{"id":5003,"date":"2024-08-04T16:48:23","date_gmt":"2024-08-04T16:48:23","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5003"},"modified":"2024-08-04T16:48:23","modified_gmt":"2024-08-04T16:48:23","slug":"ground-beetle-sinensis","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/ground-beetle-sinensis\/","title":{"rendered":"A sinensis f\u00f6ldi bog\u00e1r azonos\u00edt\u00e1sa \u00e9s el\u0151\u00e1ll\u00edt\u00e1sa jellemz\u0151 ionok alapj\u00e1n"},"content":{"rendered":"

A sinensis f\u00f6ldi bog\u00e1r azonos\u00edt\u00e1sa \u00e9s el\u0151\u00e1ll\u00edt\u00e1sa jellemz\u0151 ionok alapj\u00e1n
\nA f\u00f6ldi bog\u00e1rf\u00e9reg el\u0151sz\u00f6r a Shennong's Classic of Materia Medica c\u00edm\u0171 m\u0171v\u00e9ben jelent meg, \u00e9s a k\u00f6z\u00e9pfok\u00faak k\u00f6z\u00e9 sorolt\u00e1k. A Ground beetle sinensis Walker vagy Steleophaga plancyi (Boleny) az Eupolyphaga sinensis Walker vagy Steleophaga plancyi sz\u00e1r\u00edtott n\u0151i teste. Az \u0151r\u00f6lt bog\u00e1rbog\u00e1r els\u0151sorban aminosavakat, feh\u00e9rj\u00e9ket, ill\u00f3olaj-vegy\u00fcleteket \u00e9s egy\u00e9b \u00f6sszetev\u0151ket, p\u00e9ld\u00e1ul alkaloidokat, zs\u00edrsavakat, fibrinolitikus hat\u00f3anyagokat \u00e9s nyomelemeket tartalmaz. A f\u00f6ldi bog\u00e1rbog\u00e1r hat\u00e1s\u00e1ra sz\u00e9toszlatja a v\u00e9r pang\u00e1s\u00e1t, megsz\u00fcnteti a szil\u00e1rd csom\u00f3t, a f\u00fcst\u00f6l\u00e9st \u00e9s a f\u00e1jdalmat, cs\u00f6kkenti a mellet \u00e9s megnyitja a csatorn\u00e1kat stb. Z\u00faz\u00f3d\u00e1sok \u00e9s s\u00e9r\u00fcl\u00e9sek, \u00edns\u00e9r\u00fcl\u00e9sek \u00e9s t\u00f6r\u00e9sek, v\u00e9r pang\u00e1s \u00e9s amenorrea, sz\u00fcl\u00e9s ut\u00e1ni v\u00e9r pang\u00e1s \u00e9s hasi f\u00e1jdalom, jelek \u00e9s duzzanat eset\u00e9n alkalmazhat\u00f3. A modern farmakol\u00f3giai kutat\u00e1sok azt mutatj\u00e1k, hogy a f\u00f6ldi bog\u00e1ncsnak v\u00e9ralvad\u00e1sg\u00e1tl\u00f3, daganatellenes, v\u00e9rzs\u00edr-szab\u00e1lyoz\u00f3, f\u00e1jdalomcsillap\u00edt\u00f3, gyullad\u00e1scs\u00f6kkent\u0151 \u00e9s bakt\u00e9rium\u00f6l\u0151 hat\u00e1sa van, s\u0151t \"az els\u0151 v\u00e9r\u00e1raml\u00e1st szab\u00e1lyoz\u00f3 gy\u00f3gyszernek\" is nevezik. A klinikai gyakorlatban sz\u00e9les k\u00f6rben alkalmazz\u00e1k (a Yaozhinet adatb\u00e1zis\u00e1nak statisztik\u00e1i szerint 151 hagyom\u00e1nyos k\u00ednai szabadalmi gy\u00f3gyszert \u00e9s egyszer\u0171 k\u00e9sz\u00edtm\u00e9nyt tartalmaz\u00f3 receptet gy\u0171jt\u00f6ttek \u00f6ssze, amelyek \u0151r\u00f6lt bog\u00e1rbogarat tartalmaznak), \u00e9s az adagol\u00e1s is nagy. Jelenleg k\u00e9tf\u00e9le \u0151r\u00f6lt bog\u00e1rbog\u00e1r van forgalomban: vadon \u00e9l\u0151 \u00e9s mesters\u00e9gesen teny\u00e9sztett. Mivel azonban a vadon \u00e9l\u0151 f\u00f6ldi bog\u00e1rbogarak sz\u00e1ma \u00e9vr\u0151l \u00e9vre cs\u00f6kken, a mesters\u00e9gesen nevelt term\u00e9kek nagy ar\u00e1nyt k\u00e9pviselnek a klinikai alkalmaz\u00e1sban, \u00e9s a mesters\u00e9ges hamis\u00edt\u00e1s \u00e9s szennyez\u0151d\u00e9s viselked\u00e9se id\u0151r\u0151l id\u0151re el\u0151fordul, ami csak a jellemz\u0151ik azonos\u00edt\u00e1s\u00e1val vezethet t\u00e9ves meg\u00edt\u00e9l\u00e9shez. \u00d6sszess\u00e9g\u00e9ben a K\u00ednai Gy\u00f3gyszerk\u00f6nyv 2020-as kiad\u00e1s\u00e1ban a f\u00f6ldi bog\u00e1rf\u00e9reg alatt szerepl\u0151 vizsg\u00e1lati t\u00e9telek viszonylag egyszer\u0171ek, amelyek nem k\u00e9pesek \u00e1tfog\u00f3an \u00e9s pontosan t\u00fckr\u00f6zni a f\u00f6ldi bog\u00e1rf\u00e9reg hiteless\u00e9g\u00e9t \u00e9s min\u0151s\u00e9g\u00e9t.<\/p>\n

A f\u00f6ldi bog\u00e1rbog\u00e1r els\u0151sorban aminosavakat, feh\u00e9rj\u00e9ket, ill\u00f3olaj-vegy\u00fcleteket stb. tartalmaz. Ebben a szakaszban a min\u0151s\u00e9ggel kapcsolatos kutat\u00e1sai is ezekre az \u00f6sszetev\u0151kre \u00f6sszpontos\u00edtanak. Az ut\u00f3bbi \u00e9vekben n\u00e9h\u00e1ny tud\u00f3s molekul\u00e1ris farmakogn\u00f3ziai m\u00f3dszereket is alkalmazott a f\u00f6ldi bog\u00e1rbog\u00e1r eredetis\u00e9g\u00e9nek vizsg\u00e1lat\u00e1ra. P\u00e9ld\u00e1ul Chen et al. az eupolyphaga bogarak \u00e9s a hamis\u00edtott Phnom Penh-i f\u00f6ldi bog\u00e1r kromatogr\u00e1fi\u00e1s \u00e9s molekul\u00e1ris biol\u00f3giai m\u00f3dszerrel t\u00f6rt\u00e9n\u0151 azonos\u00edt\u00e1s\u00e1nak m\u00f3dszer\u00e9t is l\u00e9trehozta. A DNS-vonalk\u00f3dok adatb\u00e1zissal val\u00f3 \u00f6sszehasonl\u00edt\u00e1sa ut\u00e1n megadhat\u00f3 a legk\u00f6zelebbi faj szekvenci\u00e1ja \u00e9s annak \u00f6sszehasonl\u00edt\u00e1sa, ami egy\u00e9rtelm\u0171en meghat\u00e1rozhatja a fajt\u00e1k forr\u00e1s\u00e1t; Lu et al. poliakrilamid g\u00e9lelektrofor\u00e9zist haszn\u00e1lt h\u00e1romf\u00e9le f\u00f6ldi bog\u00e1r bog\u00e1r feh\u00e9rj\u00e9inek azonos\u00edt\u00e1s\u00e1ra, valamint az azonos \u00e9s k\u00fcl\u00f6nb\u00f6z\u0151 helyekr\u0151l sz\u00e1rmaz\u00f3 bogarak\u00e9ra. A m\u00f3dszer nagy felbont\u00f3k\u00e9pess\u00e9ggel \u00e9s j\u00f3 reproduk\u00e1lhat\u00f3s\u00e1ggal rendelkezik. A molekul\u00e1ris farmakogn\u00f3ziai technol\u00f3gi\u00e1nak azonban magas laborat\u00f3riumi k\u00f6vetelm\u00e9nyei vannak, \u00e9s nehezen n\u00e9pszer\u0171s\u00edthet\u0151, bizonyos korl\u00e1toz\u00e1sokkal j\u00e1r. A K\u00ednai N\u00e9pk\u00f6zt\u00e1rsas\u00e1g gy\u00f3gyszerk\u00f6nyv\u00e9ben (2020-as kiad\u00e1s) (a tov\u00e1bbiakban: K\u00ednai Gy\u00f3gyszerk\u00f6nyv) a f\u00f6ldi bog\u00e1r sinensis gy\u00f3gy\u00e1szati anyagok azonos\u00edt\u00e1sa alatt csak mikroszk\u00f3pos azonos\u00edt\u00e1s \u00e9s v\u00e9konyr\u00e9teg-azonos\u00edt\u00e1s szerepel, \u00e9s ez a m\u00f3dszer csak a nyersanyagok azonos\u00edt\u00e1s\u00e1ra alkalmazhat\u00f3. A kivont \u0151r\u00f6lt bog\u00e1r sinensis \u00e9s az \u0151r\u00f6lt bog\u00e1r sinensis-t tartalmaz\u00f3 k\u00e9sz\u00edtm\u00e9nyeket a m\u00f3dszer rosszul \u00e1tvihet\u0151 \u00e9s nem lehet hat\u00e9konyan megk\u00fcl\u00f6nb\u00f6ztetni.
\nA faji k\u00fcl\u00f6nbs\u00e9gekkel rendelkez\u0151 biomarkerk\u00e9nt a jellegzetes peptidek egyre ink\u00e1bb kiforrott\u00e1 v\u00e1lnak az \u00e1llatgy\u00f3gy\u00e1szati kutat\u00e1sokban. Egyes tud\u00f3sok a tekn\u0151s A, antilop szarv, szam\u00e1rb\u0151r ragaszt\u00f3, szarvas szarvas szarv gumi, sz\u00e1zl\u00e1b\u00fa, szarvas szarv stb. kutat\u00e1s\u00e1t a jellegzetes peptid technol\u00f3gi\u00e1n kereszt\u00fcl val\u00f3s\u00edtott\u00e1k meg. A j\u00f3 specificit\u00e1s \u00e9s az egyszer\u0171 m\u0171k\u00f6d\u00e9s jellemz\u0151i megk\u00f6nny\u00edtik a mindennapi ellen\u0151rz\u00e9sben val\u00f3 el\u0151mozd\u00edt\u00e1s\u00e1t. A t\u00f6megspektrometri\u00e1s detekt\u00e1l\u00e1son alapul\u00f3 karakterisztikus peptidtechnol\u00f3gia egyszerre t\u00f6bb fajra jellemz\u0151 peptidion-inform\u00e1ci\u00f3t is be\u00e1ll\u00edthat detekt\u00e1l\u00e1si indik\u00e1tork\u00e9nt, ami v\u00e1rhat\u00f3an lehet\u0151v\u00e9 teszi a hiteless\u00e9g azonos\u00edt\u00e1s\u00e1t, mik\u00f6zben a hamis\u00edtott \u00f6sszetev\u0151k tov\u00e1bbi pontos meghat\u00e1roz\u00e1s\u00e1t \u00e9s a hamis\u00edtott \u00f6sszetev\u0151k relat\u00edv mennyis\u00e9gi meghat\u00e1roz\u00e1s\u00e1t. Sz\u00e9lesk\u00f6r\u0171 \u00e9s f\u00e9nyes alkalmaz\u00e1si kil\u00e1t\u00e1sokkal rendelkezik. Az ionp\u00e1r-meghat\u00e1roz\u00e1s beker\u00fclt a K\u00ednai Gy\u00f3gyszerk\u00f6nyvbe (2020) a szam\u00e1rb\u0151r-, agancs- \u00e9s tekn\u0151sb\u0151r-ragaszt\u00f3 azonos\u00edt\u00e1si t\u00e9telek k\u00f6z\u00e9. A jellegzetes peptidek min\u0151s\u00e9gjelz\u0151k\u00e9nt val\u00f3 megjelen\u00e9se K\u00edna hivatalos jogi k\u00f3dex\u00e9ben v\u00e9get vetett annak a helyzetnek, hogy az \u00e1llati eredet\u0171 gy\u00f3gyszerek nem rendelkeznek a jogi el\u0151\u00edr\u00e1sokban meghat\u00e1rozott min\u0151s\u00e9gellen\u0151rz\u00e9si \u00f6sszetev\u0151kkel. A kivonat t\u00f6bbnyire vizet haszn\u00e1l old\u00f3szerk\u00e9nt. Miut\u00e1n az \u00e1llati drogokat, mint p\u00e9ld\u00e1ul az \u0151r\u00f6lt bog\u00e1ncsbog\u00e1r, kioldj\u00e1k \u00e9s felforralj\u00e1k, a kollag\u00e9n nem specifikus leboml\u00e1son megy kereszt\u00fcl, \u00e9s v\u00edzben old\u00f3d\u00f3 peptideket k\u00e9pez. Egyes peptidek a biofilmeken kereszt\u00fcl felsz\u00edv\u00f3dhatnak a v\u00e9rbe, hogy k\u00fcl\u00f6nb\u00f6z\u0151 biol\u00f3giai hat\u00e1sokat j\u00e1tszanak. Azonban nincs jelent\u00e9s a f\u00f6ldi bog\u00e1r sinensis azonos\u00edt\u00e1s\u00e1r\u00f3l \u00e9s annak jellegzetes ionokkal t\u00f6rt\u00e9n\u0151 el\u0151\u00e1ll\u00edt\u00e1s\u00e1r\u00f3l itthon \u00e9s k\u00fclf\u00f6ld\u00f6n. Ebben a tanulm\u00e1nyban a fenti jellegzetes ionok azonos\u00edt\u00e1si technol\u00f3gi\u00e1j\u00e1t referenciak\u00e9nt haszn\u00e1lva alkalmazt\u00e1k a f\u00f6ldi bog\u00e1rbogarak hiteless\u00e9g\u00e9nek azonos\u00edt\u00e1s\u00e1ra, referenci\u00e1t biztos\u00edtva a f\u00f6ldi bog\u00e1rbogarak \u00e9s k\u00e9sz\u00edtm\u00e9nyeik min\u0151s\u00e9gi kutat\u00e1s\u00e1hoz.<\/p>\n

\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"
\nA ground beetle sinensis bizony\u00edtottan hat\u00e9kony k\u00fcl\u00f6nb\u00f6z\u0151 betegs\u00e9gek, p\u00e9ld\u00e1ul a r\u00e1k, a tromb\u00f3zis g\u00e1tl\u00e1sa, az immunit\u00e1s fokoz\u00e1sa \u00e9s a combfej avaszkul\u00e1ris nekr\u00f3zis\u00e1nak kezel\u00e9s\u00e9re. A k\u00f6zelm\u00faltban jelentett\u00e9k, hogy a f\u00f6ldi bog\u00e1rbog\u00e1r, a pi\u00f3ca \u00e9s a sz\u00e1zl\u00e1b\u00fa nyilv\u00e1nval\u00f3 klinikai hat\u00e9konys\u00e1got mutatott endometritiszben. Neh\u00e9z azonban a f\u00f6ldi bog\u00e1rbogarat \u00e9s a f\u00f6ldi bogarat tartalmaz\u00f3 recepteket helyesen azonos\u00edtani. Jelenleg az \u00e1llati gy\u00f3gyszerek min\u0151s\u00e9gvizsg\u00e1lata els\u0151sorban olyan m\u00f3dszerekre \u00f6sszpontos\u00edt, mint a morfol\u00f3gia, a mikroszk\u00f3pia \u00e9s a v\u00e9konyr\u00e9teg-vizsg\u00e1lat. R\u00e1ad\u00e1sul a legt\u00f6bb \u00e1llati gy\u00f3gyszer hasonl\u00f3 \u00f6sszet\u00e9tel\u0171 aminosavakat \u00e9s nukleozidokat tartalmaz, ami szint\u00e9n k\u00e9t\u00e9rtelm\u0171s\u00e9ghez vezet az \u00e1llati gy\u00f3gyszerfajt\u00e1k azonos\u00edt\u00e1s\u00e1ban \u00e9s min\u0151s\u00e9gelemz\u00e9s\u00e9ben. Ez\u00e9rt l\u00e9tfontoss\u00e1g\u00fa, hogy az \u00e1llati gy\u00f3gyszerek min\u0151s\u00e9gellen\u0151rz\u00e9se \u00e9s \u00e9rt\u00e9kel\u00e9se \u00e9rdek\u00e9ben kiz\u00e1r\u00f3lagos analitikai m\u00f3dszereket dolgozzunk ki \u00e9s hozzunk l\u00e9tre az \u00e1llati gy\u00f3gyszerek azonos\u00edt\u00e1s\u00e1ra \u00e9s \u00e9rt\u00e9kel\u00e9s\u00e9re. Az elm\u00falt \u00e9vekben fokozatosan n\u00e9pszer\u0171s\u00edtett\u00e9k \u00e9s alkalmazt\u00e1k az \u00e1llati hagyom\u00e1nyos k\u00ednai gy\u00f3gyszerek min\u0151s\u00e9gellen\u0151rz\u00e9si modellj\u00e9t, amely a jellegzetes peptidek min\u0151s\u00e9gi\/kvantitat\u00edv elemz\u00e9s\u00e9n alapul. A K\u00ednai Gy\u00f3gyszerk\u00f6nyv 2020 tartalmazza a szam\u00e1rb\u0151r-ragaszt\u00f3, a szarvaskarika \u00e9s a tekn\u0151sp\u00e1nc\u00e9l-gyurma kiz\u00e1r\u00f3lagos peptidazonos\u00edt\u00e1si m\u00f3dszereit, de nincs a jellegzetes ionok azonos\u00edt\u00e1si m\u00f3dszere a f\u00f6ldi bog\u00e1rbog\u00e1rban.
\nAz ebben a tanulm\u00e1nyban meg\u00e1llap\u00edtott jellemz\u0151 ionokat feh\u00e9rjeem\u00e9szt\u00e9si technol\u00f3gi\u00e1val mutattuk ki, 1% amm\u00f3nium-bikarbon\u00e1t oldatot haszn\u00e1lva extrakci\u00f3s old\u00f3szerk\u00e9nt \u00e9s tripszint a minta enzimatikus hidrol\u00edzis\u00e9hez; A mint\u00e1k extrakci\u00f3s m\u00f3dszer\u00e9t, enzimadagol\u00e1s\u00e1t \u00e9s extrakci\u00f3s idej\u00e9t pedig megvizsg\u00e1ltuk, \u00e9s az optim\u00e1lis extrakci\u00f3s felt\u00e9teleket a reflux f\u0171t\u00e9s (extrakci\u00f3s m\u00f3dszer), 50 \u03bc L (enzimadagol\u00e1s) \u00e9s 30 perc (extrakci\u00f3s id\u0151) k\u00f6z\u00f6tt hat\u00e1roztuk meg.<\/p>\n

Mivel a K\u00ednai N\u00e9pk\u00f6zt\u00e1rsas\u00e1g gy\u00f3gyszerk\u00f6nyv\u00e9ben r\u00f6gz\u00edtett f\u00f6ldi bog\u00e1rf\u00e9reg min\u0151s\u00e9gellen\u0151rz\u00e9si m\u00f3dszere viszonylag egyszer\u0171, nem ritka, hogy a f\u00f6ldi bog\u00e1rf\u00e9reg piac\u00e1n hamis\u00edtott term\u00e9keket \u00e1ll\u00edtanak el\u0151 \u00e9s \u00e9rt\u00e9kes\u00edtenek, \u00e9s a gyeng\u00e9bb term\u00e9keket kiv\u00e1l\u00f3bbnak adj\u00e1k ki. Jelenleg a f\u00f6ldi bog\u00e1rf\u00e9reg \u00e1ra folyamatosan emelkedik a piacon. A gazdas\u00e1gi el\u0151ny\u00f6k \u00e9rdek\u00e9ben a t\u00f6rv\u00e9nyszeg\u0151k a nyeres\u00e9g n\u00f6vel\u00e9se \u00e9rdek\u00e9ben alum\u00edniumot, s\u00f3t \u00e9s m\u00e1s \u00f6sszetev\u0151ket adtak a f\u00f6ldi bog\u00e1rf\u00e9reg gy\u00f3gyszerhez, s\u0151t hamis\u00edtott term\u00e9kekkel helyettes\u00edtett\u00e9k az eredetieket. Ezenk\u00edv\u00fcl a Phnom Penh \u0151r\u00f6lt bog\u00e1rf\u00e9reg Guangdong tartom\u00e1nyban a hagyom\u00e1nyos k\u00ednai orvosl\u00e1s szabv\u00e1ny\u00e1ba is beker\u00fclt, \u00e9s hossz\u00fa ideje helyi h\u00e1ztart\u00e1si term\u00e9kk\u00e9nt haszn\u00e1lj\u00e1k. A kutat\u00e1sok azonban azt mutatj\u00e1k, hogy a Phnom Penh \u0151r\u00f6lt bog\u00e1r \u00f6sszet\u00e9tele elt\u00e9r az Eupolyphaga \u00e9s az Eupolyphaga \u00f6sszet\u00e9tel\u00e9t\u0151l; Ugyanakkor a k\u00fcl\u00f6nb\u00f6z\u0151 \u00e1llati gy\u00f3gyszerek standard f\u0151zete elvesztette a f\u0151zetdarabok alakj\u00e1t, \u00e9s nehezen azonos\u00edthat\u00f3. Ez\u00e9rt ez a tanulm\u00e1ny l\u00e9trehozta a t\u00f6megspektrometri\u00e1n alapul\u00f3 jellegzetes ionazonos\u00edt\u00e1si technol\u00f3gi\u00e1t. Meg\u00e1llap\u00edt\u00e1st nyert, hogy az m\/z 415,72 (kett\u0151s t\u00f6lt\u00e9s) \u2192 406,72, 415,72 (kett\u0151s t\u00f6lt\u00e9s) \u2192 667,34 karakterisztikus ionk\u00e9nt haszn\u00e1lhat\u00f3 a f\u00f6ldi bog\u00e1ncs sinensis azonos\u00edt\u00e1s\u00e1ra. A k\u00fcl\u00f6nb\u00f6z\u0151 forr\u00e1sokb\u00f3l sz\u00e1rmaz\u00f3 24 t\u00e9tel \u0151r\u00f6lt bog\u00e1rf\u00e9reg gy\u00f3gy\u00e1szati anyag, 21 t\u00e9tel \u0151r\u00f6lt bog\u00e1rf\u00e9reg kivonat, 6 t\u00e9tel \u0151r\u00f6lt bog\u00e1rf\u00e9reg k\u00e9sz\u00edtm\u00e9ny, 6 k\u00fcl\u00f6nb\u00f6z\u0151 \u00e1llati gy\u00f3gyszer \u00e9s 3 f\u00e9le \u0151r\u00f6lt bog\u00e1rf\u00e9reg hamis\u00edt\u00f3 anyag alkalmaz\u00e1s\u00e1val \u00e9s kimutat\u00e1s\u00e1val a kimutat\u00e1si m\u00f3dszer 2 k\u00fcl\u00f6nb\u00f6z\u0151 primit\u00edv \u0151r\u00f6lt bog\u00e1rf\u00e9regre alkalmazhat\u00f3, ami meger\u0151s\u00edti a jellemz\u0151 ion specifit\u00e1s\u00e1t, m\u00e9g akkor is, ha egy\u00e9rtelm\u0171en megk\u00fcl\u00f6nb\u00f6zteti az eredeti gy\u00f3gy\u00e1szati anyagok tulajdons\u00e1gait elvesztett \u0151r\u00f6lt bog\u00e1rf\u00e9reg tartalm\u00fa k\u00f6ztes term\u00e9keket \u00e9s k\u00e9sz\u00edtm\u00e9nyeket.
\nUgyanakkor ez a m\u00f3dszer egyszer\u0171en haszn\u00e1lhat\u00f3, nagym\u00e9rt\u00e9kben reproduk\u00e1lhat\u00f3, \u00e9s nincs \u00f6sszetett el\u0151feldolgoz\u00e1si folyamat, ami nagym\u00e9rt\u00e9kben cs\u00f6kkenti a m\u00f3dszer megval\u00f3s\u00edt\u00e1si k\u00fcsz\u00f6b\u00e9t. B\u00e1r sz\u00e1mos tanulm\u00e1ny kimutatta, hogy az \u00e1llati eredet\u0171 hagyom\u00e1nyos k\u00ednai gy\u00f3gyszerek azonos\u00edt\u00e1s\u00e1nak m\u00f3dszere a jellegzetes peptidek felhaszn\u00e1l\u00e1s\u00e1val \u00e9sszer\u0171 \u00e9s megval\u00f3s\u00edthat\u00f3, a vonatkoz\u00f3 min\u0151s\u00e9g\u00e9rt\u00e9kel\u00e9si m\u00f3dszereket m\u00e9g tov\u00e1bb kell gazdag\u00edtani \u00e9s fejleszteni, ami szint\u00e9n fontos ir\u00e1nya a hagyom\u00e1nyos k\u00ednai gy\u00f3gyszerek min\u0151s\u00e9gellen\u0151rz\u00e9s\u00e9nek j\u00f6v\u0151beli kutat\u00e1s\u00e1nak. \u00d6sszefoglalva, az ebben a tanulm\u00e1nyban meg\u00e1llap\u00edtott m\u00f3dszer hat\u00e9konyan kieg\u00e9sz\u00edti a f\u00f6ldi bog\u00e1r \u00e9s a f\u0151zetdarabok ellen\u0151rz\u00e9si szabv\u00e1nyainak hi\u00e1nyoss\u00e1gait, megoldja azt a probl\u00e9m\u00e1t, hogy a f\u00f6ldi bog\u00e1r hossz\u00fa id\u0151n kereszt\u00fcl csak a hagyom\u00e1nyos tapasztalatok r\u00e9v\u00e9n azonos\u00edtja a hiteless\u00e9get, jav\u00edtja a min\u0151s\u00e9gellen\u0151rz\u00e9s szintj\u00e9t, \u00e9s referenci\u00e1t biztos\u00edt a f\u00f6ldi bog\u00e1rhoz kapcsol\u00f3d\u00f3 klinikai gy\u00f3gyszerek biztons\u00e1goss\u00e1g\u00e1hoz \u00e9s hat\u00e9konys\u00e1g\u00e1hoz.<\/p>","protected":false},"excerpt":{"rendered":"

Identification of ground beetle sinensis and its preparation by characteristic ions The ground beetle worm was first recorded in Shennong’s Classic of Materia Medica, and was listed as the middle grade. Ground beetle sinensis Walker or Steleophaga plancyi (Boleny) is the dried female body of Eupolyphaga sinensis Walker or Steleophaga plancyi. The ground beetle beetle […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"gallery","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nIdentification of ground beetle sinensis and its preparation by characteristic ions - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/ground-beetle-sinensis\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Identification of ground beetle sinensis and its preparation by characteristic ions - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Identification of ground beetle sinensis and its preparation by characteristic ions The ground beetle worm was first recorded in Shennong’s Classic of Materia Medica, and was listed as the middle grade. Ground beetle sinensis Walker or Steleophaga plancyi (Boleny) is the dried female body of Eupolyphaga sinensis Walker or Steleophaga plancyi. The ground beetle beetle […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/longchangextracts.com\/hu\/ground-beetle-sinensis\/\" \/>\n<meta property=\"og:site_name\" content=\"China Chemical Manufacturer\" \/>\n<meta property=\"article:published_time\" content=\"2024-08-04T16:48:23+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-109.png\" \/>\n<meta name=\"author\" content=\"longcha9\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Szerz\u0151:\" \/>\n\t<meta name=\"twitter:data1\" content=\"longcha9\" \/>\n\t<meta name=\"twitter:label2\" content=\"Becs\u00fclt olvas\u00e1si id\u0151\" \/>\n\t<meta name=\"twitter:data2\" content=\"9 perc\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/\",\"url\":\"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/\",\"name\":\"Identification of ground beetle sinensis and its preparation by characteristic ions - China Chemical Manufacturer\",\"isPartOf\":{\"@id\":\"https:\/\/longchangextracts.com\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-109.png\",\"datePublished\":\"2024-08-04T16:48:23+00:00\",\"dateModified\":\"2024-08-04T16:48:23+00:00\",\"author\":{\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\"},\"breadcrumb\":{\"@id\":\"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/#breadcrumb\"},\"inLanguage\":\"hu\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"hu\",\"@id\":\"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/#primaryimage\",\"url\":\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-109.png\",\"contentUrl\":\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-109.png\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/longchangextracts.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Identification of ground beetle sinensis and its preparation by characteristic ions\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/longchangextracts.com\/#website\",\"url\":\"https:\/\/longchangextracts.com\/\",\"name\":\"China Chemical Manufacturer\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/longchangextracts.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"hu\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\",\"name\":\"longcha9\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"hu\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"caption\":\"longcha9\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Azonos\u00edt\u00e1sa f\u00f6ldi bog\u00e1r sinensis \u00e9s a k\u00e9sz\u00edtm\u00e9nyt jellemz\u0151 ionok - K\u00edna Chemical Manufacturer","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/longchangextracts.com\/hu\/ground-beetle-sinensis\/","og_locale":"hu_HU","og_type":"article","og_title":"Identification of ground beetle sinensis and its preparation by characteristic ions - China Chemical Manufacturer","og_description":"Identification of ground beetle sinensis and its preparation by characteristic ions The ground beetle worm was first recorded in Shennong’s Classic of Materia Medica, and was listed as the middle grade. Ground beetle sinensis Walker or Steleophaga plancyi (Boleny) is the dried female body of Eupolyphaga sinensis Walker or Steleophaga plancyi. The ground beetle beetle […]","og_url":"https:\/\/longchangextracts.com\/hu\/ground-beetle-sinensis\/","og_site_name":"China Chemical Manufacturer","article_published_time":"2024-08-04T16:48:23+00:00","og_image":[{"url":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-109.png"}],"author":"longcha9","twitter_card":"summary_large_image","twitter_misc":{"Szerz\u0151:":"longcha9","Becs\u00fclt olvas\u00e1si id\u0151":"9 perc"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/","url":"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/","name":"Azonos\u00edt\u00e1sa f\u00f6ldi bog\u00e1r sinensis \u00e9s a k\u00e9sz\u00edtm\u00e9nyt jellemz\u0151 ionok - K\u00edna Chemical Manufacturer","isPartOf":{"@id":"https:\/\/longchangextracts.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/#primaryimage"},"image":{"@id":"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/#primaryimage"},"thumbnailUrl":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-109.png","datePublished":"2024-08-04T16:48:23+00:00","dateModified":"2024-08-04T16:48:23+00:00","author":{"@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869"},"breadcrumb":{"@id":"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/#breadcrumb"},"inLanguage":"hu","potentialAction":[{"@type":"ReadAction","target":["https:\/\/longchangextracts.com\/ground-beetle-sinensis\/"]}]},{"@type":"ImageObject","inLanguage":"hu","@id":"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/#primaryimage","url":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-109.png","contentUrl":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-109.png"},{"@type":"BreadcrumbList","@id":"https:\/\/longchangextracts.com\/ground-beetle-sinensis\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/longchangextracts.com\/"},{"@type":"ListItem","position":2,"name":"Identification of ground beetle sinensis and its preparation by characteristic ions"}]},{"@type":"WebSite","@id":"https:\/\/longchangextracts.com\/#website","url":"https:\/\/longchangextracts.com\/","name":"K\u00edna Vegyi Gy\u00e1rt\u00f3","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/longchangextracts.com\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"hu"},{"@type":"Person","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869","name":"longcha9","image":{"@type":"ImageObject","inLanguage":"hu","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","caption":"longcha9"}}]}},"_links":{"self":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/5003"}],"collection":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/comments?post=5003"}],"version-history":[{"count":1,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/5003\/revisions"}],"predecessor-version":[{"id":5016,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/5003\/revisions\/5016"}],"wp:attachment":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/media?parent=5003"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/categories?post=5003"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/tags?post=5003"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}