{"id":5729,"date":"2024-08-04T20:53:53","date_gmt":"2024-08-04T20:53:53","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5729"},"modified":"2024-08-04T20:53:53","modified_gmt":"2024-08-04T20:53:53","slug":"poria-cocos-peel-and-poria-cocos","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/poria-cocos-hej-es-poria-cocos\/","title":{"rendered":"A Poria cocos h\u00e9j\u00e1ban \u00e9s a Poria cocosban tal\u00e1lhat\u00f3 triterp\u00e9noidok HPLC jellegzetes spektrum\u00e1nak \u00e9s k\u00e9miai mintafelismer\u00e9s\u00e9nek vizsg\u00e1lata"},"content":{"rendered":"<p>A Poria cocos h\u00e9j\u00e1ban \u00e9s a Poria cocosban tal\u00e1lhat\u00f3 triterp\u00e9noidok HPLC jellegzetes spektrum\u00e1nak \u00e9s k\u00e9miai mintafelismer\u00e9s\u00e9nek vizsg\u00e1lata<br \/>\nA Poria cocos, m\u00e1s n\u00e9ven Futu, Fuling, Songfu stb. a Poria cocos (Schw.) Wolf csal\u00e1dba tartoz\u00f3 sz\u00e1r\u00edtott gomba. \u00c9des \u00e9s k\u00f6nny\u0171 \u00edze van, enyhe term\u00e9szet\u0171, \u00e9s a sz\u00edv, a t\u00fcd\u0151, a l\u00e9p \u00e9s a vese meridi\u00e1nokban tal\u00e1lhat\u00f3. Hat\u00e1s\u00e1ra el\u0151seg\u00edti a v\u00edz besziv\u00e1rg\u00e1s\u00e1t, er\u0151s\u00edti a l\u00e9pet \u00e9s nyugtatja a sz\u00edvet. A Fuling szerepel a K\u00ednai N\u00e9pk\u00f6zt\u00e1rsas\u00e1g Gy\u00f3gyszerk\u00f6nyv\u00e9nek 2020-as kiad\u00e1s\u00e1ban (a tov\u00e1bbiakban \"K\u00ednai Gy\u00f3gyszerk\u00f6nyv\"), \u00e9s a hagyom\u00e1nyos k\u00ednai orvosl\u00e1s n\u00e9gy kincs\u00e9nek \u00e9s nyolc kincs\u00e9nek egyike, a \"T\u00edz formula \u00e9s kilenc ling\" n\u00e9ven ismert. A Poria cocos f\u0151 farmakol\u00f3giai anyagai a Poria cocos poliszacharidok \u00e9s a Poria cocos triterpenoidok. A modern farmakol\u00f3giai vizsg\u00e1latok kimutatt\u00e1k, hogy a Poria cocos triterpenoidok vizelethajt\u00f3, daganatellenes, immunszab\u00e1lyoz\u00f3, gyullad\u00e1scs\u00f6kkent\u0151, \u00f6reged\u00e9sg\u00e1tl\u00f3, hipoglik\u00e9mi\u00e1s \u00e9s lipidcs\u00f6kkent\u0151 hat\u00e1s\u00faak, \u00e9s jelenleg fontos mutat\u00f3k a Poria cocos min\u0151s\u00e9g\u00e9nek \u00e9s hat\u00e9konys\u00e1g\u00e1nak jellemz\u00e9s\u00e9re. Jelenleg a piacon forgalomban l\u00e9v\u0151 Poria cocos f\u0151 fajt\u00e1i termesztett fajt\u00e1k, \u00e9s a Poria cocos szeletek elt\u00e9r\u0151 eredete, feldolgoz\u00e1si m\u00f3dszerei \u00e9s specifik\u00e1ci\u00f3i befoly\u00e1solhatj\u00e1k a Poria cocos gy\u00f3gy\u00e1szati anyagok \u00e9s szeletek min\u0151s\u00e9g\u00e9t. A K\u00ednai Gy\u00f3gyszerk\u00f6nyv 2020-as kiad\u00e1sa csak v\u00e9konyr\u00e9teg-kromatogr\u00e1fi\u00e1t haszn\u00e1l a Poria cocos \u00e9s a Poria cocos k\u00e9reg gy\u00f3gy\u00e1szati anyagok min\u0151s\u00e9g\u00e9nek azonos\u00edt\u00e1s\u00e1ra \u00e9s ellen\u0151rz\u00e9s\u00e9re, ami nehezen t\u00fckr\u00f6zi teljes m\u00e9rt\u00e9kben a min\u0151s\u00e9g\u00fcket. Az ujjlenyomat-elemz\u00e9s a modern k\u00ednai orvosl\u00e1s ter\u00fclet\u00e9n a hagyom\u00e1nyos k\u00ednai gy\u00f3gyszerek min\u0151s\u00e9gellen\u0151rz\u00e9s\u00e9nek egyik sz\u00e9les k\u00f6rben elismert \u00e9s sz\u00e9les k\u00f6rben haszn\u00e1lt m\u00f3dszere. El\u0151nye a nagyfok\u00fa integrit\u00e1s \u00e9s az er\u0151s jellemz\u0151k, \u00e9s \u00f6sszhangban van a hagyom\u00e1nyos k\u00ednai orvosl\u00e1s t\u00f6bb \u00f6sszetev\u0151j\u00e9nek \u00e1tfog\u00f3 hat\u00e1saival. Lehet\u0151s\u00e9ge van a tov\u00e1bbi azonos\u00edt\u00e1sra, felismer\u00e9sre \u00e9s oszt\u00e1lyoz\u00e1sra. A k\u00e9miai mintafelismer\u00e9s k\u00e9pes elemezni az ujjlenyomat-spektrumok t\u00f6bbdimenzi\u00f3s inform\u00e1ci\u00f3it, pontosan t\u00fckr\u00f6zni a gy\u00f3gy\u00e1szati anyagok min\u0151s\u00e9gi k\u00fcl\u00f6nbs\u00e9geit, \u00e9s el\u00e9rni a gy\u00f3gy\u00e1szati anyagok min\u0151s\u00e9g\u00e9nek \u00e1tfog\u00f3 le\u00edr\u00e1s\u00e1t \u00e9s \u00e9sszer\u0171 \u00e9rt\u00e9kel\u00e9s\u00e9t. E tanulm\u00e1ny c\u00e9lja a Poria cocos (a Poria cocos epidermisz\u00e9b\u0151l sz\u00e1rmaz\u00f3) \u00e9s a Poria cocos (a Poria cocos h\u00e1mozott r\u00e9sz\u00e9b\u0151l sz\u00e1rmaz\u00f3) HPLC-ujjlenyomat-spektrumok l\u00e9trehoz\u00e1sa, \u00e9s az egyes k\u00f6z\u00f6s cs\u00facsok ujjlenyomat-spektrumokra gyakorolt hat\u00e1s\u00e1nak elemz\u00e9se mintafelismer\u00e9si m\u00f3dszerek seg\u00edts\u00e9g\u00e9vel. A f\u0151 cs\u00facsok \u00e9s a jellegzetes cs\u00facsok azonos\u00edt\u00e1sa lehet\u0151v\u00e9 teszi a Poria cocos \u00e9s a Poria cocos eg\u00e9sze k\u00f6z\u00f6tti k\u00fcl\u00f6nb\u00f6z\u0151 k\u00e9miai anyagok k\u00f6z\u00f6tti k\u00fcl\u00f6nbs\u00e9gek \u00e9rt\u00e9kel\u00e9s\u00e9t, ami alapot ny\u00fajt a Poria cocos gy\u00f3gy\u00e1szati anyagok min\u0151s\u00e9gellen\u0151rz\u00e9s\u00e9hez.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5730\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-171.png\" alt=\"\" width=\"664\" height=\"351\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5731\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-10.jpg\" alt=\"\" width=\"634\" height=\"915\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-10.jpg 634w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-10-499x720.jpg 499w\" sizes=\"(max-width: 634px) 100vw, 634px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5732\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-146.png\" alt=\"\" width=\"661\" height=\"437\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5733\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-131.png\" alt=\"\" width=\"663\" height=\"239\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5734\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-119.png\" alt=\"\" width=\"663\" height=\"229\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5735\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-109.png\" alt=\"\" width=\"664\" height=\"368\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5736\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-101.png\" alt=\"\" width=\"659\" height=\"243\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5737\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-93.png\" alt=\"\" width=\"658\" height=\"276\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5738\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-87.png\" alt=\"\" width=\"661\" height=\"201\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5739\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-69.png\" alt=\"\" width=\"658\" height=\"496\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5740\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/11-62.png\" alt=\"\" width=\"333\" height=\"404\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5741\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/12-50.png\" alt=\"\" width=\"664\" height=\"448\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5742\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/13-45.png\" alt=\"\" width=\"659\" height=\"273\" \/><\/p>\n<p>Ebben a tanulm\u00e1nyban metanolt haszn\u00e1ltak extrakci\u00f3s old\u00f3szerk\u00e9nt \u00e9s 30 percig tart\u00f3 ultrahangos kezel\u00e9st k\u00fcl\u00f6nb\u00f6z\u0151 mobil f\u00e1zisok (acetonitril v\u00edz, acetonitril-0,1% hangyasav v\u00edz, acetonitril-0,1% foszforsav v\u00edz, acetonitril-0,2% foszforsav v\u00edz, acetonitril-0.3% foszforsavas v\u00edz), k\u00fcl\u00f6nb\u00f6z\u0151 kromatogr\u00e1fi\u00e1s oszlopok [Agilent 5 TC-C18 (2) (250mm \u00d7 4,6mm, 5 \u03bc m), Welch Ultimate XB-C18 (250mm \u00d7 4,6mm, 5 \u03bc m), Agilent Eclipse Plus C18 (250mm \u00d7 4.6mm, 5 \u03bc m)], k\u00fcl\u00f6nb\u00f6z\u0151 t\u00e9rfogat\u00e1raml\u00e1si sebess\u00e9gek (1,0, 1,1, 1,2mL\/min), k\u00fcl\u00f6nb\u00f6z\u0151 oszloph\u0151m\u00e9rs\u00e9kletek (22, 25, 28 \u2103) \u00e9s k\u00fcl\u00f6nb\u00f6z\u0151 gy\u0171jt\u00e9si hull\u00e1mhosszok (203, 210, 242)]. V\u00e9g\u00fcl meghat\u00e1roztuk a nm hat\u00e1s\u00e1t az ujjlenyomat spektrum\u00e1ra, \u00e9s a kromatogr\u00e1fi\u00e1s felt\u00e9teleket \u00fagy hat\u00e1roztuk meg, hogy mozg\u00f3f\u00e1zisk\u00e9nt acetonitril 0,3% foszforsavas v\u00edz, Agilent 5 TC-C18 (2) (250 mm \u00d7 4,6 mm, 5 \u03bc m) kromatogr\u00e1fi\u00e1s oszlop, 1,0 ml\/perc t\u00e9rfogat\u00e1ram, 25 \u00b0C-os oszloph\u0151m\u00e9rs\u00e9klet \u00e9s v\u00e1ltoz\u00f3 hull\u00e1mhossz\u00fa gy\u0171jt\u00e9s mellett. Ilyen k\u00f6r\u00fclm\u00e9nyek k\u00f6z\u00f6tt az alapvonal stabil, a kromatogr\u00e1fi\u00e1s cs\u00facs alakja j\u00f3, \u00e9s az elv\u00e1laszt\u00e1si hat\u00e1s j\u00f3.<br \/>\nEnnek alapj\u00e1n a HPLC-m\u00f3dszerrel 14 t\u00e9tel ujjlenyomat-spektrum\u00e1t hat\u00e1rozt\u00e1k meg a k\u00fcl\u00f6nb\u00f6z\u0151 eredet\u0171 Poria cocos \u00e9s Poria cocos fajokb\u00f3l. \u00d6sszesen 15 k\u00f6z\u00f6s cs\u00facsot kalibr\u00e1ltak a Poria cocos \u00e9s a Poria cocos ujjlenyomat-spektrumok k\u00f6z\u00f6s m\u00f3dj\u00e1ban, \u00e9s 6 k\u00e9miai komponenst azonos\u00edtottak k\u00e9miai referenciastandardok seg\u00edts\u00e9g\u00e9vel: Poria cocos sav B, dehidrofum\u00e1rsav, Poria cocos sav A, dehidrofum\u00e1rsav, Poria cocos sav \u00e9s Poria cocos sav. A k\u00fcl\u00f6nb\u00f6z\u0151 eredet\u0171 Poria cocos b\u0151r \u00e9s feh\u00e9r Poria cocos mint\u00e1k 14 t\u00e9tel\u00e9nek klaszterez\u0151 elemz\u00e9s\u00e9vel, valamint a hasonl\u00f3s\u00e1gi adatokkal kombin\u00e1lva meg\u00e1llap\u00edthat\u00f3, hogy a k\u00fcl\u00f6nb\u00f6z\u0151 gy\u00f3gy\u00e1szati r\u00e9szekb\u0151l sz\u00e1rmaz\u00f3 Poria cocos mint\u00e1k csoportjai k\u00f6z\u00f6tt jelent\u0151s k\u00fcl\u00f6nbs\u00e9gek, a csoportokon bel\u00fcl pedig kis k\u00fcl\u00f6nbs\u00e9gek vannak. A feh\u00e9r Poria cocos mint\u00e1k \u00e9s a sz\u00e1rmaz\u00e1s k\u00f6z\u00f6tti korrel\u00e1ci\u00f3 er\u0151s. Ez\u00e9rt a mintafelismer\u00e9shez nem fel\u00fcgyelt PCA-m\u00f3dszert alkalmaztunk, \u00e9s a PCA eredm\u00e9nyei a 15 k\u00f6z\u00f6s cs\u00facsv\u00e1ltoz\u00f3t 2 Y1 \u00e9s Y2 f\u0151komponensre osztott\u00e1k. Az Y1 a 7 k\u00f6z\u00f6s kromatogr\u00e1fi\u00e1s cs\u00facs \u00e1tfog\u00f3 reakci\u00f3ja, bele\u00e9rtve a dehidrofum\u00e1rsav, dehidroporinsav \u00e9s p\u00f3rsav komponenseket, ami azt jelzi, hogy a 7 k\u00f6z\u00f6s kromatogr\u00e1fi\u00e1s cs\u00facs l\u00e9nyeges a poria cocos b\u0151r \u00e9s a feh\u00e9r poria cocos ujjlenyomat spektrum\u00e1nak vizsg\u00e1lat\u00e1hoz; Y2 8 kromatogr\u00e1fi\u00e1s cs\u00facs \u00e1tfog\u00f3 reakci\u00f3ja, bele\u00e9rtve a Poria cocos sav B, a Poria cocos sav A \u00e9s a Poria cocos sav, ami azt jelzi, hogy ez a 8 kromatogr\u00e1fi\u00e1s cs\u00facs a Poria cocos b\u0151r jellegzetes azonos\u00edt\u00f3 cs\u00facsak\u00e9nt szolg\u00e1lhat a Poria cocos b\u0151r \u00e9s a Poria cocos min\u0151s\u00e9g\u00e9nek egyidej\u0171 \u00e9rt\u00e9kel\u00e9se sor\u00e1n. A k\u00f6z\u00f6s cs\u00facsv\u00e1ltoz\u00f3 param\u00e9terek, amelyek jelent\u0151s hat\u00e1ssal vannak az ujjlenyomat spektrum\u00e1ra, az 1., 2. (Poria cocos sav B) \u00e9s a 7. kromatogr\u00e1fi\u00e1s cs\u00facs. A Poria cocos 15 k\u00f6z\u00f6s cs\u00facskomponens\u00e9nek tartalmi k\u00fcl\u00f6nbs\u00e9ge kisebb, mint a Poria cocos b\u0151r\u00e9. Val\u00f3j\u00e1ban e 15 k\u00f6z\u00f6s cs\u00facskomponens tartalma a feh\u00e9r Poria cocosban sokkal alacsonyabb, mint a Poria cocos b\u0151r\u00e9ben. Annak \u00e9rdek\u00e9ben, hogy a Poria cocos b\u0151r \u00e9s a feh\u00e9r Poria cocos ujjlenyomat k\u00f6z\u00f6s mint\u00e1zata teljesebb \u00e9s m\u00e9rhet\u0151bb legyen, a feh\u00e9r Poria cocos el\u0151\u00e1ll\u00edt\u00e1s\u00e1hoz egy koncentr\u00e1ci\u00f3s l\u00e9p\u00e9st is hozz\u00e1adtak.<br \/>\nA kutat\u00e1sok kimutatt\u00e1k, hogy az ebben a cikkben meghat\u00e1rozott m\u00f3dszer egyszer\u0171, megb\u00edzhat\u00f3 \u00e9s pontos, \u00e9s hivatkoz\u00e1si alapot ny\u00fajthat a Poria cocos \u00e9s a Poria cocos min\u0151s\u00e9gi \u00e9rt\u00e9kel\u00e9s\u00e9hez, szabv\u00e1nyos megfogalmaz\u00e1s\u00e1hoz \u00e9s \u00e9sszer\u0171 felhaszn\u00e1l\u00e1s\u00e1hoz.<\/p>","protected":false},"excerpt":{"rendered":"<p>Study on HPLC characteristic spectra and chemical pattern recognition of triterpenoids in Poria cocos peel and Poria cocos Poria cocos, also known as Futu, Fuling, Songfu, etc., is a dried fungus of the Poria cocos (Schw.) Wolf family. It has a sweet and light taste, a mild nature, and can be found in the heart, [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Study on HPLC characteristic spectra and chemical pattern recognition of triterpenoids in Poria cocos peel and Poria cocos - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/poria-cocos-hej-es-poria-cocos\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study on HPLC characteristic spectra and chemical pattern recognition of triterpenoids in Poria cocos peel and Poria cocos - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Study on HPLC characteristic spectra and chemical pattern recognition of triterpenoids in Poria cocos peel and Poria cocos Poria cocos, also known as Futu, Fuling, Songfu, etc., is a dried fungus of the Poria cocos (Schw.) Wolf family. 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