{"id":5266,"date":"2024-08-04T18:04:48","date_gmt":"2024-08-04T18:04:48","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5266"},"modified":"2024-08-04T18:04:48","modified_gmt":"2024-08-04T18:04:48","slug":"angiosperm-phylogeny-group","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/angiosperm-phylogeny-group\/","title":{"rendered":"A 7H-azul\u00e9n [1,2,3,3-i, j] izokinolin-7-on \u00f6sszetev\u0151inek elemz\u00e9se az Acorus nemzets\u00e9g hagyom\u00e1nyos k\u00ednai gy\u00f3gy\u00e1szat\u00e1ban UPLC-Q-TOF\/MS2 kombin\u00e1ci\u00f3s technol\u00f3gia alapj\u00e1n"},"content":{"rendered":"

A 7H-azul\u00e9n [1,2,3,3-i, j] izokinolin-7-on \u00f6sszetev\u0151inek elemz\u00e9se az Acorus nemzets\u00e9g hagyom\u00e1nyos k\u00ednai gy\u00f3gy\u00e1szat\u00e1ban UPLC-Q-TOF\/MS2 kombin\u00e1ci\u00f3s technol\u00f3gia alapj\u00e1n
\nAz APG IV rendszer az Angiosperm Phylogeny Group (APG) \u00e1ltal l\u00e9trehozott angiosperm oszt\u00e1lyoz\u00e1si rendszer negyedik kiad\u00e1sa. Az oszt\u00e1lyoz\u00e1si rendszer az Acorales-t az egyszik\u0171 n\u00f6v\u00e9nyek egy \u00e1g\u00e1nak tekinti a k\u00f6z\u00e9ps\u0151 angiosperm\u00e1k k\u00f6z\u00f6tt, \u00e9s az egyszik\u0171 n\u00f6v\u00e9nyek legalapvet\u0151bb csoportj\u00e1nak tekinti. Az Acorales alatt csak egy csal\u00e1d (Acoraceae) \u00e9s egy nemzets\u00e9g (Acorus) tal\u00e1lhat\u00f3, \u00e9s a gyakori n\u00f6v\u00e9nyek k\u00f6z\u00e9 tartozik az Acorus calamus L. \u00e9s az Acorus tatarinowii Schott. A K\u00ednai Gy\u00f3gyszerk\u00f6nyv 2020-as kiad\u00e1sa tartalmazza az Acori Tatarinowii riz\u00f3m\u00e1t \u00e9s az Acori Calami riz\u00f3m\u00e1t, amelyek mindkett\u0151 az Acori nemzets\u00e9g gy\u00f3gyn\u00f6v\u00e9nyei. Az Acori Calami Rhizome nev\u00e9t a tibeti gy\u00f3gy\u00e1szatban val\u00f3 haszn\u00e1lat\u00e1r\u00f3l kapta, eredeti n\u00f6v\u00e9nyei pedig az A. tatarinowii Schott \u00e9s az A. calamus L.. A modern gy\u00f3gyszer\u00e9szeti kutat\u00e1sok kimutatt\u00e1k, hogy az Acorus nemzets\u00e9g hagyom\u00e1nyos k\u00ednai gy\u00f3gyszere j\u00f3 hat\u00e1ssal van a tanul\u00e1s, a mem\u00f3ria \u00e9s a kognit\u00edv k\u00e9pess\u00e9gek jav\u00edt\u00e1s\u00e1ra. Az ut\u00f3bbi \u00e9vekben az olyan akt\u00edv \u00f6sszetev\u0151k mellett, mint az ill\u00f3olaj, a \u03b2-aszaron \u00e9s a szeszkviterp\u00e9nek, j\u00f3 hat\u00e1s\u00fa alkaloidokat is tal\u00e1ltak az Acorus nemzets\u00e9g hagyom\u00e1nyos k\u00ednai gy\u00f3gy\u00e1szat\u00e1ban. Lao \u00e9s munkat\u00e1rsai az Acorus tatarinowii-b\u00f3l tatarine A-t, catarine B-t \u00e9s catarine C-t izol\u00e1ltak. K\u00f6z\u00fcl\u00fck az Acorus tatarinowii e h\u00e1rom komponenst tartalmaz\u00f3 etil-acet\u00e1t kivonata \u00e9s n-butanol kivonata jelent\u0151sen jav\u00edthatja a szkopolamin induk\u00e1lta mem\u00f3riazavar modellben szenved\u0151 egerek mem\u00f3riazavar\u00e1t; Li \u00e9s munkat\u00e1rsai Acorus calamus A \u00e9s neo katarin alkaloidokat izol\u00e1ltak Acorus calamusb\u00f3l, amelyek j\u00f3 v\u00e9d\u0151hat\u00e1ssal rendelkeznek a s\u00e9r\u00fclt idegsejtekre.
\nAz Acorus calamus alkaloid egy szerkezetileg \u00faj tropoloisokinolin alkaloid (TA), k\u00e9miai neve 6-hidroxi-5,8-dimetoxi-7H-azuleno [1,2,3-i, j] izokinolin-7-one, j]izokinolin-7-one)\uff0c Alapvet\u0151 anyamagja a 7H-azul\u00e9n [1,2,3-i, j] izokinolin-7-one (7H-azuleno [1,2,3,3-i, j]izokinolin-7-one, r\u00f6vid\u00edtve 7H-AI7O, az 1. \u00e1br\u00e1n l\u00e1that\u00f3 v\u00e1zszerkezettel), az Acorus calamus alkaloid jelenleg az egyetlen olyan vegy\u00fclet, amelyet a term\u00e9szetben 7H-AI7O szerkezeti alapmaggal tal\u00e1lunk. Az Acorus calamus alkaloid mennyis\u00e9ge a n\u00f6v\u00e9nyekben azonban rendk\u00edv\u00fcl kicsi, mind\u00f6ssze 5 mg-ot izol\u00e1ltak 10 kg sz\u00e1r\u00edtott Acorus calamus gy\u00f6k\u00e9rb\u0151l \u00e9s sz\u00e1rb\u00f3l. Ez\u00e9rt, figyelembe v\u00e9ve a 7H-AI7O oszt\u00e1ly\u00fa komponensek szerkezeti jellemz\u0151it \u00e9s biol\u00f3giai aktivit\u00e1s\u00e1t, ez a cikk az Acorus calamus alkaloidokat haszn\u00e1lja referenciaanyagk\u00e9nt, a 7H-AI7O oszt\u00e1ly\u00fa komponenseket pedig megfigyel\u00e9si t\u00e1rgyk\u00e9nt, \u00e9s ultra-nagy teljes\u00edtm\u00e9ny\u0171 folyad\u00e9kkromatogr\u00e1fi\u00e1t alkalmaz? Az UPLC-Q-TOF\/MS2 tandem-kvadrupolos rep\u00fcl\u00e9si id\u0151 t\u00f6megspektrometri\u00e1s (UPLC-Q-TOF\/MS2) technol\u00f3gi\u00e1t alkalmazzuk a 7H-AI7O oszt\u00e1ly\u00fa komponensek \u00f6sszet\u00e9tel\u00e9nek \u00e9s eloszl\u00e1s\u00e1nak gyors nyomon k\u00f6vet\u00e9s\u00e9re \u00e9s azonos\u00edt\u00e1s\u00e1ra az Acorus nemzets\u00e9g hagyom\u00e1nyos k\u00ednai gy\u00f3gy\u00e1szat\u00e1ban. Ez bizonyos k\u00eds\u00e9rleti alapot biztos\u00edt ezen \u00f6sszetev\u0151k n\u00f6v\u00e9nyi forr\u00e1sainak tov\u00e1bbi gazdag\u00edt\u00e1s\u00e1hoz \u00e9s a kapcsol\u00f3d\u00f3 gy\u00f3gyszerek kifejleszt\u00e9s\u00e9hez.<\/p>\n

 <\/p>\n

\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"angiospermia filogenetikai csoportAz Acorus tatarinowii tibeti \u00e9s az Acorus tatarinowii tatarinowii tibeti fajt\u00e1ib\u00f3l jelenleg csak 5 t\u00e9telt gy\u0171jt\u00f6ttek ebben a k\u00eds\u00e9rletben, korl\u00e1tozott mintam\u00e9retekkel \u00e9s term\u0151ter\u00fcletekkel. Az eddig begy\u0171jt\u00f6tt mint\u00e1k alapj\u00e1n azonban m\u00e9g mindig lehet n\u00e9h\u00e1ny inform\u00e1ci\u00f3t szerezni. Mindk\u00e9t tibeti Acorus tatarinowii \u00e9s Acorus tatarinowii gy\u00f3gy\u00e1szati anyag tartalmaz 7H-AI7O oszt\u00e1ly\u00fa komponenseket; A 7H-AI7O komponenseket tartalmaz\u00f3 tibeti Acorus calamus sz\u00e9lesebb k\u00f6rben elterjedt a term\u0151ter\u00fcleten, mint az Acorus tatarinowii; Az Acorus tatarinowii-ban tal\u00e1lhat\u00f3 7H-AI7O vegy\u00fcletek szerkezeti t\u00edpusai b\u0151s\u00e9gesebbek, mint az Acorus tatarinowii-ban, de a kutat\u00e1si tartalom m\u00e9g nem teljes. A j\u00f6v\u0151ben tov\u00e1bb b\u0151v\u00edtj\u00fck a mintagy\u0171jt\u00e9s k\u00f6r\u00e9t, felhalmozzuk a mint\u00e1k sz\u00e1m\u00e1t, \u00e9s \u00e1tfog\u00f3an \u00e9s szisztematikusan elemezz\u00fck a k\u00fcl\u00f6nb\u00f6z\u0151 eredet\u0171 Acorus tatarinowii-ban l\u00e9v\u0151 7H-AI7O komponensek eloszl\u00e1s\u00e1t \u00e9s tartalmi v\u00e1ltoz\u00e1sait; Rendszeresen izol\u00e1lja az Acorus calamus gy\u00f3gy\u00e1szati anyagokat, amelyek b\u0151s\u00e9ges 7H-AI7O oszt\u00e1ly\u00fa komponenseket tartalmaznak, specifikus vegy\u00fcleteket nyer, tov\u00e1bb jav\u00edtja a 7H-AI7O oszt\u00e1ly\u00fa komponensek t\u00f6megspektrometri\u00e1s adatb\u00e1zis\u00e1t k\u00fcl\u00f6nb\u00f6z\u0151 szubsztituensekkel, \u00e9s k\u00eds\u00e9rleti alapot biztos\u00edt a 7H-AI7O oszt\u00e1ly\u00fa komponensek gyors \u00e9s pontos kimutat\u00e1s\u00e1hoz \u00e9s szerkezet\u00e9nek meghat\u00e1roz\u00e1s\u00e1hoz.<\/p>\n

A n\u00f6v\u00e9nyekb\u0151l sz\u00e1rmaz\u00f3 7H-AI7O mennyis\u00e9ge rendk\u00edv\u00fcl kicsi. Kor\u00e1bbi k\u00eds\u00e9rletek meg\u00e1llap\u00edtott\u00e1k, hogy az Acorus calamus alkaloidok (7H-AI7O szerkezet) \u00e9s az Acorus calamus alkaloidok A (AA szerkezet) egyszerre izol\u00e1lhat\u00f3k az Acorus calamusb\u00f3l. A k\u00e9t vegy\u00fclet k\u00f6z\u00f6tti szerkezeti k\u00fcl\u00f6nbs\u00e9g els\u0151sorban abban rejlik, hogy az el\u0151bbi a 7. poz\u00edci\u00f3ban egy tov\u00e1bbi karbonilcsoportot tartalmaz. A 7H-AI7O komponensek CO-veszt\u00e9sre \u00e9s [M+H-28]+ keletkez\u00e9s\u00e9re hajlamos reped\u00e9si tulajdons\u00e1gaival kombin\u00e1lva felt\u00e9telezhet\u0151, hogy a 7H-AI7O \u00e9s az AA komponensek k\u00f6z\u00f6tt biotranszform\u00e1ci\u00f3s kapcsolat \u00e1llhat fenn a n\u00f6v\u00e9nyekben. Ez\u00e9rt a j\u00f6v\u0151beli kutat\u00e1sok a 7H-AI7O \u00e9s az AA komponensek k\u00f6z\u00f6tti biotranszform\u00e1ci\u00f3s kapcsolatot is felt\u00e1rj\u00e1k az Acorus k\u00ednai gy\u00f3gy\u00e1szatban, valamint a talaj, az \u00e9ghajlat \u00e9s m\u00e1s t\u00e9nyez\u0151k hat\u00e1s\u00e1t a 7H-AI7O komponensek n\u00f6v\u00e9nyekben t\u00f6rt\u00e9n\u0151 bioszint\u00e9zis\u00e9re. K\u00eds\u00e9rleti bizony\u00edt\u00e9kot szolg\u00e1ltatni a hagyom\u00e1nyos k\u00ednai orvosl\u00e1s anyagi alapjainak tov\u00e1bbi felt\u00e1r\u00e1s\u00e1hoz az Acorus nemzets\u00e9gben a testny\u00edl\u00e1sok megnyit\u00e1s\u00e1ra, a v\u00e1lad\u00e9k elt\u00e1vol\u00edt\u00e1s\u00e1ra, az elme fel\u00e9breszt\u00e9s\u00e9re \u00e9s az intelligencia jav\u00edt\u00e1s\u00e1ra.<\/p>","protected":false},"excerpt":{"rendered":"

Analysis of the components of 7H-azulene [1,2,3-i, j] isoquinolin-7-one in Acorus genus traditional Chinese medicine based on UPLC-Q-TOF\/MS2 combination technology The APG IV system is the fourth edition of the angiosperm classification system established by the Angiosperm Phylogeny Group (APG). The classification system considers Acorales to be a branch of monocotyledonous plants in the middle […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nAnalysis of the components of 7H-azulene [1,2,3-i, j] isoquinolin-7-one in Acorus genus traditional Chinese medicine based on UPLC-Q-TOF\/MS2 combination technology - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/angiosperm-phylogeny-group\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Analysis of the components of 7H-azulene [1,2,3-i, j] isoquinolin-7-one in Acorus genus traditional Chinese medicine based on UPLC-Q-TOF\/MS2 combination technology - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Analysis of the components of 7H-azulene [1,2,3-i, j] isoquinolin-7-one in Acorus genus traditional Chinese medicine based on UPLC-Q-TOF\/MS2 combination technology The APG IV system is the fourth edition of the angiosperm classification system established by the Angiosperm Phylogeny Group (APG). 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