{"id":4967,"date":"2024-08-04T16:40:14","date_gmt":"2024-08-04T16:40:14","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=4967"},"modified":"2024-08-04T16:40:14","modified_gmt":"2024-08-04T16:40:14","slug":"schisandra-chinensis","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/schisandra-chinensis\/","title":{"rendered":"A Schisandra chinensis gy\u00f3gy\u00e1szati anyagok UPLC ujjlenyomat\u00e1nak \u00e9s t\u00f6bbsz\u00f6r\u00f6s \u00e9rt\u00e9kel\u00e9si m\u00f3dszer\u00e9nek vizsg\u00e1lata"},"content":{"rendered":"<p>A Schisandra chinensis gy\u00f3gy\u00e1szati anyagok UPLC ujjlenyomat\u00e1nak \u00e9s t\u00f6bbsz\u00f6r\u00f6s \u00e9rt\u00e9kel\u00e9si m\u00f3dszer\u00e9nek vizsg\u00e1lata<br \/>\nA d\u00e9li Schisandra chinensis a Magnoliaceae csal\u00e1dba tartoz\u00f3 n\u00f6v\u00e9ny, m\u00edg a k\u00f6z\u00e9ps\u0151 Schisandra chinensis ugyanezen csal\u00e1dba tartoz\u00f3 n\u00f6v\u00e9ny A sz\u00e1r\u00edtott \u00e9s \u00e9rett gy\u00fcm\u00f6lcs\u00f6k et Wils. Meleg term\u00e9szet\u0171, savany\u00fa \u00e9s \u00e9des \u00edz\u0171, \u00f6sszeh\u00faz\u00f3, a qi-t toniz\u00e1l\u00f3 \u00e9s folyad\u00e9kot termel\u0151, a ves\u00e9ket toniz\u00e1l\u00f3 \u00e9s a sz\u00edvet nyugtat\u00f3 hat\u00e1s\u00fa. Olyan t\u00fcnetekre haszn\u00e1lj\u00e1k, mint a kr\u00f3nikus k\u00f6h\u00f6g\u00e9s \u00e9s zih\u00e1l\u00e1s, \u00e9jszakai emisszi\u00f3, gyakori enur\u00e9zis \u00e9s vizel\u00e9s, tart\u00f3s hasmen\u00e9s, spont\u00e1n izzad\u00e1s \u00e9s \u00e9jszakai izzad\u00e1s, folyad\u00e9kk\u00e1rosod\u00e1s \u00e9s szomj\u00fas\u00e1g, bels\u0151 h\u0151 \u00e9s szomj\u00fas\u00e1g csillap\u00edt\u00e1sa, sz\u00edvdobog\u00e1s \u00e9s \u00e1lmatlans\u00e1g. A Schisandra chinensis f\u0151 k\u00e9miai \u00f6sszetev\u0151i a triterpenoidok \u00e9s a lign\u00e1nok. Az elm\u00falt \u00e9vekben a kutat\u00e1sok kimutatt\u00e1k, hogy a Schisandra chinensis m\u00e1jv\u00e9d\u0151, nyugtat\u00f3 \u00e9s hipnotiz\u00e1l\u00f3, daganatellenes, v\u00e9rcukorszint-cs\u00f6kkent\u0151, antioxid\u00e1ns \u00e9s immuner\u0151s\u00edt\u0151 hat\u00e1s\u00fa. T\u00e1pl\u00e1l\u00f3 \u00e9s er\u0151s tulajdons\u00e1gokkal rendelkezik, valamint magas gy\u00f3gy\u00e1szati \u00e9s \u00e9tkez\u00e9si \u00e9rt\u00e9kkel b\u00edr.<br \/>\nA hagyom\u00e1nyos k\u00ednai orvosl\u00e1s min\u0151s\u00e9ge k\u00f6zvetlen\u00fcl \u00f6sszef\u00fcgg a klinikai kezel\u00e9s hat\u00e9konys\u00e1g\u00e1val. A hagyom\u00e1nyos k\u00ednai orvosl\u00e1s min\u0151s\u00e9g\u00e9nek hat\u00e9kony ellen\u0151rz\u00e9se a klinikai hat\u00e9konys\u00e1g biztos\u00edt\u00e1s\u00e1nak el\u0151felt\u00e9tele. Jelenleg az ujjlenyomat-technol\u00f3gi\u00e1t sz\u00e9les k\u00f6rben alkalmazz\u00e1k a hagyom\u00e1nyos k\u00ednai orvosl\u00e1s min\u0151s\u00e9gellen\u0151rz\u00e9s\u00e9ben. A hagyom\u00e1nyos k\u00ednai orvosl\u00e1s k\u00e9miai \u00f6sszetev\u0151inek \u00e1tfog\u00f3 jellemz\u00e9s\u00e9re alkalmas, \u00e9s a specifikuss\u00e1g \u00e9s a teljess\u00e9g jellemz\u0151ivel rendelkezik. Az ujjlenyomat \u00e9s a QAMS kombin\u00e1l\u00e1sa a hagyom\u00e1nyos k\u00ednai gy\u00f3gy\u00e1szat min\u0151s\u00e9g\u00e9nek \u00e1tfog\u00f3 ellen\u0151rz\u00e9se \u00e9rdek\u00e9ben mind min\u0151s\u00e9gi, mind mennyis\u00e9gi szempontb\u00f3l fontos m\u00f3dja a hagyom\u00e1nyos k\u00ednai gy\u00f3gy\u00e1szat moderniz\u00e1l\u00e1s\u00e1nak. Jelenleg a K\u00ednai N\u00e9pk\u00f6zt\u00e1rsas\u00e1g gy\u00f3gyszerk\u00f6nyv\u00e9nek 2020-as kiad\u00e1sa (a tov\u00e1bbiakban: K\u00ednai Gy\u00f3gyszerk\u00f6nyv) a Schisandra chinensis gy\u00f3gyn\u00f6v\u00e9ny eset\u00e9ben a schisandrin-metil-tartalom meghat\u00e1roz\u00e1s\u00e1ra szolg\u00e1l\u00f3 indik\u00e1tort haszn\u00e1lja. Egyetlen komponens beltartalm\u00e1nak meghat\u00e1roz\u00e1sa azonban m\u00e1r nem felel meg a hagyom\u00e1nyos k\u00ednai gy\u00f3gy\u00e1szat \u00e1tfog\u00f3 min\u0151s\u00e9gellen\u0151rz\u00e9si koncepci\u00f3j\u00e1nak.<br \/>\nJelenleg vannak kutat\u00e1si jelent\u00e9sek a Schisandra chinensis ujjlenyomat-spektrum\u00e1nak \u00e9s k\u00e9miai \u00f6sszet\u00e9tel\u00e9nek meg\u00e1llap\u00edt\u00e1s\u00e1r\u00f3l. Guo \u00e9s munkat\u00e1rsai nagy teljes\u00edtm\u00e9ny\u0171 folyad\u00e9kkromatogr\u00e1fi\u00e1t (HPLC) haszn\u00e1ltak a Schisandra chinensis \u00e9s a Schisandra chinensis ujjlenyomat-spektrum\u00e1nak meg\u00e1llap\u00edt\u00e1s\u00e1ra, \u00e9s k\u00e9miai mintafelismer\u0151 elemz\u00e9ssel kombin\u00e1lva n\u00e9gy k\u00fcl\u00f6nb\u00f6z\u0151 biomarkert sz\u0171rte ki, amelyek befoly\u00e1solj\u00e1k a Schisandra chinensis \u00e9s a Schisandra chinensis min\u0151s\u00e9g\u00e9t. Ma \u00e9s munkat\u00e1rsai HPLC-m\u00f3dszerrel l\u00e9trehozt\u00e1k a Schisandra chinensis ujjlenyomat\u00e1t, \u00e9s kvantitat\u00edvan elemezt\u00e9k az ujjlenyomat h\u00e9t ismert komponens\u00e9t. Wei et al. UPLC m\u00f3dszerrel l\u00e9trehozta a Schisandra chinensis ujjlenyomat\u00e1t, \u00e9s meghat\u00e1rozta a Schisandra chinensis h\u00e1rom f\u0151 hat\u00f3anyag\u00e1nak, nevezetesen a Wuweizi Jia, An Wu Zhi Su \u00e9s a Schisandrin-metil tartalm\u00e1t. A szok\u00e1sos folyad\u00e9kkromatogr\u00e1fi\u00e1val \u00f6sszehasonl\u00edtva az ultra-nagy teljes\u00edtm\u00e9ny\u0171 folyad\u00e9kkromatogr\u00e1fia haszn\u00e1lata ler\u00f6vid\u00edtheti az elemz\u00e9si id\u0151t, jav\u00edthatja a kromatogr\u00e1fi\u00e1s cs\u00facsok elv\u00e1laszt\u00e1s\u00e1t, \u00e9s nyilv\u00e1nval\u00f3 el\u0151ny\u00f6kkel rendelkezik az ujjlenyomat-spektrumok vizsg\u00e1lat\u00e1ban. A fenti vizsg\u00e1latok k\u00f6z\u00f6s probl\u00e9m\u00e1ja azonban a leg\u00e1lis referenciastandardok hi\u00e1nya \u00e9s a referenciastandardok t\u00falzott haszn\u00e1lata okozta k\u00f6lts\u00e9gn\u00f6veked\u00e9s. A Schisandra chinensis gy\u00f3gy\u00e1szati anyagok min\u0151s\u00e9gellen\u0151rz\u00e9s\u00e9re szolg\u00e1l\u00f3 egy teszt t\u00f6bbsz\u00f6r\u00f6s \u00e9rt\u00e9kel\u00e9si m\u00f3dszer alkalmaz\u00e1s\u00e1r\u00f3l m\u00e9g nem sz\u00e1moltak be. Ez a tanulm\u00e1ny UPLC ujjlenyomat- \u00e9s t\u00f6bbsz\u00f6r\u00f6s \u00e9rt\u00e9kel\u00e9st haszn\u00e1lt, kemometriai elemz\u00e9si m\u00f3dszerekkel kombin\u00e1lva, hogy \u00e1tfog\u00f3 min\u0151s\u00e9gellen\u0151rz\u00e9si vizsg\u00e1latot v\u00e9gezzen 14 t\u00e9tel Schisandra chinensis gy\u00f3gy\u00e1szati anyagon. Ez nemcsak referenciaanyagokat mentett meg, hanem alapot biztos\u00edtott a Schisandra chinensis min\u0151s\u00e9g\u00e9nek \u00e1tfog\u00f3, objekt\u00edv \u00e9s pontos \u00e9rt\u00e9kel\u00e9s\u00e9hez is.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4968\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-107.png\" alt=\"\" width=\"459\" height=\"425\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4969\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-93.png\" alt=\"\" width=\"810\" height=\"362\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-93.png 810w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-93-768x343.png 768w\" sizes=\"(max-width: 810px) 100vw, 810px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4970\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-89.png\" alt=\"\" width=\"810\" height=\"726\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-89.png 810w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-89-768x688.png 768w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-89-803x720.png 803w\" sizes=\"(max-width: 810px) 100vw, 810px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4971\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-78.png\" alt=\"\" width=\"810\" height=\"669\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-78.png 810w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-78-768x634.png 768w\" sizes=\"(max-width: 810px) 100vw, 810px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4972\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-72.png\" alt=\"\" width=\"810\" height=\"404\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-72.png 810w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-72-768x383.png 768w\" sizes=\"(max-width: 810px) 100vw, 810px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4973\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-64.png\" alt=\"\" width=\"810\" height=\"387\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-64.png 810w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-64-768x367.png 768w\" sizes=\"(max-width: 810px) 100vw, 810px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4974\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-60.png\" alt=\"\" width=\"810\" height=\"276\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-60.png 810w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-60-768x262.png 768w\" sizes=\"(max-width: 810px) 100vw, 810px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4975\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-54.png\" alt=\"\" width=\"604\" height=\"541\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4976\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-48.png\" alt=\"\" width=\"604\" height=\"672\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4977\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-41.png\" alt=\"\" width=\"810\" height=\"377\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-41.png 810w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-41-768x357.png 768w\" sizes=\"(max-width: 810px) 100vw, 810px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4978\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/11-35.png\" alt=\"\" width=\"810\" height=\"344\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/11-35.png 810w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/11-35-768x326.png 768w\" sizes=\"(max-width: 810px) 100vw, 810px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4979\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/12-31.png\" alt=\"\" width=\"810\" height=\"356\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/12-31.png 810w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/12-31-768x338.png 768w\" sizes=\"(max-width: 810px) 100vw, 810px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4980\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/13-26.png\" alt=\"\" width=\"809\" height=\"337\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/13-26.png 809w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/13-26-768x320.png 768w\" sizes=\"(max-width: 809px) 100vw, 809px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4981\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/14-22.png\" alt=\"\" width=\"810\" height=\"512\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/14-22.png 810w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/14-22-768x485.png 768w\" sizes=\"(max-width: 810px) 100vw, 810px\" \/>A K\u00ednai Gy\u00f3gyszerk\u00f6nyv 2020-as kiad\u00e1sa el\u0151\u00edrja, hogy a Schisandra chinensis gy\u00f3gyn\u00f6v\u00e9nyt akkor kell betakar\u00edtani, amikor a gy\u00fcm\u00f6lcs \u0151sszel meg\u00e9rik. A szakirodalom szerint Li \u00e9s munkat\u00e1rsai h\u00e1rom term\u0151ter\u00fcletr\u0151l, Hubeib\u0151l, Szecsu\u00e1nb\u00f3l \u00e9s Csianghszib\u00f3l sz\u00e1rmaz\u00f3 Schisandra chinensis gy\u00f3gyn\u00f6v\u00e9nyekben a f\u0151 k\u00e9miai komponensek tartalm\u00e1nak v\u00e1ltoz\u00e1s\u00e1t tanulm\u00e1nyozt\u00e1k. A m\u00e9r\u00e9si eredm\u00e9nyek elemz\u00e9s\u00e9vel meg\u00e1llap\u00edtott\u00e1k, hogy a Schisandra chinensis gy\u00f3gy\u00e1szati anyagokban a f\u0151 k\u00e9miai komponensek felhalmoz\u00f3d\u00e1sa a h\u00e1rom term\u0151ter\u00fclet k\u00fcl\u00f6nb\u00f6z\u0151 n\u00f6veked\u00e9si szakaszaiban bizonyos mint\u00e1zatot mutat; A Schisandra chinensis optim\u00e1lis betakar\u00edt\u00e1si id\u0151szak\u00e1t el\u0151zetesen szeptember k\u00f6zep\u00e9re \u00e9s v\u00e9g\u00e9re hat\u00e1rozt\u00e1k meg. Huang \u00e9s munkat\u00e1rsai UV-spektrofotometri\u00e1t \u00e9s folyad\u00e9kkromatogr\u00e1fi\u00e1t haszn\u00e1ltak az ill\u00f3olaj, az \u00f6sszes lign\u00e1n, a skizandrin \u00e9s a skizandrin tartalm\u00e1nak meghat\u00e1roz\u00e1s\u00e1ra a Shaanxi tartom\u00e1nyban termesztett Schisandra chinensisben k\u00fcl\u00f6nb\u00f6z\u0151 betakar\u00edt\u00e1si id\u0151szakokban. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy a Schisandra chinensis optim\u00e1lis betakar\u00edt\u00e1si id\u0151szaka augusztus eleje. Emellett a vizsg\u00e1latok kimutatt\u00e1k, hogy a k\u00fcl\u00f6nb\u00f6z\u0151 r\u00e9gi\u00f3kban alkalmazott k\u00fcl\u00f6nb\u00f6z\u0151 feldolgoz\u00e1si m\u00f3dszerek jelent\u0151s hat\u00e1ssal vannak a Schisandra chinensis hat\u00f3anyag-tartalm\u00e1ra. Ez a tanulm\u00e1ny meg\u00e1llap\u00edtotta, hogy a hat lign\u00e1n teljes tartalma a Hubei tartom\u00e1nyb\u00f3l sz\u00e1rmaz\u00f3 \u00f6t Schisandra chinensis-t\u00e9telben volt a legmagasabb, m\u00edg a fennmarad\u00f3 kilenc, Shaanxi, Henan \u00e9s Shanxi tartom\u00e1nyb\u00f3l sz\u00e1rmaz\u00f3 t\u00e9telek tartalma viszonylag egyenletes volt, \u00e9s a Shanxi tartom\u00e1nyb\u00f3l sz\u00e1rmaz\u00f3 h\u00e1rom t\u00e9tel tartalma volt a legalacsonyabb; Ezenk\u00edv\u00fcl a protokatechuic sav tartalma Henanban volt a legmagasabb, majd Hubei k\u00f6vetkezett, \u00e9s Shaanxi \u00e9s Shanxi tartom\u00e1nyban volt a legalacsonyabb. Ez \u00f6sszef\u00fcgghet a gy\u00f3gyn\u00f6v\u00e9nyek eredet\u00e9ben, betakar\u00edt\u00e1si idej\u00e9ben \u00e9s feldolgoz\u00e1si m\u00f3dszereiben mutatkoz\u00f3 k\u00fcl\u00f6nbs\u00e9gekkel.<br \/>\nEz a tanulm\u00e1ny UPLC-t haszn\u00e1lt a Schisandra chinensis gy\u00f3gy\u00e1szati anyagok ujjlenyomat-spektrum\u00e1nak meg\u00e1llap\u00edt\u00e1s\u00e1ra, \u00e9s k\u00fcl\u00f6nb\u00f6z\u0151 mobilf\u00e1zis-rendszereket vizsg\u00e1lt (metanol-v\u00edz, acetonitril-v\u00edz \u00e9s acetonitril-0,1% foszforsav). Az eredm\u00e9nyek azt mutatt\u00e1k, hogy az acetonitril-0,1% foszforsav el\u00faci\u00f3s rendszerk\u00e9nt t\u00f6rt\u00e9n\u0151 alkalmaz\u00e1sa \u00e1tfog\u00f3 kromatogr\u00e1fi\u00e1s cs\u00facsinform\u00e1ci\u00f3t \u00e9s j\u00f3 elv\u00e1laszt\u00e1si hat\u00e9konys\u00e1got eredm\u00e9nyezett. A Schisandra chinensis tesztoldat teljes hull\u00e1mhossz\u00fa letapogat\u00e1s\u00e1t di\u00f3dasoros detektorral (DAD detektor) v\u00e9gezt\u00fck a 190-350 nm-es tartom\u00e1nyban, \u00e9s az \u00f6sszehasonl\u00edt\u00e1shoz k\u00fcl\u00f6nb\u00f6z\u0151 hull\u00e1mhosszakon (230, 254 nm) ujjlenyomat-spektrumokat vontunk ki. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy 230 nm-en az ujjlenyomat-spektrumokban a kromatogr\u00e1fi\u00e1s cs\u00facsok v\u00e1lasza \u00e9s kapacit\u00e1sa j\u00f3 volt. Vizsg\u00e1ltuk tov\u00e1bb\u00e1 a k\u00fcl\u00f6nb\u00f6z\u0151 oszlophossz\u00fas\u00e1gok [Waters ACQUITY HSS T3 (2,1mm \u00d7 100mm, 1,8 \u03bc m), Waters ACQUITY HSS T3 (2,1mm \u00d7 150mm, 1,8 \u03bc m)] elv\u00e1laszt\u00e1si hat\u00e9konys\u00e1g\u00e1t a Schisandra chinensis gy\u00f3gy\u00e1szati anyagok ujjlenyomat-spektrum\u00e1ra. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy a Waters ACQUITY HSS T3 (2,1 mm \u00d7 150 mm, 1,8 \u03bc m) oszlop jobb elv\u00e1laszt\u00e1si hat\u00e9konys\u00e1ggal rendelkezett. Ezenk\u00edv\u00fcl egyt\u00e9nyez\u0151s elemz\u00e9ssel megvizsg\u00e1ltuk az extrakci\u00f3s old\u00f3szer, az extrakci\u00f3s m\u00f3dszer \u00e9s az extrakci\u00f3s id\u0151 hat\u00e1s\u00e1t a Schisandra chinensis ujjlenyomat-spektrum\u00e1ra \u00e9s a tartalom meghat\u00e1roz\u00e1s\u00e1ra, a \"teljes cs\u00facster\u00fclet\/az ujjlenyomat-spektrum mintam\u00e9rete\" \u00e9s a hat lign\u00e1n tartalma mint \u00e9rt\u00e9kel\u00e9si mutat\u00f3k seg\u00edts\u00e9g\u00e9vel. Meghat\u00e1roztuk a vizsg\u00e1lati oldat elk\u00e9sz\u00edt\u00e9s\u00e9nek optim\u00e1lis m\u00f3dszer\u00e9t, hogy az ujjlenyomat-spektrum egyes cs\u00facsainak legnagyobb extrakci\u00f3s hat\u00e9konys\u00e1g\u00e1t \u00e9rj\u00fck el.<br \/>\nJelenleg a k\u00e9miai mintafelismer\u00e9si m\u00f3dszereket, mint p\u00e9ld\u00e1ul az ujjlenyomat-hasonl\u00f3s\u00e1g \u00e9rt\u00e9kel\u00e9s\u00e9t, az euklideszi t\u00e1vols\u00e1g klaszterez\u0151 elemz\u00e9st \u00e9s a f\u0151komponens-elemz\u00e9st sz\u00e9les k\u00f6rben haszn\u00e1lj\u00e1k olyan kutat\u00e1si ter\u00fcleteken, mint a k\u00ednai gy\u00f3gy\u00e1szati anyagok min\u0151s\u00e9g\u00e9nek, eredetk\u00fcl\u00f6nbs\u00e9g\u00e9nek \u00e9s fajtaazonos\u00edt\u00e1s\u00e1nak vizsg\u00e1lata. Ez a tanulm\u00e1ny ujjlenyomat-hasonl\u00f3s\u00e1gi \u00e9rt\u00e9kel\u00e9si elemz\u00e9st, klaszterelemz\u00e9st \u00e9s ortogon\u00e1lis parci\u00e1lis legkisebb n\u00e9gyzetek diszkriminancia-elemz\u00e9st vezet be a Schisandra chinensis mint\u00e1k k\u00fcl\u00f6nb\u00f6z\u0151 t\u00e9telei k\u00f6z\u00f6tti ujjlenyomatmint\u00e1k hasonl\u00f3s\u00e1g\u00e1nak \u00e9s rokons\u00e1g\u00e1nak vizu\u00e1lis m\u00e9r\u00e9s\u00e9re. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy a 14 t\u00e9tel Schisandra chinensis gy\u00f3gy\u00e1szati anyag \u00e9s a kontroll ujjlenyomat spektrumok k\u00f6z\u00f6tti hasonl\u00f3s\u00e1g 0,95 felett volt, ami j\u00f3 konzisztenci\u00e1t jelez a k\u00fcl\u00f6nb\u00f6z\u0151 eredet\u0171 Schisandra chinensis gy\u00f3gy\u00e1szati anyagok k\u00f6z\u00f6tt. A klaszterelemz\u00e9s \u00e9s az ortogon\u00e1lis r\u00e9szleges legkisebb n\u00e9gyzetek diszkriminancia-anal\u00edzise r\u00e9v\u00e9n a Schisandra chinensis gy\u00f3gy\u00e1szati anyagok 14 t\u00e9tele 4 kateg\u00f3ri\u00e1ba sorolhat\u00f3, ami bizonyos sz\u00e1rmaz\u00e1si szab\u00e1lyoss\u00e1got mutat; \u00f6sszesen 9 differenci\u00e1lis anyagot vizsg\u00e1ltak, nevezetesen az 1. cs\u00facsot (protokatechuic sav), a 2. cs\u00facsot, a 4. cs\u00facsot, a 6. cs\u00facsot, a 7. cs\u00facsot (schisandrin \u00e9szter B), a 8. cs\u00facsot, a 9. cs\u00facsot, a 12. cs\u00facsot \u00e9s a 15. cs\u00facsot, ami azt mutatja, hogy a fenti 9 \u00f6sszetev\u0151 jelent\u0151s hat\u00e1st gyakorol a Schisandra chinensis ujjlenyomat\u00e1ra. Tov\u00e1bbi m\u00e9lyrehat\u00f3 kutat\u00e1sra van sz\u00fcks\u00e9g. Ez a k\u00eds\u00e9rlet a Schisandra chinensisben l\u00e9v\u0151 lign\u00e1nok szerkezeti hasonl\u00f3s\u00e1g\u00e1t haszn\u00e1lta fel a Schisandra chinensis gy\u00f3gy\u00e1szati anyagokban l\u00e9v\u0151 hat lign\u00e1n tartalm\u00e1nak QAMS seg\u00edts\u00e9g\u00e9vel t\u00f6rt\u00e9n\u0151 el\u0151zetes meghat\u00e1roz\u00e1si m\u00f3dszer\u00e9nek l\u00e9trehoz\u00e1s\u00e1ra. A Schisandrin A, Schisandrin C, Schisandrin B, Amphotericin, Schisandrin A \u00e9s Schisandrin D kiv\u00e1lasztott \u00f6sszetev\u0151i ebben a tanulm\u00e1nyban bizonyos biol\u00f3giai aktivit\u00e1sokkal rendelkeznek a Schisandra chinensis gy\u00f3gy\u00e1szati anyagokban, amelyek t\u00fckr\u00f6zhetik a gy\u00f3gy\u00e1szati anyagok bels\u0151 min\u0151s\u00e9g\u00e9t. K\u00f6z\u00fcl\u00fck a Schisandra A \u00e9szter stabil k\u00e9miai tulajdons\u00e1gokkal rendelkezik, \u00e9s reprezentat\u00edv bels\u0151 referenciak\u00e9nt. A QAMS m\u00f3dszer \u00e9s a k\u00fcls\u0151 standard m\u00f3dszer relat\u00edv hib\u00e1inak \u00f6sszehasonl\u00edt\u00e1s\u00e1val az eredm\u00e9nyek azt mutatt\u00e1k, hogy a Schisandra chinensis tartalom meghat\u00e1roz\u00e1s\u00e1ban nem volt jelent\u0151s k\u00fcl\u00f6nbs\u00e9g a bev\u00e1lt QAMS m\u00f3dszer \u00e9s a k\u00fcls\u0151 standard m\u00f3dszer k\u00f6z\u00f6tt, ami azt jelzi, hogy a bev\u00e1lt m\u00f3dszer j\u00f3 hiteless\u00e9ggel rendelkezik.<br \/>\nEz a tanulm\u00e1ny az ujjlenyomat-elemz\u00e9s \u00e9s a t\u00f6bbsz\u00f6r\u00f6s \u00e9rt\u00e9kel\u00e9s kombin\u00e1ci\u00f3j\u00e1t alkalmazta a Schisandra chinensis gy\u00f3gy\u00e1szati anyagok min\u0151s\u00e9g\u00e9nek min\u0151s\u00e9gi \u00e9s mennyis\u00e9gi \u00e9rt\u00e9kel\u00e9s\u00e9re, amely referenci\u00e1t ny\u00fajthat a Schisandra chinensis gy\u00f3gy\u00e1szati anyagok min\u0151s\u00e9gi szabv\u00e1nyainak jav\u00edt\u00e1s\u00e1hoz.<\/p>","protected":false},"excerpt":{"rendered":"<p>Study on UPLC fingerprint and multi evaluation method of Schisandra chinensis medicinal materials South Schisandra chinensis is a plant of the Magnoliaceae family, while Central Schisandra chinensis is a plant of the same family Dried and ripe fruits of et Wils. It is warm in nature, sour and sweet in taste, and has the effects [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Study on UPLC fingerprint and multi evaluation method of Schisandra chinensis medicinal materials - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/schisandra-chinensis\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study on UPLC fingerprint and multi evaluation method of Schisandra chinensis medicinal materials - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Study on UPLC fingerprint and multi evaluation method of Schisandra chinensis medicinal materials South Schisandra chinensis is a plant of the Magnoliaceae family, while Central Schisandra chinensis is a plant of the same family Dried and ripe fruits of et Wils. 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