{"id":7162,"date":"2024-08-06T18:47:44","date_gmt":"2024-08-06T18:47:44","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=7162"},"modified":"2024-08-06T18:47:44","modified_gmt":"2024-08-06T18:47:44","slug":"number-nine-li-xiang-iii","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/number-nine-li-xiang-iii\/","title":{"rendered":"Tanulm\u00e1ny a n\u00e9gyes sz\u00e1m\u00fa kilences Li Xiang (III) n\u00e9gyes sz\u00e1m\u00fa etnikai gy\u00f3gyszer k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek \u00e9s citotoxikus aktivit\u00e1s\u00e1nak vizsg\u00e1lata"},"content":{"rendered":"<p>Tanulm\u00e1ny a n\u00e9gyes sz\u00e1m\u00fa kilences Li Xiang (III) n\u00e9gyes sz\u00e1m\u00fa etnikai gy\u00f3gyszer k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek \u00e9s citotoxikus aktivit\u00e1s\u00e1nak vizsg\u00e1lata<br \/>\nAz Aquilaria nemzets\u00e9gben vil\u00e1gszerte 14 faj \u00e9s 2 fajta tal\u00e1lhat\u00f3, ebb\u0151l 9 faj \u00e9s 1 fajta K\u00edn\u00e1ban. A Murraya nemzets\u00e9gbe tartoz\u00f3 n\u00f6v\u00e9nyek gy\u00f3gy\u00e1szati nyilv\u00e1ntart\u00e1sa a \"Lingnan Medicinal Collection Record\"-al kezd\u0151d\u00f6tt. Jelenleg a \"K\u00ednai Gy\u00f3gyszerk\u00f6nyv\" (2020-as kiad\u00e1s) k\u00e9t fajt tartalmaz: Jack \u00e9s a Murraya panaculata (L.) var. exotica (L.) Huang. A modern farmakol\u00f3giai kutat\u00e1sok kimutatt\u00e1k, hogy az Aquilaria nemzets\u00e9ghez tartoz\u00f3 gy\u00f3gyn\u00f6v\u00e9nyek k\u00e9pesek a szervezet immunrendszer\u00e9nek fokoz\u00e1s\u00e1ra, a bakt\u00e9riumokkal szembeni ellen\u00e1ll\u00e1sra, a gyullad\u00e1s \u00e9s az \u00e9rz\u00e9stelen\u00edt\u00e9s cs\u00f6kkent\u00e9s\u00e9re, a v\u00e9rcukorszint cs\u00f6kkent\u00e9s\u00e9re, a qi-kering\u00e9s el\u0151seg\u00edt\u00e9s\u00e9re \u00e9s a f\u00e1jdalom enyh\u00edt\u00e9s\u00e9re, valamint a v\u00e9rkering\u00e9s el\u0151seg\u00edt\u00e9s\u00e9re \u00e9s a v\u00e9r pang\u00e1s\u00e1nak megsz\u00fcntet\u00e9s\u00e9re; A modern gy\u00f3gyszerk\u00e9miai kutat\u00e1sok kimutatt\u00e1k, hogy els\u0151sorban olyan k\u00e9miai \u00f6sszetev\u0151ket tartalmaz, mint a karbazol-alkaloidok, flavonoidok \u00e9s kumarinok.<br \/>\nA Murraya tetramera Huang, mint a Murraya nemzets\u00e9g egyik faja, els\u0151sorban K\u00edna Guangdong, Hainan, Guangxi \u00e9s Yunnan tartom\u00e1nyaiban elterjedt, m\u00e9szk\u0151vel bor\u00edtott lejt\u0151k\u00f6n n\u0151. Yunnan etnikai kisebbs\u00e9gi ter\u00fcletein (Yi, Li, Miao, Hui, Zhuang, Dai) sz\u00e1r\u00edtott leveleit gy\u00f3gyszerk\u00e9nt haszn\u00e1lj\u00e1k az emberek. A Si Shu Jiu Li Xiang gy\u00f3gy\u00e1szati feljegyz\u00e9se el\u0151sz\u00f6r a \"Wenshan Chinese Herbal Medicine\" c\u00edm\u0171 k\u00f6nyvben jelent meg, majd k\u00e9s\u0151bb a \"Yunnan Province Chinese Herbal Medicine Standards\" (2005-\u00f6s kiad\u00e1s) (1. k\u00f6tet: Yi Ethnic Medicine) c\u00edm\u0171 k\u00f6nyvben etnikai gy\u00f3gyszerk\u00e9nt szerepelt. A \"National Compilation of Chinese Herbal Medicines\" (National Compilation of Chinese Herbal Medicines) (2. k\u00f6tet, 1978) feljegyzi, hogy \"Murraya tetramera Huang, a Rutaceae csal\u00e1dba tartoz\u00f3 n\u00f6v\u00e9nyt a leveleivel \u00e9s gy\u00f6kereivel gy\u00f3gyszerk\u00e9nt haszn\u00e1lj\u00e1k. A leveleket \u00e9s a gy\u00f6kereket ny\u00e1ron \u00e9s \u0151sszel szedik le, megmoss\u00e1k \u00e9s szeletekre v\u00e1gj\u00e1k, \u00e9s frissen haszn\u00e1lhat\u00f3k, vagy \u00e1rny\u00e9kban sz\u00e1r\u00edtj\u00e1k k\u00e9s\u0151bbi felhaszn\u00e1l\u00e1s c\u00e9lj\u00e1b\u00f3l; F\u0171szeres \u00e9s meleg jelleg\u0171, a t\u00fcd\u0151- \u00e9s m\u00e1jmeridi\u00e1nokhoz tartozik. A Si Shu Jiu Li Xiang hat\u00e1s\u00e1ra eloszlatja a szelet, enyh\u00edti a f\u00e1jdalmat, el\u0151seg\u00edti a v\u00e9rkering\u00e9st \u00e9s eloszlatja a v\u00e9r pang\u00e1s\u00e1t. A kutat\u00f3csoport meg\u00e1llap\u00edtotta, hogy a Ganoderma lucidum sz\u00e1r\u00edtott leveleinek etanolos kivonat\u00e1b\u00f3l \u00e9s ill\u00f3olaj\u00e1b\u00f3l k\u00e9sz\u00fclt injekci\u00f3k a t\u00fcd\u0151r\u00e1k kezel\u00e9s\u00e9re. Viszonylag kev\u00e9s kutat\u00e1s van azonban a Ganoderma lucidum farmakol\u00f3giai anyagalapj\u00e1r\u00f3l a tumorsejtek prolifer\u00e1ci\u00f3j\u00e1nak g\u00e1tl\u00e1s\u00e1ban. Ez\u00e9rt ebben a k\u00eds\u00e9rletben 95% etanolt haszn\u00e1ltak extrakci\u00f3s old\u00f3szerk\u00e9nt, \u00e9s a hideg impregn\u00e1l\u00e1si m\u00f3dszert alkalmazt\u00e1k a Yunnanb\u00f3l gy\u0171jt\u00f6tt N\u00e9gy sz\u00e1m kilenc lik\u0151r kivon\u00e1s\u00e1ra, sz\u0171r\u00e9s\u00e9re, koncentr\u00e1l\u00e1s\u00e1ra \u00e9s paszta k\u00e9sz\u00edt\u00e9s\u00e9re; Oldjuk fel a kivonatot meleg v\u00edzben, \u00e9s az old\u00f3szer polarit\u00e1s\u00e1nak megfelel\u0151en egym\u00e1s ut\u00e1n extrah\u00e1ljuk. Hagyom\u00e1nyos oszlopkromatogr\u00e1fi\u00e1t haszn\u00e1ltunk az etil-acet\u00e1t kivonat elv\u00e1laszt\u00e1s\u00e1ra \u00e9s tiszt\u00edt\u00e1s\u00e1ra; Modern spektroszk\u00f3piai technik\u00e1k alkalmaz\u00e1s\u00e1val \u00e9s irodalmi adatok \u00f6sszehasonl\u00edt\u00e1s\u00e1val azonos\u00edtottuk a vegy\u00fcletek szerkezet\u00e9t; \u00d6t tumorsejtet (HL-60 hum\u00e1n leuk\u00e9mi\u00e1s tumorsejtvonal, A-549 hum\u00e1n t\u00fcd\u0151 adenokarcin\u00f3ma sejtvonal, SMMC-7721 hum\u00e1n m\u00e1jr\u00e1k sejtvonal, SW-480 hum\u00e1n vastagb\u00e9lr\u00e1k sejtvonal \u00e9s MCF-7 hum\u00e1n eml\u0151r\u00e1k sejtvonal) haszn\u00e1ltunk modellk\u00e9nt az egyes k\u00e9miai \u00f6sszetev\u0151k g\u00e1tl\u00f3 hat\u00e1s\u00e1nak vizsg\u00e1lat\u00e1ra az \u00f6t tumorsejt prolifer\u00e1ci\u00f3j\u00e1ra. E tanulm\u00e1ny eredm\u00e9nyei gazdag\u00edtott\u00e1k a Silurus odorata Thunb k\u00e9miai \u00f6sszetev\u0151inek kutat\u00e1si tartalm\u00e1t, valamint anyagi alapot \u00e9s adatt\u00e1mogat\u00e1st ny\u00fajtottak a Silurus odorata Thunb nemzeti gy\u00f3gyszer hat\u00e9konys\u00e1g\u00e1nak tov\u00e1bbi felt\u00e1r\u00e1s\u00e1hoz.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7163\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-284.png\" alt=\"\" width=\"781\" height=\"303\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-284.png 781w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-284-768x298.png 768w\" sizes=\"(max-width: 781px) 100vw, 781px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7164\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-236.png\" alt=\"\" width=\"784\" height=\"457\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-236.png 784w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-236-768x448.png 768w\" sizes=\"(max-width: 784px) 100vw, 784px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7165\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-222.png\" alt=\"\" width=\"781\" height=\"164\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-222.png 781w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-222-768x161.png 768w\" sizes=\"(max-width: 781px) 100vw, 781px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7166\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-200.png\" alt=\"\" width=\"782\" height=\"177\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-200.png 782w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-200-768x174.png 768w\" sizes=\"(max-width: 782px) 100vw, 782px\" \/><br \/>\nEbben a k\u00eds\u00e9rletben 15 vegy\u00fcletet izol\u00e1ltak \u00e9s azonos\u00edtottak a Four Number Nine Thyme alkoholos kivonat\u00e1nak etil-acet\u00e1t kivonat\u00e1b\u00f3l. Ezek k\u00f6z\u00fcl az 1. vegy\u00fclet egy flavonoid, a 2-7. vegy\u00fcletek fenilpropanoidok, a 8-15. vegy\u00fcletek pedig alkaloidok voltak; mind a 15 vegy\u00fcletet el\u0151sz\u00f6r izol\u00e1lt\u00e1k ebb\u0151l a n\u00f6v\u00e9nyb\u0151l; ez a k\u00eds\u00e9rlet vizsg\u00e1lta az 1-15. vegy\u00fcletek in vitro tumorsejt-prolifer\u00e1ci\u00f3t g\u00e1tl\u00f3 hat\u00e1s\u00e1t is. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy az alkaloid vegy\u00fcletek j\u00f3 g\u00e1tl\u00f3 hat\u00e1ssal voltak \u00f6t tumorsejtvonalra (HL-60, A-549, SMMC-7721, SW-480, MCF-7). A k\u00eds\u00e9rlet eredm\u00e9nyei gazdag\u00edtott\u00e1k a N\u00e9gy sz\u00e1m kilenc kakukkf\u0171 k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek \u00e9s farmakol\u00f3giai anyag\u00e1nak alapj\u00e1t, \u00e9s hivatkoz\u00e1si alapot szolg\u00e1ltattak a N\u00e9gy sz\u00e1m kilenc kakukkf\u0171 tumorsejt-prolifer\u00e1ci\u00f3ra gyakorolt g\u00e1tl\u00f3 hat\u00e1s\u00e1nak magyar\u00e1zat\u00e1hoz. A k\u00e9s\u0151bbi szakaszban metabolikus \u00e9s transzkriptomikai m\u00f3dszereket fognak alkalmazni a n\u00e9gy sz\u00e1mjegy\u0171 kilenc f\u0171szeres karbazol alkaloidok szint\u00e9zis\u00e9nek genetikai mechanizmus\u00e1nak, valamint a kapcsol\u00f3d\u00f3 vegy\u00fcletek c\u00e9lpontjainak \u00e9s mechanizmusainak tanulm\u00e1nyoz\u00e1s\u00e1ra a tumorsejtek prolifer\u00e1ci\u00f3j\u00e1nak g\u00e1tl\u00e1s\u00e1ban.<\/p>","protected":false},"excerpt":{"rendered":"<p>Study on the Chemical Composition and Cytotoxic Activity of Ethnic Medicine Four Number Nine Li Xiang (III) There are 14 species and 2 varieties of plants in the genus Aquilaria worldwide, including 9 species and 1 variety in China. The medicinal records of plants in the genus Murraya began with the &#8220;Lingnan Medicinal Collection Record&#8221;. [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Study on the Chemical Composition and Cytotoxic Activity of Ethnic Medicine Four Number Nine Li Xiang (III) - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/number-nine-li-xiang-iii\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study on the Chemical Composition and Cytotoxic Activity of Ethnic Medicine Four Number Nine Li Xiang (III) - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Study on the Chemical Composition and Cytotoxic Activity of Ethnic Medicine Four Number Nine Li Xiang (III) There are 14 species and 2 varieties of plants in the genus Aquilaria worldwide, including 9 species and 1 variety in China. The medicinal records of plants in the genus Murraya began with the &#8220;Lingnan Medicinal Collection Record&#8221;. 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The medicinal records of plants in the genus Murraya began with the &#8220;Lingnan Medicinal Collection Record&#8221;. 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