{"id":5066,"date":"2024-08-04T17:08:27","date_gmt":"2024-08-04T17:08:27","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5066"},"modified":"2024-08-04T17:08:27","modified_gmt":"2024-08-04T17:08:27","slug":"a-new-amide-alkaloid-in-the-root-of-fake-konjac","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/a-new-amide-alkaloid-in-the-root-of-fake-konjac\/","title":{"rendered":"Egy \u00faj amid-alkaloid a hamis konjak gy\u00f6ker\u00e9ben"},"content":{"rendered":"

Egy \u00faj amid-alkaloid a hamis konjak gy\u00f6ker\u00e9ben
\nA Piper sarmentosum a Piperaceae csal\u00e1dba tartoz\u00f3, \u00e9vel\u0151, k\u00fasz\u00f3, csom\u00f3pontr\u00f3l csom\u00f3pontra gy\u00f6kerez\u0151 gy\u00f3gyn\u00f6v\u00e9ny, amely \u00e1ltal\u00e1ban aljn\u00f6v\u00e9nyzetben vagy \u00fat menti vizes \u00e9l\u0151helyeken tal\u00e1lhat\u00f3. K\u00edn\u00e1ban f\u0151k\u00e9nt Yunnan, Fujian \u00e9s Guizhou tartom\u00e1nyokban termesztik, de elterjedt Indi\u00e1ban, Vietnamban, a F\u00fcl\u00f6p-szigeteken \u00e9s Malajzi\u00e1ban is. A hamis konjac nemcsak gazdag gy\u00f3gy\u00e1szati \u00e9rt\u00e9kkel b\u00edr, hanem magas d\u00edsz\u00edt\u0151, \u00e9tkez\u00e9si \u00e9s gazdas\u00e1gi \u00e9rt\u00e9kkel is. A klasszikusok, p\u00e9ld\u00e1ul a \"Chinese Materia Medica\" szerint a hamis konjac meleg term\u00e9szet\u0171, keser\u0171 \u00e9s cs\u00edp\u0151s \u00edz\u0171. Gy\u00f6kerei, levelei \u00e9s gy\u00fcm\u00f6lcsei mind gy\u00f3gyszerk\u00e9nt haszn\u00e1lhat\u00f3k, hat\u00e1suk a k\u00f6z\u00e9ps\u0151 meleg\u00edt\u00e9s \u00e9s a hideg eloszlat\u00e1sa, a sz\u00e9l \u00e9s a nedvess\u00e9g el\u0171z\u00e9se, a duzzanat \u00e9s a f\u00e1jdalom cs\u00f6kkent\u00e9se. Gyakran haszn\u00e1lj\u00e1k a gyomorf\u00e1jdalom, a reum\u00e1s h\u00e1tf\u00e1j\u00e1s, a terhess\u00e9gi \u00f6d\u00e9ma \u00e9s a traum\u00e1s v\u00e9rz\u00e9s kezel\u00e9s\u00e9ben, jelent\u0151s ter\u00e1pi\u00e1s hat\u00e1ssal. A hamis konjac leveleket sz\u00e9les k\u00f6rben haszn\u00e1lj\u00e1k \u00e9s termesztik f\u0171szerk\u00e9nt D\u00e9l-K\u00edna Jiangsu, Zhejiang \u00e9s Guangdong r\u00e9gi\u00f3iban, egyedi cs\u00edp\u0151s arom\u00e1juk miatt.
\nA modern farmakol\u00f3giai vizsg\u00e1latok kimutatt\u00e1k, hogy a hamis konjak kivonatok sz\u00e1mos biol\u00f3giai aktivit\u00e1ssal rendelkeznek, p\u00e9ld\u00e1ul antioxid\u00e1ns, gyullad\u00e1scs\u00f6kkent\u0151, antibakteri\u00e1lis, rovar\u00f6l\u0151, hipoglik\u00e9mi\u00e1s \u00e9s neuroprotekt\u00edv tulajdons\u00e1gokkal. Jelenleg a hamis konjak k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek kutat\u00e1sa mind hazai, mind nemzetk\u00f6zi szinten els\u0151sorban a levelekre \u00e9s a f\u00f6ld feletti r\u00e9szekre \u00f6sszpontos\u00edt, \u00e9s viszonylag kevesebb kutat\u00e1s foglalkozik a f\u00f6ld alatti gy\u00f6kerekkel. A hamis konjakb\u00f3l izol\u00e1lt \u00e9s azonos\u00edtott k\u00e9miai komponensek k\u00f6z\u00e9 tartoznak az alkaloidok, lign\u00e1nok, flavonoidok \u00e9s szterolok. Kutat\u00f3csoportunk a korai szakaszban 7 alkaloid vegy\u00fcletet izol\u00e1lt a hamis konjac levelekb\u0151l, amelyek k\u00f6z\u00fcl n\u00e9h\u00e1ny j\u00f3 antibakteri\u00e1lis aktivit\u00e1st mutatott a Staphylococcus aureus ellen. A hamis konjac k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek \u00e9s biol\u00f3giai aktivit\u00e1s\u00e1nak folyamatos kutat\u00e1sa sor\u00e1n meg\u00e1llap\u00edtottuk, hogy a hamis konjac gy\u00f6k\u00e9r 95% etanolos kivonata k\u00e9pes enyh\u00edteni a karrag\u00e9n \u00e1ltal kiv\u00e1ltott eg\u00e9rl\u00e1b duzzanat t\u00fcneteit, \u00e9s d\u00f3zisf\u00fcgg\u0151 hat\u00e1ssal rendelkezik. Ez\u00e9rt felt\u00e9telezhet\u0151, hogy a kivonat gyullad\u00e1scs\u00f6kkent\u0151 hat\u00f3anyagokat tartalmaz. Kapcsol\u00f3d\u00f3 vizsg\u00e1latok kimutatt\u00e1k, hogy az alkaloidok a f\u0151 hat\u00f3anyagok a hamis konjac gy\u00f6ker\u00e9ben. Ebben a k\u00eds\u00e9rletben a hamis konjac gy\u00f6k\u00e9r 95% etanolos kivonat\u00e1nak k\u00e9miai \u00f6sszet\u00e9tel\u00e9t vizsg\u00e1ltuk, \u00e9s az LPS \u00e1ltal induk\u00e1lt RAW264.7 in vitro sejtgyullad\u00e1sos modellt haszn\u00e1ltuk a kapott monomer vegy\u00fcletek gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1s\u00e1nak sz\u0171r\u00e9s\u00e9re. A c\u00e9l a hamis konjac gy\u00f6k\u00e9r k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek \u00e9s a kapcsol\u00f3d\u00f3 farmakol\u00f3giai anyagoknak a tiszt\u00e1z\u00e1sa, hogy t\u00e1mpontot ny\u00fajtson a hamis konjac n\u00f6v\u00e9nyi er\u0151forr\u00e1sok tov\u00e1bbi racion\u00e1lis fejleszt\u00e9s\u00e9hez \u00e9s felhaszn\u00e1l\u00e1s\u00e1hoz.<\/p>\n

\"\"\"\"\"\"
\nEz a k\u00eds\u00e9rlet modern kromatogr\u00e1fi\u00e1s elv\u00e1laszt\u00e1si technik\u00e1kat \u00e9s spektroszk\u00f3piai m\u00f3dszereket alkalmazott 10 alkaloid vegy\u00fclet izol\u00e1l\u00e1s\u00e1ra \u00e9s azonos\u00edt\u00e1s\u00e1ra a hamis konjak gy\u00f6ker\u00e9b\u0151l. K\u00f6z\u00fcl\u00fck az 1. vegy\u00fclet egy \u00faj amid-alkaloid, \u00e9s az 5. vegy\u00fclet kiv\u00e9tel\u00e9vel minden vegy\u00fcletet el\u0151sz\u00f6r izol\u00e1ltak ebb\u0151l a n\u00f6v\u00e9nyb\u0151l. Az izol\u00e1lt vegy\u00fcletek gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1s\u00e1t LPS stimul\u00e1lt RAW264.7 makrof\u00e1g gyullad\u00e1sos modell seg\u00edts\u00e9g\u00e9vel vizsg\u00e1ltuk. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy az 1., 2., 4. \u00e9s 10. vegy\u00fclet g\u00e1tl\u00f3 hat\u00e1ssal volt az NO-termel\u00e9sre, \u00e9s nem mutatott jelent\u0151s citotoxicit\u00e1st a vizsg\u00e1lt koncentr\u00e1ci\u00f3kban. E tanulm\u00e1ny eredm\u00e9nyei tov\u00e1bb gazdag\u00edtj\u00e1k a hamis konjac gy\u00f6k\u00e9r k\u00e9miai \u00f6sszet\u00e9tel\u00e9t, \u00e9s el\u0151zetesen tiszt\u00e1zz\u00e1k a hamis konjac gy\u00f6k\u00e9rben l\u00e9v\u0151 egyes gyullad\u00e1scs\u00f6kkent\u0151 hat\u00f3anyagok alapjait, bizonyos referenci\u00e1t \u00e9s elm\u00e9leti alapot biztos\u00edtva e n\u00f6v\u00e9nyi er\u0151forr\u00e1s j\u00f6v\u0151beli fejleszt\u00e9s\u00e9hez \u00e9s felhaszn\u00e1l\u00e1s\u00e1hoz.<\/p>","protected":false},"excerpt":{"rendered":"

A new amide alkaloid in the root of fake konjac Piper sarmentosum is a perennial, creeping, node by node rooted herb of the Piperaceae family, commonly found in understory or roadside wetlands. It is mainly produced in provinces such as Yunnan, Fujian, and Guizhou in China, and is also distributed in India, Vietnam, the Philippines, […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nA new amide alkaloid in the root of fake konjac - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/a-new-amide-alkaloid-in-the-root-of-fake-konjac\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A new amide alkaloid in the root of fake konjac - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"A new amide alkaloid in the root of fake konjac Piper sarmentosum is a perennial, creeping, node by node rooted herb of the Piperaceae family, commonly found in understory or roadside wetlands. 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