3l \u00e9s fenolsavakb\u00f3l \u00e1ll. Mivel azonban a klinikai gyakorlatban \u00e1ltal\u00e1nosan haszn\u00e1lt hagyom\u00e1nyos k\u00ednai gy\u00f3gyszerk\u00e9nt a Polygonatum sibiricum min\u0151s\u00e9gi elemz\u00e9s\u00e9vel kapcsolatos kutat\u00e1sok viszonylag \u00e9rettek. Jelenleg az azonos\u00edt\u00e1s\u00e1ra vonatkoz\u00f3 kutat\u00e1sok els\u0151sorban a fizikai \u00e9s k\u00e9miai azonos\u00edt\u00e1sra, valamint a v\u00e9konyr\u00e9teg-azonos\u00edt\u00e1sra \u00f6sszpontos\u00edtanak. N\u00e9h\u00e1ny szakirodalom a tartalom meghat\u00e1roz\u00e1s\u00e1ra vonatkoz\u00f3 \u00f6sszehasonl\u00edt\u00f3 vizsg\u00e1latokr\u00f3l is besz\u00e1molt, de kev\u00e9s a jellemz\u0151 spektrumokra vonatkoz\u00f3 jelent\u00e9s. Ezenk\u00edv\u00fcl a Huangjingzi csak a k\u00fcl\u00f6nb\u00f6z\u0151 tartom\u00e1nyok helyi gy\u00f3gyszerk\u00e9sz\u00edtm\u00e9nyeinek gy\u00f3gy\u00e1szati szabv\u00e1nyaiban \u00e9s feldolgoz\u00e1si specifik\u00e1ci\u00f3iban szerepel, \u00e9s nem szerepel a K\u00ednai N\u00e9pk\u00f6zt\u00e1rsas\u00e1g gy\u00f3gyszerk\u00f6nyv\u00e9nek 2020-as kiad\u00e1s\u00e1ban. A k\u00fcl\u00f6nb\u00f6z\u0151 r\u00e9gi\u00f3k szabv\u00e1nyai \u00e9s feldolgoz\u00e1si el\u0151\u00edr\u00e1sai csak n\u00e9h\u00e1ny alapvet\u0151 elemet \u00edrnak el\u0151, mint p\u00e9ld\u00e1ul a jellemz\u0151i, az azonos\u00edt\u00e1sa \u00e9s a feldolgoz\u00e1sa. A jelenlegi jogi el\u0151\u00edr\u00e1sok nem tudj\u00e1k objekt\u00edven meg\u00edt\u00e9lni a Huangjingzi eredetis\u00e9g\u00e9t a megjelen\u00e9se alapj\u00e1n, \u00e9s nem tudj\u00e1k \u00e9rt\u00e9kelni az el\u0151nyeit \u00e9s h\u00e1tr\u00e1nyait sem. Ezenk\u00edv\u00fcl a hagyom\u00e1nyos k\u00ednai orvosl\u00e1s \u00faj t\u00edpus\u00fa f\u0151zetdarabjai, mint p\u00e9ld\u00e1ul a t\u00f6r\u00f6tt fal\u00fa f\u0151zetdarabok, az ultrafinom porok \u00e9s a formula granul\u00e1tumai elvesztett\u00e9k eredeti megjelen\u00e9si form\u00e1jukat a hagyom\u00e1nyos f\u0151zetdarabokhoz k\u00e9pest. Ez\u00e9rt nagy jelent\u0151s\u00e9ggel b\u00edr a Huangjingzi min\u0151s\u00e9g\u00e9rt\u00e9kel\u00e9s\u00e9nek m\u00e9lyrehat\u00f3bb kutat\u00e1sa. Az elm\u00falt \u00e9vekben a jellemz\u0151\/ujjlenyomat spektrumok l\u00e9trehoz\u00e1sa \u00e9s nagyfelbont\u00e1s\u00fa t\u00f6megspektrometri\u00e1val val\u00f3 kombin\u00e1l\u00e1sa az anyagi alapjuk tanulm\u00e1nyoz\u00e1s\u00e1ra a hagyom\u00e1nyos k\u00ednai gy\u00f3gy\u00e1szat min\u0151s\u00e9g\u00e9rt\u00e9kel\u00e9si rendszer\u00e9nek l\u00e9trehoz\u00e1s\u00e1ra szolg\u00e1l\u00f3 \u00e1ltal\u00e1nos m\u00f3dszerr\u00e9 v\u00e1lt. Ez\u00e9rt ez a tanulm\u00e1ny ezt a m\u00f3dszert k\u00edv\u00e1nja alkalmazni a Huangjingzi \u00e9s a Wanjingzi \u00f6sszehasonl\u00edt\u00e1s\u00e1ra \u00e9s tanulm\u00e1nyoz\u00e1s\u00e1ra, hogy elm\u00e9leti alapot ny\u00fajtson klinikai alkalmaz\u00e1sukhoz.<\/p>\n

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Ez a tanulm\u00e1ny a Huangjingzi \u00e9s a Wanjingzi szerves savak \u00e9s flavonoidok k\u00e9miai \u00f6sszetev\u0151ire \u00f6sszpontos\u00edt, \u00e9s l\u00e9trehoz egy UPLC jellegzetes t\u00e9rk\u00e9pez\u00e9si m\u00f3dszert a szerves savak \u00e9s flavonoidok k\u00e9miai \u00f6sszetev\u0151ire. Kilenc komponenst azonos\u00edtottak nagyfelbont\u00e1s\u00fa t\u00f6megspektrometri\u00e1val, nevezetesen a szerves savkomponensek protokatechuinsav, protokatechuialdehid, 4-hidroxi-benzoesav \u00e9s a flavonoidkomponensek paeoniflorin, izopaeoniflorin, bojtos vitexin, vitexin \u00e9s izopaeoniflorin. Ez azt jelzi, hogy a Huangjingzi \u00e9s a Wanjingzi f\u0151 k\u00e9miai \u00f6sszetev\u0151i a szerves savak \u00e9s a flavonoidok, ami \u00f6sszhangban van az irodalmi jelent\u00e9sekkel. Azonban a k\u00e9t komponensnek van n\u00e9mi elt\u00e9r\u00e9se, \u00e9s mindegyiknek megvannak a maga egyedi \u00f6sszetev\u0151i. Ezen t\u00falmen\u0151en, a t\u00f6bbindex-tartalom meghat\u00e1roz\u00e1sa azt jelzi, hogy a Huangjingzi \u00e9s a Wanjingzi f\u0151 k\u00e9miai \u00f6sszetev\u0151i a szerves savak \u00e9s a flavonoidok. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy a k\u00f6z\u00f6s komponensek mennyis\u00e9gi k\u00fcl\u00f6nbs\u00e9gek is vannak, \u00e9s a kett\u0151 k\u00f6z\u00f6tti k\u00f6vetkezetlen anyagi alap lehet az oka ezen \u00f6sszetev\u0151k k\u00f6vetkezetlen hat\u00e9konys\u00e1g\u00e1nak \u00e9s klinikai alkalmaz\u00e1s\u00e1nak, K\u00f6z\u00fcl\u00fck a Huangjingziben tal\u00e1lhat\u00f3 vitexin \u00e9s izovitexin flavonoid komponensek. Egyes irodalmi adatok szerint ezek az \u00f6sszetev\u0151k j\u00f3 farmakol\u00f3giai hat\u00e1st mutattak a sz\u00edvizom iszk\u00e9mia elleni k\u00fczdelemben, az antioxid\u00e1ci\u00f3ban, a gyullad\u00e1scs\u00f6kkent\u00e9sben, a hipoglik\u00e9mi\u00e1ban, a daganatellenes \u00e9s egy\u00e9b vonatkoz\u00e1sokban. Ugyanakkor vannak olyan irodalmi jelent\u00e9sek is, amelyek szerint a vitexinnek k\u00fcl\u00f6nb\u00f6z\u0151 farmakol\u00f3giai hat\u00e1sai vannak, p\u00e9ld\u00e1ul agyv\u00e9delem, sz\u00edvizomv\u00e9delem, csontv\u00e9delem, daganatellenes, v\u00edrusellenes, gyullad\u00e1scs\u00f6kkent\u0151 stb. A klinikai gyakorlatban amellett, hogy a vitexinhez hasonl\u00f3an megf\u00e1z\u00e1s, k\u00f6h\u00f6g\u00e9s, kr\u00f3nikus h\u00f6rghurut \u00e9s asztma kezel\u00e9s\u00e9re haszn\u00e1lj\u00e1k, epigasztrikus csukl\u00e1s \u00e9s \u00edz\u00fcleti reuma kezel\u00e9s\u00e9re is alkalmazhat\u00f3. Felt\u00e9telez\u00e9sek szerint ez a vitexin \u00e9s az izovitexin egyedi \u00f6sszetev\u0151inek farmakol\u00f3giai hat\u00e1s\u00e1val f\u00fcgghet \u00f6ssze. Ezenk\u00edv\u00fcl a Fructus Polygoni Multifaceusban nem mutatt\u00e1k ki a vitexint \u00e9s az izovitexint, amelyek a Fructus Polygoni Multifaceus specifikus \u00f6sszetev\u0151i, \u00e9s a k\u00fcl\u00f6nb\u00f6z\u0151 eredet\u0171 Fructus Polygoni Multifaceus gy\u00f3gy\u00e1szati anyagokban l\u00e9v\u0151 k\u00fcl\u00f6nbs\u00e9geket t\u00fckr\u00f6zhetik. Javasoljuk, hogy a Fructus Polygoni Multifaceus specifikus \u00e9rt\u00e9kel\u00e9si indik\u00e1toraik\u00e9nt a vitexin \u00e9s az izovitexin mutat\u00f3kat v\u00e1lasszuk, \u00e9s az \u00e1tfog\u00f3 \u00e9rt\u00e9kel\u00e9shez kombin\u00e1ljuk \u0151ket m\u00e1s, magasabb tartalm\u00fa \u00f6sszetev\u0151kkel. Ez nemcsak a Fructus Polygoni Multifaceus hiteless\u00e9g\u00e9t k\u00fcl\u00f6nb\u00f6ztetheti meg, hanem a k\u00fcl\u00f6nb\u00f6z\u0151 forr\u00e1sokb\u00f3l sz\u00e1rmaz\u00f3 Fructus Polygoni Multifaceus min\u0151s\u00e9g\u00e9nek \u00e9rt\u00e9kel\u00e9s\u00e9t is t\u00fckr\u00f6zheti.<\/p>\n

Az ebben a tanulm\u00e1nyban l\u00e9trehozott UPLC-t\u00e9rk\u00e9pes m\u00f3dszer \u00e1tfog\u00f3an t\u00fckr\u00f6zi a Polygonatum sibiricum k\u00e9miai \u00f6sszet\u00e9tel\u00e9t, \u00e9s ugyanezzel a m\u00f3dszerrel 9 hozz\u00e1rendelt jellemz\u0151 komponenst hat\u00e1roz meg. Az elemz\u00e9si m\u00f3dszer gyors \u00e9s egyszer\u0171, \u00e9s hat\u00e9konyan k\u00fcl\u00f6nbs\u00e9get tud tenni a Polygonatum sibiricum \u00e9s a Sophora japonica k\u00f6z\u00f6tt. A szerves savakat \u00e9s a flavonoid komponenseket vizsg\u00e1lt\u00e1k, ami alapot ny\u00fajt a Polygonatum sibiricum tov\u00e1bbi kutat\u00e1s\u00e1hoz \u00e9s min\u0151s\u00e9gellen\u0151rz\u00e9s\u00e9hez.<\/p>","protected":false},"excerpt":{"rendered":"

Study on the characteristic maps and determination of phenolic and flavonoid contents in Huangjingzi and Wanjingzi Huangjingzi, also known as Bujingzi or Huangjinzi, is a dry and mature fruit of the plant Vitex negundo L. var. cannabis (Sieb. et Zucc.) Hand Mazz. or Huangjingzi Vitex negundo L. in the family Verbenaceae. It grows on slopes, […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nStudy on the characteristic maps and determination of phenolic and flavonoid contents in Huangjingzi and Wanjingzi - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/huangjingzi-es-wanjingzi\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study on the characteristic maps and determination of phenolic and flavonoid contents in Huangjingzi and Wanjingzi - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Study on the characteristic maps and determination of phenolic and flavonoid contents in Huangjingzi and Wanjingzi Huangjingzi, also known as Bujingzi or Huangjinzi, is a dry and mature fruit of the plant Vitex negundo L. var. cannabis (Sieb. et Zucc.) Hand Mazz. or Huangjingzi Vitex negundo L. in the family Verbenaceae. 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