{"id":5191,"date":"2024-08-04T17:45:17","date_gmt":"2024-08-04T17:45:17","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5191"},"modified":"2024-08-04T17:45:17","modified_gmt":"2024-08-04T17:45:17","slug":"chaihu-and-baishao","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/chaihu-es-baishao\/","title":{"rendered":"HS-SPME-GC-MS elemz\u00e9s a Chaihu \u00e9s a Baishao ill\u00e9kony \u00f6sszetev\u0151inek v\u00e1ltoz\u00e1s\u00e1r\u00f3l a kompatibilit\u00e1s el\u0151tt \u00e9s ut\u00e1n"},"content":{"rendered":"<p>HS-SPME-GC-MS elemz\u00e9s a Chaihu \u00e9s a Baishao ill\u00e9kony \u00f6sszetev\u0151inek v\u00e1ltoz\u00e1s\u00e1r\u00f3l a kompatibilit\u00e1s el\u0151tt \u00e9s ut\u00e1n<br \/>\nA hagyom\u00e1nyos k\u00ednai gy\u00f3gyszerk\u00e9sz\u00edtm\u00e9ny p\u00e1rok a v\u00e9nyk\u00f6teles gy\u00f3gyszerek legkisebb egys\u00e9gei, \u00e9s a gy\u00f3gyszerp\u00e1rok kompatibilit\u00e1sa f\u0151k\u00e9nt az azonos qi keres\u00e9s\u00e9nek, egym\u00e1s kieg\u00e9sz\u00edt\u00e9s\u00e9nek, egym\u00e1s ellent\u00e9t\u00e9nek \u00e9s az azonos rendszer haszn\u00e1lat\u00e1nak szab\u00e1lyait k\u00f6veti. A feh\u00e9r bazsar\u00f3zsa t\u00e1pl\u00e1lja \u00e9s l\u00e1gy\u00edtja a m\u00e1jat, m\u00edg a Chaihu nyugtatja a m\u00e1jat \u00e9s enyh\u00edti a depresszi\u00f3t. A k\u00e9t gy\u00f3gyn\u00f6v\u00e9ny kombin\u00e1ci\u00f3ja el\u0151seg\u00edti a m\u00e1j qi fejl\u0151d\u00e9s\u00e9t, t\u00e1pl\u00e1lja a v\u00e9rt \u00e9s l\u00e1gy\u00edtja a m\u00e1jat. A feh\u00e9r bazsar\u00f3zsa \u00e9s a Chaihu kieg\u00e9sz\u00edtik egym\u00e1st, \u00e9s egym\u00e1st kieg\u00e9sz\u00edt\u0151 kapcsolatban \u00e1llnak. A feh\u00e9r p\u00fcnk\u00f6sdi r\u00f3zsa t\u00e1pl\u00e1lja a v\u00e9rt, megakad\u00e1lyozva, hogy a Chaihu t\u00fals\u00e1gosan sz\u00e9tsz\u00f3r\u00f3djon \u00e9s k\u00e1ros\u00edtsa a m\u00e1j yinj\u00e9t. A Chaihu por megakad\u00e1lyozza, hogy a feh\u00e9r p\u00fcnk\u00f6sdi r\u00f3zsa savany\u00fav\u00e1 \u00e9s hidegg\u00e9 v\u00e1ljon, \u00e9s a m\u00e1j qi stagn\u00e1ljon. Mind a m\u00e1j nyugtat\u00e1sa, mind a depresszi\u00f3 enyh\u00edt\u00e9se k\u00f6lcs\u00f6n\u00f6s seg\u00edts\u00e9get ig\u00e9nyel, kieg\u00e9sz\u00edtve egym\u00e1s er\u0151ss\u00e9geit \u00e9s gyenges\u00e9geit. A k\u00e9t gy\u00f3gyszert olyan formul\u00e1khoz kombin\u00e1lj\u00e1k, mint a Xiaoyao San, Sini San, Dachaihu Tang, Chaihu Shugan San, stb. A Bupleurum chinense a Bupleurum chinense DC. vagy Bupleurum scorzonerifolium Willd. erny\u0151f\u00e9l\u00e9k csal\u00e1dj\u00e1ba tartoz\u00f3 n\u00f6v\u00e9ny sz\u00e1r\u00edtott gy\u00f6kere. A feh\u00e9r p\u00fcnk\u00f6sdi r\u00f3zsa a Ranunculaceae csal\u00e1dba tartoz\u00f3 Paeonia lactiflora Pall. sz\u00e1r\u00edtott gy\u00f6kere. A vonatkoz\u00f3 szakirodalom \u00e1ttekint\u00e9se sor\u00e1n meg\u00e1llap\u00edtott\u00e1k, hogy kor\u00e1bbi tanulm\u00e1nyok g\u00e1zkromatogr\u00e1fia-t\u00f6megspektrometri\u00e1t (GC-MS) haszn\u00e1ltak a Bupleurum chinense \u00e9s a Paeonia lactiflora ill\u00e9kony \u00f6sszetev\u0151inek elemz\u00e9s\u00e9re. Mindeddig azonban nem sz\u00e1moltak be a g\u00e1zkromatogr\u00e1fia-t\u00f6megspektrometri\u00e1val (GC-MS) kombin\u00e1lt szil\u00e1rd f\u00e1zis\u00fa fejt\u00e9r-mikroextrakci\u00f3 (HS-SPME) alkalmaz\u00e1s\u00e1r\u00f3l a Bupleurum chinense \u00e9s a Paeonia lactiflora ill\u00e9kony \u00f6sszetev\u0151inek a kompatibilit\u00e1s el\u0151tt \u00e9s ut\u00e1n t\u00f6rt\u00e9n\u0151 elemz\u00e9s\u00e9re. A HS-SPME-t sz\u00e9les k\u00f6rben haszn\u00e1lj\u00e1k, \u00e9s jellemz\u0151i a nagy hat\u00e9konys\u00e1g \u00e9s a k\u00e9nyelem. Ez a tanulm\u00e1ny a HS-SPME-GC-MS technol\u00f3gi\u00e1t alkalmazta, kombin\u00e1lva a f\u0151komponens-elemz\u00e9ssel (PCA) \u00e9s m\u00e1s adatelemz\u00e9si m\u00f3dszerekkel, hogy megvizsg\u00e1lja a Chaihu \u00e9s a Baishao ill\u00e9kony komponenseit \u00e9s azok v\u00e1ltoz\u00e1sait a kompatibilit\u00e1s el\u0151tt \u00e9s ut\u00e1n, referenci\u00e1t ny\u00fajtva a gy\u00f3gyszer kompatibilit\u00e1si mechanizmus\u00e1nak tov\u00e1bbi felt\u00e1r\u00e1s\u00e1hoz.<\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5192\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-125.png\" alt=\"\" width=\"785\" height=\"376\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-125.png 785w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-125-768x368.png 768w\" sizes=\"(max-width: 785px) 100vw, 785px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5193\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-111.png\" alt=\"\" width=\"784\" height=\"776\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-111.png 784w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-111-768x760.png 768w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-111-727x720.png 727w\" sizes=\"(max-width: 784px) 100vw, 784px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5194\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-105.png\" alt=\"\" width=\"786\" height=\"776\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-105.png 786w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-105-768x758.png 768w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-105-729x720.png 729w\" sizes=\"(max-width: 786px) 100vw, 786px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5195\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-94.png\" alt=\"\" width=\"784\" height=\"516\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-94.png 784w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-94-768x505.png 768w\" sizes=\"(max-width: 784px) 100vw, 784px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5196\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-86.png\" alt=\"\" width=\"358\" height=\"281\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5197\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-79.png\" alt=\"\" width=\"779\" height=\"289\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-79.png 779w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-79-768x285.png 768w\" sizes=\"(max-width: 779px) 100vw, 779px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5198\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-71.png\" alt=\"\" width=\"773\" height=\"144\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-71.png 773w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-71-768x143.png 768w\" sizes=\"(max-width: 773px) 100vw, 773px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5199\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-66.png\" alt=\"\" width=\"779\" height=\"312\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-66.png 779w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-66-768x308.png 768w\" sizes=\"(max-width: 779px) 100vw, 779px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5200\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-60.png\" alt=\"\" width=\"777\" height=\"151\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-60.png 777w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-60-768x149.png 768w\" sizes=\"(max-width: 777px) 100vw, 777px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5201\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-2.jpg\" alt=\"\" width=\"707\" height=\"262\" \/><br \/>\nEz a tanulm\u00e1ny HS-SPME-GC-MS m\u00f3dszert alkalmazott a Chaihu, Paeonia lactiflora \u00e9s Chaihu Paeonia lactiflora gy\u00f3gyn\u00f6v\u00e9nyp\u00e1rok ill\u00e9kony \u00f6sszetev\u0151inek meghat\u00e1roz\u00e1s\u00e1ra \u00e9s elemz\u00e9s\u00e9re. A Chaihu Paeonia lactiflora 16 egyedi ill\u00e9kony komponenssel, a Chaihu-val 27 k\u00f6z\u00f6s ill\u00e9kony komponenssel, a Paeonia lactiflor\u00e1val pedig 7 k\u00f6z\u00f6s ill\u00e9kony komponenssel rendelkezik.<\/p>\n<p>A gy\u00f3gyn\u00f6v\u00e9ny ill\u00e9kony komponens-tartalm\u00e1t \u00f6sszehasonl\u00edtva egy egyszer\u0171 gy\u00f3gyn\u00f6v\u00e9ny\u00e9vel, meg\u00e1llap\u00edthat\u00f3, hogy a gy\u00f3gyn\u00f6v\u00e9nyben 15 olyan komponens van, amelynek ill\u00e9kony komponens-tartalma megn\u00f6vekedett egy egyszer\u0171 gy\u00f3gyn\u00f6v\u00e9nyhez k\u00e9pest, bele\u00e9rtve az \u03b1 - kurkum\u00e1t, \u03b2 - mirh\u00e1t, oxid\u00e1lt karyophyllen, szoforid, (+) - \u03b2 - ciprus terp\u00e9nek stb. A gy\u00f3gyszerben 15 olyan komponens van, amelynek az ill\u00e9kony komponensek tartalma alacsonyabb az egyes gy\u00f3gyn\u00f6v\u00e9nyekhez k\u00e9pest, bele\u00e9rtve a dodek\u00e1nt, a benzil-alkoholt, a hexadec\u00e1nt, a nonadec\u00e1nt stb. Ugyanakkor 16 \u00faj ill\u00e9kony vegy\u00fcletet adtak hozz\u00e1 a gy\u00f3gyszerhez, bele\u00e9rtve a verbenont, a transz-karyophil\u00e9nt, az \u03b1 - kumarint, a valenc\u00e9nt, a prosztaglandin E1-et stb. Az egyes gy\u00f3gyn\u00f6v\u00e9nyekkel \u00f6sszehasonl\u00edtva a (+) - \u03b2 - ciprus terp\u00e9nek megn\u00f6vekedett tartalma a gy\u00f3gyn\u00f6v\u00e9nyben a Platycodon grandiflorus ill\u00f3olaj f\u0151 \u00f6sszetev\u0151je, amely antibakteri\u00e1lis, gyullad\u00e1scs\u00f6kkent\u0151, \u00f6sszeh\u00faz\u00f3, vizelethajt\u00f3, l\u00e1gy\u00edt\u00f3, k\u00f6ptet\u0151 \u00e9s gomba\u00f6l\u0151 hat\u00e1s\u00fa; \u03b1 - A kurkumin er\u0151s antibakteri\u00e1lis hat\u00e1s\u00fa; \u03b2 - a mirrhen sz\u00e1mos mellr\u00e1ksejtet k\u00e9pes g\u00e1tolni; Az oxid\u00e1lt karyophyllen asztmaellenes, daganatellenes, antibakteri\u00e1lis \u00e9s k\u00f6h\u00f6g\u00e9scsillap\u00edt\u00f3 hat\u00e1s\u00fa. Tov\u00e1bb\u00e1, a k\u00e9t hat\u00f3anyag kombin\u00e1ci\u00f3ja ut\u00e1n \u00fajonnan hozz\u00e1adott komponensek, mint a transz-karyophil\u00e9n, az alfa-b\u00e9taolaj, a prosztaglandin E1 stb., a transz-karyophil\u00e9n bizonyos asztmaellenes \u00e9s antibakteri\u00e1lis hat\u00e1sokkal rendelkezik, m\u00edg az el\u0151\u00e1ll\u00edtott alfa-b\u00e9taolaj j\u00f3 antibakteri\u00e1lis hat\u00e1ssal rendelkezik. A prosztaglandin E1 j\u00f3 gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1ssal rendelkezik, ami \u00f6sszhangban van a Chaihu Baishao kombin\u00e1ci\u00f3 klinikai alkalmaz\u00e1s\u00e1val. Ezenk\u00edv\u00fcl a gy\u00f3gyszer alacsony toxicit\u00e1ssal rendelkezik a cs\u00f6kkentett tartalm\u00fa \u00f6sszetev\u0151kre, mint p\u00e9ld\u00e1ul a dodek\u00e1n; A benzil-alkohol m\u00e9rgez\u0151 a k\u00f6zponti idegrendszerre; A hexadec\u00e1n g\u0151z irrit\u00e1ci\u00f3t okozhat az emberi test fels\u0151 l\u00e9gutak, a szem \u00e9s a b\u0151r irrit\u00e1ci\u00f3j\u00e1ra, \u00e9s ezeknek a k\u00e1ros \u00f6sszetev\u0151knek a tartalma cs\u00f6kken a k\u00e9t gy\u00f3gyszer kombin\u00e1ci\u00f3ja ut\u00e1n. Az ill\u00e9kony komponensek szempontj\u00e1b\u00f3l meg\u00e1llap\u00edthat\u00f3, hogy a Chaihu \u00e9s a Baishao kombin\u00e1ci\u00f3ja cs\u00f6kkenti a toxicit\u00e1st \u00e9s n\u00f6veli a hat\u00e9konys\u00e1got. P\u00e9ld\u00e1ul a klasszikus k\u00ednai gy\u00f3gy\u00e1szati k\u00e9sz\u00edtm\u00e9ny, az Anru Xiaotong Wan, amelynek f\u0151 \u00f6sszetev\u0151i a Chaihu \u00e9s a Baishao, egy\u00fcttesen alkalmazva nemcsak a m\u00e1jat nyugtatja \u00e9s enyh\u00edti a depresszi\u00f3t a m\u00e1jprobl\u00e9m\u00e1k kezel\u00e9s\u00e9re, hanem a m\u00e1jat is l\u00e1gy\u00edtja \u00e9s t\u00e1pl\u00e1lja a jint a m\u00e1jtest kieg\u00e9sz\u00edt\u00e9s\u00e9re. Hat\u00e1s\u00e1ra t\u00e1pl\u00e1lja a v\u00e9rt, t\u00e1pl\u00e1lja a jint \u00e9s enyh\u00edti a f\u00e1jdalmat.<\/p>\n<p>Egy tanulm\u00e1ny Soxhlet, mikrohull\u00e1m\u00fa, v\u00edzdesztill\u00e1ci\u00f3s \u00e9s szuperkritikus CO2-g\u0151zdesztill\u00e1ci\u00f3s extrakci\u00f3s m\u00f3dszereket alkalmazott a Bupleurum chinense ill\u00f3olaj\u00e1nak kivon\u00e1s\u00e1ra \u00e9s k\u00e9miai \u00f6sszetev\u0151inek min\u0151s\u00e9gi azonos\u00edt\u00e1s\u00e1ra. Az elemz\u00e9s sor\u00e1n \u00f6sszesen 34, 21, 25 \u00e9s 19 ill\u00e9kony komponenst azonos\u00edtottak. Ebben a tanulm\u00e1nyban a HS-SPME-t haszn\u00e1lt\u00e1k a Bupleurum chinense 61 ill\u00e9kony komponens\u00e9nek elk\u00fcl\u00f6n\u00edt\u00e9s\u00e9re \u00e9s min\u0151s\u00e9gi azonos\u00edt\u00e1s\u00e1ra. A HS-SPME-GC-MS kombin\u00e1lt technol\u00f3gia alkalmaz\u00e1sa jav\u00edthatja a gy\u00f3gyszerek ill\u00e9kony \u00f6sszetev\u0151inek extrakci\u00f3s ar\u00e1ny\u00e1t. Az irodalomban haszn\u00e1lt m\u00f3dszerekkel \u00f6sszehasonl\u00edtva a cs\u00facsok sz\u00e1ma \u00e9s a drogok ill\u00e9kony anyagtartalma magasabb, ami azt jelzi, hogy a headspace szil\u00e1rd f\u00e1zis\u00fa mikroextrakci\u00f3 nagy hat\u00e9konys\u00e1ggal \u00e9s \u00e9rz\u00e9kenys\u00e9ggel rendelkezik a drogok ill\u00e9kony \u00f6sszetev\u0151inek extrakci\u00f3j\u00e1ban.<\/p>\n<p>\u00d6sszefoglalva, a Chaihu \u00e9s a Baishao kombin\u00e1ci\u00f3j\u00e1t sz\u00e9les k\u00f6rben haszn\u00e1lj\u00e1k a klinikai gyakorlatban. A Chaihu, a Baishao \u00e9s gy\u00f3gyszereik ill\u00e9kony \u00f6sszetev\u0151ir\u0151l azonban kev\u00e9s kutat\u00e1s k\u00e9sz\u00fclt. Ez a k\u00eds\u00e9rlet a HS-SPME-GC-MS technol\u00f3gi\u00e1t alkalmazta a Chaihu, a Baishao \u00e9s a Chaihu Baishao ill\u00e9kony \u00f6sszetev\u0151inek meghat\u00e1roz\u00e1s\u00e1ra. Az egyes komponensek sz\u00e1zal\u00e9kos tartalm\u00e1t a ter\u00fclet normaliz\u00e1l\u00e1si m\u00f3dszerrel hat\u00e1roztuk meg. Az ill\u00e9kony komponensek szempontj\u00e1b\u00f3l elemezt\u00e9k a Chaihu Baishao k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek v\u00e1ltoz\u00e1s\u00e1t a kompatibilit\u00e1s el\u0151tt \u00e9s ut\u00e1n. A kompatibilit\u00e1si szab\u00e1lyok alapj\u00e1n a Chaihu felt\u00e1r\u00e1sra ker\u00fclt? A Paeonia lactiflora gy\u00f3gyn\u00f6v\u00e9nyek kompatibilit\u00e1s\u00e1nak ter\u00e1pi\u00e1s mechanizmus\u00e1nak tov\u00e1bbi felt\u00e1r\u00e1sa.<\/p>","protected":false},"excerpt":{"rendered":"<p>HS-SPME-GC-MS analysis of changes in volatile components of Chaihu and Baishao before and after compatibility Traditional Chinese medicine pairs are the smallest unit of prescription medication, and the compatibility of drug pairs mainly follows the rules of seeking the same qi, complementing each other, opposing each other, and using the same system. White peony nourishes [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>HS-SPME-GC-MS analysis of changes in volatile components of Chaihu and Baishao before and after compatibility - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/chaihu-es-baishao\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HS-SPME-GC-MS analysis of changes in volatile components of Chaihu and Baishao before and after compatibility - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"HS-SPME-GC-MS analysis of changes in volatile components of Chaihu and Baishao before and after compatibility Traditional Chinese medicine pairs are the smallest unit of prescription medication, and the compatibility of drug pairs mainly follows the rules of seeking the same qi, complementing each other, opposing each other, and using the same system. 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