{"id":6642,"date":"2024-08-06T12:49:34","date_gmt":"2024-08-06T12:49:34","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=6642"},"modified":"2024-08-06T12:49:34","modified_gmt":"2024-08-06T12:49:34","slug":"primitive-leeches","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/primitiv-piocak\/","title":{"rendered":"Tanulm\u00e1ny a k\u00fcl\u00f6nb\u00f6z\u0151 primit\u00edv pi\u00f3c\u00e1k \u00e9s az azokb\u00f3l k\u00e9sz\u00fclt term\u00e9kek min\u0151s\u00e9g\u00e9r\u0151l"},"content":{"rendered":"<p>Tanulm\u00e1ny a k\u00fcl\u00f6nb\u00f6z\u0151 primit\u00edv pi\u00f3c\u00e1k \u00e9s az azokb\u00f3l k\u00e9sz\u00fclt term\u00e9kek min\u0151s\u00e9g\u00e9r\u0151l<br \/>\nA K\u00ednai N\u00e9pk\u00f6zt\u00e1rsas\u00e1g gy\u00f3gyszerk\u00f6nyv\u00e9nek (a tov\u00e1bbiakban: K\u00ednai Gy\u00f3gyszerk\u00f6nyv) 2020-as kiad\u00e1sa el\u0151\u00edrja, hogy a pi\u00f3c\u00e1k a pi\u00f3caf\u00e9l\u00e9k csal\u00e1dj\u00e1ba tartoz\u00f3 \u00e1llatok, p\u00e9ld\u00e1ul a Whitman pigra Whitman pi\u00f3ca, a Hirudo nipponica Whitman pi\u00f3ca vagy a Whitman acranulata Whitman f\u0171zfalev\u00e9l pi\u00f3ca sz\u00e1r\u00edtott eg\u00e9sz\u00e9t jelentik. \u00cdze s\u00f3s, keser\u0171 \u00e9s lapos; van egy kis m\u00e9reganyag, amely a m\u00e1jmeridi\u00e1nhoz tartozik. Funkci\u00f3ja a v\u00e9r megt\u00f6r\u00e9se \u00e9s a kering\u00e9s el\u0151seg\u00edt\u00e9se, a v\u00e9r pang\u00e1s\u00e1nak megsz\u00fcntet\u00e9se \u00e9s a stagn\u00e1l\u00e1s megsz\u00fcntet\u00e9se. \u00c1ltal\u00e1nosan haszn\u00e1lj\u00e1k a v\u00e9r pang\u00e1s\u00e1ra \u00e9s a meridi\u00e1n elz\u00e1r\u00f3d\u00e1s\u00e1ra, t\u00f6megek kezel\u00e9s\u00e9re, stroke hemiplegia, valamint es\u00e9sek \u00e9s s\u00e9r\u00fcl\u00e9sek kezel\u00e9s\u00e9re. Tanulm\u00e1nyok kimutatt\u00e1k, hogy a pi\u00f3c\u00e1k farmakol\u00f3giai hat\u00e1sai k\u00f6z\u00e9 els\u0151sorban a v\u00e9ralvad\u00e1sg\u00e1tl\u00f3, antitrombotikus, daganatellenes, hipolipid\u00e9mi\u00e1s \u00e9s gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1sok tartoznak, \u00e9s nagyon sz\u00e9les klinikai alkalmaz\u00e1suk van, bele\u00e9rtve a tromb\u00f3zis, a hiperlipid\u00e9mia, a magas v\u00e9rnyom\u00e1s, a cukorbetegs\u00e9g, a prosztatagyullad\u00e1s, a r\u00e1k, a visszerek, a medd\u0151s\u00e9g, a m\u00e1jzsugor \u00e9s m\u00e1s betegs\u00e9gek kezel\u00e9s\u00e9t. A pi\u00f3c\u00e1k f\u0151 \u00f6sszetev\u0151i makromolekul\u00e1ris vegy\u00fcletek, amelyek f\u0151k\u00e9nt feh\u00e9rj\u00e9ket \u00e9s 17 f\u00e9le aminosavat tartalmaznak, k\u00f6zt\u00fck 8, az emberi szervezet sz\u00e1m\u00e1ra esszenci\u00e1lis aminosavat. A hidroliz\u00e1lt aminosavtartalom el\u00e9rte a 49,4%-t; Ezenk\u00edv\u00fcl k\u00fcl\u00f6nb\u00f6z\u0151 anyagokat is tartalmaz, mint p\u00e9ld\u00e1ul hirudin, heparin, hisztamin, hirudin, glikolipidek, szfenoidok, szteroidok \u00e9s karboxil-\u00e9szterek.<br \/>\nA szakirodalmi \u00e1ttekint\u00e9s sor\u00e1n meg\u00e1llap\u00edt\u00e1st nyert, hogy a pi\u00f3c\u00e1kkal kapcsolatos jelenlegi kutat\u00e1sok a v\u00e9ralvad\u00e1sg\u00e1tl\u00f3 mechanizmusokra \u00e9s az aminosav-meghat\u00e1roz\u00e1sra \u00f6sszpontos\u00edtanak, \u00e9s csak korl\u00e1tozottan v\u00e9geznek \u00e1tfog\u00f3 vizsg\u00e1latokat a k\u00fcl\u00f6nb\u00f6z\u0151 primit\u00edv pi\u00f3c\u00e1k \u00e9s kever\u00e9keik min\u0151s\u00e9g\u00e9r\u0151l. A k\u00fcl\u00f6nb\u00f6z\u0151 primit\u00edv pi\u00f3c\u00e1k \u00e9s kever\u00e9keik k\u00f6z\u00f6tti azonos\u00edt\u00e1si vizsg\u00e1latok t\u00f6bbnyire a K\u00ednai Gy\u00f3gyszerk\u00f6nyv 2020-as kiad\u00e1sa szerinti tulajdons\u00e1gazonos\u00edt\u00e1son alapulnak. A pi\u00f3c\u00e1k piaca dr\u00e1ga \u00e9s kaotikus, \u00e9s a hagyom\u00e1nyos megjelen\u00e9s szerinti azonos\u00edt\u00e1s \u00f6nmag\u00e1ban nem k\u00e9pes gyorsan \u00e9s hat\u00e9konyan \u00e9rt\u00e9kelni a min\u0151s\u00e9g\u00fcket. R\u00e1ad\u00e1sul a megjelen\u00e9s szerinti azonos\u00edt\u00e1s nem alkalmazhat\u00f3 a pi\u00f3cakivonatokra \u00e9s -k\u00e9sz\u00edtm\u00e9nyekre, ami bizonyos korl\u00e1tokkal j\u00e1r. Ez\u00e9rt nagy jelent\u0151s\u00e9ggel b\u00edr egy gyors, tudom\u00e1nyos \u00e9s hat\u00e9kony \u00e9rt\u00e9kel\u00e9si m\u00f3dszer kidolgoz\u00e1sa. Ez a tanulm\u00e1ny HPLC-t haszn\u00e1lt a pi\u00f3c\u00e1k jellemz\u0151 spektrum\u00e1nak \u00e9s tartalom meghat\u00e1roz\u00e1si m\u00f3dszer\u00e9nek meg\u00e1llap\u00edt\u00e1s\u00e1ra. Ez a m\u00f3dszer \u00e1tfog\u00f3an \u00e9rt\u00e9keli a pi\u00f3c\u00e1kat \u00e9s a bel\u0151l\u00fck k\u00e9sz\u00fclt vegyes term\u00e9keket, tudom\u00e1nyos alapot biztos\u00edtva a pi\u00f3c\u00e1k \u00e9s a bel\u0151l\u00fck k\u00e9sz\u00fclt vegyes term\u00e9kek min\u0151s\u00e9g\u00e9nek \u00e9rt\u00e9kel\u00e9s\u00e9hez.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6643\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-245.png\" alt=\"\" width=\"789\" height=\"378\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-245.png 789w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-245-768x368.png 768w\" sizes=\"(max-width: 789px) 100vw, 789px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6644\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-205.png\" alt=\"\" width=\"784\" height=\"412\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-205.png 784w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-205-768x404.png 768w\" sizes=\"(max-width: 784px) 100vw, 784px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6645\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-192.png\" alt=\"\" width=\"787\" height=\"714\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-192.png 787w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-192-768x697.png 768w\" sizes=\"(max-width: 787px) 100vw, 787px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6646\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-18.jpg\" alt=\"\" width=\"687\" height=\"274\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6647\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-155.png\" alt=\"\" width=\"780\" height=\"266\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-155.png 780w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-155-768x262.png 768w\" sizes=\"(max-width: 780px) 100vw, 780px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6648\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-141.png\" alt=\"\" width=\"780\" height=\"253\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-141.png 780w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-141-768x249.png 768w\" sizes=\"(max-width: 780px) 100vw, 780px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6649\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-129.png\" alt=\"\" width=\"787\" height=\"297\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-129.png 787w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-129-768x290.png 768w\" sizes=\"(max-width: 787px) 100vw, 787px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6650\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-117.png\" alt=\"\" width=\"783\" height=\"311\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-117.png 783w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-117-768x305.png 768w\" sizes=\"(max-width: 783px) 100vw, 783px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6651\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-109.png\" alt=\"\" width=\"786\" height=\"257\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-109.png 786w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-109-768x251.png 768w\" sizes=\"(max-width: 786px) 100vw, 786px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6652\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-87.png\" alt=\"\" width=\"783\" height=\"199\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-87.png 783w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-87-768x195.png 768w\" sizes=\"(max-width: 783px) 100vw, 783px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6653\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/11-79.png\" alt=\"\" width=\"785\" height=\"503\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/11-79.png 785w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/11-79-768x492.png 768w\" sizes=\"(max-width: 785px) 100vw, 785px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6654\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/12-62.png\" alt=\"\" width=\"785\" height=\"178\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/12-62.png 785w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/12-62-768x174.png 768w\" sizes=\"(max-width: 785px) 100vw, 785px\" \/><br \/>\nA kromatogr\u00e1fi\u00e1s felt\u00e9telek optimaliz\u00e1l\u00e1sa. A jellegzetes spektrum meg\u00e1llap\u00edt\u00e1sa alapj\u00e1n ebben a tanulm\u00e1nyban ugyanezt a m\u00f3dszert alkalmaztuk a p\u00f3r\u00e9hagyma k\u00e9t jellegzetes komponens\u00e9nek, a p\u00f3r\u00e9hagyma C karboxilsz\u00e1rmaz\u00e9k\u00e1nak \u00e9s a p\u00f3r\u00e9hagyma B aminj\u00e1nak tartalm\u00e1nak meghat\u00e1roz\u00e1s\u00e1ra. 200-400 nm hull\u00e1mhossz-tartom\u00e1nyban di\u00f3dasoros detektort haszn\u00e1ltunk a vizsg\u00e1lati oldat teljes hull\u00e1mhossz\u00fa letapogat\u00e1s\u00e1ra. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy az egyes f\u0151 komponensek kromatogr\u00e1fi\u00e1s cs\u00facsai er\u0151s UV-abszorpci\u00f3t mutattak 254 nm hull\u00e1mhosszon. Ez\u00e9rt ugyanazokat a felt\u00e9teleket alkalmaztuk a pi\u00f3camint\u00e1k jellemz\u0151 spektrum\u00e1nak \u00e9s tartalm\u00e1nak elemz\u00e9s\u00e9re.<br \/>\nA funkci\u00f3t\u00e9rk\u00e9pek eredm\u00e9nyeinek elemz\u00e9se. A pi\u00f3ca a pi\u00f3c\u00e1k csal\u00e1dj\u00e1ba tartoz\u00f3 \u00e1llat, a Whitmania pigra Whitman pi\u00f3ca sz\u00e1r\u00edtott eg\u00e9sz teste. Gy\u00f3gy\u00e1szati tulajdons\u00e1gai lapos ors\u00f3 alak\u00faak. A K\u00ednai Gy\u00f3gyszerk\u00f6nyv 2020-as kiad\u00e1sa csak a nedvess\u00e9gtartalom, az \u00f6sszes hamutartalom, a savass\u00e1gi \u00e9s l\u00fagoss\u00e1gi vizsg\u00e1latok \u00e9s az antitrombinaktivit\u00e1s r\u00e9v\u00e9n ellen\u0151rzi a min\u0151s\u00e9g\u00e9t, \u00e9s m\u00e9g nem v\u00e9gzett differenci\u00e1lt jellemz\u00e9st a k\u00fcl\u00f6nb\u00f6z\u0151 szubsztr\u00e1tumok k\u00f6z\u00f6tt. Ebben a tanulm\u00e1nyban a k\u00fcl\u00f6nb\u00f6z\u0151 eredet\u0171 hirudo \u00e9s hamis\u00edtott anyagainak HPLC-jellemz\u0151 t\u00e9rk\u00e9peit \u00e1ll\u00edtott\u00e1k fel. A referenciaanyagok \u00f6sszehasonl\u00edt\u00e1s\u00e1val meger\u0151s\u00edt\u00e9st nyert, hogy a hirudo \u00f6t komponenst tartalmaz: uracil, hipoxantin, xantin, hirudin C-karboxilsz\u00e1rmaz\u00e9kok, hirudin B. Az irodalmi jelent\u00e9sek szerint a fenti pteridinvegy\u00fcletek hasonl\u00f3 szerkezet\u0171ek a trombocitaaggreg\u00e1ci\u00f3-ellenes gy\u00f3gyszerekhez, p\u00e9ld\u00e1ul a klopidogr\u00e9lhez, \u00e9s \u00fagy v\u00e9lj\u00fck, hogy ezek a komponensek lehetnek a hirudo akt\u00edv \u00f6sszetev\u0151i, amelyek trombocitaaggreg\u00e1ci\u00f3-ellenes szerepet j\u00e1tszanak. A hirudo t\u00f6bb jelentett farmakol\u00f3giai hat\u00e1sa els\u0151sorban v\u00e9ralvad\u00e1sg\u00e1tl\u00f3, antitrombotikus \u00e9s antiatheroszklerotikus hat\u00e1s\u00fa. Ezenk\u00edv\u00fcl vannak daganatellenes, gyullad\u00e1scs\u00f6kkent\u0151, fibr\u00f3zisellenes \u00e9s lipid\u00e9mi\u00e1s tev\u00e9kenys\u00e9gek, amelyek azt jelzik, hogy a kiv\u00e1lasztott jellemz\u0151 cs\u00facsok ebben a tanulm\u00e1nyban kapcsol\u00f3dnak A pi\u00f3c\u00e1k farmakol\u00f3giai tev\u00e9kenys\u00e9get j\u00e1tsz\u00f3 funkcion\u00e1lis anyagainak tiszt\u00e1z\u00e1sa \u00e9s a gy\u00f3gyszerek m\u00e1sodlagos kutat\u00e1s\u00e1nak \u00e9s fejleszt\u00e9s\u00e9nek el\u0151seg\u00edt\u00e9se nagy jelent\u0151s\u00e9ggel b\u00edr. Ugyanakkor a meg\u00e1llap\u00edtott m\u00f3dszerrel azonos\u00edtani lehet a k\u00fcl\u00f6nb\u00f6z\u0151 primit\u00edv pi\u00f3c\u00e1kat \u00e9s azok vegyes term\u00e9keit. A k\u00f6vetkez\u0151 l\u00e9p\u00e9s a m\u00f3dszer alkalmaz\u00e1si kutat\u00e1s\u00e1nak folytat\u00e1sa a kivonatokban \u00e9s k\u00e9sz\u00edtm\u00e9nyekben, referenci\u00e1t biztos\u00edtva a pi\u00f3c\u00e1s gy\u00f3gy\u00e1szati anyagok fejleszt\u00e9s\u00e9hez \u00e9s felhaszn\u00e1l\u00e1s\u00e1hoz.<br \/>\nA tartalmi meghat\u00e1roz\u00e1s eredm\u00e9nyeinek elemz\u00e9se. A jellegzetes t\u00e9rk\u00e9pek tanulm\u00e1nyoz\u00e1sa alapj\u00e1n ez a tanulm\u00e1ny kvantitat\u00edv m\u00f3don \u00f6t komponenst hat\u00e1rozott meg a pi\u00f3c\u00e1kban, k\u00f6zt\u00fck h\u00e1rom nukleozidvegy\u00fcletet, uracilt, hipoxantint, \u00e9s k\u00e9t szfenoidvegy\u00fcletet, a pi\u00f3camin C-karboxilsz\u00e1rmaz\u00e9kokat \u00e9s a pi\u00f3camin B-t. A megl\u00e9v\u0151 irodalmi jelent\u00e9sek szerint a nukleozidvegy\u00fcletek \u00e9s a szfenoidvegy\u00fcletek a pi\u00f3c\u00e1k min\u0151s\u00e9g\u00e9rt\u00e9kel\u00e9si mutat\u00f3ik\u00e9nt haszn\u00e1lhat\u00f3k. A k\u00eds\u00e9rleti eredm\u00e9nyek azt mutatt\u00e1k, hogy az uracil \u00e9s hipoxantin tartalomban bizonyos k\u00fcl\u00f6nbs\u00e9gek mutatkoztak a k\u00fcl\u00f6nb\u00f6z\u0151 primit\u00edv pi\u00f3c\u00e1k \u00e9s kever\u00e9keik k\u00f6z\u00f6tt. Az uracil \u00e9s hipoxantin \u00e1tlagos tartalma a k\u00f6vetkez\u0151 sorrendben alakult: pi\u00f3ca&gt;pi\u00f3ca&gt;f\u0171zpi\u00f3ca&gt;filippi pi\u00f3ca; A xantin \u00e1tlagos tartalma a k\u00f6vetkez\u0151: Pi\u00f3ca&gt;pi\u00f3ca&gt;filippinai pi\u00f3ca&gt;f\u0171zlevel\u0171 pi\u00f3ca; A pi\u00f3ca-amin C-karboxil-sz\u00e1rmaz\u00e9kainak \u00e1tlagos tartalma a k\u00f6vetkez\u0151: lev\u00e9lpi\u00f3ca&gt;pi\u00f3ca&gt;pi\u00f3ca&gt;pi\u00f3ca&gt;filippinai pi\u00f3ca; A pi\u00f3ca-amin B \u00e1tlagos tartalma a k\u00f6vetkez\u0151: lev\u00e9lpi\u00f3ca&gt;pi\u00f3ca&gt;pi\u00f3ca&gt;pi\u00f3ca&gt;filippinai pi\u00f3ca. A F\u00fcl\u00f6p-szigeteki pi\u00f3ca nem tartalmaz pi\u00f3ca-amin B-t, \u00e9s a hipoxantin-tartalom l\u00e9nyegesen alacsonyabb, mint a m\u00e1sik h\u00e1rom szubsztr\u00e1t eset\u00e9ben. Ez\u00e9rt a fenti komponensek tartalm\u00e1nak meghat\u00e1roz\u00e1sa alkalmas a v\u00edzi pi\u00f3c\u00e1k (bele\u00e9rtve a pi\u00f3c\u00e1t, a pi\u00f3c\u00e1t \u00e9s a lev\u00e9lpi\u00f3c\u00e1t) \u00e9s az orvosi pi\u00f3c\u00e1k (F\u00fcl\u00f6p-szigeteki pi\u00f3ca) megk\u00fcl\u00f6nb\u00f6ztet\u00e9s\u00e9re; Ezenk\u00edv\u00fcl a PLS-DA elemz\u00e9s a mint\u00e1ban l\u00e9v\u0151 8 jellegzetes cs\u00facs ter\u00fclet\u00e9t haszn\u00e1lja v\u00e1ltoz\u00f3k\u00e9nt, \u00e9s a jellegzetes cs\u00facsok ter\u00fclete szorosan \u00f6sszef\u00fcgg a megfelel\u0151 indik\u00e1tor komponensek tartalm\u00e1val. A \"2.4.5.\" pontban szerepl\u0151 PLS-DA anal\u00edzis eredm\u00e9nyeivel kombin\u00e1lva a hipoxantinhoz \u00e9s a xantinhoz tartoz\u00f3 jellemz\u0151 cs\u00facsok VIP \u00e9rt\u00e9kei nagyobbak, mint 1, \u00e9s a f\u0171zfalev\u00e9l pi\u00f3ca nem tartalmaz xantint. A m\u00e1sik h\u00e1rom primit\u00edv xantin \u00e1tlagos tartalma szint\u00e9n jelent\u0151s k\u00fcl\u00f6nbs\u00e9geket mutat, ami tov\u00e1bb jelzi, hogy az \u00f6t komponens tartalommeghat\u00e1roz\u00e1si indik\u00e1tork\u00e9nt val\u00f3 kiv\u00e1laszt\u00e1sa bizonyos tudom\u00e1nyos \u00e9rv\u00e9nyess\u00e9ggel b\u00edr.<br \/>\nA kutat\u00f3int\u00e9zet\u00fcnk \u00e1ltal kidolgozott m\u00f3dszer pontos, \u00e9rz\u00e9keny \u00e9s j\u00f3 specificit\u00e1s\u00fa. Egyidej\u0171leg k\u00e9pes a jellegzetes spektrumok elemz\u00e9s\u00e9re \u00e9s a pi\u00f3ca gy\u00f3gy\u00e1szati anyagok tartalm\u00e1nak \u00e9rt\u00e9kel\u00e9s\u00e9re. Min\u0151s\u00e9g\u00e9rt\u00e9kel\u00e9si m\u00f3dszerk\u00e9nt haszn\u00e1lhat\u00f3 k\u00fcl\u00f6nb\u00f6z\u0151 primit\u00edv pi\u00f3c\u00e1k \u00e9s kever\u00e9keik eset\u00e9ben, referenci\u00e1t biztos\u00edtva a pi\u00f3c\u00e1s gy\u00f3gy\u00e1szati anyagok min\u0151s\u00e9g\u00e9rt\u00e9kel\u00e9s\u00e9hez.<\/p>","protected":false},"excerpt":{"rendered":"<p>Study on the Quality of Different Primitive Leeches and Their Confused Products The 2020 edition of the Pharmacopoeia of the People&#8217;s Republic of China, hereinafter referred to as the Chinese Pharmacopoeia, stipulates that leeches are the dried whole of the leech family animals, such as the leech Whitman pigra Whitman, leech Hirudo nipponica Whitman, or [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - 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